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IZ Express #1,663: Current ACIP recs for bivalent COVID-19 boosters published in MMWR, and more
| From | Immunize.org <[email protected]> |
| Subject | IZ Express #1,663: Current ACIP recs for bivalent COVID-19 boosters published in MMWR, and more |
| Date | November 16, 2022 11:00 AM |
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Issue 1,663: November 16, 2022
Top Stories
* “Interim Recommendations from the Advisory Committee on Immunization Practices for the Use of Bivalent Booster Doses of COVID-19 Vaccines—United States, 2022” published in MMWR describing ACIP votes on September 1 and October 12, 2022
* Influenza continues its march; step up the vaccine defenses
* Immunize.org remembers our friend and vaccine pioneer Samuel L. Katz, MD (1927–2022)
* National Community Pharmacists Association releases first episode of "Show Me," an online reality series following pharmacists as they start or improve vaccination programs
* No mixing, no diluting: FDA licenses new Rotarix liquid formulation
* Immunize.org's Influenza Vaccination Honor Roll for mandatory healthcare worker vaccination now features 1,294 organizations, including one new facility
* Spotlight: Immunize.org's "Handouts" main page provides free access to hundreds of vaccination-related handouts and fact sheets
* Vaccines in the news
Immunize.org Pages and Handouts
* Immunize.org updates two standing orders templates for administering hepatitis A vaccine—one for children and teens and one for adults
Featured Resources
* Voices for Vaccines releases podcast on mRNA vaccines and what the future may hold
* Organizing a new vaccination program? Use Immunize.org’s Vaccinating Adults: A Step-by-Step Guide—free to download by chapter or in its entirety.
Notable Publications
* “Preferential Recommendations for Vaccines: Time for a Structured, Transparent Process” commentary published online in Vaccine
* “COVID-19–Associated Hospitalizations among U.S. Infants Aged <6 Months—COVID-NET, 13 States, June 2021–August 2022” published in MMWR
* “Epidemiologic Features of the Monkeypox Outbreak and the Public Health Response—United States, May 17–October 6, 2022” published in MMWR
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Top Stories
------------------------------------------------------------
“Interim Recommendations from the Advisory Committee on Immunization Practices for the Use of Bivalent Booster Doses of COVID-19 Vaccines—United States, 2022” published in MMWR describing ACIP votes on September 1 and October 12, 2022
CDC published Interim Recommendations from the Advisory Committee on Immunization Practices for the Use of Bivalent Booster Doses of COVID-19 Vaccines—United States, 2022 ([link removed]) ([link removed]) on November 11 in MMWR. The recommendations described were approved by ACIP on September 1 and October 12. A portion of the summary appears below.
In the United States, COVID-19 monovalent booster vaccination was previously recommended, but related protection decreased after the emergence of Omicron subvariants. . . .
In fall 2022, CDC recommended a bivalent mRNA COVID-19 vaccine booster dose for persons aged ≥5 years, administered ≥2 months after completing the primary series or after receipt of a monovalent booster dose. . . .
Bivalent COVID-19 vaccine booster doses might improve protection against SARS-CoV-2 Omicron sublineages and, along with completion of a primary series in persons who remain unvaccinated, are important to protect against COVID-19, particularly among those persons who are at increased risk for severe illness and death.
Access the MMWR article in HTML ([link removed]) or PDF ([link removed]) .
Related Links
* MMWR's main page ([link removed]) provides access to MMWR Weekly and its companion publications
* Immunize.org: Checklist of Current Versions of U.S. COVID-19 Vaccination Guidance and Clinic Support Tools ([link removed]) (PDF)
------------------------------------------------------------
Influenza continues its march; step up the vaccine defenses
Roll up your sleeve! Now is the time for you, your patients, and your coworkers to be vaccinated against influenza. Early increases in seasonal influenza activity continue nationwide. High levels of activity are expanding beyond the south. CDC expects influenza activity to continue to increase and spread across the United States in its seasonal epidemic pattern. CDC’s Weekly U.S. Influenza Surveillance Report, FluView ([link removed]) , provides a valuable snapshot of influenza activity state-by-state.
Influenza Surveillance
For week 44, ending November 5, CDC's Weekly U.S. Influenza Surveillance Report, FluView ([link removed]) reports that, nationwide, 5.5% of patient visits reported through the Outpatient Influenza-Like Illness Surveillance Network (ILINet) were due to respiratory illness that included fever plus a cough or sore throat (i.e., influenza-like illness [ILI]). This exceeds the national baseline of 2.5%. Multiple respiratory viruses are co-circulating; the relative contribution of influenza virus infection to ILI varies by location. Sadly, five children died from influenza-associated causes so far during the 2022–23 season.
[link removed]
Influenza Vaccination Dashboard
CDC's Weekly Flu Vaccination Dashboard ([link removed]) data show that 137 million doses of influenza vaccine were distributed in the United States through November 4, 2022. Supplies are sufficient to manage a surge in demand due to early influenza activity.
CDC recommends everyone age 6 months and older get annual influenza vaccination. “Vaccines.gov” offers VaccineFinder ([link removed]) , a service of Boston Children’s Hospital, to help people find influenza and COVID-19 vaccines for any age group. To be listed as a provider by VaccineFinder, see the information at this website ([link removed]) .
If you don’t provide influenza vaccine at your site, please strongly recommend vaccination and refer people to sites that do vaccinate. To enable easy referral to vaccinating sites, the American College of Physicians offers free Adult Vaccination Prescription Pads ([link removed]*drmh0y*_ga*ntqzmzi5mju1lje2nti4mji3nzy.*_ga_pm4f5hbgfq*mty2mju3nde3os4xntkums4xnjyyntc3mdmxlju5ljauma..&_ga=2.227238552.440966330.1662519116-543329255.1652822776&_gac=1.255840506.1661269092.cj0kcqjw9zgybhcearisaeuxitwuuaivyw-epaaozx8nprmbzpmo8erzuefz5wvnwp97z0cragqoeo8aambfealw_wcb) listing ACIP-recommended vaccines.
[link removed]*drmh0y*_ga*ntqzmzi5mju1lje2nti4mji3nzy.*_ga_pm4f5hbgfq*mty2mju3nde3os4xntkums4xnjyyntc3mdmxlju5ljauma..&_ga=2.227238552.440966330.1662519116-543329255.1652822776
Related Links
* CDC: Weekly National Flu Vaccination Dashboard ([link removed]) main page
* CDC: FluView ([link removed]) main page
* CDC: Influenza (Flu) ([link removed]) main page
* Immunize.org: free educational materials and patient handouts related to influenza ([link removed])
* Immunize.org: Vaccines: Influenza ([link removed]) main page
* Immunize.org: Ask the Experts: Influenza ([link removed]) main page
* Families Fighting Flu: Flu Resources for Healthcare Professionals ([link removed]) main page
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Immunize.org remembers our friend and vaccine pioneer Samuel L. Katz, MD (1927–2022)
Samuel L. Katz, M.D., FAAP, who codeveloped the measles vaccine, passed away on October 31 at age 95. Dr. Katz was a world-renowned virologist and pediatrician with degrees from Dartmouth College and Harvard University. He served a medical internship at Beth Israel Hospital and completed pediatrics residency training at Massachusetts General Hospital and Boston Children’s Hospital.
Dr. Katz teamed up with John Enders, Ph.D., who received the Nobel Prize in 1954 for his work with polioviruses. Dr. Katz spent the next 12 years researching viruses, specifically measles, and the two developed an attenuated measles virus vaccine—one of the landmark discoveries in childhood medicine. The measles vaccine was licensed in the United States in 1963. In 1971, it was incorporated into the measles, mumps, and rubella (MMR) vaccine.
[link removed] [link removed]
Dr. Katz then went on to a prominent career in virology and pediatrics and was appointed chair of the Department of Pediatrics at Duke University School of Medicine in 1968, a role he held for 22 years. Dr. Katz represented the Pediatric Infectious Diseases Society on Immunize.org’s advisory board.
Dr. Katz became a renowned advocate for vaccines. He chaired the CDC’s Advisory Committee on Immunization Practices (ACIP) from 1985–1993 and was the recipient of the 2003 Albert B. Sabin Gold Medal, presented to public health leaders who save lives through vaccines.
The World Health Organization estimated that Dr. Katz's measles vaccine saved an estimated 17.1 million lives ([link removed]) between 2000 and 2015.
In addition to his professional accomplishments, he was a kind and caring human being who will be missed by all who knew him.
Related Links
* Duke University School of Medicine: Remembering Samuel L. Katz, MD ([link removed]) (11/2/22)
* Washington Post: Samuel L. Katz, Doctor Who Helped Develop Measles Vaccine, Dies at 95 ([link removed]) (11/3/22)
* AAP: Oral History Project: Samuel Lawrence Katz, MD ([link removed]) (PDF)
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National Community Pharmacists Association releases first episode of "Show Me," an online reality series following pharmacists as they start or improve vaccination programs
The National Community Pharmacists Association ([link removed]) (NCPA) released the first episode of its new online educational reality series titled "Show Me." This series, which is sponsored by Pfizer, is styled after popular TV makeover shows and features real pharmacists who need help getting a certain aspect of their practice on track. This season the subject is vaccinations.
[link removed]
[link removed]
In episode one, coaches Meredith Ayers, CPhT, and Tana N. Kaefer, PharmD, help pharmacy owners Chris and Gwen O’Neill of Circle Pharmacy in Philadelphia find additional streams of revenue by boosting their vaccination program. Find out how they progress in episode one, titled Jumpstart Our Program! ([link removed])
The rest of this season’s five episodes will be released in the coming weeks on NCPA’s various internet platforms including its YouTube channel, NCPAvids ([link removed]) , and its website. Follow @commpharmacy on social media for updates and sneak previews.
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No mixing, no diluting: FDA licenses new Rotarix liquid formulation
On November 4, FDA licensed a new formulation of Rotavirus Vaccine, Live, Oral (Rotarix, GSK). The new formulation is free of porcine circovirus (PCV) and comes as a liquid that does not require mixing or dilution. The single dose oral applicator increases provider convenience.
[link removed]
Both the lyophilized (requires reconstitution) and liquid rotavirus vaccine presentations will remain in use until the lyophilized formulation is used up or expires.
Related Links
* FDA: Rotarix approval letter ([link removed]) (PDF)
* FDA: Package insert for Rotarix ([link removed]) (PDF)
* FDA: Rotarix ([link removed]) main page
* Immunize.org: Product Approval: Rotarix ([link removed]) main page
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Immunize.org's Influenza Vaccination Honor Roll for mandatory healthcare worker vaccination now features 1,294 organizations, including one new facility
Immunize.org's Influenza Vaccination Honor Roll ([link removed]) recognizes facilities that take a stand for patient safety by implementing policies for mandatory healthcare personnel influenza vaccination. There are now 1,294 organizations enrolled. Since October 19, 2022, Immunize.org welcomed one additional healthcare organization.
* OSF Healthcare, Peoria, IL
[link removed]
Eligibility:
* Eligible organizations: Hospitals, long-term care facilities, medical practices, pharmacies, professional organizations, health departments, and other government entities
* Requirements:
+ Your policy must require influenza vaccination for all staff
+ The application ([link removed]) must describe measures to prevent transmission of influenza from unvaccinated personnel to patients (e.g., masking for the entire work shift)
Related Links
* Immunize.org: List of Influenza Vaccination Honorees, all healthcare settings ([link removed]) , by state
* Immunize.org: Long-Term Care/Assisted Living Influenza Vaccination Honorees ([link removed]) by state
* Immunize.org: Influenza Vaccination Honor Roll program ([link removed]) , including:
+ Position statements ([link removed]) from professional societies and leading healthcare organizations in support of mandatory influenza vaccination
+ Application form for Influenza Vaccination Honor Roll ([link removed])
* Immunize.org: Honor Roll for Patient Safety ([link removed]) web page
------------------------------------------------------------
Spotlight: Immunize.org's "Handouts" main page provides free access to hundreds of vaccination-related handouts and fact sheets
Immunize.org's Handouts for Patients and Staff ([link removed]) web page leads users to hundreds of free vaccination-related patient handouts and fact sheets for healthcare professionals. All items are ready to print, copy, and distribute widely.
Visit the Handouts for Patients and Staff ([link removed]) web page to view more than 230 handouts sorted by:
* Topic ([link removed])
* Vaccine ([link removed])
* Language ([link removed])
[link removed]
From the main page, you can search by any of the 22 topics. Some of the most popular are:
* Administering Vaccines ([link removed])
* Parent Handouts ([link removed])
* Screening Checklists ([link removed])
* Standing Orders ([link removed])
* Temperature Logs ([link removed])
* Top Handouts ([link removed])
The right-hand side of the web page includes links to some of Immunize.org's most popular handouts, including:
* Summary of Recommendations for Children and Teens ([link removed])
* Summary of Recommendations for Adults ([link removed])
* Vaccinations for Adults—You’re Never Too Old to Get Immunized ([link removed])
* When Do Children and Teens Need Vaccinations? ([link removed])
* How to Administer Intramuscular and Subcutaneous Vaccine Injections: Administration by the Intramuscular (IM) Route ([link removed])
You can also view an alphabetical listing of Immunize.org’s more than 230 ready-to-print staff educational materials and patient handouts ([link removed]) .
Visit Immunize.org's Handouts for Patients and Staff ([link removed]) web page today!
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Vaccines in the news
These recent articles convey the potential risks of vaccine-preventable diseases and the importance of vaccination.
* Wall Street Journal: How Does Flu Spread Compared with COVID? What to Know as Flu Cases Surge ([link removed]) (11/8/22)
* The Guardian: U.S. Hospital Flu Cases Highest in a Decade amid Winter Vaccination Warning ([link removed]) (11/5/22)
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Immunize.org Pages and Handouts
------------------------------------------------------------
Immunize.org updates two standing orders templates for administering hepatitis A vaccine—one for children and teens and one for adults
Immunize.org revised two handouts, Standing Orders for Administering Hepatitis A Vaccine to Children and Teens ([link removed]) and Standing Orders for Administering Hepatitis A Vaccine to Adults ([link removed]) , with QR codes, a new footer, and minor revisions. "Standing Orders for Administering Hepatitis A Vaccine to Children and Teens" was also revised to describe the anterolateral thigh as an alternative injection site.
[link removed] [link removed]
Related Links
* Immunize.org: Standing Orders Templates for Administering Vaccines ([link removed]) main page
* Immunize.org: Vaccines: Hepatitis A ([link removed]) main page
* Immunize.org: Handouts for Patients and Staff ([link removed]) main page, where you can sort materials by topic, vaccine, or language
* Immunize.org: Educational Materials for Patients and Staff ([link removed]) —an alphabetical listing of more than 230 ready-to-print staff educational materials and patient handouts
------------------------------------------------------------
Featured Resources
------------------------------------------------------------
Voices for Vaccines releases podcast on mRNA vaccines and what the future may hold
Voices for Vaccines (VFV) posted a new entry in its Vax Talk podcast series: The Future of mRNA Vaccines ([link removed]) featuring Melissa Moore, PhD, Chief Scientific Officer for Moderna. A description from the VFV web page appears below.
In many ways, mRNA vaccines are a game-changer, but not an unexpected one. For this episode, we talked to one of the scientists who has been pursuing mRNA vaccines for years: Melissa Moore, Ph.D. We discuss how mRNA vaccines have changed so much for us and what the future might hold.
[link removed]
Voices for Vaccines is a national organization of parents and others dedicated to raising the level of the voices of immunization supporters. VFV invites everyone who values vaccines to become a member, use VFV tools in their own community, and get involved with VFV ([link removed]).
Related Links
* Voices for Vaccines: Resources ([link removed]) main page
* Voices for Vaccines podcast page ([link removed])
------------------------------------------------------------
Organizing a new vaccination program? Use Immunize.org’s Vaccinating Adults: A Step-by-Step Guide—free to download by chapter or in its entirety.
Download Immunize.org’s free 142-page book on adult vaccination to help build your program and train your team: Vaccinating Adults: A Step-by-Step Guide (Guide) ([link removed]).
[link removed]
This thorough "how to" guide on adult vaccination provides easy-to-use, practical information covering all essential activities. It helps vaccine providers enhance their existing adult vaccination services or introduce them into any clinical setting.
The Guide is available to download/print either by chapter or in its entirety free at www.immunize.org/guide ([link removed]) . The National Vaccine Program Office and CDC both supported the development of the Guide and provided early technical review.
The Guide is a valuable resource to assist providers in increasing adult vaccination rates. Be sure to get a copy today!
Please note: this guide was produced in 2017, before the COVID-19 era, and reflects the recommendations of that time.
Related Links
* Vaccinating Adults: A Step-by-Step Guide ([link removed]) main page, permitting download of entire Guide (142 pages, PDF) ([link removed])
* View the table of contents and individual chapters (PDF):
+ Table of Contents ([link removed])
+ Step 1: Getting Started ([link removed])
+ Step 2: Setting Up for Vaccination Services ([link removed])
+ Step 3: Vaccine Storage and Handling ([link removed])
+ Step 4: Deciding Whom to Vaccinate ([link removed])
+ Step 5: Administering Vaccines ([link removed])
+ Step 6: Documentation and Related Issues ([link removed])
+ Step 7A: Financial Considerations ([link removed])
+ Step 7B: How to Bill for Adult Immunizations ([link removed])
* Immunize.org’s educational materials (handouts) on adult immunization ([link removed])
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Notable Publications
------------------------------------------------------------
“Preferential Recommendations for Vaccines: Time for a Structured, Transparent Process” commentary published online in Vaccine
Preferential Recommendations for Vaccines: Time for a Structured Transparent Process ([link removed]) , a commentary by Immunize.org's President and Chief Executive Officer, Kelly L. Moore, MD, MPH, and the Chief Policy and Partnerships Officer, Litjen (L.J) Tan, MS, PhD, is now posted ahead of print by Vaccine. In the commentary, the authors note:
The approach used to determine preferential and non-preferential ACIP recommendations can positively or negatively affect vaccine innovation. A well-reasoned preference rewards better vaccine performance and provides clear guidance to clinicians and patients. Absence of a preference in the presence of clinically significant differences in product performance may confuse clinicians and impede the adoption of better, more expensive—but not preferred—options in health systems that select products on the basis of cost alone. . . .
We propose that now is the time to establish an ACIP-led working group, including experts from the National Vaccine Advisory Committee (NVAC), to define a framework that will elucidate the process and criteria necessary for preferential recommendations. Preferential use criteria must include vaccine efficacy/effectiveness data, clinical impact, cost-effectiveness, implementation considerations, health equity and other values, as well as vaccine supply, packaging, and market concerns that will likely vary by disease and by vaccine.
Full citation details for the article will be added when the final version becomes available.
------------------------------------------------------------
“COVID-19–Associated Hospitalizations among U.S. Infants Aged <6 Months—COVID-NET, 13 States, June 2021–August 2022” published in MMWR
CDC published COVID-19–Associated Hospitalizations among U.S. Infants Aged <6 Months—COVID-NET, 13 States, June 2021–August 2022 ([link removed]) on November 11 in MMWR. A portion of the summary appears below.
Infants aged <6 months, who are ineligible for vaccination, have high COVID-19–associated hospitalization rates compared with other pediatric age groups. . . .
Although population-based COVID-19–associated hospitalization rates among infants aged <6 months increased in the Omicron variant–predominant periods compared with the Delta variant–predominant period, indicators of the most severe disease among hospitalized infants aged <6 months did not. . . .
Pregnant women should stay up to date with COVID-19 vaccination to help protect themselves and infants too young to be vaccinated. Nonpharmaceutical measures should be used to help protect infants ineligible for vaccination.
[link removed]
Access the MMWR article in HTML ([link removed]) or PDF ([link removed]) .
Related Link
* MMWR's main page ([link removed]) provides access to MMWR Weekly and its companion publications
------------------------------------------------------------
“Epidemiologic Features of the Monkeypox Outbreak and the Public Health Response—United States, May 17–October 6, 2022” published in MMWR
CDC published Epidemiologic Features of the Monkeypox Outbreak and the Public Health Response—United States, May 17–October 6, 2022 ([link removed]) on November 11 in MMWR. A portion of the summary appears below.
An earlier analysis of 2,891 U.S. monkeypox cases found that up to 99% occurred in men, 94% of whom reported male-to-male sexual contact. . . .
CDC’s emergency response focused on surveillance, laboratory testing, medical countermeasures, and education. A total of 26,384 U.S. monkeypox cases were reported during May 17–October 6, 2022. Among 59% of persons with data on gender and recent sexual or close intimate contact, 70% reported recent male-to-male sexual contact. Black and Hispanic persons continue to be disproportionately affected. . . .
Public health monkeypox prevention efforts, including vaccination, should continue to prioritize gay, bisexual, and other men who have sex with men, Black and Hispanic persons, and persons who are immunocompromised.
[link removed]
Access the MMWR article in HTML ([link removed]) or PDF ([link removed]) .
Related Link
* MMWR's main page ([link removed]) provides access to MMWR Weekly and its companion publications
------------------------------------------------------------
For more upcoming events, visit our Calendar of Events ([link removed]) .
Editorial Information
Editor-in-Chief
Kelly L. Moore, MD, MPH
Managing Editor
John D. Grabenstein, RPh, PhD
Associate Editor
Sharon G. Humiston, MD, MPH
Writer/Publication Coordinator
Taryn Chapman, MS
Courtnay Londo, MA
Style and Copy Editor
Marian Deegan, JD
Web Edition Managers
Arkady Shakhnovich
Jermaine Royes
Contributing Writer
Laurel H. Wood, MPA
Technical Reviewer
Kayla Ohlde
About IZ Express
Immunize.org welcomes redistribution of this issue of IZ Express or selected articles.
When you do so, please add a note that Immunize.org is the source of the material and provide a link to this issue ([link removed]) .
IZ Express is supported in part by Grant No. 1NH23IP922654 from the National Center for Immunization and Respiratory Diseases, CDC. Its contents are solely the responsibility of Immunize.org and do not necessarily represent the official views of CDC.
IZ Express Disclaimer ([link removed])
ISSN: 2771-8085
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Issue 1,663: November 16, 2022
Top Stories
* “Interim Recommendations from the Advisory Committee on Immunization Practices for the Use of Bivalent Booster Doses of COVID-19 Vaccines—United States, 2022” published in MMWR describing ACIP votes on September 1 and October 12, 2022
* Influenza continues its march; step up the vaccine defenses
* Immunize.org remembers our friend and vaccine pioneer Samuel L. Katz, MD (1927–2022)
* National Community Pharmacists Association releases first episode of "Show Me," an online reality series following pharmacists as they start or improve vaccination programs
* No mixing, no diluting: FDA licenses new Rotarix liquid formulation
* Immunize.org's Influenza Vaccination Honor Roll for mandatory healthcare worker vaccination now features 1,294 organizations, including one new facility
* Spotlight: Immunize.org's "Handouts" main page provides free access to hundreds of vaccination-related handouts and fact sheets
* Vaccines in the news
Immunize.org Pages and Handouts
* Immunize.org updates two standing orders templates for administering hepatitis A vaccine—one for children and teens and one for adults
Featured Resources
* Voices for Vaccines releases podcast on mRNA vaccines and what the future may hold
* Organizing a new vaccination program? Use Immunize.org’s Vaccinating Adults: A Step-by-Step Guide—free to download by chapter or in its entirety.
Notable Publications
* “Preferential Recommendations for Vaccines: Time for a Structured, Transparent Process” commentary published online in Vaccine
* “COVID-19–Associated Hospitalizations among U.S. Infants Aged <6 Months—COVID-NET, 13 States, June 2021–August 2022” published in MMWR
* “Epidemiologic Features of the Monkeypox Outbreak and the Public Health Response—United States, May 17–October 6, 2022” published in MMWR
------------------------------------------------------------
Top Stories
------------------------------------------------------------
“Interim Recommendations from the Advisory Committee on Immunization Practices for the Use of Bivalent Booster Doses of COVID-19 Vaccines—United States, 2022” published in MMWR describing ACIP votes on September 1 and October 12, 2022
CDC published Interim Recommendations from the Advisory Committee on Immunization Practices for the Use of Bivalent Booster Doses of COVID-19 Vaccines—United States, 2022 ([link removed]) ([link removed]) on November 11 in MMWR. The recommendations described were approved by ACIP on September 1 and October 12. A portion of the summary appears below.
In the United States, COVID-19 monovalent booster vaccination was previously recommended, but related protection decreased after the emergence of Omicron subvariants. . . .
In fall 2022, CDC recommended a bivalent mRNA COVID-19 vaccine booster dose for persons aged ≥5 years, administered ≥2 months after completing the primary series or after receipt of a monovalent booster dose. . . .
Bivalent COVID-19 vaccine booster doses might improve protection against SARS-CoV-2 Omicron sublineages and, along with completion of a primary series in persons who remain unvaccinated, are important to protect against COVID-19, particularly among those persons who are at increased risk for severe illness and death.
Access the MMWR article in HTML ([link removed]) or PDF ([link removed]) .
Related Links
* MMWR's main page ([link removed]) provides access to MMWR Weekly and its companion publications
* Immunize.org: Checklist of Current Versions of U.S. COVID-19 Vaccination Guidance and Clinic Support Tools ([link removed]) (PDF)
------------------------------------------------------------
Influenza continues its march; step up the vaccine defenses
Roll up your sleeve! Now is the time for you, your patients, and your coworkers to be vaccinated against influenza. Early increases in seasonal influenza activity continue nationwide. High levels of activity are expanding beyond the south. CDC expects influenza activity to continue to increase and spread across the United States in its seasonal epidemic pattern. CDC’s Weekly U.S. Influenza Surveillance Report, FluView ([link removed]) , provides a valuable snapshot of influenza activity state-by-state.
Influenza Surveillance
For week 44, ending November 5, CDC's Weekly U.S. Influenza Surveillance Report, FluView ([link removed]) reports that, nationwide, 5.5% of patient visits reported through the Outpatient Influenza-Like Illness Surveillance Network (ILINet) were due to respiratory illness that included fever plus a cough or sore throat (i.e., influenza-like illness [ILI]). This exceeds the national baseline of 2.5%. Multiple respiratory viruses are co-circulating; the relative contribution of influenza virus infection to ILI varies by location. Sadly, five children died from influenza-associated causes so far during the 2022–23 season.
[link removed]
Influenza Vaccination Dashboard
CDC's Weekly Flu Vaccination Dashboard ([link removed]) data show that 137 million doses of influenza vaccine were distributed in the United States through November 4, 2022. Supplies are sufficient to manage a surge in demand due to early influenza activity.
CDC recommends everyone age 6 months and older get annual influenza vaccination. “Vaccines.gov” offers VaccineFinder ([link removed]) , a service of Boston Children’s Hospital, to help people find influenza and COVID-19 vaccines for any age group. To be listed as a provider by VaccineFinder, see the information at this website ([link removed]) .
If you don’t provide influenza vaccine at your site, please strongly recommend vaccination and refer people to sites that do vaccinate. To enable easy referral to vaccinating sites, the American College of Physicians offers free Adult Vaccination Prescription Pads ([link removed]*drmh0y*_ga*ntqzmzi5mju1lje2nti4mji3nzy.*_ga_pm4f5hbgfq*mty2mju3nde3os4xntkums4xnjyyntc3mdmxlju5ljauma..&_ga=2.227238552.440966330.1662519116-543329255.1652822776&_gac=1.255840506.1661269092.cj0kcqjw9zgybhcearisaeuxitwuuaivyw-epaaozx8nprmbzpmo8erzuefz5wvnwp97z0cragqoeo8aambfealw_wcb) listing ACIP-recommended vaccines.
[link removed]*drmh0y*_ga*ntqzmzi5mju1lje2nti4mji3nzy.*_ga_pm4f5hbgfq*mty2mju3nde3os4xntkums4xnjyyntc3mdmxlju5ljauma..&_ga=2.227238552.440966330.1662519116-543329255.1652822776
Related Links
* CDC: Weekly National Flu Vaccination Dashboard ([link removed]) main page
* CDC: FluView ([link removed]) main page
* CDC: Influenza (Flu) ([link removed]) main page
* Immunize.org: free educational materials and patient handouts related to influenza ([link removed])
* Immunize.org: Vaccines: Influenza ([link removed]) main page
* Immunize.org: Ask the Experts: Influenza ([link removed]) main page
* Families Fighting Flu: Flu Resources for Healthcare Professionals ([link removed]) main page
------------------------------------------------------------
Immunize.org remembers our friend and vaccine pioneer Samuel L. Katz, MD (1927–2022)
Samuel L. Katz, M.D., FAAP, who codeveloped the measles vaccine, passed away on October 31 at age 95. Dr. Katz was a world-renowned virologist and pediatrician with degrees from Dartmouth College and Harvard University. He served a medical internship at Beth Israel Hospital and completed pediatrics residency training at Massachusetts General Hospital and Boston Children’s Hospital.
Dr. Katz teamed up with John Enders, Ph.D., who received the Nobel Prize in 1954 for his work with polioviruses. Dr. Katz spent the next 12 years researching viruses, specifically measles, and the two developed an attenuated measles virus vaccine—one of the landmark discoveries in childhood medicine. The measles vaccine was licensed in the United States in 1963. In 1971, it was incorporated into the measles, mumps, and rubella (MMR) vaccine.
[link removed] [link removed]
Dr. Katz then went on to a prominent career in virology and pediatrics and was appointed chair of the Department of Pediatrics at Duke University School of Medicine in 1968, a role he held for 22 years. Dr. Katz represented the Pediatric Infectious Diseases Society on Immunize.org’s advisory board.
Dr. Katz became a renowned advocate for vaccines. He chaired the CDC’s Advisory Committee on Immunization Practices (ACIP) from 1985–1993 and was the recipient of the 2003 Albert B. Sabin Gold Medal, presented to public health leaders who save lives through vaccines.
The World Health Organization estimated that Dr. Katz's measles vaccine saved an estimated 17.1 million lives ([link removed]) between 2000 and 2015.
In addition to his professional accomplishments, he was a kind and caring human being who will be missed by all who knew him.
Related Links
* Duke University School of Medicine: Remembering Samuel L. Katz, MD ([link removed]) (11/2/22)
* Washington Post: Samuel L. Katz, Doctor Who Helped Develop Measles Vaccine, Dies at 95 ([link removed]) (11/3/22)
* AAP: Oral History Project: Samuel Lawrence Katz, MD ([link removed]) (PDF)
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National Community Pharmacists Association releases first episode of "Show Me," an online reality series following pharmacists as they start or improve vaccination programs
The National Community Pharmacists Association ([link removed]) (NCPA) released the first episode of its new online educational reality series titled "Show Me." This series, which is sponsored by Pfizer, is styled after popular TV makeover shows and features real pharmacists who need help getting a certain aspect of their practice on track. This season the subject is vaccinations.
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In episode one, coaches Meredith Ayers, CPhT, and Tana N. Kaefer, PharmD, help pharmacy owners Chris and Gwen O’Neill of Circle Pharmacy in Philadelphia find additional streams of revenue by boosting their vaccination program. Find out how they progress in episode one, titled Jumpstart Our Program! ([link removed])
The rest of this season’s five episodes will be released in the coming weeks on NCPA’s various internet platforms including its YouTube channel, NCPAvids ([link removed]) , and its website. Follow @commpharmacy on social media for updates and sneak previews.
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No mixing, no diluting: FDA licenses new Rotarix liquid formulation
On November 4, FDA licensed a new formulation of Rotavirus Vaccine, Live, Oral (Rotarix, GSK). The new formulation is free of porcine circovirus (PCV) and comes as a liquid that does not require mixing or dilution. The single dose oral applicator increases provider convenience.
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Both the lyophilized (requires reconstitution) and liquid rotavirus vaccine presentations will remain in use until the lyophilized formulation is used up or expires.
Related Links
* FDA: Rotarix approval letter ([link removed]) (PDF)
* FDA: Package insert for Rotarix ([link removed]) (PDF)
* FDA: Rotarix ([link removed]) main page
* Immunize.org: Product Approval: Rotarix ([link removed]) main page
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Immunize.org's Influenza Vaccination Honor Roll for mandatory healthcare worker vaccination now features 1,294 organizations, including one new facility
Immunize.org's Influenza Vaccination Honor Roll ([link removed]) recognizes facilities that take a stand for patient safety by implementing policies for mandatory healthcare personnel influenza vaccination. There are now 1,294 organizations enrolled. Since October 19, 2022, Immunize.org welcomed one additional healthcare organization.
* OSF Healthcare, Peoria, IL
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Eligibility:
* Eligible organizations: Hospitals, long-term care facilities, medical practices, pharmacies, professional organizations, health departments, and other government entities
* Requirements:
+ Your policy must require influenza vaccination for all staff
+ The application ([link removed]) must describe measures to prevent transmission of influenza from unvaccinated personnel to patients (e.g., masking for the entire work shift)
Related Links
* Immunize.org: List of Influenza Vaccination Honorees, all healthcare settings ([link removed]) , by state
* Immunize.org: Long-Term Care/Assisted Living Influenza Vaccination Honorees ([link removed]) by state
* Immunize.org: Influenza Vaccination Honor Roll program ([link removed]) , including:
+ Position statements ([link removed]) from professional societies and leading healthcare organizations in support of mandatory influenza vaccination
+ Application form for Influenza Vaccination Honor Roll ([link removed])
* Immunize.org: Honor Roll for Patient Safety ([link removed]) web page
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Spotlight: Immunize.org's "Handouts" main page provides free access to hundreds of vaccination-related handouts and fact sheets
Immunize.org's Handouts for Patients and Staff ([link removed]) web page leads users to hundreds of free vaccination-related patient handouts and fact sheets for healthcare professionals. All items are ready to print, copy, and distribute widely.
Visit the Handouts for Patients and Staff ([link removed]) web page to view more than 230 handouts sorted by:
* Topic ([link removed])
* Vaccine ([link removed])
* Language ([link removed])
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From the main page, you can search by any of the 22 topics. Some of the most popular are:
* Administering Vaccines ([link removed])
* Parent Handouts ([link removed])
* Screening Checklists ([link removed])
* Standing Orders ([link removed])
* Temperature Logs ([link removed])
* Top Handouts ([link removed])
The right-hand side of the web page includes links to some of Immunize.org's most popular handouts, including:
* Summary of Recommendations for Children and Teens ([link removed])
* Summary of Recommendations for Adults ([link removed])
* Vaccinations for Adults—You’re Never Too Old to Get Immunized ([link removed])
* When Do Children and Teens Need Vaccinations? ([link removed])
* How to Administer Intramuscular and Subcutaneous Vaccine Injections: Administration by the Intramuscular (IM) Route ([link removed])
You can also view an alphabetical listing of Immunize.org’s more than 230 ready-to-print staff educational materials and patient handouts ([link removed]) .
Visit Immunize.org's Handouts for Patients and Staff ([link removed]) web page today!
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Vaccines in the news
These recent articles convey the potential risks of vaccine-preventable diseases and the importance of vaccination.
* Wall Street Journal: How Does Flu Spread Compared with COVID? What to Know as Flu Cases Surge ([link removed]) (11/8/22)
* The Guardian: U.S. Hospital Flu Cases Highest in a Decade amid Winter Vaccination Warning ([link removed]) (11/5/22)
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Immunize.org Pages and Handouts
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Immunize.org updates two standing orders templates for administering hepatitis A vaccine—one for children and teens and one for adults
Immunize.org revised two handouts, Standing Orders for Administering Hepatitis A Vaccine to Children and Teens ([link removed]) and Standing Orders for Administering Hepatitis A Vaccine to Adults ([link removed]) , with QR codes, a new footer, and minor revisions. "Standing Orders for Administering Hepatitis A Vaccine to Children and Teens" was also revised to describe the anterolateral thigh as an alternative injection site.
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Related Links
* Immunize.org: Standing Orders Templates for Administering Vaccines ([link removed]) main page
* Immunize.org: Vaccines: Hepatitis A ([link removed]) main page
* Immunize.org: Handouts for Patients and Staff ([link removed]) main page, where you can sort materials by topic, vaccine, or language
* Immunize.org: Educational Materials for Patients and Staff ([link removed]) —an alphabetical listing of more than 230 ready-to-print staff educational materials and patient handouts
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Featured Resources
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Voices for Vaccines releases podcast on mRNA vaccines and what the future may hold
Voices for Vaccines (VFV) posted a new entry in its Vax Talk podcast series: The Future of mRNA Vaccines ([link removed]) featuring Melissa Moore, PhD, Chief Scientific Officer for Moderna. A description from the VFV web page appears below.
In many ways, mRNA vaccines are a game-changer, but not an unexpected one. For this episode, we talked to one of the scientists who has been pursuing mRNA vaccines for years: Melissa Moore, Ph.D. We discuss how mRNA vaccines have changed so much for us and what the future might hold.
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Voices for Vaccines is a national organization of parents and others dedicated to raising the level of the voices of immunization supporters. VFV invites everyone who values vaccines to become a member, use VFV tools in their own community, and get involved with VFV ([link removed]).
Related Links
* Voices for Vaccines: Resources ([link removed]) main page
* Voices for Vaccines podcast page ([link removed])
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Organizing a new vaccination program? Use Immunize.org’s Vaccinating Adults: A Step-by-Step Guide—free to download by chapter or in its entirety.
Download Immunize.org’s free 142-page book on adult vaccination to help build your program and train your team: Vaccinating Adults: A Step-by-Step Guide (Guide) ([link removed]).
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This thorough "how to" guide on adult vaccination provides easy-to-use, practical information covering all essential activities. It helps vaccine providers enhance their existing adult vaccination services or introduce them into any clinical setting.
The Guide is available to download/print either by chapter or in its entirety free at www.immunize.org/guide ([link removed]) . The National Vaccine Program Office and CDC both supported the development of the Guide and provided early technical review.
The Guide is a valuable resource to assist providers in increasing adult vaccination rates. Be sure to get a copy today!
Please note: this guide was produced in 2017, before the COVID-19 era, and reflects the recommendations of that time.
Related Links
* Vaccinating Adults: A Step-by-Step Guide ([link removed]) main page, permitting download of entire Guide (142 pages, PDF) ([link removed])
* View the table of contents and individual chapters (PDF):
+ Table of Contents ([link removed])
+ Step 1: Getting Started ([link removed])
+ Step 2: Setting Up for Vaccination Services ([link removed])
+ Step 3: Vaccine Storage and Handling ([link removed])
+ Step 4: Deciding Whom to Vaccinate ([link removed])
+ Step 5: Administering Vaccines ([link removed])
+ Step 6: Documentation and Related Issues ([link removed])
+ Step 7A: Financial Considerations ([link removed])
+ Step 7B: How to Bill for Adult Immunizations ([link removed])
* Immunize.org’s educational materials (handouts) on adult immunization ([link removed])
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Notable Publications
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“Preferential Recommendations for Vaccines: Time for a Structured, Transparent Process” commentary published online in Vaccine
Preferential Recommendations for Vaccines: Time for a Structured Transparent Process ([link removed]) , a commentary by Immunize.org's President and Chief Executive Officer, Kelly L. Moore, MD, MPH, and the Chief Policy and Partnerships Officer, Litjen (L.J) Tan, MS, PhD, is now posted ahead of print by Vaccine. In the commentary, the authors note:
The approach used to determine preferential and non-preferential ACIP recommendations can positively or negatively affect vaccine innovation. A well-reasoned preference rewards better vaccine performance and provides clear guidance to clinicians and patients. Absence of a preference in the presence of clinically significant differences in product performance may confuse clinicians and impede the adoption of better, more expensive—but not preferred—options in health systems that select products on the basis of cost alone. . . .
We propose that now is the time to establish an ACIP-led working group, including experts from the National Vaccine Advisory Committee (NVAC), to define a framework that will elucidate the process and criteria necessary for preferential recommendations. Preferential use criteria must include vaccine efficacy/effectiveness data, clinical impact, cost-effectiveness, implementation considerations, health equity and other values, as well as vaccine supply, packaging, and market concerns that will likely vary by disease and by vaccine.
Full citation details for the article will be added when the final version becomes available.
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“COVID-19–Associated Hospitalizations among U.S. Infants Aged <6 Months—COVID-NET, 13 States, June 2021–August 2022” published in MMWR
CDC published COVID-19–Associated Hospitalizations among U.S. Infants Aged <6 Months—COVID-NET, 13 States, June 2021–August 2022 ([link removed]) on November 11 in MMWR. A portion of the summary appears below.
Infants aged <6 months, who are ineligible for vaccination, have high COVID-19–associated hospitalization rates compared with other pediatric age groups. . . .
Although population-based COVID-19–associated hospitalization rates among infants aged <6 months increased in the Omicron variant–predominant periods compared with the Delta variant–predominant period, indicators of the most severe disease among hospitalized infants aged <6 months did not. . . .
Pregnant women should stay up to date with COVID-19 vaccination to help protect themselves and infants too young to be vaccinated. Nonpharmaceutical measures should be used to help protect infants ineligible for vaccination.
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Access the MMWR article in HTML ([link removed]) or PDF ([link removed]) .
Related Link
* MMWR's main page ([link removed]) provides access to MMWR Weekly and its companion publications
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“Epidemiologic Features of the Monkeypox Outbreak and the Public Health Response—United States, May 17–October 6, 2022” published in MMWR
CDC published Epidemiologic Features of the Monkeypox Outbreak and the Public Health Response—United States, May 17–October 6, 2022 ([link removed]) on November 11 in MMWR. A portion of the summary appears below.
An earlier analysis of 2,891 U.S. monkeypox cases found that up to 99% occurred in men, 94% of whom reported male-to-male sexual contact. . . .
CDC’s emergency response focused on surveillance, laboratory testing, medical countermeasures, and education. A total of 26,384 U.S. monkeypox cases were reported during May 17–October 6, 2022. Among 59% of persons with data on gender and recent sexual or close intimate contact, 70% reported recent male-to-male sexual contact. Black and Hispanic persons continue to be disproportionately affected. . . .
Public health monkeypox prevention efforts, including vaccination, should continue to prioritize gay, bisexual, and other men who have sex with men, Black and Hispanic persons, and persons who are immunocompromised.
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Access the MMWR article in HTML ([link removed]) or PDF ([link removed]) .
Related Link
* MMWR's main page ([link removed]) provides access to MMWR Weekly and its companion publications
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For more upcoming events, visit our Calendar of Events ([link removed]) .
Editorial Information
Editor-in-Chief
Kelly L. Moore, MD, MPH
Managing Editor
John D. Grabenstein, RPh, PhD
Associate Editor
Sharon G. Humiston, MD, MPH
Writer/Publication Coordinator
Taryn Chapman, MS
Courtnay Londo, MA
Style and Copy Editor
Marian Deegan, JD
Web Edition Managers
Arkady Shakhnovich
Jermaine Royes
Contributing Writer
Laurel H. Wood, MPA
Technical Reviewer
Kayla Ohlde
About IZ Express
Immunize.org welcomes redistribution of this issue of IZ Express or selected articles.
When you do so, please add a note that Immunize.org is the source of the material and provide a link to this issue ([link removed]) .
IZ Express is supported in part by Grant No. 1NH23IP922654 from the National Center for Immunization and Respiratory Diseases, CDC. Its contents are solely the responsibility of Immunize.org and do not necessarily represent the official views of CDC.
IZ Express Disclaimer ([link removed])
ISSN: 2771-8085
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