The Latest Research, Commentary, And News From Health Affairs
Wednesday, November 17, 2021
Dear John,
In the November issue, Kevin Outterson estimates the appropriate size of global pull incentives for antibacterial medicines.
Financial Incentives For Antibacterials
Even with direct funding, it is difficult to generate investments for the development of low-volume drugs, given low
expected revenue from sales. This is the case with antibacterials. As a consequence, policy makers have adopted "pull" incentives that provide a separate payment stream.
Kevin Outterson modeled various drug development scenarios and concluded that incentives "totaling several billion dollars per drug globally are required to make antibacterial [research and development] projects economically attractive to commercial sponsors."
"The amounts in the proposed Pioneering Antibiotic Subscriptions to End Upsurging Resistance (PASTEUR) Act of 2021 and a UK pilot program are well
within the bounds of an effective antibacterial pull incentive," he found.
Outterson gave readers further insight into his research at a recent Health Affairs Journal Club. To learn more about opportunities like this, visit our events page.
Today on Health Affairs Blog, Mandy Cohen and coauthors recommend ways that states can spend federal funds to strengthen services that address drivers of health such as affordable housing, access to healthy food, and childcare.
Katie Keith discusses the Center for Medicare and Medicaid Services' first weekly update of the 2022 open enrollment period, noting that enrollment remains
strong, presumably driven by continued enhanced subsidies under the American Rescue Plan Act.
Elevating Voices: Native American Heritage Month: In her Narrative Matters essay calling for new mid-level dental providers, Lakota dental hygienist Maxine Brings Him Back-Janis describes how "inadequate dental services, flawed systems delivering dental care, and punishing poverty all contribute to [her] reservation’s crisis in oral health."
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