From Dr. Maria C. Carrillo, Alzheimer's Association <[email protected]>
Subject What’s the latest news from the Alzheimer’s Association International Conference®?
Date July 29, 2025 6:16 PM
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Revealing research breakthroughs
for Alzheimer's care.

Alzheimer's Association

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Breakthrough updates are in at AAIC.

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Dear Friend,

The Alzheimer's Association
International Conference® 2025 (AAIC®) contains the latest
advances on every aspect of dementia research and care. The world's
leading researchers, clinicians and dementia professionals are sharing
breaking research discoveries and important updates that could lead to
new methods of treatment and prevention.

Whether or not you are joining us at
AAIC in Toronto or online, rest assured that your presence is evident
in every session and workshop taking place. Along with funding care
and support resources and cutting-edge research impacting clinical
care,
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your first gift today will make events like this possible - and
ensure progress continues long after this year's AAIC ends.

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MAKE YOUR FIRST GIFT TODAY
>>

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It's only with your support that we can deliver on the promise
of what we learn here at AAIC - and further our mission to lead
the way to end Alzheimer's and all other dementia - by
accelerating global research, driving risk reduction and early
detection, and maximizing quality care and support.

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We're excited to report that results from the U.S. POINTER
study - a two-year clinical trial to evaluate whether lifestyle
interventions that simultaneously target many risk factors protect
cognitive function in older adults who are at risk for cognitive
decline - were presented at AAIC, and the findings give us hope.

The Key Findings:

* U.S. POINTER found that, in people at risk for cognitive decline
and dementia, a multidomain lifestyle intervention improved
cognitive function over two years - with even greater
improvement from a more intense intervention - protecting
cognition from normal age-related decline for nearly two years.
* This means that, relative to the self-guided group, participants
in the structured group performed at a level comparable to
adults 1 to 2 years younger in age - an effect that likely
increases resilience against cognitive decline.

These positive results underscore the message that healthy
behavior has a powerful impact on brain health. With your help, over
the next four years, we'll invest $40 million to bring the U.S.
POINTER recipe into communities around the country. This includes an
extension of the trial to follow U.S. POINTER participants to
understand the longer-term impact of these lifestyle interventions, as
well as collaborations with health systems and health agencies to turn
the trial findings into action for people in all communities. Here are
several initiatives you can expect to see in the coming months:

* A personal brain health assessment tool to help people create
their own brain health game plan
* An interactive, case-based virtual brain health training program
to help health care providers promote brain health among their
patients
* A brain health and dementia-capable Community Recognition
Program to recognize employers, health care systems and
communities that champion brain health and deliver quality care
and support
* A Brain Health Roundtable to bring together the brightest minds
among health care, public health, community and corporate
leaders.

We are in a new era in brain health. This was one of the
largest and most ambitious lifestyle intervention trials for brain
health in United States history. The results will have a real impact
on Americans for generations to come - but it is just the
beginning.

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Kind-hearted people like you who support Alzheimer's research
make the U.S. POINTER study and other clinical trials possible. To
learn more about research breakthroughs, I encourage you to register
and attend AAIC For All: Community. This no-cost, single day community
event will be held both online and in person on July 31, where global
experts will showcase research highlights from AAIC 2025 and expand
your knowledge of dementia, diagnosis, treatment, risk reduction and
dementia care.

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I'm excited to think about the exchange of ideas happening
this week at AAIC. As you read about new breakthroughs, there's a good
chance many of them may have started with the people at this year's
conference. That's not only a reflection on those researchers,
scientists and healthcare professionals - it's also a reflection
on the strength of our community's commitment.

With appreciation,

Maria C. Carrillo, Ph.D.

Chief Science Officer and Medical
Affairs Lead

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P.S. Friend, there is
still time to take part in AAIC For All: Community to learn about the
latest research findings, either in person or online, on July 31.
Please consider taking part. We're thrilled to allow our supporters
access to groundbreaking research in Alzheimer's and dementia clinical
care and science, wherever they are. We hope you are encouraged by
what you hear and that you'll be inspired to
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join us in the fight with a gift today.

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DONATE NOW >>

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Your donation will strengthen our efforts
to advance Alzheimer's care, support and research. From face-to-face
support to online education programs and promising global research
initiatives, your gift makes a difference in the lives of all those
affected by Alzheimer's and other dementias in your community and
across the world. Thank you for your continued support.

Alzheimer's Association Home Office, 225
N. Michigan Ave., Fl. 17, Chicago, IL 60601

© 2025 Alzheimer's
Association. All rights reserved.
800.272.3900 | alz.org

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