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Issue 1,563: April 28, 2021
Top Stories
* CDC and FDA adopt ACIP recommendation to lift pause on Janssen COVID-19 Vaccine (Johnson & Johnson); CDC updates clinical guidance
* “Postvaccination SARS-CoV-2 Infections among Skilled Nursing Facility Residents and Staff Members—Chicago, Illinois, December 2020–March 2021” published in MMWR
* “COVID-19 Outbreak Associated with a SARS-CoV-2 R.1 Lineage Variant in a Skilled Nursing Facility after Vaccination Program—Kentucky, March 2021” published in MMWR
* Institute for Safe Medication Practices publishes Medication Safety Alert outlining frequently reported COVID-19 vaccination errors
* New! Order IAC’s “I Got My COVID-19 Vaccine” buttons and stickers
* 60 U.S. hospitals team up to promote COVID-19 vaccination in “Get the Vaccine to Save Lives” campaign
* It’s National Infant Immunization Week! Use CDC's 2021 digital media toolkit to spread the word.
* The Vaccine Makers Project of the Vaccine Education Center at CHOP invites essays from students in grades 6 through 12 for 2021 Dr. Maurice Hilleman essay contest
* Voices for Vaccines releases new podcast with Chelsea Clinton to talk about her work on global health and immunization issues
* Ready to ship! Order IAC’s laminated versions of CDC’s 2021 immunization schedules today!
* IAC Spotlight! IAC's "Mandates and Exemptions" gateway page compiles information about state mandates on immunization and vaccine-preventable diseases
* IAC experts called on by news media
* Not-to-miss immunization articles in the news
Featured Resources
* In IAC’s “Video of the Week,” a wise grandmother convinces her family to get vaccinated against COVID-19
* Vaccinated against COVID-19? Encourage friends to follow your lead by adding IAC’s “I Got My COVID-19 Vaccine” Facebook profile photo frame!
* IAC's MenB Vaccination Honor Roll adds three new colleges that protect their students
* IAC's website Mass-Vaccination-Resources.org can help you excel at mass vaccination clinics
* Use IAC's expanded "Repository of Resources for Maintaining Immunization during the COVID-19 Pandemic" for catch-up initiatives
Journal Articles and Newsletters
* CHOP's Vaccine Education Center publishes April issue of Vaccine Update newsletter
* “Effectiveness of Influenza Vaccination in Preventing Hospitalisation Due to Influenza in Children: A Systematic Review and Meta-Analysis” published in Clinical Infectious Diseases
* “Preliminary Findings of mRNA COVID-19 Vaccine Safety in Pregnant Persons” published in New England Journal of Medicine
Education and Training
* CDC offers webinar archive for clinicians titled “Johnson & Johnson/Janssen COVID-19 Vaccine and Thrombosis with Thrombocytopenia Syndrome (TTS): Update for Clinicians”
* National Academies of Sciences, Engineering, and Medicine host “COVID-19 Vaccines: Building Confidence & Explaining Efficacy” webinar on May 4 at 3:00 p.m. (ET)
* Indiana Immunization Coalition hosts “COVID-19 Vaccines: Considerations in Practice” webinar featuring Dr. Samina Bhumbra on May 20 at 3:00 p.m. (ET); CE available
Immunization PSAs from the Archive
* In this somber PSA from 1999 by the Pennsylvania Department of Health, vaccine-preventable diseases are contrasted with extinct animals
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Top Stories
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CDC and FDA adopt ACIP recommendation to lift pause on Janssen COVID-19 Vaccine (Johnson & Johnson); CDC updates clinical guidance
The Advisory Committee on Immunization Practices (ACIP) ([link removed]) met on April 23 ([link removed] ) to review information on the safety of Janssen COVID-19 Vaccine (Johnson & Johnson). Following this review, the Committee voted to recommend lifting the 10-day pause on administration of the Janssen vaccine. Less than 2 hours later, CDC and FDA adopted the recommendation.
As reported in IAC Express #1,561 ([link removed] ), the vaccination pause was called by FDA and CDC on April 13 due to reports of six women who developed a rare and severe type of blood clot (cerebral venous sinus thrombosis [CVST]) occurring in combination with low levels of platelets (thrombocytopenia) after receiving the Janssen vaccine. At its April 14 meeting, ACIP members requested the pause be extended while additional safety data was collected and analyzed.
At the April 23 review, CDC reported on a total of 15 confirmed cases (including the previously reported 6 cases) of thrombosis with thrombocytopenia syndrome (TTS) diagnosed typically 1–2 weeks after vaccination among the 7 million individuals vaccinated with Janssen vaccine in the U.S before the pause. All 15 patients were women: thirteen were age 18–49 years and 2 were age 50–64 years. The incidence of TTS among Janssen vaccine recipients was 7 cases per million vaccinated women age 18–49 years and less than 1 per million vaccinated women age 50 years and older. No apparent links with typical risk factors for thrombosis (e.g., obesity, oral contraceptive use) were observed.
ACIP also evaluated the benefits of the Janssen vaccine, including its high level of protection against circulating COVID-19 variants and the logistical advantages of a single-dose vaccine stored at routine refrigerated temperatures. In particular, ACIP reviewed models indicating that, in the context of current rates of COVID-19 infection in the U.S., continued use of the Janssen vaccine could result in 26–45 cases of TTS in people age 18 and older, while preventing up to 1,400 deaths and 3,500 ICU admissions from COVID-19.
Following extensive discussion, ACIP voted to reaffirm its original recommendation: “The Janssen COVID-19 vaccine is recommended for persons 18 years of age and older in the U.S. population under the FDA’s Emergency Use Authorization [EUA].” The vote was ten in favor, four opposed, and one abstention. A minority view held that the ACIP recommendation should specifically include the need to inform women under 50 years of age about the risk of TTS and the option to choose a different COVID-19 vaccine without that risk. The majority believed inclusion of information in the EUA Fact Sheets provided to vaccination providers ([link removed]) and recipients and caregivers ([link removed]), plus CDC clinical guidance and patient education materials, would be sufficient.
ACIP members emphasized the importance of education for medical providers and the general public about TTS in association with Janssen COVID-19 Vaccine. On Tuesday, April 27, CDC issued a MMWR titled Updated Recommendations from the Advisory Committee on Immunization Practices for Use of the Janssen (Johnson & Johnson) COVID-19 Vaccine After Reports of Thrombosis with Thrombocytopenia Syndrome Among Vaccine Recipients—United States, April 2021 ([link removed]), and updated its webpage on Interim Clinical Considerations for Use of COVID-19 Vaccines Currently Authorized in the U.S. ([link removed]), including a summary document ([link removed]). On the same day, CDC held a Clinician Outreach and Communication (COCA) clinician update ([link removed])
teleconference. Appropriate materials also have been updated on the CDC’s Janssen COVID-19 Vaccine (Johnson & Johnson) product page ([link removed]).
TTS has not been reported following administration of more than 190 million doses of the mRNA-based Pfizer-BioNTech and Moderna vaccines. The underlying cause of TTS syndrome remains under investigation, having been associated with both Oxford/AstraZeneca and Janssen adenovirus-vector vaccines. Healthcare providers (HCPs) are urged to maintain a high index of suspicion for TTS symptoms, including severe headache, backache, new neurologic symptoms, severe abdominal pain, shortness of breath, leg swelling, petechiae (tiny red spots on the skin), or new and easy bruising, with typical onset 1–2 weeks post-vaccination. TTS symptoms appear later than the common vaccine side effects (e.g., headache) that typically occur 1–3 days after vaccination and resolve spontaneously. Suspected TTS should not be treated with heparin. The American Society of Hematology has published considerations relevant to the diagnosis and treatment of TTS
([link removed]) following the Janssen COVID-19 Vaccine. Possible cases of TTS should be reported immediately to the Vaccine Adverse Events Reporting System ([link removed]).
Related Links
* Joint CDC and FDA Statement: FDA and CDC Lift Recommended Pause on Johnson & Johnson (Janssen) COVID-19 Vaccine Use following Thorough Safety Review ([link removed])
* Janssen COVID-19 Vaccine EUA Fact Sheet for Healthcare Providers ([link removed])(updated April 23, 2021)
* Janssen COVID-19 Vaccine EUA Fact Sheet for Potential Recipients and Caregivers ([link removed])(updated April 23, 2021)
* MMWR: Updated Recommendations from the Advisory Committee on Immunization Practices for Use of the Janssen (Johnson & Johnson) COVID-19 Vaccine After Reports of Thrombosis with Thrombocytopenia Syndrome Among Vaccine Recipients—United States, April 2021 ([link removed])
* Interim Clinical Considerations for Use of COVID-19 Vaccines Currently Authorized in the U.S. ([link removed])
* ACIP Presentation Slides ([link removed] ) : April 23, 2021 meeting gateway page
* CDC COCA Update for Clinicians: Johnson & Johnson/Janssen COVID-19 Vaccine and Thrombosis with Thrombocytopenia Syndrome (TTS) ([link removed])
* American Society of Hematology: Vaccine-Induced Immune Thrombotic Thrombocytopenia: Key Takeaways and FAQs ([link removed])
* American Society of Hematology and CDC Joint Webinar – Diagnosis and Management of Suspected Vaccine-Induced Immune Thrombotic Cytopenia (VITT) following Johnson & Johnson (Janssen) COVID-19 Vaccination ([link removed]) (4/20/21)
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“Postvaccination SARS-CoV-2 Infections among Skilled Nursing Facility Residents and Staff Members—Chicago, Illinois, December 2020–March 2021” published in MMWR
CDC published Postvaccination SARS-CoV-2 Infections among Skilled Nursing Facility Residents and Staff Members—Chicago, Illinois, December 2020–March 2021 ([link removed]) in MMWR on April 21. Portions of the summary appear below.
...Twenty-two possible breakthrough SARS-CoV-2 infections occurred among fully vaccinated persons ≥14 days after their second dose of COVID-19 vaccine. Two thirds of persons were asymptomatic. A minority of persons with breakthrough infection experienced mild to moderate COVID-19–like symptoms; two COVID-19–related hospitalizations and one death occurred. No facility-associated secondary transmission was identified.…
The results in this report highlight the importance of COVID-19 vaccination in high-risk congregate settings such as SNFs; most fully vaccinated persons were not infected, did not have COVID-19–like symptoms, and did not have severe illness.…
[Skilled nursing facilities] (SNFs) should prioritize vaccination and follow recommended COVID-19 infection prevention and control practices, including following work restrictions, isolation, quarantine, testing of residents and staff members, and use of personal protective equipment.
Access the MMWR article in HTML format ([link removed]) or in PDF format ([link removed]).
Related Link
* MMWR's gateway page ([link removed]) provides access to MMWR Weekly, MMWR Recommendations and Reports, MMWR Surveillance Summaries, and MMWR Supplements
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“COVID-19 Outbreak Associated with a SARS-CoV-2 R.1 Lineage Variant in a Skilled Nursing Facility after Vaccination Program—Kentucky, March 2021” published in MMWR
CDC published COVID-19 Outbreak Associated with a SARS-CoV-2 R.1 Lineage Variant in a Skilled Nursing Facility after Vaccination Program—Kentucky, March 2021 ([link removed]) in MMWR on April 21. Despite exposure to a variant, vaccinated skilled nursing facility residents and workers were much less likely to have symptomatic COVID-19 infection. Portions of the summary appear below.
...In a COVID-19 outbreak at a Kentucky [skilled nursing facility] SNF involving a newly introduced variant to the region, unvaccinated residents and health care personnel (HCP) had 3.0 and 4.1 times the risk of infection as did vaccinated residents and HCP. Vaccine was 86.5% protective against symptomatic illness among residents and 87.1% protective among HCP.
Vaccination of SNF residents and HCP is essential to reduce the risk for symptomatic COVID-19, as is continued focus on infection prevention and control practices.
Access the MMWR article in HTML format ([link removed]) or in PDF format ([link removed]).
Related Link
* MMWR's gateway page ([link removed]) provides access to MMWR Weekly, MMWR Recommendations and Reports, MMWR Surveillance Summaries, and MMWR Supplements
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Institute for Safe Medication Practices publishes Medication Safety Alert outlining frequently reported COVID-19 vaccination errors
The Institute for Safe Medication Practices has published a report titled, Any New Process Poses a Risk for Errors: Learning from 4 Months of COVID-19 Vaccinations ([link removed]) in the April 22 issue of Medication Safety Alert ([link removed]).
ISMP categorizes more than 160 error reports as follows:
* General errors: Wrong dose (20% of reports), wrong age (17%), wrong technique (8%), wasted vaccine (5%), incorrect storage and handling (4%), contraindicated coadministration (2%)
* Errors specific to mRNA vaccines: Mixed vaccine series (11%), wrong time interval (9%)
* Dilution errors specific to Pfizer-BioNTech vaccine: Wrong volume of diluent (11%), no diluent (3%), wrong diluent (3%)
* Errors specific to Janssen (J&J) vaccine: Two-dose record card shipped with single-dose vaccine (1%)
[link removed]
Graphic appearing in referenced Institute for Safe Medication Practice report.
ISMP offers specific safe-practice recommendations in these categories:
* Staff competency verification
* Patient scheduling and check-in processes
* Product preparation
* Dose administration
* Response to error recognition
Access the full article and use their safe-practice recommendations for staff training: Any New Process Poses a Risk for Errors: Learning from 4 Months of COVID-19 Vaccinations ([link removed]).
Related Links
* Institute for Safe Medication Practices ([link removed]) (ISMP)
* ISMP Vaccine Error Reporting Program ([link removed]) (VERP)
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New! Order IAC’s “I Got My COVID-19 Vaccine” buttons and stickers
IAC now offers “I Got My COVID-19 Vaccine ([link removed]) ” buttons and stickers for purchase. Place them on lab coats, uniforms, jackets, lanyards, ID badges, or backpacks to show your confidence in COVID-19 vaccination.
Buttons: Wear them to reassure your patients and remind those around you to protect themselves from COVID-19.
* Description: Bright yellow, black and blue text, metal pin that clasps on the back
* Packaging: Bag of 25 buttons
* Dimension: 1.5" across
* To order: See Shop IAC: COVID-19 Vaccine Buttons and Stickers ([link removed]) for quantity and pricing options
Stickers: Give away to COVID-19 vaccine recipients or vaccinated clinic staff!
* Description: Bright yellow stickers on a roll with an easy-peel-off back and perforations between stickers to make them easy to tear off and share
* Packaging: Roll of 200 stickers
* Dimension: 1.5" across
* To order: See Shop IAC: COVID-19 Vaccine Buttons and Stickers ([link removed]) for quantity and pricing options
Please note: Through a separate program supported by CDC, public health departments and selected CDC nonprofit Vaccinate with Confidence ([link removed]) campaign partners have been notified about how to receive limited supplies of these items at no cost.
For questions, call 651-647-9009 or email
[email protected].
Related Links
* Shop IAC: COVID-19 Vaccine Buttons and Stickers ([link removed])
* Shop IAC ([link removed]) gateway page: All the buttons, stickers, laminated schedules, record cards, and other products offered by IAC
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60 U.S. hospitals team up to promote COVID-19 vaccination in “Get the Vaccine to Save Lives” campaign
A campaign led by Cleveland Clinic and Mayo Clinic, with support from 60 top hospitals and health care institutions, will encourage adults to get vaccinated against COVID-19. The Get the Vaccine to Save Lives ([link removed]) campaign is designed to reassure the public that vaccines are safe, effective, and necessary to achieve herd immunity and return to normal activities. A paragraph from the press release appears below.
The campaign hopes to reach adults who are hesitant to receive a vaccine, including racial and minority ethnic groups and people living in rural communities. According to a Kaiser Family Foundation survey published March 30, 17% of the public say they will take a wait-and-see approach before getting it themselves, and another 20% say they will never get a vaccine or will only get it if required to do so for work, school or other activities. This leaves a significant portion of the population at risk of going unvaccinated.
Related Links
* Cleveland Clinic Press Release: Leading U.S. Hospitals Team Up to Promote COVID-19 Vaccination ([link removed]) (4/20/21)
* "Get the Vaccine to Save Lives" campaign website: [link removed]
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It’s National Infant Immunization Week! Use CDC's 2021 digital media toolkit to spread the word.
National Infant Immunization Week ([link removed]) (NIIW), April 24–May 1, highlights the importance of protecting infants from vaccine-preventable diseases and celebrates the achievements of immunization partners. This year, because of the pandemic, it’s critical to ensure that families stay on track for their children’s routine checkups.
Since 1994, hundreds of U.S. communities have joined together during NIIW to celebrate the critical role vaccination plays in protecting our children, communities, and public health. Giving babies and toddlers the recommended vaccinations by age two is the best way to protect them from 14 serious childhood diseases.
Save time by using CDC's 2021 NIIW Digital Media Toolkit ([link removed]) to plan and implement your organization's NIIW activities. The toolkit includes updated logos, sample social media content, social graphics, and key messages. Please share them, using the hashtag #ivax2protect.
Related Links
* CDC's National Infant Immunization Week ([link removed]) gateway page
* CDC's 2021 NIIW Digital Media Toolkit ([link removed]) gateway page
* IAC's Parent Handouts ([link removed]) gateway page
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The Vaccine Makers Project of the Vaccine Education Center at CHOP invites essays from students in grades 6 through 12 for 2021 Dr. Maurice Hilleman essay contest
The Vaccine Makers Project ([link removed]), the classroom-based program of the Vaccine Education Center (VEC) at Children's Hospital of Philadelphia, is currently inviting essays for the 2021 Maurice R. Hilleman Essay Contest. Students in grades 6 through 12 are encouraged to learn about Dr. Hilleman’s life and accomplishments and submit a 500- to 600-word essay that answers the question, “How do Dr. Hilleman’s accomplishments demonstrate the importance of creativity in science?” Entries will be accepted through June 4, 2021.
* Learn more about Dr. Maurice Hilleman ([link removed]), considered by many to be "the father of modern vaccines"
* View the printable flyer ([link removed]) for more details about the contest and prizes
Details and entry form are available at HillemanFilm.com/contest ([link removed]). Three winners will each receive $1,000, a certificate, a VEC prize bag, and recognition at a virtual award event this fall. Please feel free to share this information with eligible students or with teachers who might be interested in sharing with their students.
Related Links
* Vaccine Makers Project ([link removed]) website
* VEC's Hilleman Film ([link removed]) website
* IAC Express #1,498: Teaching Young People about Vaccines: IAC Compiles Reliable Resources for Instructing High School Students on Vaccines and How They Work ([link removed])
* IAC Express #1,496: Teaching Young People about Vaccines: IAC Compiles Reliable Resources for Instructing Middle School–Aged Children on Vaccines and How They Work ([link removed])
* IAC Express #1,495: Teaching Young People about Vaccines: IAC Compiles Reliable Resources for Instructing Elementary School-Aged Children on Vaccines and How They Work ([link removed])
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Voices for Vaccines releases new podcast with Chelsea Clinton to talk about her work on global health and immunization issues
Voices for Vaccines (VFV) has posted a new entry in its Vax Talk podcast series: It’s Chelsea Clinton! ([link removed]). A description from their web page appears below.
Chelsea Clinton comes from a background of public service, so why is she working so hard on global health right now? And why is she willing to take a stand for vaccines?
* Visit VFV website podcast page ([link removed])
* Subscribe to Vax Talk via Apple Podcasts ([link removed]) or PodBean ([link removed])
Voices for Vaccines is a national organization of parents and others who are dedicated to raising the level of the voices of immunization supporters. VFV invites everyone who values vaccines to become a member, use VFV tools in their own community, and sign up for VFV’s free newsletter ([link removed]). Please spread the word to your friends and colleagues to join VFV!
Related Links
* Voices for Vaccines ([link removed]) website
* Voices for Vaccines Tools ([link removed]) gateway page
* Join Voices for Vaccines ([link removed]) and receive weekly email updates
* Follow Voices for Vaccines on Facebook ([link removed])
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Ready to ship! Order IAC’s laminated versions of CDC’s 2021 immunization schedules today!
IAC's laminated versions of the 2021 U.S. child/adolescent immunization schedule ([link removed]) and the 2021 U.S. adult immunization schedule ([link removed]) are available for order.
These schedules are ideal for use in any busy healthcare setting where vaccinations are given. Their tough coating can be wiped down, and they’re durable enough to stand up to a year's worth of use.
The child/adolescent schedule is eight pages (i.e., four double-sided pages) and the adult schedule is six pages (i.e., three double-sided pages), but both schedules fold down to a convenient 8.5" x 11" size.
With color coding for easy reading, our laminated schedules replicate the original CDC formatting, including the essential tables and notes.
PRICING
1–4 copies: $7.50 each
5–19 copies: $5.50 each
20–99 copies: $4.50 each
100–499 copies: $4.00 each
500–999 copies: $3.50 each
For quotes on customizing or placing orders of 1,000 copies or more, call 651-647-9009 or email
[email protected].
Visit the Shop IAC: Laminated Schedules ([link removed]) web page for more information on the schedules, to view images of all the pages, and to download the order form today!
Related Links
* IAC’s laminated Child/Adolescent Immunization Schedules (0–18 years) ([link removed]) web page
* IAC’s laminated Adult Immunization Schedules (19 and older) ([link removed]) web page
* IAC’s Shop IAC ([link removed]) section on immunize.org
* CDC’s Immunization Schedules for 2021 ([link removed])
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IAC Spotlight! IAC's "Mandates and Exemptions" gateway page compiles information about state mandates on immunization and vaccine-preventable diseases
IAC's Mandates and Exemptions ([link removed]) gateway page contains links to state-specific situations in three ways, accessed from the upper left corner:
* Vaccine-Specific Requirements ([link removed]) leads to “State Laws and Mandates by Vaccine,” which links to 15 subordinate pages with details by age and vaccine type
* Exemptions by State ([link removed]), linking to discussions of the rationale for requirements and policy statements from medical organizations endorsing these requirements and describing the risks of personal belief and non-medical exemptions
* State Immunization Websites ([link removed]), linking to websites for 50 states and the District of Columbia.
You can locate this content via State Laws and Mandates ([link removed]) within the Favorites tab in the blue bar across the top of any immunize.org web page.
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IAC EXPERTS CALLED ON BY NEWS MEDIA
With vaccines in the news so much lately, journalists have sought out IAC experts to communicate the intricacies of running a quality vaccination program. Our insights have helped explain vaccines to the public and policy makers. We want to help them understand the complex work vaccinators do. We've reached mass markets and local stations, across the U.S. and overseas, via print, radio, television, blogs, and more. Here is a selection of our recent citations:
* Washington Post: The Johnson & Johnson Pause Hit Just as the Country Needs to Reach Out to More Americans ([link removed]) (4/26/21)
* Washington Post: These Are the Pro-vaccine Messages People Want to Hear ([link removed]) (4/22/21)
Related Link
* IAC in the News ([link removed]) gateway page
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Not-to-miss immunization articles in the news
These recent articles convey the potential risks of vaccine-preventable diseases and the importance of vaccination.
* New York Times: What Do You Do When the Kids Are Still Unvaccinated? ([link removed]) (4/22/21)
* New York Times: The Flu Vanished during COVID. What Will Its Return Look Like? ([link removed]) (4/22/21)
* ABC: Biden Announces 200 Million Vaccine Dose Goal Being Met Early ([link removed]) (4/21/21)
* Science: Here’s How Scientists Are Designing Vaccines That Can Ditch the Fridge ([link removed]) (4/21/21)
* AP News: Bill Ending Religious Vaccine Exemption Now Heads to Senate ([link removed]) (4/20/21)
* Smithsonian Magazine: Experts Answer Eight Key Questions about COVID-19 Vaccine Reactions ([link removed]) (4/20/21)
* USA Today: Is Herd Immunity to COVID-19 Possible? Experts Increasingly Say No. ([link removed]) (4/19/21)
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Featured Resources
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IN IAC’S “VIDEO OF THE WEEK,” A WISE GRANDMOTHER CONVINCES HER FAMILY TO GET VACCINATED AGAINST COVID-19
In this animated video written by Maya Adam, MD, of Stanford Medicine ([link removed]), a wise grandmother convinces her family, absorbed in their digital devices, to get vaccinated. Although her family members are reluctant at first, she gets a COVID-19 shot and then finds a way to explain the power of vaccines against many diseases.
Visit the whole collection at the VOTW archive ([link removed]).
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VACCINATED AGAINST COVID-19? ENCOURAGE FRIENDS TO FOLLOW YOUR LEAD BY ADDING IAC’S “I GOT MY COVID-19 VACCINE” FACEBOOK PROFILE PHOTO FRAME!
Share your excitement about COVID-19 vaccination and inspire your friends! When you have received your COVID-19 vaccine, add IAC's new "I Got My COVID-19 Vaccine" Facebook photo frame to liven up your profile picture!
You can obtain the frame in two ways:
* Click your profile picture, select “update picture,” and then select “add a frame.” Search for #igotmycovid19vaccine and select it.
* Accept the frame by clicking this link: www.facebook.com/profilepicframes/? selected_overlay_id=2361854253958052
Together we can end the COVID-19 pandemic!
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IAC's MenB Vaccination Honor Roll adds three new colleges that protect their students
The Immunization Action Coalition (IAC) is pleased to announce that three new post-secondary institutions have been enrolled into its MenB Vaccination Honor Roll ([link removed]) for requiring or recommending meningococcal serogroup B vaccine for students.
The newly added institutions are listed below. Clicking on the institutions' names brings you to the place on the school's website that details their vaccine requirements and recommendations.
* St. John’s College ([link removed]), Annapolis, MD – recommended
* St. John’s College ([link removed]), Santa Fe, NM – recommended
* Dominican University of California ([link removed]), San Rafael, CA – recommended
Currently, there are 270 honorees, with 40 colleges and universities requiring MenB vaccination for their students and 230 recommending it.
IAC launched the MenB Vaccination Honor Roll ([link removed]) to recognize exemplary institutions that have taken the lead in establishing policies requiring or recommending meningococcal serogroup B (MenB) vaccination to protect their students.
Please help us to grow the honor roll by notifying us of colleges or universities that require or recommend MenB vaccination for their students. Colleges and universities may apply for the honor roll ([link removed]) or you can alert us at
[email protected].
Please visit the MenB Vaccination Honor Roll ([link removed]) web page to find resources such as news stories about meningitis B outbreaks, personal stories from families affected by meningitis B, journal articles, and links to organizations that work to prevent meningitis.
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IAC'S WEBSITE MASS-VACCINATION-RESOURCES.ORG CAN HELP YOU EXCEL AT MASS VACCINATION CLINICS
The Immunization Action Coalition’s website www.Mass-Vaccination-Resources.org ([link removed]) assists you in finding ideas for developing your own mass vaccination clinics. Mass vaccination efforts will continue to be useful for expediting COVID-19 vaccination now, as well as other vaccinations in the future.
Many of the documents were written in the pre-pandemic era and will need modification to ensure that additional protections, such as social distancing and personal protective equipment, help safeguard against COVID-19 transmission.
In addition, IAC's archived, full-length webinar (1 h. 46 min.) highlighting best practices and offering practical information for conducting a successful mass vaccination clinic, Mass Vaccination Clinics: Challenges and Best Practices ([link removed]), can be viewed on www.Mass-Vaccination-Resources.org.
If you have a resource to suggest for the website, please send a message to
[email protected].
The webinar and the new website are supported by a medical education grant from Seqirus.
Related Links
* IAC's Mass Vaccination Resources ([link removed]) website
* CDC’s Guidance for Planning Vaccination Clinics Held at Satellite, Temporary, or Off-Site Locations ([link removed])
* IAC's Mass Vaccination Clinics: Challenges and Best Practices ([link removed]) archived webinar
* Becker’s Hospital Review: Influenza Vaccination Is More Important than Ever: To Help, Immunization Action Coalition Launches New Mass Vaccination Resources ([link removed])
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USE IAC'S EXPANDED "REPOSITORY OF RESOURCES FOR MAINTAINING IMMUNIZATION DURING THE COVID-19 PANDEMIC" FOR CATCH-UP INITIATIVES
IAC now offers 287 items in its Repository of Resources for Maintaining Immunization during the COVID-19 Pandemic ([link removed]) gateway page to assist in maintaining routine immunization rates during the COVID-19 pandemic. Located on the website of the National Network of Immunization Coalitions ([link removed]), a project of IAC, this repository includes links to both national and state-level policies and guidance; advocacy materials, including talking points, webinars, press releases, articles, and social media posts; and telehealth resources.
If you have a resource to suggest for the repository, please send a message to
[email protected].
Related Link
* National Network of Immunization Coalitions ([link removed]) website
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Journal Articles and Newsletters
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CHOP's Vaccine Education Center publishes April issue of Vaccine Update newsletter
The Vaccine Education Center (VEC) ([link removed]) at Children's Hospital of Philadelphia (CHOP) publishes a monthly immunization-focused newsletter titled Vaccine Update. The April issue ([link removed]) includes the following articles:
* COVID-19: The Vaccine versus the Variants ([link removed]) by Charlotte A. Moser, BS, and Paul A. Offit, MD
* Name the Logical Fallacy: COVID-19 Edition ([link removed]) by Paul A. Offit, MD
Additional resources, including information booklets for patients, are available in the full newsletter ([link removed]).
Access the sign-up form ([link removed]) to subscribe to Vaccine Update.
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“Effectiveness of Influenza Vaccination in Preventing Hospitalisation Due to Influenza in Children: A Systematic Review and Meta-Analysis” published in Clinical Infectious Diseases
In the March 27 issue, Clinical Infectious Diseases published Effectiveness of Influenza Vaccination in Preventing Hospitalisation Due to Influenza in Children: A Systematic Review and Meta-Analysis ([link removed]). A portion of the abstract appears below.
This systematic review assesses the literature for estimates of influenza vaccine effectiveness (IVE) against laboratory-confirmed influenza-associated hospitalisation in children....
...A random-effects meta-analysis of 37 studies that used a test-negative design gave a pooled seasonal IVE against hospitalisation of 53.3% (47.2-58.8) for any influenza. IVE was higher against influenza A/H1N1pdm09 (68.7%, 56.9-77.2) and lowest against influenza A/H3N2 (35.8%, 23.4-46.3). Estimates by vaccine type ranged from 44.3% (30.1-55.7) for LAIV to 68.9% (53.6-79.2) for inactivated vaccines. IVE estimates were higher in seasons when the circulating influenza strains were antigenically matched to vaccine strains (59.3%, 48.3-68.0).
Influenza vaccination gives moderate overall protection against influenza-associated hospitalisation in children supporting annual vaccination. IVE varies by influenza subtype and vaccine type.
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"Preliminary Findings of mRNA COVID-19 Vaccine Safety in Pregnant Persons" published in New England Journal of Medicine
In the April 21 issue, the New England Journal of Medicine published Preliminary Findings of mRNA COVID-19 Vaccine Safety in Pregnant Persons ([link removed]). Portions of the abstract sections appear below.
Methods
From December 14, 2020, to February 28, 2021, we used data from the “v-safe after vaccination health checker” surveillance system, the v-safe pregnancy registry, and the Vaccine Adverse Event Reporting System (VAERS) to characterize the initial safety of mRNA Covid-19 vaccines in pregnant persons.
Results
A total of 35,691 v-safe participants 16 to 54 years of age identified as pregnant. Injection-site pain was reported more frequently among pregnant persons than among nonpregnant women, whereas headache, myalgia, chills, and fever were reported less frequently. Among 3958 participants enrolled in the v-safe pregnancy registry, 827 had a completed pregnancy, of which 115 (13.9%) resulted in a pregnancy loss and 712 (86.1%) resulted in a live birth (mostly among participants with vaccination in the third trimester). Adverse neonatal outcomes included preterm birth (in 9.4%) and small size for gestational age (in 3.2%); no neonatal deaths were reported. Although not directly comparable, calculated proportions of adverse pregnancy and neonatal outcomes in persons vaccinated against Covid-19 who had a completed pregnancy were similar to incidences reported in studies involving pregnant women that were conducted before the Covid-19 pandemic. Among 221 pregnancy-related adverse events reported to the VAERS, the most frequently reported event was spontaneous abortion (46 cases).
Conclusions
Preliminary findings did not show obvious safety signals among pregnant persons who received mRNA Covid-19 vaccines. However, more longitudinal follow-up, including follow-up of large numbers of women vaccinated earlier in pregnancy, is necessary to inform maternal, pregnancy, and infant outcomes.
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Education and Training
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CDC OFFERS WEBINAR ARCHIVE FOR CLINICIANS TITLED “JOHNSON & JOHNSON/JANSSEN COVID-19 VACCINE AND THROMBOSIS WITH THROMBOCYTOPENIA SYNDROME (TTS): UPDATE FOR CLINICIANS”
CDC is offering an archive of its Clinical Outreach and Communication Activity (COCA) webinar which originally aired on April 27, 2021. Titled Johnson & Johnson/Janssen COVID-19 Vaccine and Thrombosis with Thrombocytopenia Syndrome (TTS): Update for Clinicians ([link removed]), CDC has provided the following description of this session:
This COCA Call will present the latest evidence on thrombosis with thrombocytopenia syndrome (TTS) after administration of the Johnson & Johnson/Janssen COVID-19 vaccine. Speakers will discuss information on TTS and updated vaccine recommendations.
Access more information about this webinar: Johnson & Johnson/Janssen COVID-19 Vaccine and Thrombosis with Thrombocytopenia Syndrome (TTS): Update for Clinicians ([link removed]).
Related Link
* COCA web section ([link removed])
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NATIONAL ACADEMIES OF SCIENCES, ENGINEERING, AND MEDICINE HOST “COVID-19 VACCINES: BUILDING CONFIDENCE & EXPLAINING EFFICACY” WEBINAR ON MAY 4 AT 3:00 P.M. (ET)
The National Academies of Sciences, Engineering, and Medicine will present a webinar titled COVID-19 Vaccines: Building Confidence & Explaining Efficacy ([link removed]) on May 4 from 3:00–4:00 p.m. (ET). The webinar will cover public engagement and communications strategies public officials can use to promote vaccination, build vaccine confidence, and overcome confusing messages about vaccine efficacy.
Register for the webinar ([link removed]).
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INDIANA IMMUNIZATION COALITION HOSTS “COVID-19 VACCINES: CONSIDERATIONS IN PRACTICE” WEBINAR FEATURING DR. SAMINA BHUMBRA ON MAY 20 AT 3:00 P.M. (ET); CE AVAILABLE
The Indiana Immunization Coalition will host a webinar titled COVID-19 Vaccines: Considerations in Practice ([link removed]) from 3:00–4:00 p.m. (ET) on May 20. This presentation will identify the various COVID-19 vaccine options and present current guidance for providers related to vaccine components, mechanisms of action, and considerations for administration in various age groups. The presenter is Samina Bhumbra, MD. Dr. Bhumbra is an assistant professor of clinical pediatrics at the Indiana University School of Medicine. CME, CNE, and CPE will be offered.
Register for the webinar ([link removed]).
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Immunization PSAs from the Archive
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IN THIS SOMBER PSA FROM 1999 BY THE PENNSYLVANIA DEPARTMENT OF HEALTH, VACCINE-PREVENTABLE DISEASES ARE CONTRASTED WITH EXTINCT ANIMALS
In this 1999 public service announcement (PSA) ([link removed]) from the Pennsylvania Department of Health, vaccine-preventable diseases are contrasted with extinct animals. This PSA is part of a collection curated by vaccine expert William L. Atkinson, MD, MPH.
Previous PSAs featured in “From the Archives” are available when viewing this Vimeo video ([link removed]).
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Video of the Week
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End the Pandemic. Vaccines Work. In this animated video written by Maya Adam, MD, of Stanford Medicine, a wise grandmother convinces her family, absorbed in their digital devices, to get vaccinated. Although her family members are reluctant at first, she gets a COVID-19 shot and then finds a way to explain the power of vaccines against many diseases. [1:19]
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Technically Speaking
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Read Dr. Wexler's column for the Vaccine Education Center's monthly newsletter, Vaccine Update
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Vaccinating Adults: A Step-by-Step Guide
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New! IAC's 142-page book available for free download ([link removed]).
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Calendar of Events
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Conferences, meetings, and training opportunities
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Patient Record Cards
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Record cards for patients --child & teen ([link removed]), adult ([link removed]), and lifetime ([link removed]) -- are printed on durable paper and sized to fit in a wallet when folded
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DVD: Immunization Techniques
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Every practice should have this award winning, "how-to" training video
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Protect Newborns Guidebook
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Comprehensive guide Hepatitis B: What Hospitals Need to Do to Protect Newborns ([link removed])
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Editorial Information
Editor
Deborah L. Wexler, MD (
[email protected])
Associate Editors
John Grabenstein, RPh, PhD (
[email protected])
Sharon Humiston, MD, MPH (
[email protected])
Consulting Editors
Taryn Chapman, MS (
[email protected])
Marian Deegan, JD (
[email protected])
Courtnay Londo, MA (
[email protected])
Technical Editor
Robin VanOss (
[email protected])
About IAC Express
The Immunization Action Coalition welcomes redistribution of this issue of IAC Express or selected articles. When you do so, please add a note that the Immunization Action Coalition is the source of the material and provide a link to this issue ([link removed]).
IAC Express is supported in part by Grant No. 6NH23IP922550 from the National Center for Immunization and Respiratory Diseases, CDC. Its contents are solely the responsibility of IAC and do not necessarily represent the official views of CDC.
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