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IZ Express #1,614 (formerly IAC Express): New ACIP pneumococcal recommendations, and more.
| From | Immunization Action Coalition <[email protected]> |
| Subject | IZ Express #1,614 (formerly IAC Express): New ACIP pneumococcal recommendations, and more. |
| Date | February 2, 2022 11:01 AM |
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Issue 1,614: February 2, 2022 Formerly IAC Express
Top Stories
* “Use of 15-Valent Pneumococcal Conjugate Vaccine and 20-Valent Pneumococcal Conjugate Vaccine among U.S. Adults: Updated Recommendations of the Advisory Committee on Immunization Practices—United States, 2022” published in MMWR
* Immunize.org introduces new, print-ready patient handout "Not Sure If You Can Get an Influenza Vaccine?"
* Are you using the most current COVID-19 vaccination schedules? Check these tables to be sure.
* “Effectiveness of a Third Dose of Pfizer-BioNTech and Moderna Vaccines in Preventing COVID-19 Hospitalization among Immunocompetent and Immunocompromised Adults—United States, August–December 2021” published in MMWR
* Influenza activity expected to continue for several more weeks; keep vaccinating
* February is National Cancer Prevention Month; arm your patients with HPV and hepatitis B vaccinations in the fight to prevent cancer
* IZ Express keeps readers up to date on what’s new in vaccines each week; invite your colleagues to subscribe!
* Spotlight: Check out staff training and in-service resources provided by Immunize.org
* Journalists interview Immunize.org experts
* Vaccines in the News
Immunize.org Pages and Handouts
* Recap: These updated Immunize.org educational materials and web pages for clinicians were released during December and January
Vaccine Information Statements
* Recap: These new VISs and VIS translations were released during December and January
Featured Resources
* Asian Liver Center launches new “Hep B Moms” website with resources to prevent mother-to-child hepatitis B transmission
* National Association of School Nurses journal publishes supplement with five articles on school-located vaccination clinics
* CHOP’s Vaccine Education Center presents new video series featuring Paul Offit, MD, answering common questions related to vaccines
* CHOP's Vaccine Education Center revises its COVID-19 Vaccines Q&A handout for the public
* Voices for Vaccines releases podcast with Patsy Stinchfield, NP, answering parents' questions on kids and COVID-19 vaccines
* Newly updated “65+ Flu Defense” website offers resources for healthcare professionals serving older adults
* FREE! Immunize.org offers "Me Vacuné Contra el COVID-19” and “I Got My COVID-19 Vaccine” buttons and stickers. Free shipping! Available in English and Spanish.
* FREE! Order Immunize.org’s popular red "Vacuna Contra LA GRIPE" buttons and stickers. Free shipping! Available in Spanish.
* Explore the updated www.Give2MenACWY.org website to increase coverage for the MenACWY booster and other adolescent vaccinations
Notable Publications
* “A Prospective Cohort Study of COVID-19 Vaccination, SARS-CoV-2 Infection, and Fertility” published in American Journal of Epidemiology
* "Homologous and Heterologous COVID-19 Booster Vaccinations" published in NEJM
* MMWR Recap: Articles regarding COVID-19 vaccine effectiveness against death and hospitalization
Upcoming Events
* February 10–11: National Vaccine Advisory Committee meeting; watch virtually
Editorial Information (#Editorial)
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Top Stories
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“Use of 15-Valent Pneumococcal Conjugate Vaccine and 20-Valent Pneumococcal Conjugate Vaccine among U.S. Adults: Updated Recommendations of the Advisory Committee on Immunization Practices—United States, 2022” published in MMWR
CDC published Use of 15-Valent Pneumococcal Conjugate Vaccine and 20-Valent Pneumococcal Conjugate Vaccine among U.S. Adults: Updated Recommendations of the Advisory Committee on Immunization Practices—United States, 2022 ([link removed]) on January 28 in MMWR. A summary appears below.
Pneumococcal vaccination helps prevent serious diseases, like pneumonia, meningitis, and bloodstream infections. Two pneumococcal conjugate vaccines, PCV15 and PCV20, were licensed in 2021. Now there are updated pneumococcal vaccine recommendations for adults 19 years or older. CDC recommends adults 65 years of age or older who have not previously received a pneumococcal conjugate vaccine or whose previous vaccination history is unknown should receive either PCV20 or PCV15. If PCV15 is used, this should be followed by a dose of pneumococcal polysaccharide vaccine (PPSV23). Adults ages 19 through 64 years with certain underlying medical conditions or other risk factors who have not previously received a pneumococcal conjugate vaccine or whose previous vaccination history is unknown should receive either PCV20 or PCV15. If PCV15 is used, this should be followed by a dose of PPSV23.
The new recommendations are summarized in Table 1 of the MMWR article ([link removed]) .
Access the MMWR article in HTML ([link removed]) or PDF ([link removed]) .
Related Link
* MMWR's main page ([link removed]) provides access to MMWR Weekly and its companion publications
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Immunize.org introduces new, print-ready patient handout "Not Sure If You Can Get an Influenza Vaccine?"
In recent years, contraindications and precautions for influenza vaccination have been updated, expanding our ability to protect more people from serious influenza illness. However, some people mistakenly believe that they should not get an influenza vaccination due to outdated or inaccurate understanding of the risks and benefits of vaccination. To address this, Immunize.org has introduced a new patient handout Not Sure If You Can Get an Influenza Vaccine? ([link removed]) This handout, ideally printed as a two-sided, single page, addresses a variety of concerns (e.g., egg allergy, history of Guillain-Barre syndrome, pregnancy, and a weakened immune system).
[link removed] [link removed]
Related Links
* Immunize.org: Handouts: Influenza ([link removed]) main page
* Immunize.org: Handouts ([link removed]) main page to see educational materials sorted by category
* Immunize.org: Ask the Experts: Influenza ([link removed]) main page
* Immunize.org: Educational Materials for Patients and Staff ([link removed]) —an alphabetical list of more than 230 ready-to-print staff educational materials and patient handouts
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Are you using the most current COVID-19 vaccination schedules? Check these tables to be sure.
It is a challenge to keep up with the frequent adjustments to COVID-19 vaccination schedules. Review these tables to be sure you are following the latest version (last updated by CDC on January 7) and that you are using the current Emergency Use Authorization (EUA) Fact Sheets for healthcare providers and vaccine recipients. Changes made since January 1 are noted in bold print. Moderna and Pfizer-BioNTech mRNA vaccines are preferred, except when mRNA vaccine is contraindicated or when the patient wants Janssen (Johnson & Johnson, J&J) vaccine after being informed of risks and benefits.
COVID-19 recommended schedule for the general population ([link removed]) (y = years, w = weeks, mo = months):
Age Range Product Primary Series Booster dose? *
5 through 11 y Pfizer-BioNTech,
orange cap 2 doses: 0, 3 w None
12 through 17 y Pfizer-BioNTech,
purple or gray cap 2 doses: 0, 3 w 5 mo after dose 2
18 y or older Pfizer-BioNTech,
purple or gray cap 2 doses: 0, 3 w 5 mo after dose 2
18 y or older Moderna 2 doses: 0, 4 w (100 mcg) 5 mo after dose 2 (50 mcg)
18 y or older Alternate:
Janssen (J&J) one dose 2 mo (8 w) later
COVID-19 recommended schedule for people with moderate to severe immunocompromise ([link removed]) :
Age Range Product Primary Series Booster dose? *
5 through 11 y Pfizer-BioNTech,
orange cap 3 doses: 0, 3 w, 7 w None
12 through 17 y Pfizer-BioNTech,
purple or gray cap 3 doses: 0, 3 w, 7 w 5 mo after dose 2
18 y or older Pfizer-BioNTech,
purple or gray cap 3 doses: 0, 3 w, 7 w 5 mo after dose 2
18 y or older Moderna 3 doses: 0, 4 w, 8 w
(100 mcg) 5 mo after dose 2
(50 mcg)
18 y or older Alternate:
Janssen (J&J) one dose 2 mo (8 w) later
* CDC recommends use of the same brand for each dose in the primary series. Any age-appropriate option may be used as the booster dose; mRNA vaccines are preferred.
FDA: EUA Fact Sheets, dates of current versions:
Product For Healthcare Providers For Recipients
Pfizer-BioNTech, 5 through 11 y, orange cap 03 January 2022 ([link removed]) 03 January 2022 ([link removed])
Pfizer-BioNTech, 12+ y, purple cap 03 January 2022 ([link removed]) 03 January 2022 ([link removed])
Pfizer-BioNTech, 12+ y, gray cap 03 January 2022 ([link removed]) 03 January 2022 ([link removed])
Moderna 07 January 2022 ([link removed]) 07 January 2022 ([link removed])
Janssen (J&J) 11 January 2022 ([link removed]) 11 January 2022 ([link removed])
CDC Emergency Use Instructions (EUI) for use of Pfizer-BioNTech mRNA vaccine in people given vaccines not authorized in the United States:
* For Healthcare Providers: 07 January 2022 ([link removed])
* For Recipients: 07 January 2022 ([link removed])
The most current CDC COVID-19 vaccine standing order templates, dated 12 January 2022, are available from Immunize.org’s standing order template ([link removed]) main page.
Related Links:
* CDC: Interim Clinical Considerations ([link removed]) main page
* Immunize.org: Vaccines: COVID-19 ([link removed]) main page
* Immunize.org: Ask the Experts: COVID-19 ([link removed]) web page
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“Effectiveness of a Third Dose of Pfizer-BioNTech and Moderna Vaccines in Preventing COVID-19 Hospitalization among Immunocompetent and Immunocompromised Adults—United States, August–December 2021” published in MMWR
CDC published Effectiveness of a Third Dose of Pfizer-BioNTech and Moderna Vaccines in Preventing COVID-19 Hospitalization among Immunocompetent and Immunocompromised Adults—United States, August–December 2021 ([link removed]) on January 28 in MMWR. The study was performed during August 19–December 15, 2021, a period in which the SARS-CoV-2 Delta variant was predominant. Portions of the abstract appear below.
In a study of hospitalized adults, compared with receipt of 2 mRNA COVID-19 vaccine doses, receipt of a third dose increased vaccine effectiveness against hospitalization among adults without and with immunocompromising conditions, from 82% to 97% and from 69% to 88%, respectively. ...
Administration of a third COVID-19 mRNA vaccine dose as part of a primary series among immunocompromised adults, or as a booster dose among immunocompetent adults, provides improved protection against COVID-19–associated hospitalization.
Access the MMWR article in HTML ([link removed]) or PDF ([link removed]) .
Related Link
* MMWR's main page ([link removed]) provides access to MMWR Weekly and its companion publications
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Influenza activity expected to continue for several more weeks; keep vaccinating
Influenza Surveillance
For week 3, ending on January 22, CDC's Weekly U.S. Influenza Surveillance Report, FluView ([link removed]) shows that influenza virus circulation has remained at similar levels during the past 2 weeks, while overall levels of respiratory illness have declined. So far this season, five influenza-associated deaths among children have been reported. While influenza activity is difficult to predict, it is expected to continue for several more weeks and vaccination efforts should continue.
[link removed]
Influenza Vaccination Dashboard
CDC's new Weekly Flu Vaccination Dashboard ([link removed]) shares preliminary vaccination data. This week’s key fact: by the end of December 2021, influenza vaccination rates among pregnant people age 18 through 49 were 11.3 percentage points lower compared with last season at the end of December 2020 (50.0% compared to 61.3%). Racial and ethnic disparities in vaccination are wide: coverage as of December 2021 is 22.7 percentage points lower for non-Hispanic Black pregnant people than non-Hispanic White pregnant people (28.2% compared to 50.9%).
CDC recommends everyone age 6 months and older get an annual flu vaccine. Influenza and COVID-19 vaccines may be given at the same visit, if needed. COVID-19 vaccination alone provides no protection from influenza or any other respiratory virus.
Vaccine Finder
If you don’t provide influenza vaccine at your site, please strongly recommend vaccination and refer people to sites that do vaccinate. Use VaccineFinder, a user-friendly website to help people of all ages find influenza, COVID-19, and other vaccines ([link removed]) . Participating providers can update their vaccine inventory estimates on VaccineFinder. For questions or more information, contact [email protected] (mailto:[email protected]) .
Related Links
* CDC: Weekly Flu Vaccination Dashboard ([link removed]) main page
* CDC: FluView ([link removed]) main page
* CDC: Influenza (Flu) ([link removed]) main page
* Immunize.org: free educational materials and patient handouts related to influenza ([link removed])
* Immunize.org: Influenza: Vaccines ([link removed]) main page
* Immunize.org: Ask the Experts: Influenza ([link removed]) main page
* VaccineFinder ([link removed]) website
* Families Fighting Flu: Flu Resources for Healthcare Professionals ([link removed]) main page
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February is National Cancer Prevention Month; arm your patients with HPV and hepatitis B vaccinations in the fight to prevent cancer
February is National Cancer Prevention Month ([link removed]) , a great time to spread the word about the link between viruses and . Each year in the United States, more than 36,000 men and women are diagnosed with cancers associated with human papillomavirus (HPV) infection. Chronic hepatitis B virus infection is an important cause of liver cancer. Vaccination is the simplest, best way to prevent the infections that cause these cancers. Make sure to promote vaccination according to the recommended vaccination schedules ([link removed]) .
[link removed]
View Prevent Cancer Foundation's Think about the Link between Certain Viruses and Cancer ([link removed]) web page for more.
Related Links
* Prevent Cancer Foundation: National Cancer Prevention Month ([link removed]) website
* Immunize.org:Vaccines: Hepatitis B ([link removed]) main page
* Immunize.org: Handouts: Hepatitis B ([link removed]) main page
* Immunize.org:Vaccines: HPV ([link removed]) main page
* Immunize.org: Handouts: HPV ([link removed]) main page
* CDC: How to Prevent Cancer or Find it Early: Vaccines (Shots) ([link removed]) web page
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IZ Express keeps readers up to date on what’s new in vaccines each week; invite your colleagues to subscribe!
IZ Express ([link removed]) , the free weekly e-newsletter produced by Immunize.org, may have a new name and look, but our commitment since 1997 to support you with immunization news and resources is steadfast.
* IZ Express succinctly summarizes each week’s important vaccine developments, including new and updated recommendations from CDC and the latest vaccine decisions by FDA
* IZ Express features newly posted Vaccine Information Statements and their translations, plus education materials from Immunize.org, CDC, AAP, and others
* Subscribers learn about online and in-person educational opportunities, many offering free continuing education credit
We appreciate you as a subscriber! Please encourage co-workers to subscribe to IZ Express ([link removed]) so this invaluable resource arrives in their inbox each Wednesday.
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Spotlight: Check out staff training and in-service resources provided by Immunize.org
In this week’s Spotlight, we summarize resources at Immunize.org ([link removed]) that focus on staff training and in-services.
Our Key Vaccination Resources for Healthcare Professionals ([link removed]) includes an annotated list of key training, education, and reference materials for people who vaccinate or oversee vaccination clinics.
Our Skills Checklist for Vaccine Administration ([link removed]) is a tool to help supervisors assess staff members’ skills regarding vaccine administration.
Our Clinic Tools ([link removed]) main page offers a one-stop source of practical information for immunization providers. You will find “how-to” information about providing vaccinations in a medical office or non-traditional setting.
Our Clinic Tools: Storage and Handling ([link removed]) main page features checklists, “Do Not Unplug” signs, how to avoid errors, temperature logs, storage troubleshooting records, and more. You'll find links to CDC's storage and handling training tools, along with other partner resources.
Our Clinic Tools: Administering Vaccines ([link removed]) main page offers handouts on appropriate injection techniques, information on how to properly deliver intramuscular and subcutaneous injections, medical management of adverse reactions, summaries of vaccine recommendations, and how to use vaccines needing reconstitution.
[link removed]
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Journalists interview Immunize.org experts
Journalists seek out Immunize.org experts to help explain vaccines to the public and policy makers. We help the media understand and communicate the complex work vaccinators do. Here is one of our recent citations.
* CNN: Millions of Routine Vaccinations Have Been Missed amid the COVID-19 Pandemic ([link removed]) (1/27/22)
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Vaccines in the News
These recent articles convey the potential risks of vaccine-preventable diseases and the importance of vaccination.
* New York Times: The World Surpasses 10 Billion Vaccine Doses Administered, but Gaps Persist in Who Gets the Shots ([link removed]) (1/28/22)
* Mayo Clinic: History of Infectious Disease Outbreaks and Vaccines Timeline ([link removed] ) (1/28/22)
* CNBC: COVID Vaccine Skepticism May Be Fueling ‘Worrisome’ Rise in Wider Anti-vax Sentiment, Doctors Say ([link removed]) (1/26/22)
* Nature: Long-COVID Symptoms Less Likely in Vaccinated People, Israeli Data Say ([link removed]) (1/25/22)
* WebMD: Booster Shots 90% Effective at Preventing Omicron Hospitalizations: CDC Data ([link removed]) (1/24/22)
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Immunize.org Pages and Handouts
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Recap: These updated Immunize.org educational materials and web pages for clinicians were released during December and January
IZ Express regularly provides readers with information about Immunize.org’s new and updated educational materials and web pages for healthcare professionals. All Immunize.org materials are free to distribute.
In case you missed them during recent weeks, updates were made to these helpful materials:
Immunize.org Updated Materials for Clinicians
* How to Administer Multiple Intramuscular Vaccines to Adults during One Visit ([link removed])
* Using Standing Orders for Administering Vaccines: What You Should Know ([link removed])
* Dates of Current Vaccine Information Statements (VISs) ([link removed])
* You Must Provide Patients with Vaccine Information Statements (VISs) – It's Federal Law! ([link removed])
Immunize.org Updated Web Pages
* Vaccines: COVID-19 ([link removed])
* Ask the Experts: COVID-19 ([link removed])
* Ask the Experts: HPV ([link removed])
* Ask the Experts: Hepatitis A ([link removed])
* Vaccine Timeline: Historic Dates and Events Related to Vaccines and Immunization ([link removed])
Related Links
* Immunize.org: Handouts ([link removed]) main page to see educational materials sorted by category
* Immunize.org: Ask the Experts ([link removed]) main page to access more than 1,000 questions answered by Immunize.org experts
* Immunize.org: Clinic Tools ([link removed]) main page and its nine subtopics
* Immunize.org: Educational Materials for Patients and Staff ([link removed]) —an alphabetical list of more than 230 ready-to-print staff educational materials and patient handouts
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Vaccine Information Statements
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Recap: These new VISs and VIS translations were released during December and January
IZ Express regularly provides readers with information about Vaccine Information Statements (VISs) and translations of VISs.
CDC released updated final versions of 14 VISs in August, four more in October, and the new Dengue Vaccine ([link removed]) VIS in December. During December and January, updated VIS translations were posted in:
* Karen ([link removed])
* Spanish ([link removed]) (Dengue VIS only)
* Turkish ([link removed])
Additionally, two Immunize.org handouts related to VISs were updated:
* Dates of Current Vaccine Information Statements (VISs) ([link removed])
* You Must Provide Patients with Vaccine Information Statements (VISs) – It’s Federal Law! ([link removed])
Related Links
* Immunize.org: Vaccine Information Statement ([link removed]) main page for VISs in 46 languages
* Immunize.org: Dates of Current Vaccine Information Statements ([link removed]) (PDF)
* CDC: What’s New with VISs ([link removed]) web page
* CDC: Current VISs ([link removed]) web page
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Featured Resources
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Asian Liver Center launches new “Hep B Moms” website with resources to prevent mother-to-child hepatitis B transmission
The Asian Liver Center at Stanford University launched its HepB Moms website ([link removed]) this month. The site is dedicated to providing resources to protect women and children from hepatitis B and to eliminate mother-to-child transmission. Resources are available for both the public and providers.
[link removed]
Share this resource with women who have hepatitis B and with healthcare professionals who care for pregnant individuals.
Related Links
* CDC: Recommendations for Hepatitis B Vaccination of Adults 19 through 59 Years of Age ([link removed]) , approved by ACIP at their November 2021 meeting
* Immunize.org:Vaccines: Hepatitis B ([link removed]) main page
* Immunize.org: Handouts: Hepatitis B main page ([link removed]) main page
* Immunize.org: Hepatitis B: Questions and Answers ([link removed]) (PDF)
* Immunize.org: Hepatitis B Vaccine Information Statement ([link removed]) (PDF)
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National Association of School Nurses journal publishes supplement with five articles on school-located vaccination clinics
The National Association of School Nurses (NASN) and the Association of Immunization Managers (AIM) have collaborated on “School-Located Vaccination (SLV) Clinics in the Era of COVID-19,” a supplemental issue of the NASN School Nurse ([link removed]) journal. It can be viewed with free digital access for the next year.
[link removed]
View the supplemental issue of the NASN School Nurse ([link removed]) .
Related Links
* Immunize.org: Mass Vaccination Resources ([link removed]) main page
* CDC: Considerations for Planning School-Located Vaccination Clinics ([link removed]) web page
* CDC: Customizable Content for School-Located Vaccination Clinics ([link removed]) web page
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CHOP’s Vaccine Education Center presents new video series featuring Paul Offit, MD, answering common questions related to vaccines
The Vaccine Education Center (VEC) ([link removed]) at Children's Hospital of Philadelphia (CHOP) offers a new series of short videos, Dr. Offit Answers Your Questions @ Vaccines ([link removed]) , that can be accessed on YouTube. The video series will address common vaccine questions being asked by interested parents and family members.
In the first video in the series, Dr. Offit answers questions about common side effects of vaccines and what they mean.
[link removed]
Related Links
* CHOP VEC: Dr. Offit Answers Your Questions @ Vaccines ([link removed]) YouTube playlist
* CHOP VEC: Videos and DVDs ([link removed]) main page
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CHOP's Vaccine Education Center revises its COVID-19 Vaccines Q&A handout for the public
The Vaccine Education Center (VEC) ([link removed]) at Children's Hospital of Philadelphia (CHOP) recently revised its COVID-19 Vaccines: What You Should Know ([link removed]) Q&A handout for the public. The revised version includes updated age and booster recommendations.
View the handout in both English ([link removed]) and Spanish ([link removed]) .
[link removed]
All Q&A sheets can be photocopied for sharing with patients and families for free, or ordered from VEC ([link removed]) in packs of 50 at a nominal cost. Links can be added to websites or shared on social media platforms.
Related Links
* CHOP VEC: Vaccine- and Vaccine Safety-Related Q&A Sheets ([link removed]) main page
* CHOP VEC: My COVID-19 Vaccine Experience ([link removed]) video
* CHOP: Vaccine Education Center ([link removed]) website
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Voices for Vaccines releases podcast with Patsy Stinchfield, NP, answering parents' questions on kids and COVID-19 vaccines
Voices for Vaccines (VFV) has posted a new entry in its Vax Talk podcast series: Kids and COVID Vaccines ([link removed]) . A description from the VFV web page appears below.
Parents have a lot of questions about COVID vaccines and their kids, so we invited those parents to a Zoom chat with nationally-known expert and pediatric nurse practitioner, Patsy Stinchfield. They got a chance to ask their questions, and we all got answers.
We begin with a discussion between Nathan and Karen on Dr. Peter Hotez and saving the world through equitable, accessible, and affordable vaccination.
[link removed]
Voices for Vaccines is a national organization of parents and others dedicated to raising the level of the voices of immunization supporters. VFV invites everyone who values vaccines to become a member, use VFV tools in their own community, and get involved with VFV ([link removed]) .
Related Links
* Voices for Vaccines Tools ([link removed]) main page
* Voices for Vaccines podcast page ([link removed])
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Newly updated “65+ Flu Defense” website offers resources for healthcare professionals serving older adults
Confident recommendations for influenza vaccine from healthcare providers are powerfully persuasive. To assist you in maximizing protection for your patients, Immunize.org, in collaboration with Seqirus, has updated the "65+ Flu Defense" website at www.influenza-defense.org ([link removed]).
A new fact sheet on the site, ([link removed]) The Importance of Preventing Influenza during a Pandemic, ([link removed]) [link removed] responses to help guide discussions with patients on the increased importance of flu vaccination during the COVID-19 pandemic. Age increases risks associated with COVID-19 infection including hospitalization and death. Preliminary studies suggest coinfection with influenza B and SARS-CoV-2 may elevate the risk of poor outcomes.
[link removed]
This helpful site includes information, tools, and tips for communicating with these adults about the scope and severity of influenza, for example:
* Influenza in Adults 65+: The Facts ([link removed])
* Influenza Vaccination: Questions Patients Age 65 and Older Frequently Ask Their HCP ([link removed])
Check out the updated "65+ Flu Defense" website at www.influenza-defense.org ([link removed]) to assist your efforts in protecting this vulnerable population.
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FREE! Immunize.org offers "Me Vacuné Contra el COVID-19” and “I Got My COVID-19 Vaccine” buttons and stickers. Free shipping! Available in English and Spanish.
As COVID-19 vaccination programs vaccinate children age 5 through 11 years and offer booster doses to more people, now is the time to stock up on Immunize.org’s FREE “I Got My COVID-19 Vaccine” buttons and stickers ([link removed]) , provided at no cost for product or shipping thanks to support from CDC. Available in English and Spanish, these buttons and stickers are perfect for people of all ages who want to show their confidence in COVID-19 vaccination.
Click the picture to place your order now:
[link removed]
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FREE! Order Immunize.org’s popular red "Vacuna Contra LA GRIPE" buttons and stickers. Free shipping! Available in Spanish.
Immunize.org still has a limited supply of our popular “Vacuna Contra LA GRIPE” buttons and stickers ([link removed]) , available at no charge for product or shipping, thanks to funding from Seqirus. Now more than ever, it is important to step up our efforts to eliminate disparities in influenza vaccination rates. This bright red Spanish button can help.
Click the picture to place your order now:
[link removed]
“FLU VACCINE” BUTTONS
The buttons measure 1.25" across and are delivered in bags of 10 buttons per bag.
“FLU VACCINE” STICKERS
Measuring 1.5" across, these stickers adhere well to clothing and have an easy-peel-off backing.
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Explore the updated www.Give2MenACWY.org website to increase coverage for the MenACWY booster and other adolescent vaccinations
Immunize.org's www.Give2MenACWY.org ([link removed]) website promotes the importance of adolescent vaccination, including administering the recommended booster dose of MenACWY vaccine at age 16. Many teens are behind on vaccines because of the pandemic, so adolescent vaccination is more important than ever.
Original materials on this colorful website for healthcare professionals have been updated to incorporate the 2020 ACIP meningococcal vaccine recommendations ([link removed]) and the most recent vaccine coverage statistics from CDC’s National Immunization Survey–Teen (NIS–Teen). One particularly popular resource on the site is the updated Algorithm for MenACWY Immunization in Adolescents 11–18 Years of Age ([link removed]).
[link removed]
The website is divided into five easy-to-access sections:
* Vaccinate Teens ([link removed]) – Teen vaccination schedules and tips for improving adolescent vaccination rates
* Give 2 Doses ([link removed]) – Tools to help improve second dose coverage of MenACWY vaccine
* 16-Year-Old Visit ([link removed]) – Resources to help providers and patients remember the important vaccines recommended for 16-year-olds
* Tools for Providers ([link removed]) – Tools to explain meningococcal ACWY vaccine recommendations and improve coverage for all adolescent vaccines
* Resources ([link removed]) – Links to print materials ([link removed]) , organizations ([link removed]) involved in adolescent vaccination, personal stories ([link removed]) about the importance of vaccination, and additional resources ([link removed]) of interest
The site also categorizes materials ([link removed]) according to whether they are primarily of interest to providers, to adolescents, or to parents.
Visit Give2MenACWY.org ([link removed]) and enjoy browsing (and deploying) its bountiful resources.
Related Links
* Give2MenACWY.org ([link removed]) website
* Algorithm for MenACWY Immunization in Adolescents 11–18 Years of Age ([link removed])
* MenACWY: You're Not Done If You Give Just One: Give 2 Doses to Strengthen Protection ([link removed])
* Recommending MenACWY: What to Say and How to Say It ([link removed])
* Top 10 Ways to Improve Adolescent Immunization Rates ([link removed])
* Developing an Immunization Culture in Your Office ([link removed])
* Know Your Rates: Measuring Immunization Success in Your Practice ([link removed])
* Immunize.org: You're 16: We Recommend These Vaccines for You ([link removed])
* CDC: 2020 ACIP Meningococcal Vaccine Recommendations ([link removed])
* CDC: National, Regional, State, and Selected Local Area Vaccination Coverage among Adolescents Aged 13–17 Years — United States, 2020 ([link removed])
* CDC: Adolescent Vaccination Coverage in the U.S. ([link removed])
* Immunize.org: Dear Colleague Letter: 16-Year-Old Patients: Make Sure They Receive Their Annual Well Visit and Vaccinations ([link removed]) – signed by six medical societies
* Immunize.org: Ask the Experts: Meningococcal ACWY ([link removed])
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Notable Publications
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“A Prospective Cohort Study of COVID-19 Vaccination, SARS-CoV-2 Infection, and Fertility” published in American Journal of Epidemiology
In the January 20 issue, American Journal of Epidemiology published A Prospective Cohort Study of COVID-19 Vaccination, SARS-CoV-2 Infection, and Fertility ([link removed]) . A portion of the abstract appears below.
Some reproductive-aged individuals remain unvaccinated against COVID-19 due to concerns about potential adverse effects on fertility. We examined the associations of COVID-19 vaccination and SARS-CoV-2 infection with fertility among couples trying to conceive spontaneously using data from an internet-based preconception cohort study. We enrolled 2,126 self-identified females residing in the U.S. or Canada during December 2020–September 2021 and followed them through November 2021. Participants completed questionnaires every 8 weeks on sociodemographics, lifestyle, medical factors, and partner information.
The research team found no statistically significant association between the probability of conception and:
* COVID-19 vaccination of either partner
* SARS-CoV-2 infection in either partner
Related Link
* NIH news release: COVID-19 Vaccination Does Not Reduce Chances of Conception, Study Suggests ([link removed]) (1/20/22)
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"Homologous and Heterologous COVID-19 Booster Vaccinations" published in NEJM
In the January 26 issue, the New England Journal of Medicine published Homologous and Heterologous COVID-19 Booster Vaccinations ([link removed]) . If a person received a booster with the same brand of COVID-19 vaccine they received for the first two doses it was considered “homologous;” if they received a different brand for the booster it was considered “heterologous.” A portion of the article appears below.
We report the interim findings from this open-label clinical trial examining the safety, reactogenicity, and immunogenicity of SARS-CoV-2 booster vaccines in healthy adults who had previously received an EUA vaccine series. All booster vaccines were immunogenic in the participants regardless of which primary EUA regimen they had received ... The factor increases from prebooster levels in both binding and neutralizing antibody titers were similar or greater after heterologous boosting than after homologous boosting. Reactogenicity was similar to that described in previous evaluations of mRNA-1273, Ad26.COV2.S, and BNT162b2 vaccines and did not differ between heterologous and homologous boosters. No safety concerns were identified.
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MMWR Recap: Articles regarding COVID-19 vaccine effectiveness against death and hospitalization
CDC recently published several articles first distributed as MMWR Early Releases:
* COVID-19 Incidence and Death Rates among Unvaccinated and Fully Vaccinated Adults with and without Booster Doses during Periods of Delta and Omicron Variant Emergence—25 U.S. Jurisdictions, April 4–December 25, 2021 (MMWR, January 28, HTML ([link removed]) or PDF ([link removed]) )
* Effectiveness of a Third Dose of mRNA Vaccines against COVID-19–Associated Emergency Department and Urgent Care Encounters and Hospitalizations among Adults during Periods of Delta and Omicron Variant Predominance—VISION Network, 10 States, August 2021–January 2022 (MMWR, January 28, HTML ([link removed]) or PDF ([link removed]) )
Related Link
* MMWR ([link removed]) main page provides access to MMWR Weekly and its companion publications
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Upcoming Events
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February 10–11: National Vaccine Advisory Committee meeting; watch virtually
National Vaccine Advisory Committee (NVAC) meetings ([link removed]) are held three times a year. The meetings cover the most recent and pressing topics affecting the vaccine enterprise. NVAC is scheduled to meet February 10–11 and the meetings can be viewed virtually. The meeting is open to the public. Pre-registration is required for both public attendance and comment.
See the February 10–11 NVAC Meeting Materials ([link removed]) web page for more information.
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For more upcoming events, visit our Calendar of Events ([link removed]) .
Editorial Information
Editor-in-Chief
Kelly L. Moore, MD, MPH
Managing Editor
John D. Grabenstein, RPh, PhD
Associate Editor
Sharon G. Humiston, MD, MPH
Writer/Publication Coordinator
Taryn Chapman, MS
Courtnay Londo, MA
Style and Copy Editor
Marian Deegan, JD
Web Edition Managers
Arkady Shakhnovich
Jermaine Royes
Contributing Writer
Laurel H. Wood, MPA
Technical Reviewer
Robin VanOss
About IZ Express
Immunize.org welcomes redistribution of this issue of IZ Express or selected articles.
When you do so, please add a note that Immunize.org is the source of the material and provide a link to this issue ([link removed]) .
IZ Express is supported in part by Grant No. 1NH23IP922654 from the National Center for Immunization and Respiratory Diseases, CDC. Its contents are solely the responsibility of Immunize.org and do not necessarily represent the official views of CDC.
IZ Express Disclaimer ([link removed])
ISSN: Pending
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Issue 1,614: February 2, 2022 Formerly IAC Express
Top Stories
* “Use of 15-Valent Pneumococcal Conjugate Vaccine and 20-Valent Pneumococcal Conjugate Vaccine among U.S. Adults: Updated Recommendations of the Advisory Committee on Immunization Practices—United States, 2022” published in MMWR
* Immunize.org introduces new, print-ready patient handout "Not Sure If You Can Get an Influenza Vaccine?"
* Are you using the most current COVID-19 vaccination schedules? Check these tables to be sure.
* “Effectiveness of a Third Dose of Pfizer-BioNTech and Moderna Vaccines in Preventing COVID-19 Hospitalization among Immunocompetent and Immunocompromised Adults—United States, August–December 2021” published in MMWR
* Influenza activity expected to continue for several more weeks; keep vaccinating
* February is National Cancer Prevention Month; arm your patients with HPV and hepatitis B vaccinations in the fight to prevent cancer
* IZ Express keeps readers up to date on what’s new in vaccines each week; invite your colleagues to subscribe!
* Spotlight: Check out staff training and in-service resources provided by Immunize.org
* Journalists interview Immunize.org experts
* Vaccines in the News
Immunize.org Pages and Handouts
* Recap: These updated Immunize.org educational materials and web pages for clinicians were released during December and January
Vaccine Information Statements
* Recap: These new VISs and VIS translations were released during December and January
Featured Resources
* Asian Liver Center launches new “Hep B Moms” website with resources to prevent mother-to-child hepatitis B transmission
* National Association of School Nurses journal publishes supplement with five articles on school-located vaccination clinics
* CHOP’s Vaccine Education Center presents new video series featuring Paul Offit, MD, answering common questions related to vaccines
* CHOP's Vaccine Education Center revises its COVID-19 Vaccines Q&A handout for the public
* Voices for Vaccines releases podcast with Patsy Stinchfield, NP, answering parents' questions on kids and COVID-19 vaccines
* Newly updated “65+ Flu Defense” website offers resources for healthcare professionals serving older adults
* FREE! Immunize.org offers "Me Vacuné Contra el COVID-19” and “I Got My COVID-19 Vaccine” buttons and stickers. Free shipping! Available in English and Spanish.
* FREE! Order Immunize.org’s popular red "Vacuna Contra LA GRIPE" buttons and stickers. Free shipping! Available in Spanish.
* Explore the updated www.Give2MenACWY.org website to increase coverage for the MenACWY booster and other adolescent vaccinations
Notable Publications
* “A Prospective Cohort Study of COVID-19 Vaccination, SARS-CoV-2 Infection, and Fertility” published in American Journal of Epidemiology
* "Homologous and Heterologous COVID-19 Booster Vaccinations" published in NEJM
* MMWR Recap: Articles regarding COVID-19 vaccine effectiveness against death and hospitalization
Upcoming Events
* February 10–11: National Vaccine Advisory Committee meeting; watch virtually
Editorial Information (#Editorial)
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Top Stories
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“Use of 15-Valent Pneumococcal Conjugate Vaccine and 20-Valent Pneumococcal Conjugate Vaccine among U.S. Adults: Updated Recommendations of the Advisory Committee on Immunization Practices—United States, 2022” published in MMWR
CDC published Use of 15-Valent Pneumococcal Conjugate Vaccine and 20-Valent Pneumococcal Conjugate Vaccine among U.S. Adults: Updated Recommendations of the Advisory Committee on Immunization Practices—United States, 2022 ([link removed]) on January 28 in MMWR. A summary appears below.
Pneumococcal vaccination helps prevent serious diseases, like pneumonia, meningitis, and bloodstream infections. Two pneumococcal conjugate vaccines, PCV15 and PCV20, were licensed in 2021. Now there are updated pneumococcal vaccine recommendations for adults 19 years or older. CDC recommends adults 65 years of age or older who have not previously received a pneumococcal conjugate vaccine or whose previous vaccination history is unknown should receive either PCV20 or PCV15. If PCV15 is used, this should be followed by a dose of pneumococcal polysaccharide vaccine (PPSV23). Adults ages 19 through 64 years with certain underlying medical conditions or other risk factors who have not previously received a pneumococcal conjugate vaccine or whose previous vaccination history is unknown should receive either PCV20 or PCV15. If PCV15 is used, this should be followed by a dose of PPSV23.
The new recommendations are summarized in Table 1 of the MMWR article ([link removed]) .
Access the MMWR article in HTML ([link removed]) or PDF ([link removed]) .
Related Link
* MMWR's main page ([link removed]) provides access to MMWR Weekly and its companion publications
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Immunize.org introduces new, print-ready patient handout "Not Sure If You Can Get an Influenza Vaccine?"
In recent years, contraindications and precautions for influenza vaccination have been updated, expanding our ability to protect more people from serious influenza illness. However, some people mistakenly believe that they should not get an influenza vaccination due to outdated or inaccurate understanding of the risks and benefits of vaccination. To address this, Immunize.org has introduced a new patient handout Not Sure If You Can Get an Influenza Vaccine? ([link removed]) This handout, ideally printed as a two-sided, single page, addresses a variety of concerns (e.g., egg allergy, history of Guillain-Barre syndrome, pregnancy, and a weakened immune system).
[link removed] [link removed]
Related Links
* Immunize.org: Handouts: Influenza ([link removed]) main page
* Immunize.org: Handouts ([link removed]) main page to see educational materials sorted by category
* Immunize.org: Ask the Experts: Influenza ([link removed]) main page
* Immunize.org: Educational Materials for Patients and Staff ([link removed]) —an alphabetical list of more than 230 ready-to-print staff educational materials and patient handouts
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Are you using the most current COVID-19 vaccination schedules? Check these tables to be sure.
It is a challenge to keep up with the frequent adjustments to COVID-19 vaccination schedules. Review these tables to be sure you are following the latest version (last updated by CDC on January 7) and that you are using the current Emergency Use Authorization (EUA) Fact Sheets for healthcare providers and vaccine recipients. Changes made since January 1 are noted in bold print. Moderna and Pfizer-BioNTech mRNA vaccines are preferred, except when mRNA vaccine is contraindicated or when the patient wants Janssen (Johnson & Johnson, J&J) vaccine after being informed of risks and benefits.
COVID-19 recommended schedule for the general population ([link removed]) (y = years, w = weeks, mo = months):
Age Range Product Primary Series Booster dose? *
5 through 11 y Pfizer-BioNTech,
orange cap 2 doses: 0, 3 w None
12 through 17 y Pfizer-BioNTech,
purple or gray cap 2 doses: 0, 3 w 5 mo after dose 2
18 y or older Pfizer-BioNTech,
purple or gray cap 2 doses: 0, 3 w 5 mo after dose 2
18 y or older Moderna 2 doses: 0, 4 w (100 mcg) 5 mo after dose 2 (50 mcg)
18 y or older Alternate:
Janssen (J&J) one dose 2 mo (8 w) later
COVID-19 recommended schedule for people with moderate to severe immunocompromise ([link removed]) :
Age Range Product Primary Series Booster dose? *
5 through 11 y Pfizer-BioNTech,
orange cap 3 doses: 0, 3 w, 7 w None
12 through 17 y Pfizer-BioNTech,
purple or gray cap 3 doses: 0, 3 w, 7 w 5 mo after dose 2
18 y or older Pfizer-BioNTech,
purple or gray cap 3 doses: 0, 3 w, 7 w 5 mo after dose 2
18 y or older Moderna 3 doses: 0, 4 w, 8 w
(100 mcg) 5 mo after dose 2
(50 mcg)
18 y or older Alternate:
Janssen (J&J) one dose 2 mo (8 w) later
* CDC recommends use of the same brand for each dose in the primary series. Any age-appropriate option may be used as the booster dose; mRNA vaccines are preferred.
FDA: EUA Fact Sheets, dates of current versions:
Product For Healthcare Providers For Recipients
Pfizer-BioNTech, 5 through 11 y, orange cap 03 January 2022 ([link removed]) 03 January 2022 ([link removed])
Pfizer-BioNTech, 12+ y, purple cap 03 January 2022 ([link removed]) 03 January 2022 ([link removed])
Pfizer-BioNTech, 12+ y, gray cap 03 January 2022 ([link removed]) 03 January 2022 ([link removed])
Moderna 07 January 2022 ([link removed]) 07 January 2022 ([link removed])
Janssen (J&J) 11 January 2022 ([link removed]) 11 January 2022 ([link removed])
CDC Emergency Use Instructions (EUI) for use of Pfizer-BioNTech mRNA vaccine in people given vaccines not authorized in the United States:
* For Healthcare Providers: 07 January 2022 ([link removed])
* For Recipients: 07 January 2022 ([link removed])
The most current CDC COVID-19 vaccine standing order templates, dated 12 January 2022, are available from Immunize.org’s standing order template ([link removed]) main page.
Related Links:
* CDC: Interim Clinical Considerations ([link removed]) main page
* Immunize.org: Vaccines: COVID-19 ([link removed]) main page
* Immunize.org: Ask the Experts: COVID-19 ([link removed]) web page
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“Effectiveness of a Third Dose of Pfizer-BioNTech and Moderna Vaccines in Preventing COVID-19 Hospitalization among Immunocompetent and Immunocompromised Adults—United States, August–December 2021” published in MMWR
CDC published Effectiveness of a Third Dose of Pfizer-BioNTech and Moderna Vaccines in Preventing COVID-19 Hospitalization among Immunocompetent and Immunocompromised Adults—United States, August–December 2021 ([link removed]) on January 28 in MMWR. The study was performed during August 19–December 15, 2021, a period in which the SARS-CoV-2 Delta variant was predominant. Portions of the abstract appear below.
In a study of hospitalized adults, compared with receipt of 2 mRNA COVID-19 vaccine doses, receipt of a third dose increased vaccine effectiveness against hospitalization among adults without and with immunocompromising conditions, from 82% to 97% and from 69% to 88%, respectively. ...
Administration of a third COVID-19 mRNA vaccine dose as part of a primary series among immunocompromised adults, or as a booster dose among immunocompetent adults, provides improved protection against COVID-19–associated hospitalization.
Access the MMWR article in HTML ([link removed]) or PDF ([link removed]) .
Related Link
* MMWR's main page ([link removed]) provides access to MMWR Weekly and its companion publications
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Influenza activity expected to continue for several more weeks; keep vaccinating
Influenza Surveillance
For week 3, ending on January 22, CDC's Weekly U.S. Influenza Surveillance Report, FluView ([link removed]) shows that influenza virus circulation has remained at similar levels during the past 2 weeks, while overall levels of respiratory illness have declined. So far this season, five influenza-associated deaths among children have been reported. While influenza activity is difficult to predict, it is expected to continue for several more weeks and vaccination efforts should continue.
[link removed]
Influenza Vaccination Dashboard
CDC's new Weekly Flu Vaccination Dashboard ([link removed]) shares preliminary vaccination data. This week’s key fact: by the end of December 2021, influenza vaccination rates among pregnant people age 18 through 49 were 11.3 percentage points lower compared with last season at the end of December 2020 (50.0% compared to 61.3%). Racial and ethnic disparities in vaccination are wide: coverage as of December 2021 is 22.7 percentage points lower for non-Hispanic Black pregnant people than non-Hispanic White pregnant people (28.2% compared to 50.9%).
CDC recommends everyone age 6 months and older get an annual flu vaccine. Influenza and COVID-19 vaccines may be given at the same visit, if needed. COVID-19 vaccination alone provides no protection from influenza or any other respiratory virus.
Vaccine Finder
If you don’t provide influenza vaccine at your site, please strongly recommend vaccination and refer people to sites that do vaccinate. Use VaccineFinder, a user-friendly website to help people of all ages find influenza, COVID-19, and other vaccines ([link removed]) . Participating providers can update their vaccine inventory estimates on VaccineFinder. For questions or more information, contact [email protected] (mailto:[email protected]) .
Related Links
* CDC: Weekly Flu Vaccination Dashboard ([link removed]) main page
* CDC: FluView ([link removed]) main page
* CDC: Influenza (Flu) ([link removed]) main page
* Immunize.org: free educational materials and patient handouts related to influenza ([link removed])
* Immunize.org: Influenza: Vaccines ([link removed]) main page
* Immunize.org: Ask the Experts: Influenza ([link removed]) main page
* VaccineFinder ([link removed]) website
* Families Fighting Flu: Flu Resources for Healthcare Professionals ([link removed]) main page
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February is National Cancer Prevention Month; arm your patients with HPV and hepatitis B vaccinations in the fight to prevent cancer
February is National Cancer Prevention Month ([link removed]) , a great time to spread the word about the link between viruses and . Each year in the United States, more than 36,000 men and women are diagnosed with cancers associated with human papillomavirus (HPV) infection. Chronic hepatitis B virus infection is an important cause of liver cancer. Vaccination is the simplest, best way to prevent the infections that cause these cancers. Make sure to promote vaccination according to the recommended vaccination schedules ([link removed]) .
[link removed]
View Prevent Cancer Foundation's Think about the Link between Certain Viruses and Cancer ([link removed]) web page for more.
Related Links
* Prevent Cancer Foundation: National Cancer Prevention Month ([link removed]) website
* Immunize.org:Vaccines: Hepatitis B ([link removed]) main page
* Immunize.org: Handouts: Hepatitis B ([link removed]) main page
* Immunize.org:Vaccines: HPV ([link removed]) main page
* Immunize.org: Handouts: HPV ([link removed]) main page
* CDC: How to Prevent Cancer or Find it Early: Vaccines (Shots) ([link removed]) web page
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IZ Express keeps readers up to date on what’s new in vaccines each week; invite your colleagues to subscribe!
IZ Express ([link removed]) , the free weekly e-newsletter produced by Immunize.org, may have a new name and look, but our commitment since 1997 to support you with immunization news and resources is steadfast.
* IZ Express succinctly summarizes each week’s important vaccine developments, including new and updated recommendations from CDC and the latest vaccine decisions by FDA
* IZ Express features newly posted Vaccine Information Statements and their translations, plus education materials from Immunize.org, CDC, AAP, and others
* Subscribers learn about online and in-person educational opportunities, many offering free continuing education credit
We appreciate you as a subscriber! Please encourage co-workers to subscribe to IZ Express ([link removed]) so this invaluable resource arrives in their inbox each Wednesday.
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Spotlight: Check out staff training and in-service resources provided by Immunize.org
In this week’s Spotlight, we summarize resources at Immunize.org ([link removed]) that focus on staff training and in-services.
Our Key Vaccination Resources for Healthcare Professionals ([link removed]) includes an annotated list of key training, education, and reference materials for people who vaccinate or oversee vaccination clinics.
Our Skills Checklist for Vaccine Administration ([link removed]) is a tool to help supervisors assess staff members’ skills regarding vaccine administration.
Our Clinic Tools ([link removed]) main page offers a one-stop source of practical information for immunization providers. You will find “how-to” information about providing vaccinations in a medical office or non-traditional setting.
Our Clinic Tools: Storage and Handling ([link removed]) main page features checklists, “Do Not Unplug” signs, how to avoid errors, temperature logs, storage troubleshooting records, and more. You'll find links to CDC's storage and handling training tools, along with other partner resources.
Our Clinic Tools: Administering Vaccines ([link removed]) main page offers handouts on appropriate injection techniques, information on how to properly deliver intramuscular and subcutaneous injections, medical management of adverse reactions, summaries of vaccine recommendations, and how to use vaccines needing reconstitution.
[link removed]
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Journalists interview Immunize.org experts
Journalists seek out Immunize.org experts to help explain vaccines to the public and policy makers. We help the media understand and communicate the complex work vaccinators do. Here is one of our recent citations.
* CNN: Millions of Routine Vaccinations Have Been Missed amid the COVID-19 Pandemic ([link removed]) (1/27/22)
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Vaccines in the News
These recent articles convey the potential risks of vaccine-preventable diseases and the importance of vaccination.
* New York Times: The World Surpasses 10 Billion Vaccine Doses Administered, but Gaps Persist in Who Gets the Shots ([link removed]) (1/28/22)
* Mayo Clinic: History of Infectious Disease Outbreaks and Vaccines Timeline ([link removed] ) (1/28/22)
* CNBC: COVID Vaccine Skepticism May Be Fueling ‘Worrisome’ Rise in Wider Anti-vax Sentiment, Doctors Say ([link removed]) (1/26/22)
* Nature: Long-COVID Symptoms Less Likely in Vaccinated People, Israeli Data Say ([link removed]) (1/25/22)
* WebMD: Booster Shots 90% Effective at Preventing Omicron Hospitalizations: CDC Data ([link removed]) (1/24/22)
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Immunize.org Pages and Handouts
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Recap: These updated Immunize.org educational materials and web pages for clinicians were released during December and January
IZ Express regularly provides readers with information about Immunize.org’s new and updated educational materials and web pages for healthcare professionals. All Immunize.org materials are free to distribute.
In case you missed them during recent weeks, updates were made to these helpful materials:
Immunize.org Updated Materials for Clinicians
* How to Administer Multiple Intramuscular Vaccines to Adults during One Visit ([link removed])
* Using Standing Orders for Administering Vaccines: What You Should Know ([link removed])
* Dates of Current Vaccine Information Statements (VISs) ([link removed])
* You Must Provide Patients with Vaccine Information Statements (VISs) – It's Federal Law! ([link removed])
Immunize.org Updated Web Pages
* Vaccines: COVID-19 ([link removed])
* Ask the Experts: COVID-19 ([link removed])
* Ask the Experts: HPV ([link removed])
* Ask the Experts: Hepatitis A ([link removed])
* Vaccine Timeline: Historic Dates and Events Related to Vaccines and Immunization ([link removed])
Related Links
* Immunize.org: Handouts ([link removed]) main page to see educational materials sorted by category
* Immunize.org: Ask the Experts ([link removed]) main page to access more than 1,000 questions answered by Immunize.org experts
* Immunize.org: Clinic Tools ([link removed]) main page and its nine subtopics
* Immunize.org: Educational Materials for Patients and Staff ([link removed]) —an alphabetical list of more than 230 ready-to-print staff educational materials and patient handouts
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Vaccine Information Statements
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Recap: These new VISs and VIS translations were released during December and January
IZ Express regularly provides readers with information about Vaccine Information Statements (VISs) and translations of VISs.
CDC released updated final versions of 14 VISs in August, four more in October, and the new Dengue Vaccine ([link removed]) VIS in December. During December and January, updated VIS translations were posted in:
* Karen ([link removed])
* Spanish ([link removed]) (Dengue VIS only)
* Turkish ([link removed])
Additionally, two Immunize.org handouts related to VISs were updated:
* Dates of Current Vaccine Information Statements (VISs) ([link removed])
* You Must Provide Patients with Vaccine Information Statements (VISs) – It’s Federal Law! ([link removed])
Related Links
* Immunize.org: Vaccine Information Statement ([link removed]) main page for VISs in 46 languages
* Immunize.org: Dates of Current Vaccine Information Statements ([link removed]) (PDF)
* CDC: What’s New with VISs ([link removed]) web page
* CDC: Current VISs ([link removed]) web page
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Featured Resources
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Asian Liver Center launches new “Hep B Moms” website with resources to prevent mother-to-child hepatitis B transmission
The Asian Liver Center at Stanford University launched its HepB Moms website ([link removed]) this month. The site is dedicated to providing resources to protect women and children from hepatitis B and to eliminate mother-to-child transmission. Resources are available for both the public and providers.
[link removed]
Share this resource with women who have hepatitis B and with healthcare professionals who care for pregnant individuals.
Related Links
* CDC: Recommendations for Hepatitis B Vaccination of Adults 19 through 59 Years of Age ([link removed]) , approved by ACIP at their November 2021 meeting
* Immunize.org:Vaccines: Hepatitis B ([link removed]) main page
* Immunize.org: Handouts: Hepatitis B main page ([link removed]) main page
* Immunize.org: Hepatitis B: Questions and Answers ([link removed]) (PDF)
* Immunize.org: Hepatitis B Vaccine Information Statement ([link removed]) (PDF)
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National Association of School Nurses journal publishes supplement with five articles on school-located vaccination clinics
The National Association of School Nurses (NASN) and the Association of Immunization Managers (AIM) have collaborated on “School-Located Vaccination (SLV) Clinics in the Era of COVID-19,” a supplemental issue of the NASN School Nurse ([link removed]) journal. It can be viewed with free digital access for the next year.
[link removed]
View the supplemental issue of the NASN School Nurse ([link removed]) .
Related Links
* Immunize.org: Mass Vaccination Resources ([link removed]) main page
* CDC: Considerations for Planning School-Located Vaccination Clinics ([link removed]) web page
* CDC: Customizable Content for School-Located Vaccination Clinics ([link removed]) web page
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CHOP’s Vaccine Education Center presents new video series featuring Paul Offit, MD, answering common questions related to vaccines
The Vaccine Education Center (VEC) ([link removed]) at Children's Hospital of Philadelphia (CHOP) offers a new series of short videos, Dr. Offit Answers Your Questions @ Vaccines ([link removed]) , that can be accessed on YouTube. The video series will address common vaccine questions being asked by interested parents and family members.
In the first video in the series, Dr. Offit answers questions about common side effects of vaccines and what they mean.
[link removed]
Related Links
* CHOP VEC: Dr. Offit Answers Your Questions @ Vaccines ([link removed]) YouTube playlist
* CHOP VEC: Videos and DVDs ([link removed]) main page
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CHOP's Vaccine Education Center revises its COVID-19 Vaccines Q&A handout for the public
The Vaccine Education Center (VEC) ([link removed]) at Children's Hospital of Philadelphia (CHOP) recently revised its COVID-19 Vaccines: What You Should Know ([link removed]) Q&A handout for the public. The revised version includes updated age and booster recommendations.
View the handout in both English ([link removed]) and Spanish ([link removed]) .
[link removed]
All Q&A sheets can be photocopied for sharing with patients and families for free, or ordered from VEC ([link removed]) in packs of 50 at a nominal cost. Links can be added to websites or shared on social media platforms.
Related Links
* CHOP VEC: Vaccine- and Vaccine Safety-Related Q&A Sheets ([link removed]) main page
* CHOP VEC: My COVID-19 Vaccine Experience ([link removed]) video
* CHOP: Vaccine Education Center ([link removed]) website
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Voices for Vaccines releases podcast with Patsy Stinchfield, NP, answering parents' questions on kids and COVID-19 vaccines
Voices for Vaccines (VFV) has posted a new entry in its Vax Talk podcast series: Kids and COVID Vaccines ([link removed]) . A description from the VFV web page appears below.
Parents have a lot of questions about COVID vaccines and their kids, so we invited those parents to a Zoom chat with nationally-known expert and pediatric nurse practitioner, Patsy Stinchfield. They got a chance to ask their questions, and we all got answers.
We begin with a discussion between Nathan and Karen on Dr. Peter Hotez and saving the world through equitable, accessible, and affordable vaccination.
[link removed]
Voices for Vaccines is a national organization of parents and others dedicated to raising the level of the voices of immunization supporters. VFV invites everyone who values vaccines to become a member, use VFV tools in their own community, and get involved with VFV ([link removed]) .
Related Links
* Voices for Vaccines Tools ([link removed]) main page
* Voices for Vaccines podcast page ([link removed])
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Newly updated “65+ Flu Defense” website offers resources for healthcare professionals serving older adults
Confident recommendations for influenza vaccine from healthcare providers are powerfully persuasive. To assist you in maximizing protection for your patients, Immunize.org, in collaboration with Seqirus, has updated the "65+ Flu Defense" website at www.influenza-defense.org ([link removed]).
A new fact sheet on the site, ([link removed]) The Importance of Preventing Influenza during a Pandemic, ([link removed]) [link removed] responses to help guide discussions with patients on the increased importance of flu vaccination during the COVID-19 pandemic. Age increases risks associated with COVID-19 infection including hospitalization and death. Preliminary studies suggest coinfection with influenza B and SARS-CoV-2 may elevate the risk of poor outcomes.
[link removed]
This helpful site includes information, tools, and tips for communicating with these adults about the scope and severity of influenza, for example:
* Influenza in Adults 65+: The Facts ([link removed])
* Influenza Vaccination: Questions Patients Age 65 and Older Frequently Ask Their HCP ([link removed])
Check out the updated "65+ Flu Defense" website at www.influenza-defense.org ([link removed]) to assist your efforts in protecting this vulnerable population.
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FREE! Immunize.org offers "Me Vacuné Contra el COVID-19” and “I Got My COVID-19 Vaccine” buttons and stickers. Free shipping! Available in English and Spanish.
As COVID-19 vaccination programs vaccinate children age 5 through 11 years and offer booster doses to more people, now is the time to stock up on Immunize.org’s FREE “I Got My COVID-19 Vaccine” buttons and stickers ([link removed]) , provided at no cost for product or shipping thanks to support from CDC. Available in English and Spanish, these buttons and stickers are perfect for people of all ages who want to show their confidence in COVID-19 vaccination.
Click the picture to place your order now:
[link removed]
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FREE! Order Immunize.org’s popular red "Vacuna Contra LA GRIPE" buttons and stickers. Free shipping! Available in Spanish.
Immunize.org still has a limited supply of our popular “Vacuna Contra LA GRIPE” buttons and stickers ([link removed]) , available at no charge for product or shipping, thanks to funding from Seqirus. Now more than ever, it is important to step up our efforts to eliminate disparities in influenza vaccination rates. This bright red Spanish button can help.
Click the picture to place your order now:
[link removed]
“FLU VACCINE” BUTTONS
The buttons measure 1.25" across and are delivered in bags of 10 buttons per bag.
“FLU VACCINE” STICKERS
Measuring 1.5" across, these stickers adhere well to clothing and have an easy-peel-off backing.
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Explore the updated www.Give2MenACWY.org website to increase coverage for the MenACWY booster and other adolescent vaccinations
Immunize.org's www.Give2MenACWY.org ([link removed]) website promotes the importance of adolescent vaccination, including administering the recommended booster dose of MenACWY vaccine at age 16. Many teens are behind on vaccines because of the pandemic, so adolescent vaccination is more important than ever.
Original materials on this colorful website for healthcare professionals have been updated to incorporate the 2020 ACIP meningococcal vaccine recommendations ([link removed]) and the most recent vaccine coverage statistics from CDC’s National Immunization Survey–Teen (NIS–Teen). One particularly popular resource on the site is the updated Algorithm for MenACWY Immunization in Adolescents 11–18 Years of Age ([link removed]).
[link removed]
The website is divided into five easy-to-access sections:
* Vaccinate Teens ([link removed]) – Teen vaccination schedules and tips for improving adolescent vaccination rates
* Give 2 Doses ([link removed]) – Tools to help improve second dose coverage of MenACWY vaccine
* 16-Year-Old Visit ([link removed]) – Resources to help providers and patients remember the important vaccines recommended for 16-year-olds
* Tools for Providers ([link removed]) – Tools to explain meningococcal ACWY vaccine recommendations and improve coverage for all adolescent vaccines
* Resources ([link removed]) – Links to print materials ([link removed]) , organizations ([link removed]) involved in adolescent vaccination, personal stories ([link removed]) about the importance of vaccination, and additional resources ([link removed]) of interest
The site also categorizes materials ([link removed]) according to whether they are primarily of interest to providers, to adolescents, or to parents.
Visit Give2MenACWY.org ([link removed]) and enjoy browsing (and deploying) its bountiful resources.
Related Links
* Give2MenACWY.org ([link removed]) website
* Algorithm for MenACWY Immunization in Adolescents 11–18 Years of Age ([link removed])
* MenACWY: You're Not Done If You Give Just One: Give 2 Doses to Strengthen Protection ([link removed])
* Recommending MenACWY: What to Say and How to Say It ([link removed])
* Top 10 Ways to Improve Adolescent Immunization Rates ([link removed])
* Developing an Immunization Culture in Your Office ([link removed])
* Know Your Rates: Measuring Immunization Success in Your Practice ([link removed])
* Immunize.org: You're 16: We Recommend These Vaccines for You ([link removed])
* CDC: 2020 ACIP Meningococcal Vaccine Recommendations ([link removed])
* CDC: National, Regional, State, and Selected Local Area Vaccination Coverage among Adolescents Aged 13–17 Years — United States, 2020 ([link removed])
* CDC: Adolescent Vaccination Coverage in the U.S. ([link removed])
* Immunize.org: Dear Colleague Letter: 16-Year-Old Patients: Make Sure They Receive Their Annual Well Visit and Vaccinations ([link removed]) – signed by six medical societies
* Immunize.org: Ask the Experts: Meningococcal ACWY ([link removed])
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Notable Publications
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“A Prospective Cohort Study of COVID-19 Vaccination, SARS-CoV-2 Infection, and Fertility” published in American Journal of Epidemiology
In the January 20 issue, American Journal of Epidemiology published A Prospective Cohort Study of COVID-19 Vaccination, SARS-CoV-2 Infection, and Fertility ([link removed]) . A portion of the abstract appears below.
Some reproductive-aged individuals remain unvaccinated against COVID-19 due to concerns about potential adverse effects on fertility. We examined the associations of COVID-19 vaccination and SARS-CoV-2 infection with fertility among couples trying to conceive spontaneously using data from an internet-based preconception cohort study. We enrolled 2,126 self-identified females residing in the U.S. or Canada during December 2020–September 2021 and followed them through November 2021. Participants completed questionnaires every 8 weeks on sociodemographics, lifestyle, medical factors, and partner information.
The research team found no statistically significant association between the probability of conception and:
* COVID-19 vaccination of either partner
* SARS-CoV-2 infection in either partner
Related Link
* NIH news release: COVID-19 Vaccination Does Not Reduce Chances of Conception, Study Suggests ([link removed]) (1/20/22)
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"Homologous and Heterologous COVID-19 Booster Vaccinations" published in NEJM
In the January 26 issue, the New England Journal of Medicine published Homologous and Heterologous COVID-19 Booster Vaccinations ([link removed]) . If a person received a booster with the same brand of COVID-19 vaccine they received for the first two doses it was considered “homologous;” if they received a different brand for the booster it was considered “heterologous.” A portion of the article appears below.
We report the interim findings from this open-label clinical trial examining the safety, reactogenicity, and immunogenicity of SARS-CoV-2 booster vaccines in healthy adults who had previously received an EUA vaccine series. All booster vaccines were immunogenic in the participants regardless of which primary EUA regimen they had received ... The factor increases from prebooster levels in both binding and neutralizing antibody titers were similar or greater after heterologous boosting than after homologous boosting. Reactogenicity was similar to that described in previous evaluations of mRNA-1273, Ad26.COV2.S, and BNT162b2 vaccines and did not differ between heterologous and homologous boosters. No safety concerns were identified.
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MMWR Recap: Articles regarding COVID-19 vaccine effectiveness against death and hospitalization
CDC recently published several articles first distributed as MMWR Early Releases:
* COVID-19 Incidence and Death Rates among Unvaccinated and Fully Vaccinated Adults with and without Booster Doses during Periods of Delta and Omicron Variant Emergence—25 U.S. Jurisdictions, April 4–December 25, 2021 (MMWR, January 28, HTML ([link removed]) or PDF ([link removed]) )
* Effectiveness of a Third Dose of mRNA Vaccines against COVID-19–Associated Emergency Department and Urgent Care Encounters and Hospitalizations among Adults during Periods of Delta and Omicron Variant Predominance—VISION Network, 10 States, August 2021–January 2022 (MMWR, January 28, HTML ([link removed]) or PDF ([link removed]) )
Related Link
* MMWR ([link removed]) main page provides access to MMWR Weekly and its companion publications
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Upcoming Events
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February 10–11: National Vaccine Advisory Committee meeting; watch virtually
National Vaccine Advisory Committee (NVAC) meetings ([link removed]) are held three times a year. The meetings cover the most recent and pressing topics affecting the vaccine enterprise. NVAC is scheduled to meet February 10–11 and the meetings can be viewed virtually. The meeting is open to the public. Pre-registration is required for both public attendance and comment.
See the February 10–11 NVAC Meeting Materials ([link removed]) web page for more information.
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For more upcoming events, visit our Calendar of Events ([link removed]) .
Editorial Information
Editor-in-Chief
Kelly L. Moore, MD, MPH
Managing Editor
John D. Grabenstein, RPh, PhD
Associate Editor
Sharon G. Humiston, MD, MPH
Writer/Publication Coordinator
Taryn Chapman, MS
Courtnay Londo, MA
Style and Copy Editor
Marian Deegan, JD
Web Edition Managers
Arkady Shakhnovich
Jermaine Royes
Contributing Writer
Laurel H. Wood, MPA
Technical Reviewer
Robin VanOss
About IZ Express
Immunize.org welcomes redistribution of this issue of IZ Express or selected articles.
When you do so, please add a note that Immunize.org is the source of the material and provide a link to this issue ([link removed]) .
IZ Express is supported in part by Grant No. 1NH23IP922654 from the National Center for Immunization and Respiratory Diseases, CDC. Its contents are solely the responsibility of Immunize.org and do not necessarily represent the official views of CDC.
IZ Express Disclaimer ([link removed])
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