From Immunize.org <[email protected]>
Subject IZ Express #1,630: CDC updates clinical considerations for COVID-19 vaccines, and more
Date May 4, 2022 10:00 AM
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Issue 1,630: May 4, 2022
Top Stories
* CDC updates clinical considerations for COVID-19 vaccines, including guidance on second booster doses and vaccination after SARS-CoV-2 infection
* Immunize​.org’s Hepatitis B Birth Dose Honor Roll recognizes 558 institutions, including 12 new honorees. Five previously honored institutions qualify for sustained honors.
* Influenza activity continues to increase in some areas and CDC reports a human case of avian influenza A(H5) in Colorado
* Spotlight: Review of Immunize​.org resources focused on enhancing clinic and practice operations
* Vaccines in the news


Immunize​.org Pages and Handouts
* Immunize​.org updates “Should You Be Vaccinated against Hepatitis B?”
* Immunize​.org updates “When Do Children and Teens Need Vaccinations?”
* Reminder: “Ask the Experts: Diphtheria, Tetanus, Pertussis” web page updated with recent pertussis trends and evidence on effectiveness of Tdap during pregnancy
* Immunize​.org updates its "Vaccine Timeline" main page


Featured Resources
* Explore the updated www.Give2MenACWY.org website to increase coverage for the MenACWY booster and other adolescent vaccinations


Notable Publications
* "Impact of Population Mixing between Vaccinated and Unvaccinated Subpopulations on Infectious Disease Dynamics: Implications for SARS-CoV-2 Transmission" published in Canadian Medical Association Journal
* MMWR Recap: Articles regarding mortality data and COVID-19 age-adjusted death rates by race and ethnicity


Global News
* “Public Health Actions to Control Measles among Afghan Evacuees during Operation Allies Welcome—United States, September–November 2021” published in MMWR
* “Response to Measles among Persons Evacuated from Afghanistan—Joint Base McGuire-Dix-Lakehurst, New Jersey, August–October 2021” published in MMWR


Upcoming Events
* Virtual: NFID hosts "COVID-19 Updates: Booster Doses" webinar on May 5
* Virtual: Hep Free Hawaii and other partners host "Hep Free Talk Story #2: Hepatitis B Vaccine Updates" webinar on May 18


Editorial Information
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Top Stories
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CDC updates clinical considerations for COVID-19 vaccines, including guidance on second booster doses and vaccination after SARS-CoV-2 infection

CDC updated their Interim Clinical Considerations addressing use of COVID-19 vaccines currently approved or authorized in the United States ([link removed]) on April 21. This guidance provides important details on use of COVID-19 vaccines. All healthcare professionals administering or counseling patients on COVID-19 vaccination should review all changes on the web page.

CDC summarized the April 21 changes as follows:
* Added considerations for the option to receive a second COVID-19 vaccine booster dose
* Updated guidance for COVID-19 vaccination after SARS-CoV-2 infection

View the CDC’s Interim Clinical Considerations web page addressing use of COVID-19 vaccines currently approved or authorized in the United States ([link removed]) .

Immunize​.org is in the process of updating its Vaccines: COVID-19 ([link removed]) page, its Ask the Experts: COVID-19 ([link removed]) page, and its Checklist of Current Versions of U.S. COVID-19 Vaccination Guidance and Clinic Support Tools to reflect the latest changes. Updates will be announced in IZ Express.

Related Links
* CDC: Interim COVID-19 Immunization Schedule for Ages 5 Years and Older ([link removed]) (PDF)
* CDC: COVID-19 Vaccine Administration Errors and Deviations ([link removed]) (PDF)
* Immunize​.org: Vaccines: COVID-19 ([link removed]) main page
* Immunize​.org: Ask the Experts: COVID-19 ([link removed]) web page


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Immunize​.org’s Hepatitis B Birth Dose Honor Roll recognizes 558 institutions, including 12 new honorees. Five previously honored institutions qualify for sustained honors.

Immunize​.org is pleased to announce acceptance of twelve new institutions into its Hepatitis B Birth Dose Honor Roll ([link removed]) , for a total of 558 honorees. The birthing institutions are listed below with their reported hepatitis B birth dose coverage rates in parentheses.
* Erlanger East Hospital, Chattanooga, TN (95%)
* Evans Army Community Hospital, Colorado Springs, CO (90%)
* Sanford Aberdeen Medical Center, Aberdeen, SD (90%)
* Sanford Bemidji Medical Center, Bemidji, MN (97%)
* Sanford Luverne Medical Center, Luverne, MN (90%)
* Sanford Medical Center, Bismarck, ND (97%)
* Sanford Medical Center Fargo, Fargo, ND (98%)
* Sanford Sheldon Medical Center, Sheldon, IA (95%)
* Sanford Thief River Falls Medical Center, Thief River Falls, MN (95%)
* Sanford USD Medical Center and Hospital, Sioux Falls, SD (97%)
* Sanford Vermillion Medical Center, Vermillion, SD (97%)
* Sanford Worthington Medical Center, Worthington, MN (93%)

Several institutions are being recognized for qualifying for an additional year:
* Community Hospital, Grand Junction, CO (90%) (2 years)
* Denver Health Medical Center, Denver, CO (93%) (6 years)
* Sabetha Community Hospital, Sabetha, KS (96%) (6 years)
* Joint Base Elmendorf-Richardson Hospital, Anchorage, AK (94%) (7 years)
* Arkansas Valley Regional Medical Center, La Junta, CO (97%) (8 years)

The Honor Roll now includes 558 birthing institutions from 44 states, the District of Columbia, Puerto Rico, Guam, Saipan, and a U.S. military base in England.

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The Honor Roll is a key part of Immunize​.org’s initiative urging the nation’s hospitals to Give Birth to the End of Hep B ([link removed]) . Hospitals and birthing centers are recognized for attaining high coverage for hepatitis B vaccine at birth and meeting additional criteria. Immunize​.org urges qualifying healthcare organizations to apply for the Hepatitis B Birth Dose Honor Roll online ([link removed]) .

To qualify for the Hepatitis B Birth Dose Honor Roll, a birthing institution must have: (1) reported a coverage rate of 90% or greater, over a 12-month period, for administering hepatitis B vaccine before hospital discharge to all newborns, including those whose parents refuse vaccination, and (2) implemented specific written policies, procedures, and protocols to protect all newborns from hepatitis B virus infection before hospital discharge.

Honorees are awarded an 8.5" x 11" color certificate suitable for framing and their acceptance is announced to IZ Express’s 53,000+ readers.

Please visit the Hepatitis B Birth Dose Honor Roll web page that lists these institutions and celebrates their exceptional efforts to protect infants from perinatal hepatitis B transmission.

Related Immunize​.org Resources
* Give Birth to the End of Hep B ([link removed]) main page
* Fact sheet about honor roll: Do You Qualify for the Hepatitis B Birth Dose Honor Roll? If So, Apply Today. ([link removed])
* Handout on Immunize​.org’s campaign: Give Birth to the End of Hep B ([link removed])
* Hepatitis B Birth Dose Honor Roll ([link removed]) web page


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Influenza activity continues to increase in some areas and CDC reports a human case of avian influenza A(H5) in Colorado

Influenza Surveillance
For week 16, ending on April 23, CDC's Weekly U.S. Influenza Surveillance Report, FluView ([link removed]) summary reports that seasonal influenza activity continues to increase in some areas of the country. The high levels of acute respiratory illness reflected in the national map include both influenza and non-influenza (e.g., COVID-19) respiratory illnesses.

In other influenza news, a human case of avian influenza A(H5) was reported by Colorado this week ([link removed]) . The person had been in direct contact with infected poultry, developed mild symptoms of fatigue for a few days, and has fully recovered. This one H5-positive human case does not change the human health risk assessment associated with the current outbreak of avian H5N1 influenza currently reported among birds in 29 states.

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Influenza Vaccination Dashboard
CDC's new Weekly Flu Vaccination Dashboard ([link removed]) shares preliminary vaccination data. This week’s key fact: as of April 9, 2022, flu vaccination coverage for children age 6 months to 17 years among states and DC ranges from 32.9% to 79.7%; national coverage is 55.3%. Coverage for most jurisdictions this season as of April 9, 2022, is similar to the same time last season; coverage for most jurisdictions this season is lower compared with pre-pandemic coverage at the same time during the 2019–20 flu season.

CDC recommends everyone age 6 months and older get an annual influenza vaccine. Influenza and COVID-19 vaccines may be given at the same visit, if needed. COVID-19 vaccination alone provides no protection from influenza or any other respiratory virus.

Vaccine Finder
If you don’t provide influenza vaccine at your site, please strongly recommend vaccination and refer people to sites that do vaccinate. Use VaccineFinder, a user-friendly website to help people of all ages find influenza, COVID-19, and other vaccines ([link removed]) . Participating providers can update their vaccine inventory estimates on VaccineFinder. For questions or more information, contact [email protected] (mailto:[email protected]) .

Related Links
* CDC: Weekly Flu Vaccination Dashboard ([link removed]) main page
* CDC: FluView ([link removed]) main page
* CDC: Influenza (Flu) ([link removed]) main page
* CDC: U.S. Case of Human Avian Influenza A(H5) Virus Reported ([link removed] )
* CDC: Bird Flu Current Situation Summary ([link removed] )
* Immunize​.org: Free educational materials and patient handouts related to influenza ([link removed])
* Immunize​.org: Vaccines: Influenza ([link removed]) main page
* Immunize​.org: Ask the Experts: Influenza ([link removed]) main page
* VaccineFinder ([link removed]) website
* Families Fighting Flu: Flu Resources for Healthcare Professionals ([link removed]) main page

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Spotlight: Review of Immunize​.org resources focused on enhancing clinic and practice operations

In this week's Spotlight, we summarize Immunize​.org resources that focus on enhancing clinic and practice operations.

Our topic index on our Clinic Tools ([link removed]) main page is a one-stop source of practical information for vaccine providers. You will find "how-to" information about vaccinating in any setting.

Our C ([link removed]) linic Tools: Storage and Handling ([link removed]) main page offers printable temperature logs to monitor freezers and refrigerators. This site also includes a troubleshooting record to document the occurrence and resolution of questionable or unacceptable vaccine storage events.

Our Clinic Tools: Documenting Vaccination ([link removed]) main page offers forms to document vaccination or declination of vaccination, as well as various forms and checklists useful to healthcare personnel.

Our free downloadable book, Vaccinating Adults: A Step-by-Step Guide ([link removed]) , is a "how to" guide that provides easy-to-use, practical information covering essential adult immunization activities.

Our Key Vaccination Resources for Healthcare Professionals ([link removed]) is a 5-page annotated list of resources for people who vaccinate or oversee vaccination clinics. The document lists foundational content with which every vaccinator should be familiar, supplemental content useful after completing foundational training, and additional tools to help providers grow in vaccination expertise.

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Vaccines in the news

These recent articles convey the potential risks of vaccine-preventable diseases and the importance of vaccination.
* ABC News: Measles Outbreaks Possible amid ‘Perfect Storm’ of Conditions, WHO and UNICEF Warn ([link removed]) (4/27/22)
* Washington Post: Moderna Seeks Authorization of Coronavirus Vaccine for Youngest Children ([link removed]) (4/28/22)
* CNN: Pfizer Requests FDA Authorization for COVID-19 Booster for Kids 5 through 11 ([link removed] ) (4/26/22)
* New York Times: Do Vaccines Protect against Long COVID? ([link removed]) (4/26/22)
* WHO: World Immunization Week 2022 ([link removed] ) (4/24/22)
* News Medical Life Sciences: World Immunization Week 2022: Striving for a Long Life for All with the International Vaccine Institute ([link removed] ) (4/25/22)

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Immunize​.org Pages and Handouts
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Immunize​.org updates “Should You Be Vaccinated against Hepatitis B?”

Immunize​.org updated its Should You Be Vaccinated against Hepatitis B? ([link removed]) handout for adults. Changes were made to incorporate the newest ACIP recommendations for routine hepatitis B vaccination of all adults through age 59 years, in addition to children and older adults at increased risk.

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Related Links
* Immunize​.org: Handouts ([link removed]) main page to see educational materials sorted by category
* Immunize​.org: Clinic Tools ([link removed]) main page and its nine subtopics
* Immunize​.org: Ask the Experts: Hepatitis B ([link removed]) web page
* Immunize​.org: Educational Materials for Patients and Staff ([link removed]) —an alphabetical list of more than 230 ready-to-print staff educational materials and patient handouts


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Immunize​.org updates “When Do Children and Teens Need Vaccinations?”

Immunize​.org updated its 1-page patient handout titled When Do Children and Teens Need Vaccinations? ([link removed]) It now includes COVID-19 vaccine, dengue vaccine (for certain children, as indicated in the footnote), and a new footnote that reminds that HPV vaccine may be started at age 9 years.

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Related Links
* Immunize​.org: Handouts ([link removed]) main page to see educational materials sorted by category
* Immunize​.org: Clinic Tools ([link removed]) main page and its nine subtopics
* Immunize​.org: Educational Materials for Patients and Staff ([link removed]) —an alphabetical list of more than 230 ready-to-print staff educational materials and patient handouts


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Reminder: “Ask the Experts: Diphtheria, Tetanus, Pertussis” web page updated with recent pertussis trends and evidence on effectiveness of Tdap during pregnancy

Immunize​.org updated its popular Ask the Experts: Diphtheria, Tetanus, Pertussis ([link removed]) web page on March 31. Updates include the following:
* Recent epidemiological trends of pertussis
* Evidence that Tdap vaccination during pregnancy is highly effective at protecting newborns from pertussis illness or hospitalization
* When considering post-exposure chemoprophylaxis or symptom monitoring, healthcare personnel vaccinated with Tdap who are at high risk themselves or likely to expose patients at high risk of pertussis complications should be managed like those who have not had Tdap

Note: The original article announcing these Ask the Expert ([link removed]) stated in error that the practice of cocooning (Tdap vaccination of previously unvaccinated close contacts of newborns) is not recommended. In fact, cocooning alone may not be effective and is difficult to implement; however, it remains recommended in combination with Tdap vaccination of the mother during pregnancy and on-time DTaP vaccination of the infant.

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Immunize​.org's Ask the Experts ([link removed]) main page leads you to 30 distinct web pages on a variety of topics with more than 1,100 common or challenging questions and answers about vaccines and their administration. Immunize​.org's team of experts includes Kelly L. Moore, MD, MPH (team lead), Carolyn B. Bridges, MD, FACP, and Iyabode Beysolow, MD, MPH.

Related Links
* Immunize​.org: Ask the Experts: Diphtheria, Tetanus, Pertussis ([link removed]) web page
* Immunize​.org: Standing Orders for Administering Diphtheria, Tetanus, Acellular Pertussis Vaccine (DTaP) to Children Younger Than Age 7 Years ([link removed])
* Immunize​.org: Standing Orders for Administering (Tetanus-Diphtheria Toxoids and Pertussis) Td/Tdap Vaccine to Adults ([link removed])
* Immunize​.org: Standing Orders for Administering (Tetanus-Diphtheria Toxoids and Pertussis) Tdap/Td Vaccine to Children Age 7 and Older ([link removed])
* Immunize​.org: Standing Orders for Administering (Tetanus-Diphtheria Toxoids and Pertussis) Tdap to Pregnant Women ([link removed])


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Immunize​.org updates its "Vaccine Timeline" main page

Immunize​.org's Vaccine Timeline ([link removed]) main page was updated on April 1 to include new events related to vaccines and immunization. The chart on the main page displays many of the vaccine- and immunization-related events that occurred since Edward Jenner's first smallpox vaccination in 1796.

If you would like to suggest an event to add, contact us at [email protected] (mailto:[email protected]) .

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Featured Resources
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Explore the updated www.Give2MenACWY​.org website to increase coverage for the MenACWY booster and other adolescent vaccinations

Immunize​.org's www.Give2MenACWY.org ([link removed]) website promotes the importance of adolescent vaccination, including administering the recommended MenACWY vaccine booster dose at age 16. Many teens are behind on vaccines because of the pandemic, so vaccination is more important than ever.

Materials on this colorful website for healthcare professionals incorporate the 2020 ACIP meningococcal vaccine recommendations ([link removed]) and coverage statistics from CDC’s National Immunization Survey–Teen (NIS–Teen). One particularly popular resource on the site is the updated Algorithm for MenACWY Immunization in Adolescents 11 through 18 Years of Age ([link removed]) .

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The website is divided into five easy-to-access sections:
* Vaccinate Teens ([link removed]) – Teen vaccination schedules and tips for improving vaccination rates
* Give 2 Doses ([link removed]) – Tools to help improve second dose coverage of MenACWY vaccine
* 16-Year-Old Visit ([link removed]) – Resources to help providers and patients remember the important vaccines recommended for 16-year-olds
* Tools for Providers ([link removed]) – Tools to explain meningococcal ACWY vaccine recommendations and improve coverage for all adolescent vaccines
* Resources ([link removed]) – Links to print materials ([link removed]) , organizations ([link removed]) involved in adolescent vaccination, personal stories ([link removed]) about the importance of vaccination, and other resources ([link removed]) of interest

The site also categorizes materials ([link removed]) according to whether they are primarily of interest to providers, to adolescents, or to parents.

Visit Give2MenACWY.org ([link removed]) and enjoy browsing (and deploying) its bountiful resources.

Related Links
* Give2MenACWY.org ([link removed]) website
* Algorithm for MenACWY Immunization in Adolescents 11 through 18 Years of Age ([link removed])
* MenACWY: You're Not Done If You Give Just One: Give 2 Doses to Strengthen Protection ([link removed])
* Recommending MenACWY: What to Say and How to Say It ([link removed])
* Top 10 Ways to Improve Adolescent Immunization Rates ([link removed])
* Developing an Immunization Culture in Your Office ([link removed])
* Know Your Rates: Measuring Immunization Success in Your Practice ([link removed])
* You're 16: We Recommend These Vaccines for You ([link removed])
* 2020 ACIP meningococcal vaccine recommendations ([link removed])
* National, Regional, State, and Selected Local Area Vaccination Coverage among Adolescents Aged 13–17 Years — United States, 2020 ([link removed])
* Dear Colleague Letter: 16-Year-Old Patients: Make Sure They Receive Their Annual Well Visit and Vaccinations ([link removed]) – signed by six medical societies
* Ask the Experts: Meningococcal ACWY ([link removed])


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Notable Publications
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"Impact of Population Mixing between Vaccinated and Unvaccinated Subpopulations on Infectious Disease Dynamics: Implications for SARS-CoV-2 Transmission" published in Canadian Medical Association Journal

In the April 25 issue, Canadian Medical Association Journal published Impact of Population Mixing between Vaccinated and Unvaccinated Subpopulations on Infectious Disease Dynamics: Implications for SARS-CoV-2 Transmission ([link removed]) . Portions of the abstract appear below.

We found that the risk of infection was markedly higher among unvaccinated people than among vaccinated people under all mixing assumptions. The contact-adjusted contribution of unvaccinated people to infection risk was disproportionate, with unvaccinated people contributing to infections among those who were vaccinated at a rate higher than would have been expected based on contact numbers alone.…

Although risk associated with avoiding vaccination during a virulent pandemic accrues chiefly to people who are unvaccinated, their choices affect risk of viral infection among those who are vaccinated in a manner that is disproportionate to the portion of unvaccinated people in the population.

Related Link
* Global News: Unvaccinated People Increase Risk of COVID-19 Infection among Vaccinated: Study ([link removed]) (4/25/22)


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MMWR Recap: Articles regarding mortality data and COVID-19 age-adjusted death rates by race and ethnicity

CDC recently published several articles first distributed as MMWR Early Releases:
* Provisional Mortality Data—United States, 2021 (MMWR, April 29, HTML ([link removed]) or PDF ([link removed]) )
* Provisional COVID-19 Age-Adjusted Death Rates, by Race and Ethnicity—United States, 2020–2021 (MMWR, April 29, HTML ([link removed]) or PDF ([link removed]) )

Related Link
* MMWR ([link removed]) main page provides access to MMWR Weekly and its companion publications

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Global News
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“Public Health Actions to Control Measles among Afghan Evacuees during Operation Allies Welcome—United States, September–November 2021” published in MMWR

CDC published Public Health Actions to Control Measles among Afghan Evacuees during Operation Allies Welcome—United States, September–November 2021 ([link removed]) in the April 29 issue of MMWR ([link removed]) . A portion of the media summary appears below.

This report describes the successful whole-of-government effort to contain measles among Afghan evacuees during Operation Allies Welcome through rapid mass vaccination campaigns. A coordinated response that included a 21-day quarantine and a pause in incoming flights led to high vaccination coverage among evacuees. Measles transmission among evacuees was very limited, and there were no measles cases among the staff or volunteers at the military bases or hotel used for isolation and quarantine, and importantly, no spread into the surrounding communities.

Related Link
* MMWR ([link removed]) main page provides access to MMWR Weekly and its companion publications


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“Response to Measles among Persons Evacuated from Afghanistan—Joint Base McGuire-Dix-Lakehurst, New Jersey, August–October 2021” published in MMWR

CDC published Notes from the Field: Response to Measles among Persons Evacuated from Afghanistan—Joint Base McGuire-Dix-Lakehurst, New Jersey, August–October 2021 ([link removed]) in the April 29 issue of MMWR ([link removed]) . A portion of the media summary appears below.

This report describes how the spread of measles among Afghan evacuees was successfully prevented during Operation Allies Welcome at Joint Base McGuire-Dix-Lakehurst (JBMDL). Several guests were exposed to a measles case during their inbound flight and a rapid mass vaccination campaign, quarantine, and flight pauses prevented further spread of infectious diseases.

Related Link
* MMWR's main page ([link removed]) provides access to MMWR Weekly and its companion publications

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Upcoming Events
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Virtual: NFID hosts "COVID-19 Updates: Booster Doses" webinar on May 5

The National Foundation for Infectious Diseases (NFID) will offer a webinar titled COVID-19 Updates: Booster Doses ([link removed]) on May 5 at 12:00 p.m. (ET). During this program, current recommendations for COVID-19 vaccines and booster doses will be discussed, along with strategies for healthcare professionals to effectively communicate COVID-19 vaccination recommendations. Speakers will also address audience-submitted questions.

There is no fee to participate in this activity, but registration is required ([link removed]) .

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Virtual: Hep Free Hawaii and other partners host "Hep Free Talk Story #2: Hepatitis B Vaccine Updates" webinar on May 18

Hep Free Hawaii is collaborating with the Hawaii Immunization Coalition, the Hawaii Comprehensive Cancer Coalition, the UH Cancer Center, and Dynavax Technologies to offer a webinar titled Hep Free Talk Story #2: Hepatitis B Vaccine Updates ([link removed]) on May 18 at 6:00 p.m. (ET). This webinar is part of a series on hepatitis B vaccine updates, including new universal adult recommendations, two-dose options, and co-administration opportunities with other vaccines. During this program, there will be a discussion on the new CDC recommendations on hepatitis B vaccines for all adults age 19 through 59.

Register today ([link removed]) .

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For more upcoming events, visit our Calendar of Events ([link removed]) .
Editorial Information
Editor-in-Chief
Kelly L. Moore, MD, MPH
Managing Editor
John D. Grabenstein, RPh, PhD
Associate Editor
Sharon G. Humiston, MD, MPH
Writer/Publication Coordinator
Taryn Chapman, MS
Courtnay Londo, MA
Style and Copy Editor
Marian Deegan, JD
Web Edition Managers
Arkady Shakhnovich
Jermaine Royes
Contributing Writer
Laurel H. Wood, MPA
Technical Reviewer
Robin VanOss

About IZ Express
Immunize​.org welcomes redistribution of this issue of IZ Express or selected articles.
When you do so, please add a note that Immunize​.org is the source of the material and provide a link to this issue ([link removed]) .

IZ Express is supported in part by Grant No. 1NH23IP922654 from the National Center for Immunization and Respiratory Diseases, CDC. Its contents are solely the responsibility of Immunize​.org and do not necessarily represent the official views of CDC.

IZ Express Disclaimer ([link removed])
ISSN: 2771-8085
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