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Issue 1,647: August 17, 2022

Top Stories
* Immunize​.org updates its “Ask the Experts: COVID-19” content, incorporating vaccination of children under age 5 and Novavax vaccine for adults

* CDC expands its interim clinical considerations for monkeypox vaccination, including guidance for a new intradermal administration option for Jynneos

* Immunize​.org updates new “Vaccines: Monkeypox” main page with the latest CDC and FDA resources on Jynneos and the alternative intradermal dosing regimen

* American College Health Association releases two new toolkits to encourage vaccination of college students and build vaccine confidence on campus

* Back-to-school season is here! Spotlight: Immunize​.org resources focused on adolescent vaccination.

* August is National Immunization Awareness Month; continue to promote resources using #ivax2protect

* Vaccines in the news

Featured Resources
* What you measure gets better! Vaccine Track gives users access to near real-time data on uptake of CDC-recommended adult vaccines.

* Boost Oregon announces a TikTok challenge to improve young people’s COVID-19 vaccination rates; upload submissions by August 26

* Organizing a new vaccination program? Use Immunize​.org’s Vaccinating Adults: A Step-by-Step Guide—free to download by chapter or in its entirety.

Notable Publications
* “Association of COVID-19 Vaccination during Pregnancy with Incidence of SARS-CoV-2 Infection in Infants” published in JAMA Internal Medicine

* “COVID-19 Vaccination Intentions, Concerns, and Facilitators among U.S. Parents of Children Ages 6 Months through 4 Years” published in JAMA Network Open

Upcoming Events
* Virtual: CHOP's Current Issues in Vaccines webinar on September 14 features Dr. Paul Offit discussing COVID-19 boosters, yearly vaccines, and variant-specific vaccines; CE available

* On-demand: CDC’s recorded chapter-by-chapter webinars on vaccine-preventable diseases and best practices from “The Pink Book” roll out weekly; CE available

Editorial Information
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Top Stories
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Immunize​.org updates its “Ask the Experts: COVID-19” content, incorporating vaccination of children under age 5 and Novavax vaccine for adults

Immunize​.org published an updated version of its popular Ask the Experts: COVID-19 ([link removed]) web page on August 3. This extensive list of clinical questions and answers addresses COVID-19 recommendations and clinical considerations, including vaccine recommendations for children age 6 months through 4 years, and information about Novavax COVID-19 Vaccine.

Immunize​.org’s Ask the Experts ([link removed]) main page leads you to 30 distinct web pages on a variety of topics with more than 1,200 common or challenging questions and answers about vaccines and their administration. Immunize​.org’s team of experts includes Kelly L. Moore, MD, MPH (team lead), Carolyn B. Bridges, MD, FACP, and Iyabode Beysolow, MD, MPH.

Look for a Special Edition of IZ Express – Ask the Experts on Thursday, August 18, featuring questions and answers on Hib vaccination and COVID-19 vaccines.

Related Links
* Immunize​.org: Ask the Experts: COVID-19 ([link removed]) web page
* Immunize​.org: Ask the Experts ([link removed]) main page to access more than 1,200 questions and answers

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CDC expands its interim clinical considerations for monkeypox vaccination, including guidance for a new intradermal administration option for Jynneos

CDC updated their Monkeypox: Vaccine Considerations web page with interim clinical considerations for use of Jynneos and ACAM2000 vaccines during the 2022 U.S. monkeypox outbreak ([link removed]) on August 15. This important guidance on use of monkeypox vaccines includes the new intradermal (ID) administration option for Jynneos. ID administration requires only 0.1 mL of vaccine, expanding the number of people who can be vaccinated (the standard subcutaneous dose is 0.5 mL); however, improper administration, delivering the vaccine too deeply beneath the intradermal layer, results in an ineffective dose. Training in ID injection technique is essential to properly deliver an effective immunizing dose.

Immunize​.org’s Vaccines: Monkeypox ([link removed]) main page provides links to new CDC and FDA resources related to both standard (subcutaneous) and alternative (ID) dosing regimens. Healthcare professionals administering or counseling patients on monkeypox vaccination should review these changes.

Related Links
* CDC: Monkeypox: Vaccine Considerations ([link removed])
* CDC: Video: How to Administer a Jynneos Vaccine Intradermally ([link removed])
* CDC: Monkeypox ([link removed]) main page
* FDA: Fact Sheet for Healthcare Providers Administering Vaccine: Emergency Use Authorization of Jynneos (Smallpox and Monkeypox Vaccine, Live, Non-replicating) for Prevention of Monkeypox Disease in Individuals Determined to Be at High Risk for Monkeypox Infection ([link removed])
* FDA: Fact Sheet for Recipients and Caregivers about Jynneos (Smallpox and Monkeypox Vaccine, Live, Non-replicating) to Prevent Monkeypox Disease in Individuals Determined to Be at High Risk for Monkeypox Infection ([link removed])
* Immunize​.org: Vaccines: Monkeypox ([link removed]) main page

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Immunize​.org updates new “Vaccines: Monkeypox” main page with the latest CDC and FDA resources on Jynneos and the alternative intradermal dosing regimen

Immunize​.org updated its new Vaccines: Monkeypox ([link removed]) main page that provides links to key resource pages from CDC, FDA, Immunize​.org, and other professional organizations. The page has been revised to incorporate new resources from CDC and FDA related to the standard (subcutaneous) and alternative (intradermal) dosing regimens for the live, non-replicating vaccine against monkeypox, Jynneos (Bavarian Nordic).

Bookmark Immunize​.org’s new Vaccines: Monkeypox ([link removed]) main page for key links to important resources. The page will be updated as new guidelines and resources become available.

Related Links
* CDC: Monkeypox ([link removed]) main page
* CDC: Monkeypox: Vaccine Considerations ([link removed]) web page
* CDC: Video: How to Administer a Jynneos Vaccine Intradermally ([link removed])
* CDC: Jynneos Smallpox and Monkeypox Vaccine: Standing Orders for Administering Vaccine ([link removed]) (PDF)
* CDC: Jynneos Smallpox and Monkeypox Vaccine: Storage and Handling Summary ([link removed]) (PDF)
* Immunize​.org: Vaccines: Monkeypox ([link removed]) main page

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American College Health Association releases two new toolkits to encourage vaccination of college students and build vaccine confidence on campus

The American College Health Association (ACHA) released two toolkits for colleges and universities for the 2022–2023 academic year. The CoVAC Student Ambassador Toolkit ([link removed]) provides a framework for peer education and the Vaxforward toolkit ([link removed]) focuses on building vaccine confidence.

Student ambassadors can be a powerful force for behavior change on campus. The CoVAC Student Ambassador Toolkit ([link removed]) can help you create a student ambassador program to stop the spread of COVID-19 on your campus. Updated and expanded resources include:
* Student Ambassador Program Planning Guide
* Event Planning Guide
* Communication Plan
* Workshop Lesson Plan
* Easy-to-Share Graphics

ACHA’s Vaxforward toolkit ([link removed]) includes key facts about COVID-19 vaccines and boosters in easy-to-read language—plus communication tips, sample messages, and credible resources to share.

Related Links
* ACHA: Campus COVID-19 Vaccination and Mitigation Initiative (CoVAC) ([link removed]) main page
* ACHA: CoVAC Student Ambassador Toolkit ([link removed])
* ACHA: Vaxforward toolkit ([link removed])

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Back-to-school season is here! Spotlight: Immunize​.org resources focused on adolescent vaccination.

Immunize​.org offers many useful materials on adolescent vaccination for professionals and parents.

Resources for Adolescent Vaccination ([link removed]) main page offers all the adolescent educational materials from Immunize​.org and partner organizations.

Adolescent Vaccination ([link removed]) main page contains the handouts that pertain to adolescent vaccinations.

CDC Schedules ([link removed]) main page provides print-ready PDFs of the recommended vaccination schedules for children and adolescents, as well as for adults.

Screening Checklists about Vaccine Contraindications and Precautions ([link removed]) main page links you to forms that patients can fill out to expedite assessment of vaccination needs and contraindications.

Give2MenACWY ([link removed]) website offers resources to help providers increase teen vaccination and MenACWY booster dose rates.

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August is National Immunization Awareness Month; continue to promote resources using #ivax2protect

August is National Immunization Awareness Month ([link removed]) (NIAM). This annual observance highlights efforts to protect people of all ages against vaccine-preventable diseases through on-time vaccination. This year, NIAM focuses our attention on the urgent need to catch up on routine visits and vaccinations that were disrupted by the COVID-19 pandemic.

CDC’s NIAM web page includes key messages, sample social media content, and educational resources in two toolkits:
* One for reaching healthcare professionals ([link removed])
* Another for reaching parents and patients ([link removed])

CDC encourages its partners to share these messages and resources throughout August using the hashtag #ivax2protect. Stay tuned for more resources to be released throughout the coming weeks.

Related Links
* CDC: NIAM ([link removed]) web page
* CDC: Toolkit for Reaching Healthcare Professionals ([link removed]) main page
* CDC: Toolkit for Reaching Parents and Patients ([link removed]) main page

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Vaccines in the news

These recent articles convey the potential risks of vaccine-preventable diseases and the importance of vaccination.

* Washington Post: Polio Virus Is Found in New York City Wastewater ([link removed]) (8/12/22)

* CNN: Around 1 Million Children in London Offered Polio Boosters after Virus Is Detected in Sewage ([link removed]) (8/10/22)

* FDA: Monkeypox Update: FDA Authorizes Emergency Use of Jynneos Vaccine to Increase Vaccine Supply ([link removed]) (8/9/22)

* ABC: CDC Sends Team to New York to Investigate Polio Case ([link removed]) (8/8/22)

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Featured Resources
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What you measure gets better! Vaccine Track gives users access to near real-time data on uptake of CDC-recommended adult vaccines.

Vaccine Track ([link removed]) is a new website that displays state and national trend data on use of vaccines recommended for U.S. adults. Vaccine Track is produced through a partnership between GSK and Iqvia, a data analytics company.

As an example of its usefulness, the Vaccine Track main page shows how adult vaccination rates fell during the COVID-19 pandemic, using claims data from Medicare, Medicaid, commercial, and cash services. Vaccine Track shows vaccination trends to help inform and achieve clinical and public health efforts to reach Healthy People 2030 immunization objectives ([link removed].). The data will be refreshed quarterly with only a 3-month lag time. CDC adult vaccination coverage reports are typically updated once every 12 months with data at least 1 year old at the time of publication. Vaccine Track is the first tool to make comprehensive vaccination claims data across different payer types available publicly.

Users can explore state and national vaccination trends for adults age 19 years and older in the United States:
* Across multiple vaccines
* Across years
* By demographics (e.g., age, race/ethnicity, gender, payer type)

Related Links
* GSK: Vaccine Track ([link removed]) web page
* GSK media release: GSK and IQVIA Launch Vaccine Track, a Data Trend Platform to Help Improve Adult Vaccination in Communities Nationwide ([link removed]) (8/8/22)

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Boost Oregon announces a TikTok challenge to improve young people’s COVID-19 vaccination rates; upload submissions by August 26

In the United States, COVID-19 vaccination rates among young people are lower than in other age groups. To get the word out about why youth COVID-19 vaccination is so important, Boost Oregon created a TikTok challenge. Invite your social media friends to produce a song, dance, skit, animation, or another creative message. Then record it as a video that runs 60 seconds or less and caption it with #vaxinaction.

Upload your video(s) to the web page available at boostoregon.org/fyi ([link removed]) by 12 p.m. (PT) on August 26. The winner will be announced by September 2 and will receive a Nintendo Switch gaming system.

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Organizing a new vaccination program? Use Immunize​.org’s Vaccinating Adults: A Step-by-Step Guide—free to download by chapter or in its entirety.

Download Immunize​.org’s free 142-page book on adult vaccination to help build your program and train your team: Vaccinating Adults: A Step-by-Step Guide (Guide) ([link removed]).

This thorough "how to" guide on adult vaccination provides easy-to-use, practical information covering all essential activities. It helps vaccine providers enhance their existing adult vaccination services or introduce them into any clinical setting.

The Guide is available to download/print either by chapter or in its entirety free at www.immunize.org/guide ([link removed]). The National Vaccine Program Office and CDC both supported the development of the Guide and provided early technical review.

The Guide is a valuable resource to assist providers in increasing adult vaccination rates. Be sure to get a copy today!

Please note: this guide was produced in 2017, before the COVID-19 era, and reflects the recommendations of that time.

Related Links
* Vaccinating Adults: A Step-by-Step Guide ([link removed]) main page, permitting download of entire Guide (142 pages, PDF) ([link removed])
* View the table of contents and individual chapters (PDF):
+ Table of Contents ([link removed])
+ Step 1: Getting Started ([link removed])
+ Step 2: Setting Up for Vaccination Services ([link removed])
+ Step 3: Vaccine Storage and Handling ([link removed])
+ Step 4: Deciding Whom to Vaccinate ([link removed])
+ Step 5: Administering Vaccines ([link removed])
+ Step 6: Documentation and Related Issues ([link removed])
+ Step 7A: Financial Considerations ([link removed])
+ Step 7B: How to Bill for Adult Immunizations ([link removed])
* Immunize​.org’s educational materials (handouts) on adult immunization ([link removed])

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Notable Publications
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“Association of COVID-19 Vaccination during Pregnancy with Incidence of SARS-CoV-2 Infection in Infants” published in JAMA Internal Medicine

In the June 1 issue, JAMA Internal Medicine published Association of COVID-19 Vaccination during Pregnancy with Incidence of SARS-CoV-2 Infection in Infants ([link removed]). The Conclusions and Relevance section appears below.

The results of this Norwegian population-based cohort study suggested a lower risk of a positive test for SARS-CoV-2 during the first 4 months of life among infants born to mothers who were vaccinated during pregnancy. Maternal COVID-19 vaccination may provide passive protection to young infants, for whom COVID-19 vaccines are currently not available.

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“COVID-19 Vaccination Intentions, Concerns, and Facilitators among U.S. Parents of Children Ages 6 Months through 4 Years” published in JAMA Network Open

In the August 3 issue, JAMA Network Open published COVID-19 Vaccination Intentions, Concerns, and Facilitators among U.S. Parents of Children Ages 6 Months through 4 Years ([link removed]). The Conclusions and Relevance section appears below.

These results suggest that only a minority of parents of children in this age group are eager to vaccinate their children within the first few months of eligibility, with widespread concerns about COVID-19 vaccination for this age group. Thus, considerable efforts to increase parental COVID-19 vaccine confidence for children age 6 months through 4 years may be needed to maximize COVID-19 vaccination for this age group in the United States.

Table 1 ([link removed]) shows that among respondent parents, the most commonly selected COVID-19 vaccination concern for their children age 6 months through 4 years was possible long-term side effects. The most commonly selected facilitators for COVID-19 vaccination were more information showing COVID-19 vaccines are safe in children and more information showing COVID-19 vaccines are effective in children.

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Upcoming Events
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Virtual: CHOP's Current Issues in Vaccines webinar on September 14 features Dr. Paul Offit discussing COVID-19 boosters, yearly vaccines, and variant-specific vaccines; CE available

The Vaccine Education Center (VEC) at Children's Hospital of Philadelphia (CHOP) will present a 1-hour webinar on COVID-19 boosters, yearly vaccines, and what's next with variant-specific vaccines, beginning at 12:00 p.m. (ET) on September 14. Part of its Current Issues in Vaccines ([link removed]) series, the webinar will feature Paul Offit, MD, director of the VEC.

Free continuing-education credits (CME, CNE, and CPE) will be available for both the live and archived events.

Register for the webinar ([link removed]).

Related Link
* VEC's Vaccine Webinar Archive ([link removed]) web page

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On-demand: CDC’s recorded chapter-by-chapter webinars on vaccine-preventable diseases and best practices from “The Pink Book” roll out weekly; CE available

CDC continues its 19-part pre-recorded webinar series ([link removed]) to provide a chapter-by-chapter overview of the 14th edition of Epidemiology and Prevention of Vaccine-Preventable Diseases ([link removed]) (also known as "The Pink Book").

Webinar #8, on rotavirus and hepatitis A vaccines, was released on August 16. Additional webinars will be released weekly, concluding on November 1, 2022.

No registration is required to view the sessions. Information and program details are available on CDC's Pink Book Webinars series ([link removed]) web page.

CME, CNE, CPE, and CEU credits are available for each event. Questions about the material can be submitted to [email protected].

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For more upcoming events, visit our Calendar of Events ([link removed]).

Editorial Information
Editor-in-Chief
Kelly L. Moore, MD, MPH

Managing Editor
John D. Grabenstein, RPh, PhD

Associate Editor
Sharon G. Humiston, MD, MPH

Writer/Publication Coordinator
Taryn Chapman, MS
Courtnay Londo, MA

Style and Copy Editor
Marian Deegan, JD

Web Edition Managers
Arkady Shakhnovich
Jermaine Royes

Contributing Writer
Laurel H. Wood, MPA

Technical Reviewer
Robin VanOss

About IZ Express
Immunize​.org welcomes redistribution of this issue of IZ Express or selected articles. When you do so, please add a note that Immunize​.org is the source of the material and provide a link to this issue ([link removed]).

IZ Express is supported in part by Grant No. 1NH23IP922654 from the National Center for Immunization and Respiratory Diseases, CDC. Its contents are solely the responsibility of Immunize​.org and do not necessarily represent the official views of CDC.

IZ Express Disclaimer ([link removed])
ISSN: 2771-8085

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