On the Blog: States should use federal funds to address drivers of
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The Latest Research, Commentary, And News From Health Affairs

Wednesday, November 17, 2021

Dear John,

In the November issue, Kevin Outterson estimates the appropriate size of
global pull incentives for antibacterial medicines.

Financial Incentives For Antibacterials

Even with direct funding, it is difficult to generate investments for
the development of low-volume drugs
,
given low expected revenue from sales. This is the case with
antibacterials. As a consequence, policy makers have adopted "pull"
incentives that provide a separate payment stream.

Kevin Outterson modeled various drug development scenarios and concluded
that incentives "totaling several billion dollars per drug globally are
required to make antibacterial [research and development] projects
economically attractive to commercial sponsors."

"The amounts in the proposed Pioneering Antibiotic Subscriptions to End
Upsurging Resistance (PASTEUR) Act of 2021 and a UK pilot program are
well within the bounds of an effective antibacterial pull incentive," he
found.

Outterson gave readers further insight into his research at a recent
Health Affairs Journal Club. To learn more about opportunities like
this, visit our events page .

Today on Health Affairs Blog, Mandy Cohen and coauthors recommend ways
that states can spend federal funds to strengthen services that address
drivers of health

such as affordable housing, access to healthy food, and childcare.

Katie Keith discusses the Center for Medicare and Medicaid Services'
first weekly update of the 2022 open enrollment period
,
noting that enrollment remains strong, presumably driven by continued
enhanced subsidies under the American Rescue Plan Act.

Elevating Voices: Native American Heritage Month: In her Narrative
Matters essay calling for new mid-level dental providers
,
Lakota dental hygienist Maxine Brings Him Back-Janis describes how
"inadequate dental services, flawed systems delivering dental care, and
punishing poverty all contribute to [her] reservation's crisis in oral
health."

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today .

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Your Daily Digest

Estimating The Appropriate Size Of Global Pull Incentives For
Antibacterial Medicines

Kevin Outterson

Using Federal Funds To Address Drivers Of Health For COVID-19 Recovery
And Beyond

Mandy K. Cohen et al.

First HealthCare.gov Enrollment Report; More Basic Health Plan Money For
MN, NY

Katie Keith

A Dental Hygienist Who's A Lakota Sioux Calls For New Mid-Level Dental
Providers

Maxine Brings Him Back-Janis

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