Spotlight on NTM
Because of the difficulty in treating M. abscessus and other nontuberculous mycobacteria (NTM) infections, we have dedicated resources to fight these problematic bacteria. We are funding five active industry programs in NTM: two in the drug discovery phase, two in preclinical development (testing in preparation for clinical trials), and one in clinical trials.
These programs include the Beyond Air program, which is in the clinical trial phase and involves a non-traditional way of fighting NTM infections with the use of nitric oxide. Interim data from a Phase 2 pilot study showed that the potential treatment was well tolerated. The company expects full safety and efficacy results later this year.
The Foundation also has funded several academic research studies that seek to standardize NTM detection and treatment, examine novel biomarkers, and look at various treatment regimens.