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BREAST CANCER RESEARCH NEWS: WHAT YOU NEED TO KNOW
November 2020
 

FDA Approves Immunotherapy Keytruda for PD-L1-Positive Triple-Negative Breast Cancer
Last week Keytruda was approved in combination with chemotherapy to treat locally advanced or metastatic triple-negative, PD-L1-positive breast cancer that can’t be removed with surgery. Results from a clinical trial showed that the treatment combination offered better progression-free survival than chemotherapy alone.

 
Breast Cancers Found Between Regular Screening Mammograms Seem More Aggressive
Researchers looked at information from 69,025 women who were part of the national breast cancer screening program in Manitoba, Canada, from January 2004 to June 2010. According to the study, interval cancers were more likely to have aggressive characteristics than breast cancers found by routine screening.
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Study: Older Women With Early-Stage HER2-Positive Breast Cancer May Be Able to Skip Chemotherapy
Researchers wanted to see if treating certain women aged 70 to 80 with Herceptin alone after surgery offered the same benefits as treating them with Herceptin plus chemotherapy because this age group has a higher risk of side effects from chemotherapy.
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Better Survival for Early-Stage HER2-Positive Breast Cancer Linked to Pathologic Complete Response to Targeted Therapy Before Surgery
Women diagnosed with early-stage HER2-positive breast cancer treated with Herceptin and Tykerb before surgery who had a pathologic complete response (pCR) had better survival than women who didn’t have a pCR.
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Early Results Suggest Ibrance Plus Faslodex as First Treatment Improves Outcomes for Metastatic Hormone-Receptor-Positive, HER2-Negative Breast Cancer
The Ibrance and Faslodex treatment combination improved progression-free survival compared to Faslodex alone, according to the FLIPPER study. The early results are encouraging, but more research is needed to see if this improvement translates into better overall survival.
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The Breastcancer.org research news update is sponsored by Lilly Oncology.
 
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