Our $200,000 Holiday Match Challenge starts with you — TODAY.

Dear John, For those of us united in the fight against Alzheimer's disease, the term "season of giving" takes on a whole new meaning. People living with Alzheimer's may feel a sense of loss during the holidays because of the changes they've experienced — and caregivers may feel overwhelmed by maintaining traditions while providing care and keeping their loved ones safe. That's why your support is needed more than ever at this time of year. Today, I'm honored to share with you that a generous donor who wishes to remain anonymous has given us a fabulous gift for this holiday season by pledging to match all gifts received, up to $200,000 — if we raise the same amount by December 31. Our match donor's gift will support the Tau Pipeline Enabling Program (T-PEP), a funding initiative to accelerate drug development breakthroughs that could help mitigate the toxic effects of tau protein "tangles" in the brain. Because tau tangles are implicated in a number of neurodegenerative disorders, the research made possible by T-PEP could potentially benefit individuals living with Alzheimer's, Parkinson's disease, frontotemporal dementia and more. When you make a gift today, it can go twice as far to enhance care and support for the more than 6 million Americans living with Alzheimer's, while accelerating critical research around the globe. John, this is an ideal time to make your first gift to the Alzheimer's Association — because thanks to this incredible $200,000 Holiday Match Challenge, you can double your impact on our mission to lead the way to end Alzheimer's and all other dementia — by accelerating global research, driving risk reduction and early detection, and maximizing quality care and support. The holidays are often filled with sharing, laughter and traditions. But for families affected by Alzheimer's, this "most wonderful time" can bring stress and sadness. We're here to help through resources available at alz.org, so that caregivers and other loved ones of people living with Alzheimer's can find helpful tips on getting through the holidays, such as how to have conversations with family members in advance to manage expectations regarding the size and type of holiday celebration. Our free 24/7 Helpline (800.272.3900) is also available to offer support and resources, day or night. By making your first gift as part of our $200,000 Holiday Match Challenge today, you'll help ensure we can provide high-quality care and support to everyone who needs us this holiday season and beyond, while also accelerating the most promising dementia research worldwide. Your gift can go twice as far in the fight to end Alzheimer's. Thank you for your compassion and your generous support today, which will help ensure no one will have to face Alzheimer's alone during the holidays — or at any other time — and ultimately, that no one has to face the disease at all. With gratitude, Donna McCullough Chief Mission and Field Operations Officer P.S. This $200,000 Holiday Match Challenge is an amazing gift to our community — but it won't be around long. Donate now, before this match opportunity expires, and you can double your impact on our important work.

Your donation will strengthen our efforts to advance Alzheimer's care, support and research. From face-to-face support to online education programs and promising global research initiatives, your gift makes a difference in the lives of all those affected by Alzheimer's and other dementias in your community and across the world. Thank you for your continued support. Alzheimer's Association Home Office, 225 N. Michigan Ave., Fl. 17, Chicago, IL 60601 © 2021 Alzheimer's Association. All rights reserved. 800.272.3900 | alz.org® | Donate Please add [email protected] to your address book to ensure you receive all future emails.   Having trouble reading this email? View it in your browser   View your email preferences or unsubscribe.