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IZ Express #1,656: CDC’s web tool with data on adult vaccination rates, and more
| From | Immunize.org <[email protected]> |
| Subject | IZ Express #1,656: CDC’s web tool with data on adult vaccination rates, and more |
| Date | October 5, 2022 10:01 AM |
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Issue 1,656: October 5, 2022
Top Stories
* View your state’s stats. CDC’s interactive web tool updated with 2021 Behavioral Risk Factor Surveillance System (BRFSS) data on adult vaccination rates.
* “Cholera Vaccine: Recommendations of the Advisory Committee on Immunization Practices, 2022” published in MMWR Recommendations and Reports
* "Incidence of Monkeypox among Unvaccinated Persons Compared with Persons Receiving ≥1 Jynneos Vaccine Dose—32 U.S. Jurisdictions, July 31–September 3, 2022" published in MMWR Early Release
* Keep up with influenza this season: use CDC’s FluView surveillance reports and Influenza Vaccination Dashboard, updated weekly
* World Meningitis Day celebrated October 5. Are you advocating for adolescents to get MenB and second-dose MenACWY vaccine?
* Invite your colleagues to subscribe to IZ Express so they don’t miss the latest immunization news!
* Spotlight: “Ask the Experts” answers more than 1,200 questions on vaccines and vaccinations
* Journalists interview Immunize.org experts
* Vaccines in the news
Immunize.org Pages and Handouts
* Immunize.org updates its patient handout, "You're 16...We Recommend These Vaccines for You!"
* Recap: These updated Immunize.org educational materials and web pages for clinicians were released during August and September
* Immunize.org updates “Pre-exposure Management for Healthcare Personnel with a Documented Hepatitis B Vaccine Series Who Have Not Had Post-vaccination Serologic Testing”
Vaccine Information Statements
* Recap: These new VISs and VIS translations were released during August and September
Featured Resources
* Explore the www.Give2MenACWY.org website to increase coverage for the MenACWY booster and other adolescent vaccinations
Notable Publications
* “Association between Aluminum Exposure from Vaccines before Age 24 Months and Persistent Asthma at Age 24 to 59 Months” published in Academic Pediatrics
* NIH-funded study links COVID-19 vaccination and temporary increase in menstrual cycle length
* "Estimation of COVID-19 mRNA Vaccine Effectiveness against Medically Attended COVID-19 in Pregnancy during Periods of Delta and Omicron Variant Predominance in the United States" published in JAMA Network
* “Widespread Hepatitis A Outbreaks Associated with Person-to-Person Transmission—United States, 2016–2020” published in MMWR
* “Effectiveness of a Second COVID-19 Vaccine Booster Dose against Infection, Hospitalization, or Death among Nursing Home Residents—19 States, March 29–July 25, 2022” published in MMWR
Upcoming Events
* Virtual: National Foundation for Infectious Diseases hosts "Clinical Vaccinology Course" on November 16–18; CME/CNE available
* On-demand: CDC’s “The Pink Book” chapter webinars on vaccine-preventable diseases and best practices roll out weekly. HPV webinar now available, with CE.
Editorial Information
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Top Stories
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View your state’s stats. CDC’s interactive web tool updated with 2021 Behavioral Risk Factor Surveillance System (BRFSS) data on adult vaccination rates.
Behavioral Risk Factor Surveillance System (BRFSS) ([link removed]) data for 2021 are now available through CDC’s easy-to-use web-based tool. Topics include self-reported use of preventive services, including adult vaccination. Updated annually, the prevalence and trends tool ([link removed]) offers fast access to a large portion of the 2021 data set and can be a helpful resource to reporters, vaccine advocates, students, public-health officials, and decision-makers. The tool is updated every year.
BRFSS prevalence and trends data are available for all states and territories. An example map showing adults aged 65+ vaccinated against influenza within the past year appears below.
Related Links
* CDC Media Release: CDC Releases Data on Chronic Diseases and Related Risk Factors ([link removed]) (9/27/22)
* CDC: BRFSS Prevalence & Trends Data ([link removed])
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“Cholera Vaccine: Recommendations of the Advisory Committee on Immunization Practices, 2022” published in MMWR Recommendations and Reports
CDC published Cholera Vaccine: Recommendations of the Advisory Committee on Immunization Practices, 2022 ([link removed]) in the September 30 issue of MMWR Recommendations and Reports. A portion of the summary appears below.
Cholera is rare in the United States, but cases occur among travelers to countries where cholera is endemic or epidemic and associated with unsafe water and inadequate sanitation. Travelers might be at increased risk for poor outcomes from cholera if they cannot readily access medical services or if they have a medical condition that would be worsened by dehydration, such as cardiovascular or kidney disease. This report describes previously published ACIP recommendations about use of CVD 103-HgR for adults aged 18–64 years and introduces a new recommendation for use in children and adolescents aged 2–17 years. ACIP recommends CVD 103-HgR, the only cholera vaccine licensed for use in the United States, for prevention of cholera among travelers aged 2–64 years to an area with active cholera transmission. Health care providers can use these guidelines to develop the pretravel consultation for persons traveling to areas with active cholera transmission.
Access the MMWR article in HTML ([link removed]) or PDF ([link removed]).
Related Links
* Emergent Biosolutions: Vaxchora Package Insert ([link removed])
* FDA: Product Approval – Cholera ([link removed])
* Immunize.org: Package Inserts and FDA Product Approvals ([link removed]) web page
* Immunize.org: ACIP Recommendations ([link removed]) web page
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"Incidence of Monkeypox among Unvaccinated Persons Compared with Persons Receiving ≥1 Jynneos Vaccine Dose—32 U.S. Jurisdictions, July 31–September 3, 2022" published in MMWR Early Release
CDC published Incidence of Monkeypox among Unvaccinated Persons Compared with Persons Receiving ≥1 Jynneos Vaccine Dose—32 U.S. Jurisdictions, July 31–September 3, 2022 ([link removed]) in the September 30 issue of MMWR Early Release. The summary appears below.
Across 32 U.S. jurisdictions, among males aged 18–49 years eligible for JYNNEOS vaccination, monkeypox incidence was 14 times as high among unvaccinated males compared with those who had received a first vaccine dose ≥14 days earlier. . . .
These early findings suggest that a single JYNNEOS dose provides some protection against monkeypox infection. The degree and durability of such protection is unknown, and it is recommended that persons who are eligible for monkeypox vaccination receive the complete 2-dose series.
Access the MMWR article in HTML ([link removed]).
Related Links
* MMWR ([link removed]) main page provides access to MMWR Weekly and its companion publications
* CDC: Rates of Monkeypox Cases by Vaccination Status ([link removed]) web page (9/28/22)
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Keep up with influenza this season: use CDC’s FluView surveillance reports and Influenza Vaccination Dashboard, updated weekly
Influenza season has begun. CDC expects influenza activity, which is currently low, to increase in the coming weeks or months. CDC’s Weekly U.S. Influenza Surveillance Report, FluView ([link removed]), provides a valuable snapshot of influenza activity state-by-state.
Influenza Surveillance
For week 38, ending September 24, CDC's Weekly U.S. Influenza Surveillance Report, FluView ([link removed]) summary reports that, nationwide, 2.2% of patient visits reported through the Outpatient Influenza-Like Surveillance Network (ILINet) were due to respiratory illness that included fever plus a cough or sore throat (i.e., influenza-like illness [ILI]). Multiple respiratory viruses are co-circulating, and the relative contribution of influenza virus infection to ILI varies by location.
Influenza Vaccination Dashboard
CDC's Weekly Flu Vaccination Dashboard ([link removed]) data show that 71.4 million doses of influenza vaccine have been distributed in the United States through September 17, 2022. Vaccine manufacturers project that they will supply the United States with 173.5 million to 183.5 million doses for the 2022–23 season.
CDC recommends everyone age 6 months and older get annual influenza vaccination. Influenza and other vaccines (e.g., COVID-19 vaccines) may be given at the same visit, if needed. COVID-19 vaccination alone provides no protection from influenza or any other respiratory virus. To be listed as a provider by VaccineFinder, see the information at this website ([link removed]).
If you don’t provide influenza vaccine at your site, please strongly recommend vaccination and refer people to sites that do vaccinate. The American College of Physicians offers free Adult Vaccination Prescription Pads ([link removed]*drmh0y*_ga*ntqzmzi5mju1lje2nti4mji3nzy.*_ga_pm4f5hbgfq*mty2mju3nde3os4xntkums4xnjyyntc3mdmxlju5ljauma..&_ga=2.227238552.440966330.1662519116-543329255.1652822776&_gac=1.255840506.1661269092.cj0kcqjw9zgybhcearisaeuxitwuuaivyw-epaaozx8nprmbzpmo8erzuefz5wvnwp97z0cragqoeo8aambfealw_wcb) listing ACIP-recommended vaccines for adults to enable easy referral to vaccinating sites.
“Vaccines.gov” offers VaccineFinder ([link removed]), a service of Boston Children’s Hospital, to help people find influenza, COVID-19, and other vaccines for any age group.
Related Links
* CDC: Weekly National Flu Vaccination Dashboard ([link removed]) main page
* CDC: FluView ([link removed]) main page
* CDC: Influenza (Flu) ([link removed]) main page
* Immunize.org: free educational materials and patient handouts related to influenza ([link removed])
* Immunize.org: Vaccines: Influenza ([link removed]) main page
* Immunize.org: Ask the Experts: Influenza ([link removed]) main page
* Families Fighting Flu: Flu Resources for Healthcare Professionals ([link removed]) main page
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World Meningitis Day celebrated October 5. Are you advocating for adolescents to get MenB and second-dose MenACWY vaccine?
World Meningitis Day ([link removed]) is observed on October 5. World Meningitis Day is organized by the Confederation of Meningitis Organisations ([link removed]) (CoMO), an international organization that works to reduce the incidence and impact of meningitis.
To encourage sharing information about the signs and symptoms of meningitis, CoMo created infographics in 20 languages ([link removed]), all free to download and share.
Visit partner websites:
* National Meningitis Association ([link removed]), a parent-led nonprofit organization
* Meningitis B Action Project ([link removed]), ([link removed]) a parent-led nonprofit organization
* Meningitis Angels ([link removed]), a parent-led national nonprofit organization
Related Links
* CoMo: World Meningitis Day ([link removed]) Toolkit
* WHO: Global Roadmap to Defeat Meningitis by 2030 ([link removed]) web page
* WHO: Meningitis Disease ([link removed]) web page
* CDC: Meningococcal Vaccination ([link removed]) web page
* Immunize.org: Meningococcal ACWY Disease ([link removed]) web page
* Immunize.org: Meningococcal B Disease ([link removed]) web page
* Immunize.org: Give2MenACWY.org ([link removed]) website
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Invite your colleagues to subscribe to IZ Express so they don’t miss the latest immunization news!
Encourage your co-workers to subscribe to IZ Express ([link removed]) so they get all the news that matters to vaccinators in their own inbox each Wednesday. IZ Express ([link removed]), the free weekly e-newsletter produced by Immunize.org, succinctly summarizes each week’s important vaccine developments. IZ Express also features:
* Newly posted Vaccine Information Statements and their translations
* Educational materials from Immunize.org, CDC, AAP, and others
* Notices about online and in-person educational opportunities, many offering free continuing education credit
We appreciate you as a subscriber! Thank you for helping us spread the latest immunization news.
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Spotlight: “Ask the Experts” answers more than 1,200 questions on vaccines and vaccinations
In this week's Spotlight, we highlight the Ask the Experts ([link removed]) main page at Immunize.org ([link removed]).
Our Ask the Experts ([link removed]) main page offers more than a thousand timely questions on vaccines and vaccine administration answered by our experts. Topics include specific diseases and their vaccines as well as vaccine delivery guidance (e.g., administration, billing, documenting).
Immunize.org's Ask the Experts ([link removed]) main page leads you to 30 distinct web pages on a variety of topics with more than 1,200 common or challenging questions and answers (Q&As) about vaccines and their administration. Immunize.org's team of experts includes Kelly L. Moore, MD, MPH (team lead), Carolyn B. Bridges, MD, FACP, and Iyabode Beysolow, MD, MPH.
New and updated Ask the Experts Q&As are published in special editions of IZ Express five times per year. If you have a question that you think may be of interest to our readers, please send it to us using our online form ([link removed]).
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Journalists interview Immunize.org experts
Journalists seek out Immunize.org experts to help explain vaccines to the public and policy makers. We help the media understand and communicate the complex work vaccinators do. Here is a recent citation.
* Human Vaccines & Immunotherapeutics: Lessons Learned from 2 Years of Influenza Vaccinations in the UK and USA during the COVID-19 Pandemic as Respiratory Viruses Return ([link removed]) (9/26/22)
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Vaccines in the news
These recent articles convey the potential risks of vaccine-preventable diseases and the importance of vaccination.
* NBC: Less than 4% of Eligible People Have Gotten Updated COVID Booster Shots, 3 Weeks into the Rollout ([link removed]) (9/30/22)
* Wall Street Journal: Some Who Rushed to COVID-19 Vaccine Hold Off on Boosters ([link removed]) (9/22/22)
* Time: Here’s How Effective the Original Vaccines Are against Omicron ([link removed]) (9/22/22)
* STAT: Complexity of COVID Vaccine Program Leads to Concerns about Potential for Error ([link removed]) (9/14/22)
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Immunize.org Pages and Handouts
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Immunize.org updates its patient handout, "You're 16...We Recommend These Vaccines for You!"
Immunize.org and the Society for Adolescent Health and Medicine (SAHM) recently updated their patient handout, You're 16...We Recommend These Vaccines for You! ([link removed]). The sheet now indicates that:
* Human papillomavirus (HPV) vaccine may be started beginning at age 9 years
* The first dose of MenB vaccine should be administered at age 16–18 years
* COVID-19 vaccine is recommended for adolescents as a primary series plus booster doses
Related Links
* Immunize.org: Handouts: Adolescent Vaccination ([link removed]) main page
* Immunize.org: Parent Handouts ([link removed]) main page
* Immunize.org: Handouts ([link removed]) main page, sorted by topic
* Immunize.org: Handouts for Patients and Staff ([link removed])—an alphabetical list of more than 230 ready-to-print staff educational materials and patient handouts
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Recap: These updated Immunize.org educational materials and web pages for clinicians were released during August and September
In case you missed them during recent weeks, updates were made to these helpful materials:
Updated Influenza Materials and Web pages
* Ask the Experts: Influenza ([link removed])
* Influenza Vaccine Products for the 2022–2023 Influenza Season ([link removed])
* Standing Orders for Administering Influenza Vaccine to Children and Teens ([link removed])
* Standing Orders for Administering Influenza Vaccine to Adults ([link removed])
* Screening Checklist for Contraindications to Inactivated Injectable Influenza Vaccination ([link removed]), also available in Spanish ([link removed])
* Screening Checklist for Contraindications to Live Attenuated Intranasal Influenza Vaccination ([link removed]), also available in Spanish ([link removed])
* Influenza: Questions and Answers ([link removed])
* How to Administer Intramuscular and Intranasal Influenza Vaccines ([link removed])
* Influenza Vaccination of People with a History of Egg Allergy ([link removed])
* Guide for Determining the Number of Doses of Influenza Vaccine to Give to Children Age 6 Months through 8 Years ([link removed])
* Communicating the Benefits of Influenza Vaccine during COVID-19 ([link removed])
* Talking with Your Patients about Contraindications and Precautions to Influenza Vaccination ([link removed])
* Not Sure If You Can Get an Influenza Vaccine? ([link removed])
* Declination of Influenza Vaccination ([link removed])
* Don’t Take Chances with Your Family’s Health – Make Sure You All Get Vaccinated against Influenza Every Year! ([link removed])
Updated Printable Materials for Clinicians
* Checklist of Current Versions of U.S. COVID-19 Vaccination Guidance and Clinic Support Tools ([link removed]) (9/9/22)
* Administering Vaccines: Dose, Route, Site, and Needle Size ([link removed])
* Hepatitis B and Healthcare Personnel ([link removed])
* Zoster Vaccine: Immunize.org Answers Your Questions ([link removed])
Updated Web Pages
* Vaccines: COVID-19 ([link removed])
* Ask the Experts: COVID-19 ([link removed])
* Ask the Experts: Contraindications and Precautions ([link removed])
* Ask the Experts: Hib ([link removed])
* Ask the Experts: Billing and Reimbursement ([link removed])
* New! Vaccines: Monkeypox ([link removed])
Updated Printable Materials for Patients
* Vaccinations for Adults – You’re Never Too Old to Get Vaccinated! ([link removed])
* When Do Children and Teens Need Vaccinations? ([link removed])
* Vaccines Work! ([link removed])
Related Links
* Immunize.org: Handouts ([link removed]) main page to see educational materials sorted by category
* Immunize.org: Ask the Experts ([link removed]) main page to access more than 1,200 questions answered by Immunize.org experts
* Immunize.org: Clinic Tools ([link removed]) main page and its nine subtopics
* Immunize.org: Educational Materials for Patients and Staff ([link removed])—an alphabetical list of more than 230 ready-to-print staff educational materials and patient handouts
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Immunize.org updates “Pre-exposure Management for Healthcare Personnel with a Documented Hepatitis B Vaccine Series Who Have Not Had Post-vaccination Serologic Testing”
Immunize.org updated its Pre-exposure Management for Healthcare Personnel with a Documented Hepatitis B Vaccine Series Who Have Not Had Post-vaccination Serologic Testing ([link removed]) document in three ways:
* Adding the newest recommended hepatitis B vaccine option, PreHevbrio (VBI Vaccines)
* Clarifying considerations for healthcare personnel with documentation of a complete series of HepB vaccination but no documentation of protective levels of anti-HBs antibody
* Adding a link to the April 2022 CDC recommendation for routine HepB vaccination of all adults ([link removed]) 19 through 59 years old
Related Links
* Immunize.org: Vaccines: Hepatitis B ([link removed]) main page
* Immunize.org: Handouts: Healthcare Personnel ([link removed]) main page
* Immunize.org: Handouts for Patients and Staff ([link removed]) main page, where you can sort materials by topic, vaccine, or language
* Immunize.org: Educational Materials for Patients and Staff ([link removed])—an alphabetical listing of more than 230 ready-to-print staff educational materials and patient handouts
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Vaccine Information Statements
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Recap: These new VISs and VIS translations were released during August and September
In August, CDC released an update to the Smallpox/Monkeypox Vaccine VIS ([link removed]).
Here are recent languages of VIS translations posted during August and September:
* Haitian Creole ([link removed]) – Multi pediatric vaccines and Smallpox/monkeypox vaccine
* Portuguese ([link removed] – Multi pediatric vaccines and Smallpox/monkeypox vaccine
* Turkish ([link removed]) – Adenovirus, Anthrax, Japanese encephalitis, Multi pediatric vaccines, PCV, Yellow fever, and Zoster
Additionally, two handouts related to VISs were updated:
* Dates of Current Vaccine Information Statements (VISs) ([link removed])
* You Must Provide Patients with Vaccine Information Statements (VISs) – It's Federal Law! ([link removed])
Related Links
* Immunize.org: Vaccine Information Statement ([link removed]) main page for VISs in 47 languages
* Immunize.org: Dates of Current Vaccine Information Statements ([link removed]) (PDF)
* CDC: What's New with VISs ([link removed]) web page
* CDC: Current VISs ([link removed]) web page
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Featured Resources
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Explore the www.Give2MenACWY.org website to increase coverage for the MenACWY booster and other adolescent vaccinations
Immunize.org's www.Give2MenACWY.org ([link removed]) website promotes the importance of adolescent vaccination, including the recommended MenACWY vaccine booster dose at age 16. Many teens are behind on vaccines because of the pandemic, so vaccination is more important than ever.
Materials on this colorful website for healthcare professionals incorporate the 2020 ACIP meningococcal vaccine recommendations ([link removed]) and coverage statistics from CDC’s National Immunization Survey–Teen (NIS–Teen). One particularly popular resource on the site is the updated Algorithm for MenACWY Immunization in Adolescents 11 through 18 Years of Age ([link removed]).
The website is divided into five easy-to-access sections:
* Vaccinate Teens ([link removed]) – Teen vaccination schedules and tips for improving vaccination rates
* Give 2 Doses ([link removed]) – Tools to help improve second dose coverage of MenACWY vaccine
* 16-Year-Old Visit ([link removed]) – Resources to help providers and patients remember the important vaccines recommended for 16-year-olds
* Tools for Providers ([link removed]) – Tools to explain meningococcal ACWY vaccine recommendations and improve coverage for all adolescent vaccines
* Resources ([link removed]) – Links to print materials ([link removed]), organizations ([link removed]) involved in adolescent vaccination, personal stories ([link removed]) about the importance of vaccination, and other resources ([link removed]) of interest
The site also categorizes materials ([link removed]) according to whether they are primarily of interest to providers, to adolescents, or to parents.
Visit Give2MenACWY.org ([link removed]) and enjoy browsing (and deploying) its bountiful resources.
Related Links
* Give2MenACWY.org ([link removed]) website
* Algorithm for MenACWY Immunization in Adolescents 11–18 Years of Age ([link removed])
* MenACWY: You're Not Done If You Give Just One: Give 2 Doses to Strengthen Protection ([link removed])
* Recommending MenACWY: What to Say and How to Say It ([link removed])
* Top 10 Ways to Improve Adolescent Immunization Rates ([link removed])
* Developing an Immunization Culture in Your Office ([link removed])
* Know Your Rates: Measuring Immunization Success in Your Practice ([link removed])
* You're 16: We Recommend These Vaccines for You ([link removed])
* Dear Colleague Letter: 16-Year-Old Patients: Make Sure They Receive Their Annual Well Visit and Vaccinations ([link removed]) – signed by six medical societies
* Ask the Experts: Meningococcal ACWY ([link removed])
* CDC: 2020 ACIP Meningococcal Vaccine Recommendations ([link removed])
* CDC: National, Regional, State, and Selected Local Area Vaccination Coverage among Adolescents Aged 13–17 Years — United States, 2020 ([link removed])
* CDC: Adolescent Vaccination Coverage in the U.S. ([link removed])
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Notable Publications
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“Association between Aluminum Exposure from Vaccines before Age 24 Months and Persistent Asthma at Age 24 to 59 Months” published in Academic Pediatrics
In its article-in-press version, Academic Pediatrics released Association between Aluminum Exposure from Vaccines before Age 24 Months and Persistent Asthma at Age 24 to 59 Months ([link removed]). A portion of the article, written by Vaccine Safety Datalink (VSD) investigators (including CDC), appears below.
In a large observational study, a positive association was found between vaccine-related aluminum exposure and persistent asthma. While recognizing the small effect sizes identified and the potential for unmeasured confounding, additional investigation of this hypothesis appears warranted.
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NIH-funded study links COVID-19 vaccination and temporary increase in menstrual cycle length
On September 27, NIH announced results of an international study, linking a temporary increase of less than 1 day in menstrual cycle length with COVID-19 vaccination. The study was published in BMJ Medicine, and titled Association between Menstrual Cycle Length and COVID-19 Vaccination: Global, Retrospective Cohort Study of Prospectively Collected Data ([link removed]). The first paragraph of the press release ([link removed]) appears below.
A large international study has confirmed the findings of a previous U.S. study that linked COVID-19 vaccination with an average increase in menstrual cycle length of less than one day. The increase was not associated with any change in the number of days of menses (days of bleeding). Funded by the National Institutes of Health, the new study included data from nearly 20,000 people from Canada, the United Kingdom, the United States, Europe and other parts of the world who received any of nine different vaccines. For most study participants, the increase resolved in the cycle following vaccination.
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"Estimation of COVID-19 mRNA Vaccine Effectiveness against Medically Attended COVID-19 in Pregnancy during Periods of Delta and Omicron Variant Predominance in the United States" published in JAMA Network
JAMA Network published Estimation of COVID-19 mRNA Vaccine Effectiveness against Medically Attended COVID-19 in Pregnancy during Periods of Delta and Omicron Variant Predominance in the United States ([link removed]) on September 26. The conclusions and relevance section appears below.
In this study, maternal mRNA COVID-19 vaccination, including booster dose, was associated with protection against medically attended COVID-19. VE [vaccine effectiveness] estimates were higher against COVID-19–associated hospitalization than ED/UC [emergency department or urgent care] visits and lower against the Omicron variant than the Delta variant. Protection waned over time, particularly during Omicron predominance.
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“Widespread Hepatitis A Outbreaks Associated with Person-to-Person Transmission—United States, 2016–2020” published in MMWR
CDC published Widespread Hepatitis A Outbreaks Associated with Person-to-Person Transmission—United States, 2016–2020 ([link removed]) in the September 30 issue of MMWR ([link removed]). A portion of the summary appears below.
Hepatitis A epidemiology in the United States has shifted as a result of recent and ongoing outbreaks associated with person-to-person transmission. During August 1, 2016–December 31, 2020, 33 states reported hepatitis A outbreaks involving approximately 37,500 cases. Among cases with available information, 56% of persons reported drug use, 14% reported homelessness, and 61% were hospitalized; 380 outbreak-associated deaths were reported. . . .
Increased hepatitis A vaccination coverage, through implementation of nontraditional vaccination strategies to reach disproportionately affected populations, along with improved universal and catch-up childhood vaccination, will be necessary to respond to the current hepatitis A outbreaks and prevent similar outbreaks in the future.
Access the MMWR article in HTML ([link removed]) or PDF ([link removed]).
Related Links
* MMWR ([link removed]) main page provides access to MMWR Weekly and its companion publications
* ACIP: Recommendations ([link removed]) for the prevention of hepatitis A
* Immunize.org: Vaccines: Hepatitis A ([link removed])
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“Effectiveness of a Second COVID-19 Vaccine Booster Dose against Infection, Hospitalization, or Death among Nursing Home Residents—19 States, March 29–July 25, 2022” published in MMWR
CDC published Effectiveness of a Second COVID-19 Vaccine Booster Dose against Infection, Hospitalization, or Death among Nursing Home Residents—19 States, March 29–July 25, 2022 ([link removed]) in the September 30 issue of MMWR ([link removed]) . A portion of the summary appears below.
In a large cohort of nursing home residents, receipt of a second mRNA COVID-19 booster dose during circulation of SARS-CoV-2 Omicron subvariants was 74% effective at 60 days against severe COVID-19–related outcomes (including hospitalization or death) and 90% against death alone compared with receipt of a single booster dose. . . .
Efforts should be made to ensure that nursing home residents remain up to date with recommended booster doses of COVID-19 vaccines.
Access the MMWR article in HTML ([link removed]) or PDF ([link removed]) .
Related Link
* MMWR ([link removed]) main page provides access to MMWR Weekly and its companion publications
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Upcoming Events
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Virtual: National Foundation for Infectious Diseases hosts "Clinical Vaccinology Course" on November 16–18; CME/CNE available
The National Foundation of Infectious Diseases ([link removed]) (NFID) Clinical Vaccinology Course ([link removed]) will be held online November 16–18. This 3-day online course focuses on new developments and issues related to use of vaccines. Expert faculty provide the latest information on vaccines, including updated recommendations for vaccinations across the lifespan, and innovative and practical strategies for ensuring timely and appropriate vaccination.
Continuing medical education (CME) and continuing nursing education (CNE) ([link removed]) credit will be offered.
Register for the online course ([link removed]) ($750 fee).
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On-demand: CDC’s “The Pink Book” chapter webinars on vaccine-preventable diseases and best practices roll out weekly. HPV webinar now available, with CE.
CDC continues its free 19-part pre-recorded webinar series ([link removed]) to provide a chapter-by-chapter overview of the 14th edition of Epidemiology and Prevention of Vaccine-Preventable Diseases ([link removed]) (also known as "The Pink Book").
The webinar on human papillomavirus (HPV) was released on October 4. Fourteen webinars are now available on demand. Additional webinars will be released weekly, concluding on November 1, 2022.
No registration is required to view the sessions. Information and program details are available on CDC's Pink Book Webinars ([link removed]) series web page.
CME, CNE, CPE, and CEU credits are available for each event. Questions about the material can be submitted to [email protected].
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For more upcoming events, visit our Calendar of Events ([link removed]).
Editorial Information
Editor-in-Chief
Kelly L. Moore, MD, MPH
Managing Editor
John D. Grabenstein, RPh, PhD
Associate Editor
Sharon G. Humiston, MD, MPH
Writer/Publication Coordinator
Taryn Chapman, MS
Courtnay Londo, MA
Style and Copy Editor
Marian Deegan, JD
Web Edition Managers
Arkady Shakhnovich
Jermaine Royes
Contributing Writer
Laurel H. Wood, MPA
Technical Reviewer
Kayla Ohlde
About IZ Express
Immunize.org welcomes redistribution of this issue of IZ Express or selected articles. When you do so, please add a note that Immunize.org is the source of the material and provide a link to this issue ([link removed]).
IZ Express is supported in part by Grant No. 1NH23IP922654 from the National Center for Immunization and Respiratory Diseases, CDC. Its contents are solely the responsibility of Immunize.org and do not necessarily represent the official views of CDC.
IZ Express Disclaimer ([link removed])
ISSN: 2771-8085
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Issue 1,656: October 5, 2022
Top Stories
* View your state’s stats. CDC’s interactive web tool updated with 2021 Behavioral Risk Factor Surveillance System (BRFSS) data on adult vaccination rates.
* “Cholera Vaccine: Recommendations of the Advisory Committee on Immunization Practices, 2022” published in MMWR Recommendations and Reports
* "Incidence of Monkeypox among Unvaccinated Persons Compared with Persons Receiving ≥1 Jynneos Vaccine Dose—32 U.S. Jurisdictions, July 31–September 3, 2022" published in MMWR Early Release
* Keep up with influenza this season: use CDC’s FluView surveillance reports and Influenza Vaccination Dashboard, updated weekly
* World Meningitis Day celebrated October 5. Are you advocating for adolescents to get MenB and second-dose MenACWY vaccine?
* Invite your colleagues to subscribe to IZ Express so they don’t miss the latest immunization news!
* Spotlight: “Ask the Experts” answers more than 1,200 questions on vaccines and vaccinations
* Journalists interview Immunize.org experts
* Vaccines in the news
Immunize.org Pages and Handouts
* Immunize.org updates its patient handout, "You're 16...We Recommend These Vaccines for You!"
* Recap: These updated Immunize.org educational materials and web pages for clinicians were released during August and September
* Immunize.org updates “Pre-exposure Management for Healthcare Personnel with a Documented Hepatitis B Vaccine Series Who Have Not Had Post-vaccination Serologic Testing”
Vaccine Information Statements
* Recap: These new VISs and VIS translations were released during August and September
Featured Resources
* Explore the www.Give2MenACWY.org website to increase coverage for the MenACWY booster and other adolescent vaccinations
Notable Publications
* “Association between Aluminum Exposure from Vaccines before Age 24 Months and Persistent Asthma at Age 24 to 59 Months” published in Academic Pediatrics
* NIH-funded study links COVID-19 vaccination and temporary increase in menstrual cycle length
* "Estimation of COVID-19 mRNA Vaccine Effectiveness against Medically Attended COVID-19 in Pregnancy during Periods of Delta and Omicron Variant Predominance in the United States" published in JAMA Network
* “Widespread Hepatitis A Outbreaks Associated with Person-to-Person Transmission—United States, 2016–2020” published in MMWR
* “Effectiveness of a Second COVID-19 Vaccine Booster Dose against Infection, Hospitalization, or Death among Nursing Home Residents—19 States, March 29–July 25, 2022” published in MMWR
Upcoming Events
* Virtual: National Foundation for Infectious Diseases hosts "Clinical Vaccinology Course" on November 16–18; CME/CNE available
* On-demand: CDC’s “The Pink Book” chapter webinars on vaccine-preventable diseases and best practices roll out weekly. HPV webinar now available, with CE.
Editorial Information
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Top Stories
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View your state’s stats. CDC’s interactive web tool updated with 2021 Behavioral Risk Factor Surveillance System (BRFSS) data on adult vaccination rates.
Behavioral Risk Factor Surveillance System (BRFSS) ([link removed]) data for 2021 are now available through CDC’s easy-to-use web-based tool. Topics include self-reported use of preventive services, including adult vaccination. Updated annually, the prevalence and trends tool ([link removed]) offers fast access to a large portion of the 2021 data set and can be a helpful resource to reporters, vaccine advocates, students, public-health officials, and decision-makers. The tool is updated every year.
BRFSS prevalence and trends data are available for all states and territories. An example map showing adults aged 65+ vaccinated against influenza within the past year appears below.
Related Links
* CDC Media Release: CDC Releases Data on Chronic Diseases and Related Risk Factors ([link removed]) (9/27/22)
* CDC: BRFSS Prevalence & Trends Data ([link removed])
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“Cholera Vaccine: Recommendations of the Advisory Committee on Immunization Practices, 2022” published in MMWR Recommendations and Reports
CDC published Cholera Vaccine: Recommendations of the Advisory Committee on Immunization Practices, 2022 ([link removed]) in the September 30 issue of MMWR Recommendations and Reports. A portion of the summary appears below.
Cholera is rare in the United States, but cases occur among travelers to countries where cholera is endemic or epidemic and associated with unsafe water and inadequate sanitation. Travelers might be at increased risk for poor outcomes from cholera if they cannot readily access medical services or if they have a medical condition that would be worsened by dehydration, such as cardiovascular or kidney disease. This report describes previously published ACIP recommendations about use of CVD 103-HgR for adults aged 18–64 years and introduces a new recommendation for use in children and adolescents aged 2–17 years. ACIP recommends CVD 103-HgR, the only cholera vaccine licensed for use in the United States, for prevention of cholera among travelers aged 2–64 years to an area with active cholera transmission. Health care providers can use these guidelines to develop the pretravel consultation for persons traveling to areas with active cholera transmission.
Access the MMWR article in HTML ([link removed]) or PDF ([link removed]).
Related Links
* Emergent Biosolutions: Vaxchora Package Insert ([link removed])
* FDA: Product Approval – Cholera ([link removed])
* Immunize.org: Package Inserts and FDA Product Approvals ([link removed]) web page
* Immunize.org: ACIP Recommendations ([link removed]) web page
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"Incidence of Monkeypox among Unvaccinated Persons Compared with Persons Receiving ≥1 Jynneos Vaccine Dose—32 U.S. Jurisdictions, July 31–September 3, 2022" published in MMWR Early Release
CDC published Incidence of Monkeypox among Unvaccinated Persons Compared with Persons Receiving ≥1 Jynneos Vaccine Dose—32 U.S. Jurisdictions, July 31–September 3, 2022 ([link removed]) in the September 30 issue of MMWR Early Release. The summary appears below.
Across 32 U.S. jurisdictions, among males aged 18–49 years eligible for JYNNEOS vaccination, monkeypox incidence was 14 times as high among unvaccinated males compared with those who had received a first vaccine dose ≥14 days earlier. . . .
These early findings suggest that a single JYNNEOS dose provides some protection against monkeypox infection. The degree and durability of such protection is unknown, and it is recommended that persons who are eligible for monkeypox vaccination receive the complete 2-dose series.
Access the MMWR article in HTML ([link removed]).
Related Links
* MMWR ([link removed]) main page provides access to MMWR Weekly and its companion publications
* CDC: Rates of Monkeypox Cases by Vaccination Status ([link removed]) web page (9/28/22)
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Keep up with influenza this season: use CDC’s FluView surveillance reports and Influenza Vaccination Dashboard, updated weekly
Influenza season has begun. CDC expects influenza activity, which is currently low, to increase in the coming weeks or months. CDC’s Weekly U.S. Influenza Surveillance Report, FluView ([link removed]), provides a valuable snapshot of influenza activity state-by-state.
Influenza Surveillance
For week 38, ending September 24, CDC's Weekly U.S. Influenza Surveillance Report, FluView ([link removed]) summary reports that, nationwide, 2.2% of patient visits reported through the Outpatient Influenza-Like Surveillance Network (ILINet) were due to respiratory illness that included fever plus a cough or sore throat (i.e., influenza-like illness [ILI]). Multiple respiratory viruses are co-circulating, and the relative contribution of influenza virus infection to ILI varies by location.
Influenza Vaccination Dashboard
CDC's Weekly Flu Vaccination Dashboard ([link removed]) data show that 71.4 million doses of influenza vaccine have been distributed in the United States through September 17, 2022. Vaccine manufacturers project that they will supply the United States with 173.5 million to 183.5 million doses for the 2022–23 season.
CDC recommends everyone age 6 months and older get annual influenza vaccination. Influenza and other vaccines (e.g., COVID-19 vaccines) may be given at the same visit, if needed. COVID-19 vaccination alone provides no protection from influenza or any other respiratory virus. To be listed as a provider by VaccineFinder, see the information at this website ([link removed]).
If you don’t provide influenza vaccine at your site, please strongly recommend vaccination and refer people to sites that do vaccinate. The American College of Physicians offers free Adult Vaccination Prescription Pads ([link removed]*drmh0y*_ga*ntqzmzi5mju1lje2nti4mji3nzy.*_ga_pm4f5hbgfq*mty2mju3nde3os4xntkums4xnjyyntc3mdmxlju5ljauma..&_ga=2.227238552.440966330.1662519116-543329255.1652822776&_gac=1.255840506.1661269092.cj0kcqjw9zgybhcearisaeuxitwuuaivyw-epaaozx8nprmbzpmo8erzuefz5wvnwp97z0cragqoeo8aambfealw_wcb) listing ACIP-recommended vaccines for adults to enable easy referral to vaccinating sites.
“Vaccines.gov” offers VaccineFinder ([link removed]), a service of Boston Children’s Hospital, to help people find influenza, COVID-19, and other vaccines for any age group.
Related Links
* CDC: Weekly National Flu Vaccination Dashboard ([link removed]) main page
* CDC: FluView ([link removed]) main page
* CDC: Influenza (Flu) ([link removed]) main page
* Immunize.org: free educational materials and patient handouts related to influenza ([link removed])
* Immunize.org: Vaccines: Influenza ([link removed]) main page
* Immunize.org: Ask the Experts: Influenza ([link removed]) main page
* Families Fighting Flu: Flu Resources for Healthcare Professionals ([link removed]) main page
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World Meningitis Day celebrated October 5. Are you advocating for adolescents to get MenB and second-dose MenACWY vaccine?
World Meningitis Day ([link removed]) is observed on October 5. World Meningitis Day is organized by the Confederation of Meningitis Organisations ([link removed]) (CoMO), an international organization that works to reduce the incidence and impact of meningitis.
To encourage sharing information about the signs and symptoms of meningitis, CoMo created infographics in 20 languages ([link removed]), all free to download and share.
Visit partner websites:
* National Meningitis Association ([link removed]), a parent-led nonprofit organization
* Meningitis B Action Project ([link removed]), ([link removed]) a parent-led nonprofit organization
* Meningitis Angels ([link removed]), a parent-led national nonprofit organization
Related Links
* CoMo: World Meningitis Day ([link removed]) Toolkit
* WHO: Global Roadmap to Defeat Meningitis by 2030 ([link removed]) web page
* WHO: Meningitis Disease ([link removed]) web page
* CDC: Meningococcal Vaccination ([link removed]) web page
* Immunize.org: Meningococcal ACWY Disease ([link removed]) web page
* Immunize.org: Meningococcal B Disease ([link removed]) web page
* Immunize.org: Give2MenACWY.org ([link removed]) website
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Invite your colleagues to subscribe to IZ Express so they don’t miss the latest immunization news!
Encourage your co-workers to subscribe to IZ Express ([link removed]) so they get all the news that matters to vaccinators in their own inbox each Wednesday. IZ Express ([link removed]), the free weekly e-newsletter produced by Immunize.org, succinctly summarizes each week’s important vaccine developments. IZ Express also features:
* Newly posted Vaccine Information Statements and their translations
* Educational materials from Immunize.org, CDC, AAP, and others
* Notices about online and in-person educational opportunities, many offering free continuing education credit
We appreciate you as a subscriber! Thank you for helping us spread the latest immunization news.
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Spotlight: “Ask the Experts” answers more than 1,200 questions on vaccines and vaccinations
In this week's Spotlight, we highlight the Ask the Experts ([link removed]) main page at Immunize.org ([link removed]).
Our Ask the Experts ([link removed]) main page offers more than a thousand timely questions on vaccines and vaccine administration answered by our experts. Topics include specific diseases and their vaccines as well as vaccine delivery guidance (e.g., administration, billing, documenting).
Immunize.org's Ask the Experts ([link removed]) main page leads you to 30 distinct web pages on a variety of topics with more than 1,200 common or challenging questions and answers (Q&As) about vaccines and their administration. Immunize.org's team of experts includes Kelly L. Moore, MD, MPH (team lead), Carolyn B. Bridges, MD, FACP, and Iyabode Beysolow, MD, MPH.
New and updated Ask the Experts Q&As are published in special editions of IZ Express five times per year. If you have a question that you think may be of interest to our readers, please send it to us using our online form ([link removed]).
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Journalists interview Immunize.org experts
Journalists seek out Immunize.org experts to help explain vaccines to the public and policy makers. We help the media understand and communicate the complex work vaccinators do. Here is a recent citation.
* Human Vaccines & Immunotherapeutics: Lessons Learned from 2 Years of Influenza Vaccinations in the UK and USA during the COVID-19 Pandemic as Respiratory Viruses Return ([link removed]) (9/26/22)
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Vaccines in the news
These recent articles convey the potential risks of vaccine-preventable diseases and the importance of vaccination.
* NBC: Less than 4% of Eligible People Have Gotten Updated COVID Booster Shots, 3 Weeks into the Rollout ([link removed]) (9/30/22)
* Wall Street Journal: Some Who Rushed to COVID-19 Vaccine Hold Off on Boosters ([link removed]) (9/22/22)
* Time: Here’s How Effective the Original Vaccines Are against Omicron ([link removed]) (9/22/22)
* STAT: Complexity of COVID Vaccine Program Leads to Concerns about Potential for Error ([link removed]) (9/14/22)
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Immunize.org Pages and Handouts
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Immunize.org updates its patient handout, "You're 16...We Recommend These Vaccines for You!"
Immunize.org and the Society for Adolescent Health and Medicine (SAHM) recently updated their patient handout, You're 16...We Recommend These Vaccines for You! ([link removed]). The sheet now indicates that:
* Human papillomavirus (HPV) vaccine may be started beginning at age 9 years
* The first dose of MenB vaccine should be administered at age 16–18 years
* COVID-19 vaccine is recommended for adolescents as a primary series plus booster doses
Related Links
* Immunize.org: Handouts: Adolescent Vaccination ([link removed]) main page
* Immunize.org: Parent Handouts ([link removed]) main page
* Immunize.org: Handouts ([link removed]) main page, sorted by topic
* Immunize.org: Handouts for Patients and Staff ([link removed])—an alphabetical list of more than 230 ready-to-print staff educational materials and patient handouts
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Recap: These updated Immunize.org educational materials and web pages for clinicians were released during August and September
In case you missed them during recent weeks, updates were made to these helpful materials:
Updated Influenza Materials and Web pages
* Ask the Experts: Influenza ([link removed])
* Influenza Vaccine Products for the 2022–2023 Influenza Season ([link removed])
* Standing Orders for Administering Influenza Vaccine to Children and Teens ([link removed])
* Standing Orders for Administering Influenza Vaccine to Adults ([link removed])
* Screening Checklist for Contraindications to Inactivated Injectable Influenza Vaccination ([link removed]), also available in Spanish ([link removed])
* Screening Checklist for Contraindications to Live Attenuated Intranasal Influenza Vaccination ([link removed]), also available in Spanish ([link removed])
* Influenza: Questions and Answers ([link removed])
* How to Administer Intramuscular and Intranasal Influenza Vaccines ([link removed])
* Influenza Vaccination of People with a History of Egg Allergy ([link removed])
* Guide for Determining the Number of Doses of Influenza Vaccine to Give to Children Age 6 Months through 8 Years ([link removed])
* Communicating the Benefits of Influenza Vaccine during COVID-19 ([link removed])
* Talking with Your Patients about Contraindications and Precautions to Influenza Vaccination ([link removed])
* Not Sure If You Can Get an Influenza Vaccine? ([link removed])
* Declination of Influenza Vaccination ([link removed])
* Don’t Take Chances with Your Family’s Health – Make Sure You All Get Vaccinated against Influenza Every Year! ([link removed])
Updated Printable Materials for Clinicians
* Checklist of Current Versions of U.S. COVID-19 Vaccination Guidance and Clinic Support Tools ([link removed]) (9/9/22)
* Administering Vaccines: Dose, Route, Site, and Needle Size ([link removed])
* Hepatitis B and Healthcare Personnel ([link removed])
* Zoster Vaccine: Immunize.org Answers Your Questions ([link removed])
Updated Web Pages
* Vaccines: COVID-19 ([link removed])
* Ask the Experts: COVID-19 ([link removed])
* Ask the Experts: Contraindications and Precautions ([link removed])
* Ask the Experts: Hib ([link removed])
* Ask the Experts: Billing and Reimbursement ([link removed])
* New! Vaccines: Monkeypox ([link removed])
Updated Printable Materials for Patients
* Vaccinations for Adults – You’re Never Too Old to Get Vaccinated! ([link removed])
* When Do Children and Teens Need Vaccinations? ([link removed])
* Vaccines Work! ([link removed])
Related Links
* Immunize.org: Handouts ([link removed]) main page to see educational materials sorted by category
* Immunize.org: Ask the Experts ([link removed]) main page to access more than 1,200 questions answered by Immunize.org experts
* Immunize.org: Clinic Tools ([link removed]) main page and its nine subtopics
* Immunize.org: Educational Materials for Patients and Staff ([link removed])—an alphabetical list of more than 230 ready-to-print staff educational materials and patient handouts
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Immunize.org updates “Pre-exposure Management for Healthcare Personnel with a Documented Hepatitis B Vaccine Series Who Have Not Had Post-vaccination Serologic Testing”
Immunize.org updated its Pre-exposure Management for Healthcare Personnel with a Documented Hepatitis B Vaccine Series Who Have Not Had Post-vaccination Serologic Testing ([link removed]) document in three ways:
* Adding the newest recommended hepatitis B vaccine option, PreHevbrio (VBI Vaccines)
* Clarifying considerations for healthcare personnel with documentation of a complete series of HepB vaccination but no documentation of protective levels of anti-HBs antibody
* Adding a link to the April 2022 CDC recommendation for routine HepB vaccination of all adults ([link removed]) 19 through 59 years old
Related Links
* Immunize.org: Vaccines: Hepatitis B ([link removed]) main page
* Immunize.org: Handouts: Healthcare Personnel ([link removed]) main page
* Immunize.org: Handouts for Patients and Staff ([link removed]) main page, where you can sort materials by topic, vaccine, or language
* Immunize.org: Educational Materials for Patients and Staff ([link removed])—an alphabetical listing of more than 230 ready-to-print staff educational materials and patient handouts
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Vaccine Information Statements
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Recap: These new VISs and VIS translations were released during August and September
In August, CDC released an update to the Smallpox/Monkeypox Vaccine VIS ([link removed]).
Here are recent languages of VIS translations posted during August and September:
* Haitian Creole ([link removed]) – Multi pediatric vaccines and Smallpox/monkeypox vaccine
* Portuguese ([link removed] – Multi pediatric vaccines and Smallpox/monkeypox vaccine
* Turkish ([link removed]) – Adenovirus, Anthrax, Japanese encephalitis, Multi pediatric vaccines, PCV, Yellow fever, and Zoster
Additionally, two handouts related to VISs were updated:
* Dates of Current Vaccine Information Statements (VISs) ([link removed])
* You Must Provide Patients with Vaccine Information Statements (VISs) – It's Federal Law! ([link removed])
Related Links
* Immunize.org: Vaccine Information Statement ([link removed]) main page for VISs in 47 languages
* Immunize.org: Dates of Current Vaccine Information Statements ([link removed]) (PDF)
* CDC: What's New with VISs ([link removed]) web page
* CDC: Current VISs ([link removed]) web page
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Featured Resources
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Explore the www.Give2MenACWY.org website to increase coverage for the MenACWY booster and other adolescent vaccinations
Immunize.org's www.Give2MenACWY.org ([link removed]) website promotes the importance of adolescent vaccination, including the recommended MenACWY vaccine booster dose at age 16. Many teens are behind on vaccines because of the pandemic, so vaccination is more important than ever.
Materials on this colorful website for healthcare professionals incorporate the 2020 ACIP meningococcal vaccine recommendations ([link removed]) and coverage statistics from CDC’s National Immunization Survey–Teen (NIS–Teen). One particularly popular resource on the site is the updated Algorithm for MenACWY Immunization in Adolescents 11 through 18 Years of Age ([link removed]).
The website is divided into five easy-to-access sections:
* Vaccinate Teens ([link removed]) – Teen vaccination schedules and tips for improving vaccination rates
* Give 2 Doses ([link removed]) – Tools to help improve second dose coverage of MenACWY vaccine
* 16-Year-Old Visit ([link removed]) – Resources to help providers and patients remember the important vaccines recommended for 16-year-olds
* Tools for Providers ([link removed]) – Tools to explain meningococcal ACWY vaccine recommendations and improve coverage for all adolescent vaccines
* Resources ([link removed]) – Links to print materials ([link removed]), organizations ([link removed]) involved in adolescent vaccination, personal stories ([link removed]) about the importance of vaccination, and other resources ([link removed]) of interest
The site also categorizes materials ([link removed]) according to whether they are primarily of interest to providers, to adolescents, or to parents.
Visit Give2MenACWY.org ([link removed]) and enjoy browsing (and deploying) its bountiful resources.
Related Links
* Give2MenACWY.org ([link removed]) website
* Algorithm for MenACWY Immunization in Adolescents 11–18 Years of Age ([link removed])
* MenACWY: You're Not Done If You Give Just One: Give 2 Doses to Strengthen Protection ([link removed])
* Recommending MenACWY: What to Say and How to Say It ([link removed])
* Top 10 Ways to Improve Adolescent Immunization Rates ([link removed])
* Developing an Immunization Culture in Your Office ([link removed])
* Know Your Rates: Measuring Immunization Success in Your Practice ([link removed])
* You're 16: We Recommend These Vaccines for You ([link removed])
* Dear Colleague Letter: 16-Year-Old Patients: Make Sure They Receive Their Annual Well Visit and Vaccinations ([link removed]) – signed by six medical societies
* Ask the Experts: Meningococcal ACWY ([link removed])
* CDC: 2020 ACIP Meningococcal Vaccine Recommendations ([link removed])
* CDC: National, Regional, State, and Selected Local Area Vaccination Coverage among Adolescents Aged 13–17 Years — United States, 2020 ([link removed])
* CDC: Adolescent Vaccination Coverage in the U.S. ([link removed])
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Notable Publications
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“Association between Aluminum Exposure from Vaccines before Age 24 Months and Persistent Asthma at Age 24 to 59 Months” published in Academic Pediatrics
In its article-in-press version, Academic Pediatrics released Association between Aluminum Exposure from Vaccines before Age 24 Months and Persistent Asthma at Age 24 to 59 Months ([link removed]). A portion of the article, written by Vaccine Safety Datalink (VSD) investigators (including CDC), appears below.
In a large observational study, a positive association was found between vaccine-related aluminum exposure and persistent asthma. While recognizing the small effect sizes identified and the potential for unmeasured confounding, additional investigation of this hypothesis appears warranted.
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NIH-funded study links COVID-19 vaccination and temporary increase in menstrual cycle length
On September 27, NIH announced results of an international study, linking a temporary increase of less than 1 day in menstrual cycle length with COVID-19 vaccination. The study was published in BMJ Medicine, and titled Association between Menstrual Cycle Length and COVID-19 Vaccination: Global, Retrospective Cohort Study of Prospectively Collected Data ([link removed]). The first paragraph of the press release ([link removed]) appears below.
A large international study has confirmed the findings of a previous U.S. study that linked COVID-19 vaccination with an average increase in menstrual cycle length of less than one day. The increase was not associated with any change in the number of days of menses (days of bleeding). Funded by the National Institutes of Health, the new study included data from nearly 20,000 people from Canada, the United Kingdom, the United States, Europe and other parts of the world who received any of nine different vaccines. For most study participants, the increase resolved in the cycle following vaccination.
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"Estimation of COVID-19 mRNA Vaccine Effectiveness against Medically Attended COVID-19 in Pregnancy during Periods of Delta and Omicron Variant Predominance in the United States" published in JAMA Network
JAMA Network published Estimation of COVID-19 mRNA Vaccine Effectiveness against Medically Attended COVID-19 in Pregnancy during Periods of Delta and Omicron Variant Predominance in the United States ([link removed]) on September 26. The conclusions and relevance section appears below.
In this study, maternal mRNA COVID-19 vaccination, including booster dose, was associated with protection against medically attended COVID-19. VE [vaccine effectiveness] estimates were higher against COVID-19–associated hospitalization than ED/UC [emergency department or urgent care] visits and lower against the Omicron variant than the Delta variant. Protection waned over time, particularly during Omicron predominance.
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“Widespread Hepatitis A Outbreaks Associated with Person-to-Person Transmission—United States, 2016–2020” published in MMWR
CDC published Widespread Hepatitis A Outbreaks Associated with Person-to-Person Transmission—United States, 2016–2020 ([link removed]) in the September 30 issue of MMWR ([link removed]). A portion of the summary appears below.
Hepatitis A epidemiology in the United States has shifted as a result of recent and ongoing outbreaks associated with person-to-person transmission. During August 1, 2016–December 31, 2020, 33 states reported hepatitis A outbreaks involving approximately 37,500 cases. Among cases with available information, 56% of persons reported drug use, 14% reported homelessness, and 61% were hospitalized; 380 outbreak-associated deaths were reported. . . .
Increased hepatitis A vaccination coverage, through implementation of nontraditional vaccination strategies to reach disproportionately affected populations, along with improved universal and catch-up childhood vaccination, will be necessary to respond to the current hepatitis A outbreaks and prevent similar outbreaks in the future.
Access the MMWR article in HTML ([link removed]) or PDF ([link removed]).
Related Links
* MMWR ([link removed]) main page provides access to MMWR Weekly and its companion publications
* ACIP: Recommendations ([link removed]) for the prevention of hepatitis A
* Immunize.org: Vaccines: Hepatitis A ([link removed])
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“Effectiveness of a Second COVID-19 Vaccine Booster Dose against Infection, Hospitalization, or Death among Nursing Home Residents—19 States, March 29–July 25, 2022” published in MMWR
CDC published Effectiveness of a Second COVID-19 Vaccine Booster Dose against Infection, Hospitalization, or Death among Nursing Home Residents—19 States, March 29–July 25, 2022 ([link removed]) in the September 30 issue of MMWR ([link removed]) . A portion of the summary appears below.
In a large cohort of nursing home residents, receipt of a second mRNA COVID-19 booster dose during circulation of SARS-CoV-2 Omicron subvariants was 74% effective at 60 days against severe COVID-19–related outcomes (including hospitalization or death) and 90% against death alone compared with receipt of a single booster dose. . . .
Efforts should be made to ensure that nursing home residents remain up to date with recommended booster doses of COVID-19 vaccines.
Access the MMWR article in HTML ([link removed]) or PDF ([link removed]) .
Related Link
* MMWR ([link removed]) main page provides access to MMWR Weekly and its companion publications
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Upcoming Events
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Virtual: National Foundation for Infectious Diseases hosts "Clinical Vaccinology Course" on November 16–18; CME/CNE available
The National Foundation of Infectious Diseases ([link removed]) (NFID) Clinical Vaccinology Course ([link removed]) will be held online November 16–18. This 3-day online course focuses on new developments and issues related to use of vaccines. Expert faculty provide the latest information on vaccines, including updated recommendations for vaccinations across the lifespan, and innovative and practical strategies for ensuring timely and appropriate vaccination.
Continuing medical education (CME) and continuing nursing education (CNE) ([link removed]) credit will be offered.
Register for the online course ([link removed]) ($750 fee).
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On-demand: CDC’s “The Pink Book” chapter webinars on vaccine-preventable diseases and best practices roll out weekly. HPV webinar now available, with CE.
CDC continues its free 19-part pre-recorded webinar series ([link removed]) to provide a chapter-by-chapter overview of the 14th edition of Epidemiology and Prevention of Vaccine-Preventable Diseases ([link removed]) (also known as "The Pink Book").
The webinar on human papillomavirus (HPV) was released on October 4. Fourteen webinars are now available on demand. Additional webinars will be released weekly, concluding on November 1, 2022.
No registration is required to view the sessions. Information and program details are available on CDC's Pink Book Webinars ([link removed]) series web page.
CME, CNE, CPE, and CEU credits are available for each event. Questions about the material can be submitted to [email protected].
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For more upcoming events, visit our Calendar of Events ([link removed]).
Editorial Information
Editor-in-Chief
Kelly L. Moore, MD, MPH
Managing Editor
John D. Grabenstein, RPh, PhD
Associate Editor
Sharon G. Humiston, MD, MPH
Writer/Publication Coordinator
Taryn Chapman, MS
Courtnay Londo, MA
Style and Copy Editor
Marian Deegan, JD
Web Edition Managers
Arkady Shakhnovich
Jermaine Royes
Contributing Writer
Laurel H. Wood, MPA
Technical Reviewer
Kayla Ohlde
About IZ Express
Immunize.org welcomes redistribution of this issue of IZ Express or selected articles. When you do so, please add a note that Immunize.org is the source of the material and provide a link to this issue ([link removed]).
IZ Express is supported in part by Grant No. 1NH23IP922654 from the National Center for Immunization and Respiratory Diseases, CDC. Its contents are solely the responsibility of Immunize.org and do not necessarily represent the official views of CDC.
IZ Express Disclaimer ([link removed])
ISSN: 2771-8085
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