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IZ Express #1,669: CDC recommends updated COVID-19 vaccines for children younger than age 5 years, and more
| From | Immunize.org <[email protected]> |
| Subject | IZ Express #1,669: CDC recommends updated COVID-19 vaccines for children younger than age 5 years, and more |
| Date | December 14, 2022 11:00 AM |
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Issue 1,669: December 14, 2022
Top Stories
* CDC recommends updated (bivalent) COVID-19 vaccines for children younger than age 5 years
* Influenza activity is high across the nation; urge vaccination now
* Immunize.org updates its “Vaccines: Monkeypox (mpox)” web page
* “Reduced Risk for Mpox after Receipt of 1 or 2 Doses of JYNNEOS Vaccine Compared with Risk among Unvaccinated Persons—43 U.S. Jurisdictions, July 31–October 1, 2022” published in MMWR
* “Safety Monitoring of JYNNEOS Vaccine during the 2022 Mpox Outbreak—United States, May 22–October 21, 2022” published in MMWR
* Supplemental issue of the Journal of Infectious Diseases highlights “The Varicella Vaccination Program in the United States: 25 Years of Saving Lives and Preventing Illness”
* Spotlight: Immunize.org resources focused on communications between healthcare personnel, patients, and caregivers
* Vaccines in the news
Immunize.org Pages and Handouts
* Immunize.org updates informational handouts for parents on reliable sources of information and how to care for children after vaccinations
* Immunize.org updates "Vaccines with Diluents: How to Use Them"
* Immunize.org updates "Protect Yourself from Hepatitis A and Hepatitis B . . . A Guide for Gay and Bisexual Men"
* Immunize.org updates "Screening Checklist for Contraindications to Vaccines for Adults"
Vaccine Information Statements
* Immunize.org posts new Turkish translations of Dengue, Ebola, Rabies, and Smallpox/Monkeypox Vaccine Information Statements (#IZX13)
* Immunize.org posts 12 new and updated translations of Vaccine Information Statements for inactivated and live attenuated influenza vaccines (#IZX14)
Featured Resources
* Voices for Vaccines releases podcast on "Vaccine Sundays" and vaccine equity with Julissa Soto, MPH (#IZX15)
* Organizing a new vaccination program? Use Immunize.org’s Vaccinating Adults: A Step-by-Step Guide—free to download by chapter or in its entirety.
Notable Publications
* “Human Rabies—Texas, 2021” published in MMWR
Global News
* "Progress toward Poliomyelitis Eradication―Afghanistan, January 2021–September 2022" published in MMWR
Upcoming Events
* Virtual: NFID offers webinar “Plan Ahead: Vaccines Recommended for Travel” on December 15; CME available
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Top Stories
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CDC recommends updated (bivalent) COVID-19 vaccines for children younger than age 5 years
On December 9, CDC expanded its recommendations ([link removed]) for the updated (bivalent) Moderna and Pfizer-BioNTech COVID-19 vaccines to include children who begin the vaccination series as early as age 6 months. The updated (bivalent) dose is recommended as the third dose in the primary series for Pfizer vaccine recipients and as a booster (third) dose for recipients of the Moderna vaccine 2-dose primary series. This follows the FDA amendment to the emergency use authorizations ([link removed]) (EUAs) of the updated (bivalent) Moderna and Pfizer-BioNTech COVID-19 vaccines in this age group. A portion of the news release
([link removed]) appears below.
. . . CDC expanded the use of updated (bivalent) COVID-19 vaccines for children ages 6 months through 5 years. Children ages 6 months through 5 years who previously completed a Moderna primary series are eligible to receive a Moderna bivalent booster 2 months after their final primary series dose. Children ages 6 months through 4 years who are currently completing a Pfizer primary series will receive a Pfizer bivalent vaccine as their third primary dose.
The CDC web page, Use of COVID-19 Vaccines in the United States Interim Clinical Considerations ([link removed]) , now states:
* Children age 6 months–4 years who complete a Moderna primary series should receive one bivalent Moderna booster dose at least 2 months after completion of the primary series
* Children age 5 years who complete a Moderna primary series may receive either the previously authorized bivalent Pfizer-BioNTech booster dose or the newly authorized bivalent Moderna booster dose at least 2 months after completion of the Moderna primary series
* The previously authorized 3-dose Pfizer-BioNTech primary series for children age 6 months–4 years has been revised as follows: a monovalent Pfizer-BioNTech vaccine is administered for the first and second doses, followed by one bivalent Pfizer-BioNTech vaccine as the third primary series dose, at least 8 weeks after the second monovalent primary series dose. A booster dose is not authorized for children in this age group who receive a Pfizer-BioNTech 3-dose primary series, including children who previously received a 3-dose monovalent Pfizer-BioNTech primary series.
Healthcare professionals who administer these vaccines for children should review CDC’s interim clinical considerations for dose and other information.
Related Links
* CDC: Interim Clinical Considerations ([link removed]) main page summarizing use of COVID-19 vaccines in the United States
* CDC: CDC Expands Updated COVID-19 Vaccines to Include Children Ages 6 Months through 5 Years ([link removed]) (12/9/22)
* FDA: Coronavirus (COVID-19) Update: FDA Authorizes Updated (Bivalent) COVID-19 Vaccines for Children Down to 6 Months of Age ([link removed]) (12/8/22)
* FDA: COVID-19 Vaccines ([link removed]) main page
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Influenza activity is high across the nation; urge vaccination now
Urge your unprotected patients, coworkers, and loved ones to be vaccinated against influenza now, before they gather during the holidays. High levels of influenza activity are nationwide. CDC expects influenza activity to continue to increase in its seasonal epidemic pattern. CDC's Weekly U.S. Influenza Surveillance Report, FluView ([link removed]) , provides a valuable snapshot of influenza activity state-by-state.
Influenza Surveillance
For week 48, ending December 3, CDC's Weekly U.S. Influenza Surveillance Report, FluView ([link removed]) reports that, nationwide, 7.2% of patient visits reported through the Outpatient Influenza-Like Illness Surveillance Network (ILINet) were due to respiratory illness that included fever plus a cough or sore throat (i.e., influenza-like illness [ILI]). This exceeds the national baseline of 2.5%. Multiple respiratory viruses are co-circulating; the relative contribution of influenza virus infection to ILI varies by location. At this point, 21 children have already died from influenza-associated causes during the 2022–23 season.
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Influenza Vaccination Dashboard
CDC's Weekly Flu Vaccination Dashboard ([link removed]) data show that 155 million influenza vaccine doses were distributed in the United States through December 9, 2022. For all children, vaccination coverage for the week ending November 26, 2022, was similar to 1 year ago (42.5% compared with 40.9%) and 4.2 percentage points lower than same time 2 years ago (42.5% compared with 46.7%). Efforts are still needed to close the vaccination gap and protect more children.
CDC recommends everyone age 6 months and older get annual influenza vaccination. “Vaccines.gov” offers VaccineFinder ([link removed]) , a service of Boston Children’s Hospital, to help people find influenza and COVID-19 vaccines for any age group. To be listed as a provider by VaccineFinder, see the information at this website ([link removed]) .
Coadministration of influenza and COVID-19 bivalent booster vaccinations when both are due is safe, recommended, and efficient. COVID-19 vaccination alone provides no protection from influenza or any other respiratory virus. To gain confidence in your approach to administering multiple intramuscular vaccinations to an adult, download Immunize.org’s printable document How to Administer Multiple Intramuscular Vaccines to Adults during One Visit ([link removed]) .
[link removed]
Related Links
* CDC: Weekly National Flu Vaccination Dashboard ([link removed]) main page
* CDC: FluView ([link removed]) main page
* CDC: Influenza (Flu) ([link removed]) main page
* Immunize.org: free educational materials and patient handouts related to influenza ([link removed])
* Immunize.org: Vaccines: Influenza ([link removed]) main page
* Immunize.org: Ask the Experts: Influenza ([link removed]) main page
* Families Fighting Flu: Flu Resources for Healthcare Professionals ([link removed]) main page
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Immunize.org updates its “Vaccines: Monkeypox (mpox)” web page
Immunize.org updated its Vaccines: Monkeypox (mpox) ([link removed]) main page that provides links to key resource pages from CDC, FDA, Immunize.org, and other professional organizations. Revisions were made to:
[link removed]
* Incorporate WHO's prefered ([link removed].) name "mpox" as a synonym for monkeypox
* Add new materials under "Clinic Resources and Tools" for vaccine safety, training materials for providers, and administrative and operational issues
* Provide direct links to all sections of Interim Clinical Considerations for mpox vaccination
* Add information for clinical considerations for specific populations, including people who are pregnant or breastfeeding, people with HIV, and children and adolescents
* Add links to new educational materials from CDC, particularly on vaccine storage and handling
* Add links to CDC’s Visual Examples of Mpox Rash ([link removed]) (also in Spanish ([link removed]) )
Bookmark Immunize.org’s new Vaccines: Monkeypox (mpox) ([link removed]) main page for key links to important resources. The page will be updated as new guidelines and resources become available.
Related Links
* CDC: Mpox ([link removed]) main page
* CDC: Mpox: Vaccine Considerations ([link removed]) web page
* CDC: Video: How to Administer a Jynneos Vaccine Intradermally ([link removed])
* CDC: JYNNEOS Smallpox and Monkeypox Vaccine: Standing Orders for Administering Vaccine ([link removed]) (PDF)
* CDC: Jynneos Smallpox and Monkeypox Vaccine: Storage and Handling Summary ([link removed]) (PDF)
* Immunize.org: Vaccines: Monkeypox (mpox) ([link removed]) main page
* WHO: WHO Recommends New Name for Monkeypox Disease ([link removed].) (11/28/22)
Back to top (#Top)
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“Reduced Risk for Mpox after Receipt of 1 or 2 Doses of JYNNEOS Vaccine Compared with Risk among Unvaccinated Persons—43 U.S. Jurisdictions, July 31–October 1, 2022” published in MMWR
CDC published Reduced Risk for Mpox after Receipt of 1 or 2 Doses of JYNNEOS Vaccine Compared with Risk among Unvaccinated Persons—43 U.S. Jurisdictions, July 31–October 1, 2022 ([link removed]) on December 9 in MMWR. A portion of the summary appears below.
Real-world data on the magnitude and durability of protection by JYNNEOS vaccine against monkeypox (mpox) remain limited. . . .
Among JYNNEOS vaccine-eligible men aged 18–49 years in 43 U.S. jurisdictions, mpox incidence among unvaccinated persons was 9.6 times as high as that among persons who had received 2 vaccine doses and 7.4 times as high as that among persons who had received only the first dose. Preliminary evidence indicates no difference in protection between subcutaneous and intradermal administration routes. . . .
Although further study is needed to determine the magnitude and durability of protection, evidence indicates that JYNNEOS vaccination provides protection against mpox. Vaccine-eligible persons should complete the 2-dose vaccination series.
[link removed]
Access the MMWR article in HTML ([link removed]) or PDF ([link removed]) .
Related Link
* MMWR's main page ([link removed]) provides access to MMWR Weekly and its companion publications
Back to top (#Top)
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“Safety Monitoring of JYNNEOS Vaccine during the 2022 Mpox Outbreak—United States, May 22–October 21, 2022” published in MMWR
CDC published Safety Monitoring of JYNNEOS Vaccine during the 2022 Mpox Outbreak—United States, May 22–October 21, 2022 ([link removed]) on December 9 in MMWR. A portion of the summary appears below.
JYNNEOS vaccine has been used in a real-world setting for the first time during the 2022 monkeypox (mpox) outbreak, including intradermal administration under a Food and Drug Administration (FDA) Emergency Use Authorization. . . .
During May 22–October 21, 2022, nearly 1 million JYNNEOS doses were administered in the United States. The vaccine safety profile was consistent with prelicensure studies. The most common adverse health events reported were nonserious and included injection site reactions. Serious adverse events were rare among adults, and no serious adverse events have been identified among persons aged <18 years. . . .
Surveillance supports JYNNEOS vaccine safety. CDC and FDA will continue to monitor the safety of JYNNEOS.
Access the MMWR article in HTML ([link removed]) or PDF ([link removed]) .
Related Link
* MMWR's main page ([link removed]) provides access to MMWR Weekly and its companion publications
Back to top (#Top)
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Supplemental issue of the Journal of Infectious Diseases highlights “The Varicella Vaccination Program in the United States: 25 Years of Saving Lives and Preventing Illness”
On November 1, the Journal of Infectious Diseases published a supplement highlighting The Varicella Vaccination Program in the United States: 25 Years of Saving Lives and Preventing Illness ([link removed]) . The supplement includes 14 articles, many of which are available at no charge.
[link removed]
The lead article, 25 Years of Varicella Vaccination in the United States ([link removed]) , describes the health and economic impact of the varicella vaccination program. The United States was the first country to introduce varicella vaccine into the routine childhood vaccination program. Over the next 25 years, this program significantly reduced varicella disease burden. High vaccine coverage led to declines of more than 97% in varicella incidence and at least 90% in varicella-related hospitalizations and deaths The declines were greatest (99%) in people younger than 20 years of age born during the vaccination program, in whom varicella hospitalizations and deaths have been nearly eliminated in the United States.
Each year in the United States, varicella vaccination prevents more than an estimated 10,500 varicella hospitalizations and 100 deaths. The program achieved net societal savings of more than $23 billion dollars. This public health achievement was made possible by the efforts of thousands of nurses, physicians, pharmacists, and public health staff who implemented this vaccination program.
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Spotlight: Immunize.org resources focused on communications
Immunize.org offers many resources that focus on communication between healthcare personnel, patients, and caregivers
Talking about Vaccines ([link removed]) web page provides healthcare professionals with 11 topical web pages to help them discuss vaccination with concerned parents or patients. Topics include, for example, adjuvants, alternative medicine, autism, religious concerns, and thimerosal.
Unprotected People Stories ([link removed]) features more than 100 real-life accounts of people who suffered or died from vaccine-preventable diseases.
Handouts for Patients and Staff ([link removed]) leads to hundreds of resources that are free to download, print, copy, and distribute widely.
Vaccine Basics: Common Questions about Vaccines ([link removed]) on Immunize.org’s public website, vaccineinformation.org, offers patients and caregivers timely, accurate, and factual information about vaccines and the diseases they prevent.
Back to top (#Top)
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Vaccines in the news
These recent articles convey the potential risks of vaccine-preventable diseases and the importance of vaccination.
* CNN: Measles Outbreak in Central Ohio Grows to More than 50 Children, Driven by ‘Lack of Vaccination’ ([link removed]) (12/7/22)
* NBC: Myocarditis after COVID Vaccine Low among Teens and Young Adults, Large Study Finds ([link removed]) (12/5/22)
* CNN: Flu Vaccine Appears to Be a Very Good Match to Circulating Strains, CDC Says ([link removed]) (12/5/22)
* The Hill: Flu and COVID-19 Vaccine Uptake Remain Low ([link removed]) (12/2/22)
* NBC: Flu Hospitalization Rate Nearly Doubled during Thanksgiving Week, CDC Reports ([link removed]) (12/2/22)
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Immunize.org Pages and Handouts
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Immunize.org updates informational handouts for parents on reliable sources of information and how to care for children after vaccinations
Immunize.org updated its 1-page handout, Reliable Sources of Immunization Information: Where Parents Can Go to Find Answers! ([link removed]) , with information on new apps, books, and video suites, as well as a new footer and QR code linking users to the PDF of the current document.
[link removed]
Immunize.org also updated its 2-page handout, After the Shots...What to Do if Your Child Has Discomfort ([link removed]) , with space for listing recommended medication, dosage charts for acetaminophen and ibuprofen (page 2), a new footer, and QR code linking users to the PDF of the current document.
[link removed]
Related Links
* Immunize.org: Handouts: Parent Handouts ([link removed]) main page
* Immunize.org: Handouts for Patients and Staff ([link removed]) main page, where you can sort materials by topic, vaccine, or language
* Immunize.org: Educational Materials for Patients and Staff ([link removed]) —an alphabetical listing of more than 230 ready-to-print staff educational materials and patient handouts
Back to top (#Top)
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Immunize.org updates "Vaccines with Diluents: How to Use Them"
Immunize.org recently updated its 1-page resource, Vaccines with Diluents: How to Use Them ([link removed]) . Changes include the addition of Comirnaty (COVID-19), Dengvaxia (Dengue), and Vaxchora (cholera) vaccines, each of which is reconstituted with a diluent.
[link removed]
Related Links
* Immunize.org: Handouts: Storage and Handling ([link removed]) main page
* Immunize.org: Handouts ([link removed]) main page to see educational materials sorted by category
* Immunize.org: Educational Materials for Patients and Staff ([link removed]) —an alphabetical list of more than 230 ready-to-print staff educational materials and patient handouts
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Immunize.org updates "Protect Yourself from Hepatitis A and Hepatitis B . . . A Guide for Gay and Bisexual Men"
Immunize.org recently revised Protect Yourself from Hepatitis A and Hepatitis B . . . A Guide for Gay and Bisexual Men ([link removed]) . This 2-page information sheet now includes the routine recommendation for hepatitis B vaccination of all adults younger than 60, a new footer, and QR code linking users to the PDF of the current document.
[link removed]
Related Links
* Immunize.org: Vaccines: Hepatitis A ([link removed]) main page
* Immunize.org: Vaccines: Hepatitis B ([link removed]) main page
* Immunize.org: Handouts ([link removed]) main page to see educational materials sorted by category
* Immunize.org: Educational Materials for Patients and Staff ([link removed]) —an alphabetical list of more than 230 ready-to-print staff educational materials and patient handouts
Back to top (#Top)
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Immunize.org updates "Screening Checklist for Contraindications to Vaccines for Adults"
Immunize.org recently updated its 2-page Screening Checklist for Contraindications to Vaccines for Adults ([link removed]) with simplified patient questions, a new footer, and QR code linking users to the PDF of the current document.
[link removed]
Related Links
* Immunize.org: Handouts: Screening Checklists about Vaccine Contraindications and Precautions ([link removed]) main page
* Immunize.org: Handouts ([link removed]) main page to see educational materials sorted by category
* Immunize.org: Educational Materials for Patients and Staff ([link removed]) —an alphabetical list of more than 230 ready-to-print staff educational materials and patient handouts
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Vaccine Information Statements
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Immunize.org posts new Turkish translations of Dengue, Ebola, Rabies, and Smallpox/Monkeypox Vaccine Information Statements
Immunize.org posted new Turkish translations of Vaccine Information Statements ([link removed]) (VISs) generously donated by Betül Polatdemir, MD, Ankara, Turkey, and Nur Polatdemir Çevik, Near East University, Nicosia, Cyprus.
All translations are available in print-ready PDF format.
VIS translations in Turkish ([link removed]) :
* Dengue VIS PDF ([link removed]) (View in English ([link removed]) )
* Ebola VIS PDF ([link removed]) (View in English ([link removed]) )
* Rabies VIS PDF ([link removed]) (View in English ([link removed]) )
* Smallpox/Monkeypox VIS PDF ([link removed]) (View in English ([link removed]) )
Related Links
* Immunize.org: Vaccine Information Statement ([link removed]) main page for VISs in 47 languages ([link removed])
* Immunize.org: Dates of Current Vaccine Information Statements ([link removed]) (PDF)
* CDC: What's New with VISs ([link removed]) web page
* CDC: Current VISs ([link removed]) web page
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Immunize.org posts 12 new and updated translations of Vaccine Information Statements for inactivated and live attenuated influenza vaccines
Immunize.org posted new and updated translations of two influenza Vaccine Information Statements ([link removed]) (VISs), Influenza, Inactivated VIS ([link removed]) and Influenza, Live Intranasal VIS ([link removed]) .
All translations are available in print-ready PDF format.
Influenza, Inactivated VIS (view in English ([link removed]) ):
* Updated: German ([link removed])
* New: Italian ([link removed])
* Updated: Polish ([link removed])
* Updated: Swahili (Kiswahili) ([link removed])
* Updated: Urdu ([link removed])
* Updated: Yiddish ([link removed])
Influenza, Live Intranasal VIS (view in English ([link removed]) ):
* New: German ([link removed])
* New: Italian ([link removed])
* Updated: Polish ([link removed])
* New: Swahili (Kiswahili) ([link removed])
* Updated: Urdu ([link removed])
* Updated: Yiddish ([link removed])
Check the version dates of your office copies of newly updated translations. Translations of previous VIS versions should be discarded now that translations of the current versions have become available.
Related Links
* Immunize.org: Vaccine Information Statement ([link removed]) main page for VISs in 47 languages ([link removed])
* Immunize.org: Dates of Current Vaccine Information Statements ([link removed]) (PDF)
* CDC: What's New with VISs ([link removed]) web page
* CDC: Current VISs ([link removed]) web page
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Featured Resources
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Voices for Vaccines releases podcast on "Vaccine Sundays" and vaccine equity with Julissa Soto, MPH
Voices for Vaccines (VFV) posted a new entry in its Vax Talk podcast series: Vaccine Sundays and Equity ([link removed]) featuring Julissa Soto, MPH. A description from the VFV web page appears below.
Because vaccines work better when we are all vaccinated, vaccine equity isn’t about justice alone. It is also crucial to public health.
Enter Julissa Soto, MPH. Fresh off her work with other forms of health equity, she has come onto the scene in Colorado to make sure Latino communities can get vaccinated and feel confident doing so through her Vaccine Sundays program.
This episode is about so much more than that, though. Julissa is an inspiring woman whose life has been an amazing journey.
[link removed]
Related Links
* Voices for Vaccines: Resources ([link removed]) main page
* Voices for Vaccines podcast page ([link removed])
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Organizing a new vaccination program? Use Immunize.org’s Vaccinating Adults: A Step-by-Step Guide—free to download by chapter or in its entirety.
Download Immunize.org’s free 142-page book on adult vaccination to help build your program and train your team: Vaccinating Adults: A Step-by-Step Guide (Guide) ([link removed]) .
[link removed]
This thorough "how to" guide on adult vaccination provides easy-to-use, practical information covering all essential activities. It helps vaccine providers enhance their existing adult vaccination services or introduce them into any clinical setting.
The Guide is available to download/print either by chapter or in its entirety free at www.immunize.org/guide ([link removed]) . The National Vaccine Program Office and CDC both supported the development of the Guide and provided early technical review.
The Guide is a valuable resource to assist providers in increasing adult vaccination rates. Be sure to get a copy today!
Please note: this guide was produced in 2017, before the COVID-19 era, and reflects the recommendations of that time.
Related Links
* Vaccinating Adults: A Step-by-Step Guide ([link removed]) main page, permitting download of entire Guide (142 pages, PDF) ([link removed])
* View the table of contents and individual chapters (PDF):
+ Table of Contents ([link removed])
+ Step 1: Getting Started ([link removed])
+ Step 2: Setting Up for Vaccination Services ([link removed])
+ Step 3: Vaccine Storage and Handling ([link removed])
+ Step 4: Deciding Whom to Vaccinate ([link removed])
+ Step 5: Administering Vaccines ([link removed])
+ Step 6: Documentation and Related Issues ([link removed])
+ Step 7A: Financial Considerations ([link removed])
+ Step 7B: How to Bill for Adult Immunizations ([link removed])
* Immunize.org’s educational materials (handouts) on adult immunization ([link removed])
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Notable Publications
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“Human Rabies—Texas, 2021” published in MMWR
CDC published Human Rabies—Texas, 2021 ([link removed]) on December 9 in MMWR. A portion of the summary appears below.
U.S. human rabies deaths typically result from contact with rabid bats. Rabies is preventable when postexposure prophylaxis (PEP) is promptly administered; once clinical signs develop, the disease is nearly always fatal. . . .
A young boy was bitten by a bat; multiple persons knew of the exposure but did not recognize the rabies risk in the absence of a visible bite mark. Medical care was not sought until the child developed signs and symptoms 2 months later. One third of the child’s contacts met exposure criteria, and one quarter sought PEP; no secondary cases were detected. . . .
Enhanced public education about the risk for rabies associated with bat contact and the importance of seeking PEP if contact occurs is needed.
Access the MMWR article in HTML ([link removed]) or PDF ([link removed]) .
Related Link
* MMWR's main page ([link removed]) provides access to MMWR Weekly and its companion publications
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Global News
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"Progress toward Poliomyelitis Eradication―Afghanistan, January 2021–September 2022" published in MMWR
CDC published Progress toward Poliomyelitis Eradication―Afghanistan, January 2021–September 2022 ([link removed] ) on December 9 in MMWR. A portion of the summary appears below.
Afghanistan and Pakistan are the only countries where wild poliovirus type 1 (WPV1) remains endemic. . . .
Two WPV1 cases had been reported in 2022 as of September 30, compared with one case during the same period in 2021. No type 2 circulating vaccine-derived poliovirus was reported in 2022 compared with 43 cases in 2021. Since the political transition in August 2021, 3.5–4.5 million previously unreachable children were vaccinated; supplementary immunization activity (SIA) restrictions persist in the South Region. . . .
Ensuring implementation of high-quality SIAs in all parts of Afghanistan, especially in the high-risk provinces of the South Region, will accelerate progress toward interrupting WPV1 transmission.
Access the MMWR article in HTML ([link removed] ) or PDF ([link removed]) .
Related Link
* MMWR's main page ([link removed]) provides access to MMWR Weekly and its companion publications
Back to top (#Top)
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Upcoming Events
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Virtual: NFID offers webinar “Plan Ahead: Vaccines Recommended for Travel” on December 15; CME available
The National Foundation for Infectious Diseases (NFID) will host a webinar titled Plan Ahead: Vaccines Recommended for Travel ([link removed]) on December 15 from 2:00–3:00 p.m. (ET). Participants will learn about the geographic and clinical manifestations of certain pathogens encountered during travel, the current ACIP recommendations for common travel vaccines, and strategies for implementation of recommendations into clinical practice. NFID designates this enduring material for up to 1.0 AMA PRA Category 1 Credit.
Register for the webinar ([link removed]) .
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For more upcoming events, visit our Calendar of Events ([link removed]) .
Editorial Information
Editor-in-Chief
Kelly L. Moore, MD, MPH
Managing Editor
John D. Grabenstein, RPh, PhD
Associate Editor
Sharon G. Humiston, MD, MPH
Writer/Publication Coordinator
Taryn Chapman, MS
Courtnay Londo, MA
Style and Copy Editor
Marian Deegan, JD
Web Edition Managers
Arkady Shakhnovich
Jermaine Royes
Contributing Writer
Laurel H. Wood, MPA
Technical Reviewer
Kayla Ohlde
About IZ Express
Immunize.org welcomes redistribution of this issue of IZ Express or selected articles.
When you do so, please add a note that Immunize.org is the source of the material and provide a link to this issue ([link removed]) .
IZ Express is supported in part by Grant No. 1NH23IP922654 from the National Center for Immunization and Respiratory Diseases, CDC. Its contents are solely the responsibility of Immunize.org and do not necessarily represent the official views of CDC.
IZ Express Disclaimer ([link removed])
ISSN: 2771-8085
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Issue 1,669: December 14, 2022
Top Stories
* CDC recommends updated (bivalent) COVID-19 vaccines for children younger than age 5 years
* Influenza activity is high across the nation; urge vaccination now
* Immunize.org updates its “Vaccines: Monkeypox (mpox)” web page
* “Reduced Risk for Mpox after Receipt of 1 or 2 Doses of JYNNEOS Vaccine Compared with Risk among Unvaccinated Persons—43 U.S. Jurisdictions, July 31–October 1, 2022” published in MMWR
* “Safety Monitoring of JYNNEOS Vaccine during the 2022 Mpox Outbreak—United States, May 22–October 21, 2022” published in MMWR
* Supplemental issue of the Journal of Infectious Diseases highlights “The Varicella Vaccination Program in the United States: 25 Years of Saving Lives and Preventing Illness”
* Spotlight: Immunize.org resources focused on communications between healthcare personnel, patients, and caregivers
* Vaccines in the news
Immunize.org Pages and Handouts
* Immunize.org updates informational handouts for parents on reliable sources of information and how to care for children after vaccinations
* Immunize.org updates "Vaccines with Diluents: How to Use Them"
* Immunize.org updates "Protect Yourself from Hepatitis A and Hepatitis B . . . A Guide for Gay and Bisexual Men"
* Immunize.org updates "Screening Checklist for Contraindications to Vaccines for Adults"
Vaccine Information Statements
* Immunize.org posts new Turkish translations of Dengue, Ebola, Rabies, and Smallpox/Monkeypox Vaccine Information Statements (#IZX13)
* Immunize.org posts 12 new and updated translations of Vaccine Information Statements for inactivated and live attenuated influenza vaccines (#IZX14)
Featured Resources
* Voices for Vaccines releases podcast on "Vaccine Sundays" and vaccine equity with Julissa Soto, MPH (#IZX15)
* Organizing a new vaccination program? Use Immunize.org’s Vaccinating Adults: A Step-by-Step Guide—free to download by chapter or in its entirety.
Notable Publications
* “Human Rabies—Texas, 2021” published in MMWR
Global News
* "Progress toward Poliomyelitis Eradication―Afghanistan, January 2021–September 2022" published in MMWR
Upcoming Events
* Virtual: NFID offers webinar “Plan Ahead: Vaccines Recommended for Travel” on December 15; CME available
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Top Stories
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CDC recommends updated (bivalent) COVID-19 vaccines for children younger than age 5 years
On December 9, CDC expanded its recommendations ([link removed]) for the updated (bivalent) Moderna and Pfizer-BioNTech COVID-19 vaccines to include children who begin the vaccination series as early as age 6 months. The updated (bivalent) dose is recommended as the third dose in the primary series for Pfizer vaccine recipients and as a booster (third) dose for recipients of the Moderna vaccine 2-dose primary series. This follows the FDA amendment to the emergency use authorizations ([link removed]) (EUAs) of the updated (bivalent) Moderna and Pfizer-BioNTech COVID-19 vaccines in this age group. A portion of the news release
([link removed]) appears below.
. . . CDC expanded the use of updated (bivalent) COVID-19 vaccines for children ages 6 months through 5 years. Children ages 6 months through 5 years who previously completed a Moderna primary series are eligible to receive a Moderna bivalent booster 2 months after their final primary series dose. Children ages 6 months through 4 years who are currently completing a Pfizer primary series will receive a Pfizer bivalent vaccine as their third primary dose.
The CDC web page, Use of COVID-19 Vaccines in the United States Interim Clinical Considerations ([link removed]) , now states:
* Children age 6 months–4 years who complete a Moderna primary series should receive one bivalent Moderna booster dose at least 2 months after completion of the primary series
* Children age 5 years who complete a Moderna primary series may receive either the previously authorized bivalent Pfizer-BioNTech booster dose or the newly authorized bivalent Moderna booster dose at least 2 months after completion of the Moderna primary series
* The previously authorized 3-dose Pfizer-BioNTech primary series for children age 6 months–4 years has been revised as follows: a monovalent Pfizer-BioNTech vaccine is administered for the first and second doses, followed by one bivalent Pfizer-BioNTech vaccine as the third primary series dose, at least 8 weeks after the second monovalent primary series dose. A booster dose is not authorized for children in this age group who receive a Pfizer-BioNTech 3-dose primary series, including children who previously received a 3-dose monovalent Pfizer-BioNTech primary series.
Healthcare professionals who administer these vaccines for children should review CDC’s interim clinical considerations for dose and other information.
Related Links
* CDC: Interim Clinical Considerations ([link removed]) main page summarizing use of COVID-19 vaccines in the United States
* CDC: CDC Expands Updated COVID-19 Vaccines to Include Children Ages 6 Months through 5 Years ([link removed]) (12/9/22)
* FDA: Coronavirus (COVID-19) Update: FDA Authorizes Updated (Bivalent) COVID-19 Vaccines for Children Down to 6 Months of Age ([link removed]) (12/8/22)
* FDA: COVID-19 Vaccines ([link removed]) main page
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Influenza activity is high across the nation; urge vaccination now
Urge your unprotected patients, coworkers, and loved ones to be vaccinated against influenza now, before they gather during the holidays. High levels of influenza activity are nationwide. CDC expects influenza activity to continue to increase in its seasonal epidemic pattern. CDC's Weekly U.S. Influenza Surveillance Report, FluView ([link removed]) , provides a valuable snapshot of influenza activity state-by-state.
Influenza Surveillance
For week 48, ending December 3, CDC's Weekly U.S. Influenza Surveillance Report, FluView ([link removed]) reports that, nationwide, 7.2% of patient visits reported through the Outpatient Influenza-Like Illness Surveillance Network (ILINet) were due to respiratory illness that included fever plus a cough or sore throat (i.e., influenza-like illness [ILI]). This exceeds the national baseline of 2.5%. Multiple respiratory viruses are co-circulating; the relative contribution of influenza virus infection to ILI varies by location. At this point, 21 children have already died from influenza-associated causes during the 2022–23 season.
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Influenza Vaccination Dashboard
CDC's Weekly Flu Vaccination Dashboard ([link removed]) data show that 155 million influenza vaccine doses were distributed in the United States through December 9, 2022. For all children, vaccination coverage for the week ending November 26, 2022, was similar to 1 year ago (42.5% compared with 40.9%) and 4.2 percentage points lower than same time 2 years ago (42.5% compared with 46.7%). Efforts are still needed to close the vaccination gap and protect more children.
CDC recommends everyone age 6 months and older get annual influenza vaccination. “Vaccines.gov” offers VaccineFinder ([link removed]) , a service of Boston Children’s Hospital, to help people find influenza and COVID-19 vaccines for any age group. To be listed as a provider by VaccineFinder, see the information at this website ([link removed]) .
Coadministration of influenza and COVID-19 bivalent booster vaccinations when both are due is safe, recommended, and efficient. COVID-19 vaccination alone provides no protection from influenza or any other respiratory virus. To gain confidence in your approach to administering multiple intramuscular vaccinations to an adult, download Immunize.org’s printable document How to Administer Multiple Intramuscular Vaccines to Adults during One Visit ([link removed]) .
[link removed]
Related Links
* CDC: Weekly National Flu Vaccination Dashboard ([link removed]) main page
* CDC: FluView ([link removed]) main page
* CDC: Influenza (Flu) ([link removed]) main page
* Immunize.org: free educational materials and patient handouts related to influenza ([link removed])
* Immunize.org: Vaccines: Influenza ([link removed]) main page
* Immunize.org: Ask the Experts: Influenza ([link removed]) main page
* Families Fighting Flu: Flu Resources for Healthcare Professionals ([link removed]) main page
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Immunize.org updates its “Vaccines: Monkeypox (mpox)” web page
Immunize.org updated its Vaccines: Monkeypox (mpox) ([link removed]) main page that provides links to key resource pages from CDC, FDA, Immunize.org, and other professional organizations. Revisions were made to:
[link removed]
* Incorporate WHO's prefered ([link removed].) name "mpox" as a synonym for monkeypox
* Add new materials under "Clinic Resources and Tools" for vaccine safety, training materials for providers, and administrative and operational issues
* Provide direct links to all sections of Interim Clinical Considerations for mpox vaccination
* Add information for clinical considerations for specific populations, including people who are pregnant or breastfeeding, people with HIV, and children and adolescents
* Add links to new educational materials from CDC, particularly on vaccine storage and handling
* Add links to CDC’s Visual Examples of Mpox Rash ([link removed]) (also in Spanish ([link removed]) )
Bookmark Immunize.org’s new Vaccines: Monkeypox (mpox) ([link removed]) main page for key links to important resources. The page will be updated as new guidelines and resources become available.
Related Links
* CDC: Mpox ([link removed]) main page
* CDC: Mpox: Vaccine Considerations ([link removed]) web page
* CDC: Video: How to Administer a Jynneos Vaccine Intradermally ([link removed])
* CDC: JYNNEOS Smallpox and Monkeypox Vaccine: Standing Orders for Administering Vaccine ([link removed]) (PDF)
* CDC: Jynneos Smallpox and Monkeypox Vaccine: Storage and Handling Summary ([link removed]) (PDF)
* Immunize.org: Vaccines: Monkeypox (mpox) ([link removed]) main page
* WHO: WHO Recommends New Name for Monkeypox Disease ([link removed].) (11/28/22)
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“Reduced Risk for Mpox after Receipt of 1 or 2 Doses of JYNNEOS Vaccine Compared with Risk among Unvaccinated Persons—43 U.S. Jurisdictions, July 31–October 1, 2022” published in MMWR
CDC published Reduced Risk for Mpox after Receipt of 1 or 2 Doses of JYNNEOS Vaccine Compared with Risk among Unvaccinated Persons—43 U.S. Jurisdictions, July 31–October 1, 2022 ([link removed]) on December 9 in MMWR. A portion of the summary appears below.
Real-world data on the magnitude and durability of protection by JYNNEOS vaccine against monkeypox (mpox) remain limited. . . .
Among JYNNEOS vaccine-eligible men aged 18–49 years in 43 U.S. jurisdictions, mpox incidence among unvaccinated persons was 9.6 times as high as that among persons who had received 2 vaccine doses and 7.4 times as high as that among persons who had received only the first dose. Preliminary evidence indicates no difference in protection between subcutaneous and intradermal administration routes. . . .
Although further study is needed to determine the magnitude and durability of protection, evidence indicates that JYNNEOS vaccination provides protection against mpox. Vaccine-eligible persons should complete the 2-dose vaccination series.
[link removed]
Access the MMWR article in HTML ([link removed]) or PDF ([link removed]) .
Related Link
* MMWR's main page ([link removed]) provides access to MMWR Weekly and its companion publications
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“Safety Monitoring of JYNNEOS Vaccine during the 2022 Mpox Outbreak—United States, May 22–October 21, 2022” published in MMWR
CDC published Safety Monitoring of JYNNEOS Vaccine during the 2022 Mpox Outbreak—United States, May 22–October 21, 2022 ([link removed]) on December 9 in MMWR. A portion of the summary appears below.
JYNNEOS vaccine has been used in a real-world setting for the first time during the 2022 monkeypox (mpox) outbreak, including intradermal administration under a Food and Drug Administration (FDA) Emergency Use Authorization. . . .
During May 22–October 21, 2022, nearly 1 million JYNNEOS doses were administered in the United States. The vaccine safety profile was consistent with prelicensure studies. The most common adverse health events reported were nonserious and included injection site reactions. Serious adverse events were rare among adults, and no serious adverse events have been identified among persons aged <18 years. . . .
Surveillance supports JYNNEOS vaccine safety. CDC and FDA will continue to monitor the safety of JYNNEOS.
Access the MMWR article in HTML ([link removed]) or PDF ([link removed]) .
Related Link
* MMWR's main page ([link removed]) provides access to MMWR Weekly and its companion publications
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Supplemental issue of the Journal of Infectious Diseases highlights “The Varicella Vaccination Program in the United States: 25 Years of Saving Lives and Preventing Illness”
On November 1, the Journal of Infectious Diseases published a supplement highlighting The Varicella Vaccination Program in the United States: 25 Years of Saving Lives and Preventing Illness ([link removed]) . The supplement includes 14 articles, many of which are available at no charge.
[link removed]
The lead article, 25 Years of Varicella Vaccination in the United States ([link removed]) , describes the health and economic impact of the varicella vaccination program. The United States was the first country to introduce varicella vaccine into the routine childhood vaccination program. Over the next 25 years, this program significantly reduced varicella disease burden. High vaccine coverage led to declines of more than 97% in varicella incidence and at least 90% in varicella-related hospitalizations and deaths The declines were greatest (99%) in people younger than 20 years of age born during the vaccination program, in whom varicella hospitalizations and deaths have been nearly eliminated in the United States.
Each year in the United States, varicella vaccination prevents more than an estimated 10,500 varicella hospitalizations and 100 deaths. The program achieved net societal savings of more than $23 billion dollars. This public health achievement was made possible by the efforts of thousands of nurses, physicians, pharmacists, and public health staff who implemented this vaccination program.
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Spotlight: Immunize.org resources focused on communications
Immunize.org offers many resources that focus on communication between healthcare personnel, patients, and caregivers
Talking about Vaccines ([link removed]) web page provides healthcare professionals with 11 topical web pages to help them discuss vaccination with concerned parents or patients. Topics include, for example, adjuvants, alternative medicine, autism, religious concerns, and thimerosal.
Unprotected People Stories ([link removed]) features more than 100 real-life accounts of people who suffered or died from vaccine-preventable diseases.
Handouts for Patients and Staff ([link removed]) leads to hundreds of resources that are free to download, print, copy, and distribute widely.
Vaccine Basics: Common Questions about Vaccines ([link removed]) on Immunize.org’s public website, vaccineinformation.org, offers patients and caregivers timely, accurate, and factual information about vaccines and the diseases they prevent.
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Vaccines in the news
These recent articles convey the potential risks of vaccine-preventable diseases and the importance of vaccination.
* CNN: Measles Outbreak in Central Ohio Grows to More than 50 Children, Driven by ‘Lack of Vaccination’ ([link removed]) (12/7/22)
* NBC: Myocarditis after COVID Vaccine Low among Teens and Young Adults, Large Study Finds ([link removed]) (12/5/22)
* CNN: Flu Vaccine Appears to Be a Very Good Match to Circulating Strains, CDC Says ([link removed]) (12/5/22)
* The Hill: Flu and COVID-19 Vaccine Uptake Remain Low ([link removed]) (12/2/22)
* NBC: Flu Hospitalization Rate Nearly Doubled during Thanksgiving Week, CDC Reports ([link removed]) (12/2/22)
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Immunize.org Pages and Handouts
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Immunize.org updates informational handouts for parents on reliable sources of information and how to care for children after vaccinations
Immunize.org updated its 1-page handout, Reliable Sources of Immunization Information: Where Parents Can Go to Find Answers! ([link removed]) , with information on new apps, books, and video suites, as well as a new footer and QR code linking users to the PDF of the current document.
[link removed]
Immunize.org also updated its 2-page handout, After the Shots...What to Do if Your Child Has Discomfort ([link removed]) , with space for listing recommended medication, dosage charts for acetaminophen and ibuprofen (page 2), a new footer, and QR code linking users to the PDF of the current document.
[link removed]
Related Links
* Immunize.org: Handouts: Parent Handouts ([link removed]) main page
* Immunize.org: Handouts for Patients and Staff ([link removed]) main page, where you can sort materials by topic, vaccine, or language
* Immunize.org: Educational Materials for Patients and Staff ([link removed]) —an alphabetical listing of more than 230 ready-to-print staff educational materials and patient handouts
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Immunize.org updates "Vaccines with Diluents: How to Use Them"
Immunize.org recently updated its 1-page resource, Vaccines with Diluents: How to Use Them ([link removed]) . Changes include the addition of Comirnaty (COVID-19), Dengvaxia (Dengue), and Vaxchora (cholera) vaccines, each of which is reconstituted with a diluent.
[link removed]
Related Links
* Immunize.org: Handouts: Storage and Handling ([link removed]) main page
* Immunize.org: Handouts ([link removed]) main page to see educational materials sorted by category
* Immunize.org: Educational Materials for Patients and Staff ([link removed]) —an alphabetical list of more than 230 ready-to-print staff educational materials and patient handouts
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Immunize.org updates "Protect Yourself from Hepatitis A and Hepatitis B . . . A Guide for Gay and Bisexual Men"
Immunize.org recently revised Protect Yourself from Hepatitis A and Hepatitis B . . . A Guide for Gay and Bisexual Men ([link removed]) . This 2-page information sheet now includes the routine recommendation for hepatitis B vaccination of all adults younger than 60, a new footer, and QR code linking users to the PDF of the current document.
[link removed]
Related Links
* Immunize.org: Vaccines: Hepatitis A ([link removed]) main page
* Immunize.org: Vaccines: Hepatitis B ([link removed]) main page
* Immunize.org: Handouts ([link removed]) main page to see educational materials sorted by category
* Immunize.org: Educational Materials for Patients and Staff ([link removed]) —an alphabetical list of more than 230 ready-to-print staff educational materials and patient handouts
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Immunize.org updates "Screening Checklist for Contraindications to Vaccines for Adults"
Immunize.org recently updated its 2-page Screening Checklist for Contraindications to Vaccines for Adults ([link removed]) with simplified patient questions, a new footer, and QR code linking users to the PDF of the current document.
[link removed]
Related Links
* Immunize.org: Handouts: Screening Checklists about Vaccine Contraindications and Precautions ([link removed]) main page
* Immunize.org: Handouts ([link removed]) main page to see educational materials sorted by category
* Immunize.org: Educational Materials for Patients and Staff ([link removed]) —an alphabetical list of more than 230 ready-to-print staff educational materials and patient handouts
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Vaccine Information Statements
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Immunize.org posts new Turkish translations of Dengue, Ebola, Rabies, and Smallpox/Monkeypox Vaccine Information Statements
Immunize.org posted new Turkish translations of Vaccine Information Statements ([link removed]) (VISs) generously donated by Betül Polatdemir, MD, Ankara, Turkey, and Nur Polatdemir Çevik, Near East University, Nicosia, Cyprus.
All translations are available in print-ready PDF format.
VIS translations in Turkish ([link removed]) :
* Dengue VIS PDF ([link removed]) (View in English ([link removed]) )
* Ebola VIS PDF ([link removed]) (View in English ([link removed]) )
* Rabies VIS PDF ([link removed]) (View in English ([link removed]) )
* Smallpox/Monkeypox VIS PDF ([link removed]) (View in English ([link removed]) )
Related Links
* Immunize.org: Vaccine Information Statement ([link removed]) main page for VISs in 47 languages ([link removed])
* Immunize.org: Dates of Current Vaccine Information Statements ([link removed]) (PDF)
* CDC: What's New with VISs ([link removed]) web page
* CDC: Current VISs ([link removed]) web page
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Immunize.org posts 12 new and updated translations of Vaccine Information Statements for inactivated and live attenuated influenza vaccines
Immunize.org posted new and updated translations of two influenza Vaccine Information Statements ([link removed]) (VISs), Influenza, Inactivated VIS ([link removed]) and Influenza, Live Intranasal VIS ([link removed]) .
All translations are available in print-ready PDF format.
Influenza, Inactivated VIS (view in English ([link removed]) ):
* Updated: German ([link removed])
* New: Italian ([link removed])
* Updated: Polish ([link removed])
* Updated: Swahili (Kiswahili) ([link removed])
* Updated: Urdu ([link removed])
* Updated: Yiddish ([link removed])
Influenza, Live Intranasal VIS (view in English ([link removed]) ):
* New: German ([link removed])
* New: Italian ([link removed])
* Updated: Polish ([link removed])
* New: Swahili (Kiswahili) ([link removed])
* Updated: Urdu ([link removed])
* Updated: Yiddish ([link removed])
Check the version dates of your office copies of newly updated translations. Translations of previous VIS versions should be discarded now that translations of the current versions have become available.
Related Links
* Immunize.org: Vaccine Information Statement ([link removed]) main page for VISs in 47 languages ([link removed])
* Immunize.org: Dates of Current Vaccine Information Statements ([link removed]) (PDF)
* CDC: What's New with VISs ([link removed]) web page
* CDC: Current VISs ([link removed]) web page
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Featured Resources
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Voices for Vaccines releases podcast on "Vaccine Sundays" and vaccine equity with Julissa Soto, MPH
Voices for Vaccines (VFV) posted a new entry in its Vax Talk podcast series: Vaccine Sundays and Equity ([link removed]) featuring Julissa Soto, MPH. A description from the VFV web page appears below.
Because vaccines work better when we are all vaccinated, vaccine equity isn’t about justice alone. It is also crucial to public health.
Enter Julissa Soto, MPH. Fresh off her work with other forms of health equity, she has come onto the scene in Colorado to make sure Latino communities can get vaccinated and feel confident doing so through her Vaccine Sundays program.
This episode is about so much more than that, though. Julissa is an inspiring woman whose life has been an amazing journey.
[link removed]
Related Links
* Voices for Vaccines: Resources ([link removed]) main page
* Voices for Vaccines podcast page ([link removed])
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Organizing a new vaccination program? Use Immunize.org’s Vaccinating Adults: A Step-by-Step Guide—free to download by chapter or in its entirety.
Download Immunize.org’s free 142-page book on adult vaccination to help build your program and train your team: Vaccinating Adults: A Step-by-Step Guide (Guide) ([link removed]) .
[link removed]
This thorough "how to" guide on adult vaccination provides easy-to-use, practical information covering all essential activities. It helps vaccine providers enhance their existing adult vaccination services or introduce them into any clinical setting.
The Guide is available to download/print either by chapter or in its entirety free at www.immunize.org/guide ([link removed]) . The National Vaccine Program Office and CDC both supported the development of the Guide and provided early technical review.
The Guide is a valuable resource to assist providers in increasing adult vaccination rates. Be sure to get a copy today!
Please note: this guide was produced in 2017, before the COVID-19 era, and reflects the recommendations of that time.
Related Links
* Vaccinating Adults: A Step-by-Step Guide ([link removed]) main page, permitting download of entire Guide (142 pages, PDF) ([link removed])
* View the table of contents and individual chapters (PDF):
+ Table of Contents ([link removed])
+ Step 1: Getting Started ([link removed])
+ Step 2: Setting Up for Vaccination Services ([link removed])
+ Step 3: Vaccine Storage and Handling ([link removed])
+ Step 4: Deciding Whom to Vaccinate ([link removed])
+ Step 5: Administering Vaccines ([link removed])
+ Step 6: Documentation and Related Issues ([link removed])
+ Step 7A: Financial Considerations ([link removed])
+ Step 7B: How to Bill for Adult Immunizations ([link removed])
* Immunize.org’s educational materials (handouts) on adult immunization ([link removed])
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Notable Publications
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“Human Rabies—Texas, 2021” published in MMWR
CDC published Human Rabies—Texas, 2021 ([link removed]) on December 9 in MMWR. A portion of the summary appears below.
U.S. human rabies deaths typically result from contact with rabid bats. Rabies is preventable when postexposure prophylaxis (PEP) is promptly administered; once clinical signs develop, the disease is nearly always fatal. . . .
A young boy was bitten by a bat; multiple persons knew of the exposure but did not recognize the rabies risk in the absence of a visible bite mark. Medical care was not sought until the child developed signs and symptoms 2 months later. One third of the child’s contacts met exposure criteria, and one quarter sought PEP; no secondary cases were detected. . . .
Enhanced public education about the risk for rabies associated with bat contact and the importance of seeking PEP if contact occurs is needed.
Access the MMWR article in HTML ([link removed]) or PDF ([link removed]) .
Related Link
* MMWR's main page ([link removed]) provides access to MMWR Weekly and its companion publications
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Global News
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"Progress toward Poliomyelitis Eradication―Afghanistan, January 2021–September 2022" published in MMWR
CDC published Progress toward Poliomyelitis Eradication―Afghanistan, January 2021–September 2022 ([link removed] ) on December 9 in MMWR. A portion of the summary appears below.
Afghanistan and Pakistan are the only countries where wild poliovirus type 1 (WPV1) remains endemic. . . .
Two WPV1 cases had been reported in 2022 as of September 30, compared with one case during the same period in 2021. No type 2 circulating vaccine-derived poliovirus was reported in 2022 compared with 43 cases in 2021. Since the political transition in August 2021, 3.5–4.5 million previously unreachable children were vaccinated; supplementary immunization activity (SIA) restrictions persist in the South Region. . . .
Ensuring implementation of high-quality SIAs in all parts of Afghanistan, especially in the high-risk provinces of the South Region, will accelerate progress toward interrupting WPV1 transmission.
Access the MMWR article in HTML ([link removed] ) or PDF ([link removed]) .
Related Link
* MMWR's main page ([link removed]) provides access to MMWR Weekly and its companion publications
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Upcoming Events
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Virtual: NFID offers webinar “Plan Ahead: Vaccines Recommended for Travel” on December 15; CME available
The National Foundation for Infectious Diseases (NFID) will host a webinar titled Plan Ahead: Vaccines Recommended for Travel ([link removed]) on December 15 from 2:00–3:00 p.m. (ET). Participants will learn about the geographic and clinical manifestations of certain pathogens encountered during travel, the current ACIP recommendations for common travel vaccines, and strategies for implementation of recommendations into clinical practice. NFID designates this enduring material for up to 1.0 AMA PRA Category 1 Credit.
Register for the webinar ([link removed]) .
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For more upcoming events, visit our Calendar of Events ([link removed]) .
Editorial Information
Editor-in-Chief
Kelly L. Moore, MD, MPH
Managing Editor
John D. Grabenstein, RPh, PhD
Associate Editor
Sharon G. Humiston, MD, MPH
Writer/Publication Coordinator
Taryn Chapman, MS
Courtnay Londo, MA
Style and Copy Editor
Marian Deegan, JD
Web Edition Managers
Arkady Shakhnovich
Jermaine Royes
Contributing Writer
Laurel H. Wood, MPA
Technical Reviewer
Kayla Ohlde
About IZ Express
Immunize.org welcomes redistribution of this issue of IZ Express or selected articles.
When you do so, please add a note that Immunize.org is the source of the material and provide a link to this issue ([link removed]) .
IZ Express is supported in part by Grant No. 1NH23IP922654 from the National Center for Immunization and Respiratory Diseases, CDC. Its contents are solely the responsibility of Immunize.org and do not necessarily represent the official views of CDC.
IZ Express Disclaimer ([link removed])
ISSN: 2771-8085
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