View online [[link removed]}&lead=419599&emailid=83844&nl=daily] |
Unsubscribe (one-click)
[[link removed]}&lead=419599&emailid=83844&nl=daily]
[[link removed]}&lead=419599&emailid=83844&nl=daily]
-------------------------
- The top 25 stories curated by editors and fellow readers!
From the Editor's Desk
Pfizer's activist troubles, gene therapy questions, RFK Jr.'s MAHA
ambitions - STAT
Will an activist investor campaign against Pfizer lead to big changes
at the struggling pharma giant? Why are some experts questioning the
regulatory standards used to approve gene therapies for Duchenne
muscular dystrophy? What’s the difference between Novo Holdings and
Novo Nordisk, and will it impact a $16 billion acquisition of
Catalent? And what lies ahead for Robert F. Kennedy Jr. and the Make
America Healthy Again movement?
We talk about all that and more on this week’s episode of “The
Readout LOUD,” STAT’s biotech podcast. In our “Chatty Cathy”
segment, we mull over Starboard Value’s criticisms of Pfizer and
what changes, including the replacement of CEO Albert Bourla, might
lie ahead. We also discuss the impact that Pfizer’s failed gene
therapy in Duchenne may have on other companies developing
next-generation treatments, and noodle over Novo Holdings’
controversial plan to acquire Catalent, one of the world’s largest
contract drug manufacturers.
Continued here [[link removed]}&lead=419599&emailid=83844&nl=daily]
_TradeBriefs: Newsletters for Decision-Makers!_
Work
Three journalists killed in Israeli strike in southern Lebanon, media
report
[[link removed]}&lead=419599&emailid=83844&nl=daily]
An Israeli strike early on Friday morning killed at least three
journalists as they slept in a guesthouse in Hasbaya in southern
Lebanon, Lebanese media reported.
Work
Donald Trump and the F-Word - The New Yorker
[[link removed]}&lead=419599&emailid=83844&nl=daily]
Donald Trump is closing crazy. Does it matter? For the historical
record, let it be noted that, with less than two weeks until his third
and likely final Presidential election, Trump in recent days has
talked about Arnold Palmers penis size and how Joe Biden actually
likes him better than Kamala Harris. He has made digressions on the
history of paper clips and why teleprompters are stupid and possibly
dangerous. He has suggested that Harris is drinking or on drugs, that
she choked like a dog on The View, and that she is a shit
Vice-President. He has complained that wind power is killing birds and
stopping people from watching television. Of his own much-critiqued
ramblings, he has insisted, People say its total genius.
Work
A Simple Exercise to Help You Check Your Biases - Harvard Business
Review [[link removed]}&lead=419599&emailid=83844&nl=daily]
The corporate diversity, equity, and inclusion (DEI) sector is at a
crossroads. Two decades of rigorous research built the business case
for DEI efforts. Studies consistently show that racially diverse teams
outperform their competitors in terms of profitability, and
corporations with women comprising more than a quarter of their
executive committees realize 10 times higher profit margin than those
with no female board members.
Work
Here's What to Do When It Feels Like Everyone Doubts You - Inc
[[link removed]}&lead=419599&emailid=83844&nl=daily]
Recently, I invited an experienced luxury hotelier to visit the new
campus we were building near Santa Fe for Modern Elder Academy, the
midlife wisdom school I co-founded in 2018. Looking out at the
2,566-acre site, he remarked, Youre quite a risk-taker. Hes not wrong,
but his tone was more cautionary than it was cheerleading. My
entrepreneurial balloon of confidence popped.
Work
New wearable devices target the brain to bring better sleep - WSJ (No
paywall) [[link removed]}&lead=419599&emailid=83844&nl=daily]
New gadgets that target the brain promise to speed up the onset of
sleep, improve the length and quality of rest, and even transition
travelers to a different time zone before their planes touch down.
Work
Israels endgame in Gaza: Finish off Hamas where the war started - WSJ
(No paywall) [[link removed]}&lead=419599&emailid=83844&nl=daily]
A year into the war in Gaza, Israel is back at the site of its first
battles and engaged in one of the most ferocious campaigns of the
conflict, a do-over that offers a cautionary tale for its other war in
Lebanon.
Work
New Call of Duty tests Microsofts $75 billion bet on future of
videogames - WSJ (No paywall) [[link removed]}&lead=419599&emailid=83844&nl=daily]
Microsoft is facing the biggest test yet of its $75 billion bet on
videogames: the release of a new installment of the Call of Duty"
franchise on its Game Pass subscription service, which customers will
be able to access for the first time on Friday.
Work
Elon Musks secret conversations with Vladimir Putin - WSJ (No paywall)
[[link removed]}&lead=419599&emailid=83844&nl=daily]
At one point, Putin asked the billionaire to avoid activating his
Starlink satellite internet service over Taiwan as a favor to Chinese
leader Xi Jinping, said two people briefed on the request.
Work
Inside Trump worlds prep for a second term - WSJ (No paywall)
[[link removed]}&lead=419599&emailid=83844&nl=daily]
Anyone associated with the Heritage Foundations Project 2025, which
Trump and his advisers denounced after it became a political target
for Democrats, would be barred from working on the team. Transition
staff used Control+F," a keyboard shortcut, to search through Project
2025s 900-plus-page policy blueprint for the names of potential hires.
Work
Gucci has problems. The biggest may be a safe new look - WSJ (No
paywall) [[link removed]}&lead=419599&emailid=83844&nl=daily]
Kering, the French luxury group that is Guccis owner, issued its third
profit warning of the year on Wednesday evening as it unveiled
quarterly results and now expects 2024 operating income to be barely
half last years levels. Its star brand is weak. Sales at Gucci fell
25% in the third quarter compared with the same period of 2023. The
label has been shrinking for more than a year and its performance has
fallen behind rival fashion brands at luxury giant LVMH.
Work
Boeings strike is still on. Its strained balance sheet makes matters
worse. - WSJ (No paywall) [[link removed]}&lead=419599&emailid=83844&nl=daily]
Boeings new chief executive Kelly Ortberg has many active fronts in
his battle to reset" the company, including addressing labor strikes,
re-establishing a culture of accountability, fixing ongoing problems
at the defense division and figuring out how to build innovative plane
models again.
Work
Ukrainian medics face blasts, bloodshed in front-line hospitals - WSJ
(No paywall) [[link removed]}&lead=419599&emailid=83844&nl=daily]
In the relative safety of their bunker, which lies under 10 feet of
sandbags, earth, steel and pine logs, surgeon Yevhen Antoniuk and his
team got to work. After 30 minutes, they had stabilized the soldier
and sent him farther from the front line for additional treatment.
Work
Teslas costly AI ambitions helped by earnings rebound - WSJ (No
paywall) [[link removed]}&lead=419599&emailid=83844&nl=daily]
How he will fund that future is coming under sharper scrutiny. Musk is
under pressure to wring better profitability from the core auto
business to help pay for those moonshot bets.
Work
How Hezbollah is hitting back after being pummeled by Israel - WSJ (No
paywall) [[link removed]}&lead=419599&emailid=83844&nl=daily]
BEIRUTAfter suffering a series of punishing blows by Israel, Hezbollah
is fighting back, launching ambushes on Israeli troops in Lebanon and
ratcheting up drone and missile strikes deeper into Israel.
Work
How To Now Get Nearly Unlimited Funding To Build Your Small Business
Empire
[[link removed]}&lead=419599&emailid=83844&nl=daily]
The golden ticket to buy a small business has always been a Small
Business Administration 7(a) loan. But thanks to a recent and
overlooked rule change, it just got even better, giving ambitious
entrepreneurs a chance to build a diversified collection of small
businesses–their own baby Berkshire Hathaways.
Work
Astronauts return from nearly eight months on ISS after Starliner
problems
[[link removed]}&lead=419599&emailid=83844&nl=daily]
A SpaceX capsule carrying the crew parachuted before dawn on Friday
into the Gulf of Mexico, just off the Florida coast, after undocking
from the International Space Station earlier this week.
Work
Studies Show Emotional Intelligence Protects You Against 4 Bad
Leadership Behaviors
[[link removed]}&lead=419599&emailid=83844&nl=daily]
But there’s more. Emotional intelligence has long been recognized
as one of the most significant and impactful aspects
of great leadership. When working with other people, staying
emotionally open allows leaders to connect with their employees to
understand better and acknowledge how they feel. In team meetings, for
example, bringing emotional intelligence to the conversation creates
new levels of engagement, energy, and creative thinking.
Work
UnitedHealth says data of 100 million stolen in Change Healthcare
breach
[[link removed]}&lead=419599&emailid=83844&nl=daily]
UnitedHealth has confirmed for the first time that over 100 million
people had their personal information and healthcare data stolen in
the Change Healthcare ransomware attack, marking this as the largest
healthcare data breach in recent years.
Work
Brain waste-clearance system shown in people for first time
[[link removed]}&lead=419599&emailid=83844&nl=daily]
Though less well-known than the body’s blood vessels, the lymphatic
system is also vital to health. The network of lymphatic vessels
threaded throughout the body removes dead cells and other waste from
the bloodstream. It also helps transport the immune cells that fight
infections.
Work
The Lion of St. Marks Square in Venice is Chinese: Isotopic Analyses
Confirm It
[[link removed]}&lead=419599&emailid=83844&nl=daily]
The discovery comes from a multidisciplinary team of experts in
geology, chemistry, archaeology, and art history from the University
of Padua, the Ca’ Foscari University of Venice, and the
International Association for Mediterranean and Oriental Studies
(Ismeo). Through advanced metallurgical analysis, the team discovered
that a significant portion of the bronze used in the lion came from
the lower Yangtze River basin in southeastern China, and it was likely
cast during the Tang Dynasty (618-907 CE).
Work
BYD EV Teardown In Japan Reveals The Secret To Its Affordability
[[link removed]}&lead=419599&emailid=83844&nl=daily]
Japan used to be a world leader in electric and electrified vehicles
in the early 2000s, but its lead has since subsided, and it lags
behind most developed nations in this regard. China is the undisputed
global EV leader these days, and the Central Japan Economic and Trade
Bureau organized a seminar that involved the teardown of multiple EVs
to see how others are already so advanced.
Work
IBMs Red Hat Acquisition Will Pay For Itself By Early Next Year
[[link removed]}&lead=419599&emailid=83844&nl=daily]
Big Blue has reported its financial results for the third quarter of
2024, and the thing that stands out most is not the System z16
mainframes and Power10 midrange and big iron are getting a little long
in the tooth ahead of new product cycles expected to start in 2025.
Revenue slumps in these two core platforms from IBM are expected at
this point in the cycle, and in fact, both are holding up better than
past generations of systems did this late in the cycle.
Work
Georgia's election forces voters to choose between a future with
Russia or Europe
[[link removed]}&lead=419599&emailid=83844&nl=daily]
The vote on Saturday is being closely watched for whether the ruling
"Georgian Dream" party â which has morphed from an expressly
pro-Western grouping over its 12 years in power to a decidedly
pro-Russia one in recent years â can hold on to office, or whether it
will unseated by pro-Western opposition parties.
Work
Britain is a world leader in pet health care - The Economist
[[link removed]}&lead=419599&emailid=83844&nl=daily]
AN ONCOLOGY patient lies face down, surrounded by an expert team, as
they edge him into a state-of-the-art CT scanner. In the
intensive-care unit a ventilated patient lies under an inflatable
warming blanket, receiving one-to-one care from a specialist nurse;
watching on is an anaemia sufferer wearing an unseasonal Christmas
jumper. There is an emergency room but this afternoon it is empty,
says Vicky Lipscomb, a soft-tissue surgeon and the hospital’s
clinical director. Welcome to the Queen Mother Hospital for Animals
(QMHA) in Hertfordshire.
Work
Why Canada Is Scaling Back Its Immigration Ambitions - Bloomberg
[[link removed]}&lead=419599&emailid=83844&nl=daily]
A country that once embraced mass immigration to give it an edge in
the global race to replace aging workers is now pulling the welcome
mat away from newcomers.
Work
TSMCs Arizona Chip Production Yields Surpass Taiwans in Win for US
Push - Bloomberg [[link removed]}&lead=419599&emailid=83844&nl=daily]
Production yields in Arizona are 4 percentage points higher
Work
Wall Street Takes Tax-Loss Harvesting to the Next Level - Bloomberg
[[link removed]}&lead=419599&emailid=83844&nl=daily]
Money managers have a clever new tactic to cut taxes for rich clients.
Work
Partner pay at top US law firms jumps to record $1.4mn - FT
[[link removed]}&lead=419599&emailid=83844&nl=daily]
Survey shows 26% increase in two years on signs of revival in M&A
activity
Work
We should take awkwardness less personally, and more seriously | Aeon
Essays
[[link removed]}&lead=419599&emailid=83844&nl=daily]
A man knows he should speak up about the sexist behaviour of his
coworkers, but doesn’t, because they’re his friends and he
doesn’t want to make it awkward. A tenured professor is bothered by
her colleague’s flirtatious remarks, but says nothing, because it
would be awkward to bring it up. A person runs into a recently
bereaved coworker, and wonders whether to address their loss, but
doesn’t know what to say, so doesn’t mention it.
Work
Former Marseille, Morocco midfielder Barrada dies aged 35
[[link removed]}&lead=419599&emailid=83844&nl=daily]
Former Olympique de Marseille midfielder Abdelaziz Barrada has died at
the age of 35, the club said on Thursday, with the Moroccan federation
(FRMF) describing his death as a "great tragedy".
Work
Social Security worries hang over the incoming recipients
[[link removed]}&lead=419599&emailid=83844&nl=daily]
Voters polled by Newsweek believe that Democrats are better protectors
of Social Security than Republicans, even though the issue has barely
registered in the election battle between former President Donald
Trump and Vice President Kamala Harris.
Work
Your Vote Is Safe [[link removed]}&lead=419599&emailid=83844&nl=daily]
As Nov. 5 approaches, former president Donald Trump has left little
room for doubt about his intentions. He will almost certainly declare
victory on election night, as the votes are still being counted. He
may turn out to be right. But if Vice President Kamala Harris wins,
Trump will reject the result as corrupt and launch a scorched-earth
campaign to overturn it.
Work
Perplexity CEO Aravind Srinivas proposes revenue deals for publishers
- WSJ (No paywall) [[link removed]}&lead=419599&emailid=83844&nl=daily]
Perplexity wants to reach revenue-sharing partnerships with news
publishers that have criticized the AI-search startup for allegedly
misappropriating their content, its chief executive said Wednesday.
Work
Peter Schiff Warns Investors Against Keeping $20K In Cash: 'One Of The
Riskiest Bets You Can Make'
[[link removed]}&lead=419599&emailid=83844&nl=daily]
The global games market is projected to generate $272B by the end of
the year — for $0.55/share, this VC-backed startup with a 7M+
userbase gives investors easy access to this asset market.
Work
13 creator-economy startups to watch in 2024, according to top VCs -
Business Insider [[link removed]}&lead=419599&emailid=83844&nl=daily]
Platforms like YouTube, Instagram, and TikTok facilitate billions of
dollars flowing annually to influencers at a scale no startup is close
to matching. Meta and Google have the vast resources to launch and
test features quickly.
Work
Apples Have Never Tasted So Delicious. Heres Why - Scientific American
[[link removed]}&lead=419599&emailid=83844&nl=daily]
We are living in a golden age of apples, a time of delicious, diverse,
mouth-watering abundance that we could barely have imagined at the
turn of the millennium. How did we get to a time when most of us, most
of the year, can eat our choice of fragrant, juicy, sweet, crisp (oh
so crisp) apples?
Work
SpaceXs Crew-8 Returns NASA Astronauts To Earth After 7 Months -
Forbes [[link removed]}&lead=419599&emailid=83844&nl=daily]
SpaceXs Dragon spacecraft splashed down off the Florida coast Friday,
returning a crew of Russian and American astronauts who spent seven
months aboard the International Space Station following a series of
delays and issues with Boeings Starliner capsule.
Work
Voters prefer Trump, not just his policies - WSJ (No paywall)
[[link removed]}&lead=419599&emailid=83844&nl=daily]
No one can say precisely whether its due to hysterical Democrats
tossing unhinged insults at the Republican presidential nominee, anger
over the inflation of the Biden-Harris era, exhaustion with the
never-ending culture war against American tradition, or perhaps the
inability of the vice president to make a case for her candidacy. But
quite unexpectedly Donald Trump is becoming less controversial.
Work
Americans who want to do business in China need to meet this man - WSJ
(No paywall) [[link removed]}&lead=419599&emailid=83844&nl=daily]
When Janet Yellen traveled to Beijing earlier this year, there was one
person in particular she wanted to talk to: He Lifeng, one of the men
holding the keys to the Chinese economy.
Work
The US and IMF disagree about China. Thats a problem. - WSJ (No
paywall) [[link removed]}&lead=419599&emailid=83844&nl=daily]
Eighty years ago world leaders meeting in Bretton Woods, N.H., created
the International Monetary Fund to prevent the sorts of economic
imbalances that had brought on the Great Depression.
Work
Barack Obama Rallies for Kamala Harris, to the Chords of Bruce
Springsteen
[[link removed]}&lead=419599&emailid=83844&nl=daily]
She proceeded to attack former President Donald J. Trump as an
“unserious” yet dangerous authoritarian who would hurt Americans
in their everyday lives even as he undermined the nation’s
democracy.
Work
Harris Campaign Ads Use John Kelly's Words Describing Trump as
'Fascist'
[[link removed]}&lead=419599&emailid=83844&nl=daily]
Shane Goldmacher is a national political correspondent, covering the
2024 campaign and the major developments, trends and forces shaping
American politics. He can be reached at
[email protected].
More about Shane Goldmacher
Work
Poll Shows Dead Heat, and Biden to Apologize for Native American
School Abuses
[[link removed]}&lead=419599&emailid=83844&nl=daily]
Plus, a World Series with baseball’s biggest stars.
Work
What to Know About the Looming Election Certification Crisis
[[link removed]}&lead=419599&emailid=83844&nl=daily]
The post-2020 “voter integrity” movement has many leaders and
includes many groups, but among the most important is Cleta Mitchell,
who helped on Trump’s efforts to overturn his loss in Georgia.
Mitchell, though her Election Integrity Network, has exhorted allies
to get involved in elections at the state and the local level. “We
are going to retake our election system,” she said on her podcast,
“one county at a time all over America.”
Work
Wall Street has already priced in a Trump victory--just look at
European stocks and the inflation market
[[link removed]}&lead=419599&emailid=83844&nl=daily]
And because Wall Street expects Trump to win the election, projections
for the future rate of inflation have ticked up. For example,
inflation compensation, which is the premium investors are willing to
pay to protect the real value of their returns from inflation, rose
since September, according to Bank of America. Part of the increase
was due to positive economic data. Another part had to do with
Trump’s political fortunes.
Work
S&P 500 Poised for Weekly Drop After Yield Spike: Markets Wrap
[[link removed]}&lead=419599&emailid=83844&nl=daily]
(Bloomberg) -- S&P 500 futures were little changed, with the index
heading for its first weekly drop in seven as rising borrowing costs
put a chill on investor sentiment.Most Read from BloombergRobotaxis
Are No Friend of Public TransportationBooming Cambridge Exposes
England’s Widening Wealth GapOman Sees an Urban Future Distinct From
Dubai and Abu DhabiArgentina Drug Trafficking Hotspot Sees Murders
PlungeClimate Change Is Killing Buildings in Slow MotionThe US stocks
benchmark is set for an al
Work
Lost Silk Road Cities Discovered High in the Mountains of Central Asia
[[link removed]}&lead=419599&emailid=83844&nl=daily]
Hidden in the towering mountains of Central Asia, along what has been
called the Silk Road, archaeologists are uncovering two medieval
cities that may have bustled with inhabitants a thousand years ago.
Work
How Trump is a fascist became Kamalas closing argument
[[link removed]}&lead=419599&emailid=83844&nl=daily]
The US presidential campaign is in its final weeks and were dedicated
to helping you understand the stakes. In this election cycle, its more
important than ever to provide context beyond the headlines. But
in-depth reporting is costly, so to continue this vital work, we have
an ambitious goal to add 5,000 new members.
Work
The 'Greenest Governor' Fights to Save a Landmark Climate Law
[[link removed]}&lead=419599&emailid=83844&nl=daily]
The vote on the measure, Initiative 2117, is being watched across the
country and around the world as government leaders struggle with how
to put in place plans with enough potency to drastically alter carbon
emissions — the primary cause of global warming — while answering
to voters concerned about the costs.
Work
Harris and Trump Deadlocked to the End, Final Times/Siena National
Poll Finds
[[link removed]}&lead=419599&emailid=83844&nl=daily]
While this latest Times/Siena College poll offers a glimpse into
national sentiment, the presidential election will be decided in the
seven battleground states where Ms. Harris and Mr. Trump have devoted
the overwhelming amount of their time and resources. Most polls in
those states — Arizona, Georgia, Michigan, Nevada, North Carolina,
Pennsylvania, Wisconsin — suggest the contest is equally close.
TradeBriefs Publications are read by over 100,000 Industry Executives
About Us [[link removed]}&lead=419599&emailid=83844&nl=daily] | Advertise
[[link removed]}&lead=419599&emailid=83844&nl=daily] | Privacy Policy
[[link removed]}&lead=419599&emailid=83844&nl=daily]
Unsubscribe (one-click)
[[link removed]}&lead=419599&emailid=83844&nl=daily]
You are receiving this mail because of your subscription with
TradeBriefs.
Our mailing address is 3110 Thomas Ave, Dallas, TX 75204, USA