Before midnight tomorrow, you have an extraordinary opportunity to quadruple your impact.

Dear John, The clock is winding down on 2021, but you still have an amazing opportunity to end it on a positive note. Until tomorrow, you have the power to fight back FOUR times as hard to help end Alzheimer's. You can help make 2022 brighter for the millions of people living with Alzheimer's disease by making a special, year-end gift before December 31, during our $100,000 Year-End 4X Match Challenge. When you make a gift today, it can go FOUR TIMES as far to enhance care and support for the more than 6 million Americans living with Alzheimer's, while accelerating critical research around the globe. That can mean more care, support and research — all thanks to our match donor and our best and most generous leaders pitching in. Please give now. There's a very short amount of time left to quadruple the impact of your support — in any amount up to a total of $100,000 — thanks to matching funds provided by a generous donor who wishes to remain anonymous. Their matching gift will support the Tau Pipeline Enabling Program (T-PEP), a funding initiative to accelerate drug development breakthroughs that could help mitigate the toxic effects of tau protein "tangles" in the brain. When you give today, you'll be helping us reach our $100,000 goal. But as I'm sure you'd agree, the goal that matters most is the eradication of Alzheimer's. Until we do that, none of us are safe from this devastating disease. Please make your generous year-end gift, which may be tax deductible, knowing: Your gift of $16 can become $32 $64 until midnight tomorrow. Your gift of $30 can become $60 $120. And your very generous year-end donation of $50 can become $100 $200. But please hurry; the clock is ticking. And when we say the clock is ticking, we don't just mean until December 31. By 2025, the number of people age 65 and older with Alzheimer's dementia is projected to reach 7.2 million — a 16% increase from the 6.2 million of that age affected in 2021. This really is the fight for our lives. I'm hoping you'll please do your part to help advance our mission to lead the way to end Alzheimer's and all other dementia — by accelerating global research, driving risk reduction and early detection, and maximizing quality care and support. John, not everyone knows the threat that Alzheimer's presents to each and every one of us. Right now, one in three seniors dies with Alzheimer's. But I believe you're someone who truly understands this threat and who realizes the importance of investing now to achieve a healthier and more hopeful future for all. And there's no better time than now to show your support, during our $100,000 Year-End 4X Match Challenge, when your one gift can go four times further in the fight against this destructive disease. I want you, and all of us, to be able to look to the future with hope. We'll always have challenges ahead. But if we can eliminate Alzheimer's together, just think how much brighter, and how much better, the future will be. More time with the people we care about. More holiday celebrations with the people we love most. That's what we're fighting for. Please join the fight by making your first gift now. Thank you. Sincerely, Donna McCullough Chief Mission and Field Operations Officer P.S. Happy New Year. Please make your gift that can have 4X the impact on Alzheimer's care, support, and research. Until December 31, your generosity may also be tax-deductible for 2021. I hope you know how much your support is needed and appreciated. Thank you again.

Your donation will strengthen our efforts to advance Alzheimer's care, support and research. From face-to-face support to online education programs and promising global research initiatives, your gift makes a difference in the lives of all those affected by Alzheimer's and other dementias in your community and across the world. Thank you for your continued support. Alzheimer's Association Home Office, 225 N. Michigan Ave., Fl. 17, Chicago, IL 60601 © 2021 Alzheimer's Association. All rights reserved. 800.272.3900 | alz.org® | Donate Please add [email protected] to your address book to ensure you receive all future emails.   Having trouble reading this email? View it in your browser   View your email preferences or unsubscribe.