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** A Year of Action in 2023
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January 11, 2023

Dear Advocate,

At AVAC we saw tremendous work to accelerate HIV prevention and invest in global health resilience in 2022, and the year ahead will require critical advocacy to keep the field on track. What does this mean?

Our year-end letter, HIV Prevention and Equity in 2022 & Beyond ([link removed]) , explores in depth the many initiatives, resources and collaborations that powered advocacy in 2022 — a historic juncture for HIV and global health. The field is facing a turning point where the right commitments in funding, policy and programming in 2023 could put the world on track to hit 2025 targets, end HIV as a public health threat by 2030, and lay a solid foundation for global health security against future pandemics.

The world finds itself at this moment because of the convergence of the approval of two new biomedical options for HIV prevention— the ([link removed]) dapivirine vaginal ring ([link removed]) (DVR, or the ring) and injectable cabotegravir for PrEP ([link removed]) (CAB for PrEP)— with the launch of critical new strategies to advance HIV prevention from PEPFAR ([link removed]) , the Global Fund ([link removed]) , the Global HIV Prevention Coalition ([link removed]) , and The Coalition to Accelerate Access to Long-Acting PrEP ([link removed]) . All this in the context of a growing
consensus ([link removed]) and commitments to invest ([link removed]) in pandemic preparedness and strengthen health systems.

In 2023, advocacy must meet the moment. Here’s just a sample of what AVAC’s preparing for in the weeks and months ahead.

Access Access Access
* Accelerated planning and engagement with the Coalition to Accelerate Access to Long-Acting PrEP ([link removed]) and pushing key action steps for comprehensive and effective delivery of injectable CAB everywhere it’s needed.
* Taking action across our partnerships to establish the policies, budgets and programs that will deliver the ring to women who need it and want it.

Funding: Innovation and Expansion
* Defining a robust advocacy agenda for PEPFAR’s multi-year reauthorization starting in 2023.
* Supporting partners to help shape priorities for the Global Fund ([link removed]) , the Pandemic Fund ([link removed]) , PEPFAR country operational plans ([link removed]) (COPs).

The Research Pipeline
* Tracking the trials on injectable lenacapavir as PrEP ([link removed]) and t ([link removed]) he Dual Prevention Pill, ([link removed]) and engaging in the development of ([link removed]) next-generation ([link removed]) PrEP options ([link removed]) .
* Translating developments in research on HIV vaccines ([link removed]) and broadly neutralizing antibodies, ([link removed]) including possible results from the Mosaico vaccine trial, ([link removed]) the application of mRNA technology ([link removed]) and new approaches to research and trial design ([link removed]) .
* Advancinga research agenda for the prevention of other sexually transmitted infections (STIs), including greater investment in STI vaccine development. ([link removed])

People Centered Advocacy
* Advancing the reach of the GPP guidelines ([link removed]) by compiling a body of evidence on GPP’s value, impact, and best practices as a key resource for partners and for clinical research broadly.
* Watch-dogging the status of the HIV research agenda for: trans and gender diverse people, ([link removed]) pregnant and breastfeeding populations ([link removed]) , and other key populations.
* Engaging with new leadership at the National Institutes of Health and National Institutes of Allergy and Infectious Diseases to deepen collaboration with civil society, community and advocacy leadership.

Key Dates for January and February
Pull out your calendars for the first three months of 2023, these convenings will help shape your advocacy for the rest of the year.
* Jan 26: The Choice Agenda ([link removed]) webinar: Trans Inclusion: Charting HIV Research into the Future: A Manifesto and Scorecard for Advocates and Researchers, at 10 am. Register ([link removed])
* Feb 13: CROI is coming ([link removed]) ! Join The Choice Agenda and partners for the February 13 webinar ([link removed]) "Ready, Set, CROI 2023 - Prepare for the 30th Year of CROI".
* Stay tuned for the Margarita Breakfast Club series of three webinars highlighting the latest in science presented at CROI, open to all, held during the CROI conference, Feb 20 - 22.
* Feb 19-22: Whether or not you are attending CROI ([link removed]) , AVAC will have you covered as we track the research and the advocacy. Plus, we’ll have recordings from the Margarita Breakfast Club, for a curated discussion with CROI researchers.

Buckle up and lean in, let’s make 2023 an unforgettable year of collaboration and solutions.

Best,
AVAC

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