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IZ Express #1,852: New CDC childhood immunization schedule, GSK MenABCWY vaccine, and more
| From | Immunize.org <[email protected]> |
| Subject | IZ Express #1,852: New CDC childhood immunization schedule, GSK MenABCWY vaccine, and more |
| Date | January 14, 2026 11:15 AM |
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Issue 1,852: January 14, 2026
Top Stories
* HHS and CDC release 2026 childhood immunization schedule; what it means today for frontline providers
* “Use of the GSK MenACWY-CRM/MenB-4C Pentavalent Meningococcal Vaccine Among Persons Aged ≥10 Years: Recommendations of the Advisory Committee on Immunization Practices—United States, 2025” published in MMWR
* Respiratory viral activity rises sharply across the country; vaccination reduces risk of severe illness
* Measles: 2025 ends with 2,144 confirmed cases; 2026 begins with three cases in two states
* “Can We Give Influenza Vaccine with Other Vaccines?” See the rationale for simultaneous vaccination in this 3-minute video, part of the Ask the Experts Video Series on YouTube.
* Journalists interview Immunize.org experts
* Vaccines in the news
Immunize.org Website and Clinical Resources
* Spotlight on the website: Publication archives
* Recap: Immunize.org updates “Standing Orders for Administering Meningococcal B Vaccine (MenB) to Adolescents and Adults”
* Recap: Immunize.org updates parent handout, “Top Ten Reasons to Protect Your Child by Vaccinating”
* Recap: Immunize.org updates “Don't Be Guilty of These Preventable Errors in Vaccine Administration!”
* Recap: Immunize.org updates “Questions and Answers” resource on varicella
Featured Resources
* Recap: Immunize.org adds vaccine schedules and searchable database of recommendations published by healthcare professional organizations
* Updated 65+ Flu Defense website offers resources for healthcare professionals serving older adults
* Immunize.org's elegant "Vaccination Saves Lives" blue enamel pins make wonderful workplace recognitions
* Needle anxiety is common at any age. Use Immunize.org’s clinical resources to offer a positive vaccination experience.
* Help Immunize.org reach more vaccinators through your social media networks. Follow us and share our posts on Facebook, Instagram, and LinkedIn!
Notable Publications
* “Updated Evidence for COVID-19, RSV, and Influenza Vaccines for 2025–2026” published in New England Journal of Medicine
Upcoming Events
* Virtual: Register for Immunize.org Website Office Hours. Join a 30-minute discussion about our new Official Guidance: Healthcare Professional Organization Schedules content on February 11 at 4:00 p.m. (ET) or February 12 at 12:00 p.m. (ET). Recorded sessions archived.
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Top Stories
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HHS and CDC release 2026 childhood immunization schedule; what it means today for frontline providers
On January 5, HHS and CDC announced changes to the childhood immunization schedule ([link removed]), following a Presidential directive ([link removed]) to align U.S. recommendations with those of “peer, developed countries.” This resulted in the acting CDC director’s decision to retain, as routinely recommended, the vaccines routinely recommended by other countries selected by HHS for evaluation. Other vaccines on the previous CDC schedule were shifted to categories of recommendation called “high-risk” or “shared clinical decision-making” (SCDM). No vaccines were removed from the schedule. Scientific evidence affirming the effectiveness, safety, and value of childhood immunizations remains unchanged.
The updated Childhood Immunization Schedule by Recommendation Group ([link removed]) lays out these new categories.
Important information for nurses, pharmacists, and physicians who vaccinate:
* Science Remains Unchanged: The balance of risks and benefits are unchanged for vaccines shifted from routine to SCDM. If you recommended these vaccines strongly to your patients before, the classification of SCDM does not require changing your strong recommendation. The routine practice of informing parents of risks and benefits before their decision to vaccinate should continue.
* Out-of-Pocket Costs Remain Unchanged: HHS affirmed in its announcement that all childhood vaccines, including those moved to SCDM, remain covered with no out-of-pocket cost by private insurance plans regulated by the Affordable Care Act (ACA) or federal insurance programs such as Medicaid. Clinicians, hospitals, and states may continue to offer and be paid for administering these vaccines with no out-of-pocket cost to beneficiaries.
* Vaccines for Children (VFC) Program Remains Unchanged: There has been no change to vaccines approved for use through the VFC Program, which covers all vaccines on the schedule, including SCDM.
* HepB Vaccination of Newborns Is Permitted: Providing HepB vaccination at birth for optimal protection from hepatitis B remains a choice for mothers who are test-negative for hepatitis B. The schedule change does not require mothers to delay vaccination.
* SCDM Does NOT Require a Medical Appointment or a Doctor: SCDM simply involves a conversation with a healthcare provider (defined by CDC as a nurse, pharmacist, or physician) about the risks and benefits of receiving a vaccine, which is routine in any vaccination conversation. In the absence of a state regulation specifically limiting the scope of practice of a nurse or pharmacist to provide vaccines classified as SCDM, a child whose parent desires an SCDM vaccine may still be vaccinated by a nurse or in a pharmacy; they do not need to be referred to a medical clinic.
* SCDM Does NOT Require a Parent to Ask for Vaccination: You may recommend vaccines as usual. The decision to vaccinate has always been made by an informed parent and shifting from “routine” to “SCDM” does not change that.
* Healthcare Professional Organization Recommended Childhood Schedules Are Unchanged: The American Academy of Pediatrics (AAP) ([link removed]) and American Academy of Family Physicians (AAFP) ([link removed]) have not changed their childhood vaccine recommendations.
* Vaccine Injury Compensation Program (VICP) Unchanged: There have been no changes to the existing liability protection and patient compensation for vaccine injuries through the VICP, including vaccines shifted to SCDM. Changes to VICP would require a substantial period of time and would require public notice and the opportunity for public comment.
What we don’t know:
* CDC Schedule Details: For example, we await more information about the HPV schedule change to one dose and whether two doses or three doses remain recommended for certain subsets of children, including those with immunocompromise or those who initiate vaccination at older ages. Detailed schedule footnotes for all vaccines previously provided in CDC schedules to cover special cases and the definition of high-risk groups for specific vaccines are unavailable at this time.
* Future Changes: Immunize.org will keep our readers alerted to any changes in our understanding of vaccine injury compensation, insurance coverage, VFC program coverage, state, school, or childcare requirements, and announcements from HHS or CDC.
Related Links
* HHS: Press Release: CDC Acts on Presidential Memorandum to Update Childhood Immunization Schedule ([link removed]) (1/5/26)
* HHS: Childhood Immunization Schedule by Recommendation Group ([link removed]) (1/8/26)
* HHS: Fact Sheet: CDC Childhood Immunization Recommendations ([link removed]) (1/5/26)
* HHS: Assessment of the U.S. Childhood and Adolescent Immunization Schedule Compared to Other Countries ([link removed]) (1/2/26) (PDF, 33 pages)
* White House: Presidential Memoranda: Aligning United States Core Childhood Vaccine Recommendations with Best Practices from Peer, Developed Countries ([link removed]) (12/5/25)
* Immunize.org: Official Guidance: Healthcare Professional Organization Schedules ([link removed]) web section
* The Evidence Collective: In Response: Routine Childhood Vaccination Schedule Announcement ([link removed]): Executive summary and review, with scientific background, common misconceptions, and communication pointers
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“Use of the GSK MenACWY-CRM/MenB-4C Pentavalent Meningococcal Vaccine Among Persons Aged ≥10 Years: Recommendations of the Advisory Committee on Immunization Practices—United States, 2025” published in MMWR
CDC published Use of the GSK MenACWY-CRM/MenB-4C Pentavalent Meningococcal Vaccine Among Persons Aged ≥10 Years: Recommendations of the Advisory Committee on Immunization Practices—United States, 2025 ([link removed]) on January 8 in MMWR. This publication describes the MenABCWY vaccine by GSK (Penmenvy) as an option for use in children and adults age 10 years or older when both MenACWY and MenB (Bexsero) are indicated at the same visit. The recommendation mirrors the earlier recommendation for use of Pfizer’s MenABCWY (Penbraya) when the Trumenba brand of MenB is indicated. The minimum interval between doses of Penmenvy is at least 6 months. A portion of the summary appears below.
Meningococcal disease is a serious bacterial infection caused by Neisseria meningitidis. A new pentavalent meningococcal vaccine (MenACWY-CRM/MenB-4C [Penmenvy, GSK]) protects against N. meningitidis serogroups A, B, C, W, and Y and is licensed for use in persons aged 10–25 years. MenACWY-CRM/MenB-4C is the second pentavalent meningococcal vaccine approved in the United States. . . .
On April 16, 2025, the Advisory Committee on Immunization Practices recommended that, when both quadrivalent (serogroups A, C, W, and Y) and serogroup B meningococcal (MenB) vaccine are indicated concurrently for persons aged ≥10 years, MenACWY-CRM/MenB-4C may be administered instead. . . .
Because different manufacturers’ serogroup B–targeting vaccines are not interchangeable, this recommendation provides a pentavalent vaccine option for persons receiving the GSK MenB vaccine (MenB-4C) for other doses.
[link removed]
Access the MMWR article in HTML ([link removed]) or PDF ([link removed]).
Related Links
* CDC: MMWR main page ([link removed]) providing access to the MMWR family of publications
* Immunize.org: Standing Orders for Administering Meningococcal B Vaccine (MenB) to Adolescents and Adults ([link removed])
* Immunize.org: Vaccines A–Z: Meningococcal ACWY ([link removed]) main page
* Immunize.org: Vaccines A–Z: Meningococcal B ([link removed]) main page
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Respiratory viral activity rises sharply across the country; vaccination reduces risk of severe illness
Acute respiratory illness activity causing people to seek health care is high, led by very high levels of influenza activity. Getting vaccinated or administering RSV preventive antibodies to unprotected babies now can help reduce the risk of severe illness, complications, and hospitalization.
Nationally, for the week ending January 3 ([link removed]):
* Seasonal influenza activity remains elevated across the country, with high or very high influenza-like illness (ILI) reported in 44 jurisdictions ([link removed])
* Eight more children’s influenza-associated deaths were reported during week 53 ([link removed]), for a total of 17 reported pediatric influenza deaths so far this season
* RSV activity is elevated in many areas of the country
* COVID-19 activity is increasing from low levels
This season’s dominant influenza strain, a subtype A/H3N2 virus referred to as subclade K, is antigenically drifted from the A/H3N2 virus selected for the vaccine. Early reports from England ([link removed]) indicate that vaccine effectiveness against influenza-related emergency department (ED) visits and hospital admissions remained within typical ranges (72%–75% reduced risk in children and adolescents, 32%–39% reduced risk in adults). Continue to strongly encourage vaccination.
Level of Respiratory Illness Activity
CDC monitors respiratory illness activity using an acute respiratory illness (ARI) metric. The ARI metric measures ED visits for a wide range of causes of acute respiratory illness, with or without fever, including the common cold, as well as influenza, RSV, and COVID-19. It offers a more complete picture than the influenza-like illness (ILI) metric used in past seasons. Because influenza is leading the respiratory illness wave, the ILI map is shown below:
Emergency Department (ED) Visits for Viral Respiratory Illness
The illustration below shows the proportion of ED visits (ranging from 0 to 10 percent) associated with COVID-19, influenza, and RSV. The horizontal axis shows trends from October 2024 into January 2026 for the three diseases, including the sharp increase in influenza-related visits.
Vaccination against COVID-19, influenza, and RSV reduces the risk of severe illness. Administration of RSV monoclonal antibodies ([link removed]) for all infants younger than 8 months who are unprotected is critical now to provide them immediate protection as RSV activity rises in many communities.
Other CDC Respiratory Illness Resources
* CDC's Respiratory Illness Data Channel ([link removed]) shows state and county level data on respiratory viral activity, associated ED visits, and presence in wastewater.
* CDC's Weekly Flu Vaccination Dashboard ([link removed]) shows vaccination rates by age group. Examples include the Child Flu Vaccination Coverage and Intent (NIS-Flu) ([link removed]) data, which show that:
+ As of December 27, 2025, 42.5% of children ages 6 months through 17 years received a flu vaccination, similar to last season at this same time point (43.5%)
+ Parents of 6% of children reported they definitely planned to get their child vaccinated
+ The percentage of children who received a flu vaccination varies by child's age, mother's education, poverty status, urbanicity, and jurisdiction
Related Links
* CDC: Weekly National Flu Vaccination Dashboard ([link removed]) main page
* CDC: FluView ([link removed]) main page
* CDC: RESP-NET ([link removed]) main page
* CDC: FluVaxView ([link removed]) main page
* 65+ Flu Defense ([link removed]) website
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Measles: 2025 ends with 2,144 confirmed cases; 2026 begins with three cases in two states
As of January 6, CDC reported the first three confirmed measles cases ([link removed]) in two states: North Carolina and South Carolina ([link removed]). During 2025, a total of 2,144 confirmed measles cases were reported in 44 states. There were 49 outbreaks, and of reported confirmed cases, 88% were outbreak-associated.
CDC only requires reporting of laboratory-confirmed measles cases. Cases without laboratory testing for confirmation are not included in these numbers. Actual numbers of cases are, therefore, higher than confirmed case counts.
A map of 2025 measles cases ([link removed]) in the United States, as of January 9, from the Johns Hopkins International Vaccine Access Center ([link removed]), appears below. Their U.S. Measles Tracker ([link removed]) website includes state and county-level data.
Immunize.org offers measles-related resources for the public on several of our affiliated websites:
* VaccineInformation.org: Measles ([link removed]) web page
* LetsGetRealAboutVaccines.org: Measles ([link removed]) web page
* Immunize.org: Vaccines A–Z: Measles ([link removed]) main page
Related Links
* AAP: Fact Checked: The Measles Vaccine Is Safe and Effective ([link removed]) web page
* CDC: Measles Cases and Outbreaks ([link removed]) main page
* CDC: Be Ready for Measles toolkit ([link removed])
* Health Canada: Measles and Rubella Weekly Monitoring Report ([link removed])
* Johns Hopkins Bloomberg School of Public Health Center for Outbreak Response Innovation: Measles Outbreak Response ([link removed]) main page
* Immunize.org: Vaccines A–Z: Measles ([link removed]) main page
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“Can We Give Influenza Vaccine with Other Vaccines?” See the rationale for simultaneous vaccination in this 3-minute video, part of the Ask the Experts Video Series on YouTube.
This week, our featured episode from the Ask the Experts Video Series is titled Can We Give Influenza Vaccine with Other Vaccines? ([link removed]) The video briefly describes CDC’s clinical guidance for the use of influenza vaccines with other vaccines. Any vaccine may be given on the same day or any day before or after influenza vaccination, at a different anatomic site.
The 3-minute video is available on our YouTube channel ([link removed]), along with our full collection of quick video answers to popular Ask the Experts ([link removed]) questions.
Like, follow, and share Immunize.org’s social media accounts and encourage colleagues and others interested in vaccination to do likewise.
* Facebook at ImmunizeOrg ([link removed])
* Instagram at ImmunizeOrg ([link removed])
* LinkedIn at ImmunizeOrg ([link removed])
* YouTube at ImmunizeOrg ([link removed])
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Journalists interview Immunize.org experts
Journalists seek out Immunize.org experts to help explain vaccines to the public and policy makers. We help the media understand and communicate the complex work vaccinators do. Here is a recent citation.
* Science: The Trump Administration Says Some Approved Childhood Vaccines Need Better Studies. Scientists Disagree ([link removed]) (1/8/26)
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Vaccines in the news
These recent articles convey the potential risks of vaccine-preventable diseases and the importance of vaccination.
* NBC News: Flu is Particularly Hard on Kids this Season ([link removed]) (1/9/2026)
* Fox News: Measles Outbreak Explodes in South Carolina; Multiple People Hospitalized as Cases Surpass 200 ([link removed]) (1/6/26)
* Annenberg Public Policy Center: CDC Urges ‘Shared Decision-Making’ on Some Childhood Vaccines; Many Unclear About What That Means ([link removed]) (1/5/26)
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Immunize.org Website and Clinical Resources
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Spotlight on the website: Publication archives
Our readers will find immunization history preserved in Immunize.org’s archive of our periodical publications, dating back to 1994.
After clicking “News & Updates,” the Publication Archives ([link removed]) icon provides access to Immunize.org’s periodicals through the years.
You can scroll the page shown above to see publication descriptions. Or you can use the links on the far left or far right to jump to specific content.
The archive contains the following publications:
IZ Express ([link removed]): All issues since inception in 1997. These are searchable by year, month, or keyword. The name changed from IAC Express to IZ Express in January 2022.
Needle Tips ([link removed]): Mailed to healthcare professionals from 1994 through 2010. From 2011 through November 2017, it was an online-only publication.
Technically Speaking ([link removed]): This column in the Vaccine Education Center’s Vaccine Update for Healthcare Professionals covered practical topics in immunization. Our archive ranges from 2016 to 2021.
Vaccinate Adults ([link removed]): This publication focused on increasing adult immunization. It started as a semiannual print publication in 1997 and became a quarterly online publication in 2010, running through 2017.
Vaccinate Women ([link removed]): This publication was published annually from 2002 to 2008 for obstetrics and gynecology professionals.
Vaccinating Adults: A Step-by-Step Guide ([link removed]): Published in 2017, this guide is designed to help implement or enhance adult immunization services in healthcare settings.
We hope educators, researchers, and curious clinicians find these historical resources interesting and valuable to your work.
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Recap: Immunize.org updates “Standing Orders for Administering Meningococcal B Vaccine (MenB) to Adolescents and Adults”
Immunize.org updated its Standing Orders for Administering Meningococcal B Vaccine (MenB) to Adolescents and Adults ([link removed]) to note the option to use pentavalent MenABCWY vaccine if a patient age 10 years or older needs both MenB and MenACWY vaccines in the same visit.
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Recap: Immunize.org updates parent handout, “Top Ten Reasons to Protect Your Child by Vaccinating”
Immunize.org updated its parent handout, Top Ten Reasons to Protect Your Child by Vaccinating ([link removed]). Changes include adding RSV protection in item 3 and making minor wording adjustments.
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Recap: Immunize.org updates “Don't Be Guilty of These Preventable Errors in Vaccine Administration!”
Immunize.org reviewed Don't Be Guilty of These Preventable Errors in Vaccine Administration! ([link removed]) to incorporate updated CDC MMRV vaccine recommendations limiting its use to children age 4 years or older. It also incorporates minor changes to improve wording.
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Recap: Immunize.org updates “Questions and Answers” resource on varicella
Immunize.org updated Varicella (Chickenpox): Questions and Answers ([link removed]) resource for patients and caregivers to incorporate updated MMRV vaccine recommendations on page three, which now states:
In the several years following the licensure of the combined measles-mumps-rubella (MMR) and varicella vaccines in 2005, surveillance of side effects showed that children who got their first dose as the combined product (MMRV) had more fevers and fever-related seizures (about 1 in 1,250) than children who got the first dose as separate shots of MMR and varicella on the same day. As a result, CDC preferred use of separate MMR and varicella vaccines for the first dose in the 2-dose series. In June of 2025, CDC recommended use of separate MMR and varicella vaccines for all doses given before age 4 years, although no increased risk of febrile seizures has been detected when using MMRV as a second dose in the series. The use of combination vaccine (MMRV) remains generally preferred over separate injections for children who are receiving their second dose or their first dose when age 4 through 12 years.
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Featured Resources
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Recap: Immunize.org adds vaccine schedules and searchable database of recommendations published by healthcare professional organizations
Some healthcare professional organizations issue evidence-based vaccination guidance for their patient populations. They include the American Academy of Pediatrics (AAP), the American College of Obstetricians and Gynecologists (ACOG), the American Academy of Family Practitioners (AAFP), and others. To better support vaccination providers and educators who rely on our resources, at the end of December 2025 Immunize.org launched two new pages to connect with healthcare professional organization guidance in the new Healthcare Professional Organizations ([link removed]) section on our website.
In this section, you will find links to:
* Healthcare Professional Organization Recommended Schedules ([link removed]): this web page displays current immunization schedules published by healthcare professional organizations for their patient populations
* Healthcare Professional Organization Vaccine Recommendations ([link removed]) searchable database sorted into two tabs:
+ Comprehensive Recommendations ([link removed]): this tab lists broad recommendations for a specific population, such as those who are immunocompromised
+ Vaccine-Specific Recommendations ([link removed]): this web page displays a searchable listing of recommendations published by healthcare professional organizations for the population they serve
These new pages are intended to help you make well-informed clinical decisions about vaccination by offering easy access to evidence-based clinical guidance. Visit Immunize.org's Healthcare Professional Organizations ([link removed]) to view these two new web pages.
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Updated 65+ Flu Defense website offers resources for healthcare professionals serving older adults
Confident healthcare provider recommendations for influenza vaccine are powerfully persuasive. As the nation faces a challenging influenza season, Immunize.org, in collaboration with CSL Seqirus, updated the 65+ Flu Defense ([link removed]) website to help you maximize patient protection.
This helpful site includes information, tools, and tips for communicating with adults age 65 and older about the burden and severity of influenza. Resources include:
* Influenza in Adults 65+: The Facts ([link removed])
* Influenza Vaccination: Questions Patients Aged 65 and Older Frequently Ask Their HCP ([link removed])
* The Importance of Preventing Influenza and COVID-19 ([link removed])
A clinician recommendation is the most important reason why a person will get vaccinated. Check out the updated 65+ Flu Defense ([link removed]) website to assist your ongoing efforts in protecting this vulnerable population.
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Immunize.org's elegant "Vaccination Saves Lives" blue enamel pins make wonderful workplace recognitions
Immunize.org is pleased to offer our new lapel pin. Our “Vaccination Saves Lives” pins ([link removed]) are meaningful gifts for people who understand that lives are not saved by vaccines on a shelf, but by the act of vaccination. The pin makes a refined statement in rich blue enamel with gold lettering and edges, measuring 1.65" x 0.75".
Select the design that best suits how you plan to use your pin:
* Double stick-through posts ([link removed]): Two posts slide through fabric and are held securely by either rubber or locking-metal backings. Both types of backing are provided in the package.
* New! Magnetic clasp ([link removed]): Hold the pin firmly in place without piercing clothing.
Be first in your office to wear these elegant new pins on clothing, white coats, backpacks, or tote bags to remind everyone you meet of the value of vaccination.
Click here for "Vaccination Saves Lives" pin pricing ([link removed]) and ordering information.
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Needle anxiety is common at any age. Use Immunize.org’s clinical resources to offer a positive vaccination experience.
In Clinical Resources: Improving the Vaccination Experience ([link removed]), Immunize.org provides print and video tools to create a positive vaccination experience and ease injection anxiety in children and adults. Links to additional resources from trusted partner organizations are also provided.
The web page links to eight printable resources ([link removed]) on addressing vaccination anxiety (four for providers, four for recipients—also available in Spanish), two in-depth webinars, and six brief videos (listed below). As with all Immunize.org resources, these are free to download, link, copy, and share.
The video topics include:
* How to Administer Multiple Intramuscular Vaccines to Adults During One Visit ([link removed])
* Using Enhanced Screening Checklists for Contraindications to Vaccination ([link removed])
* Addressing Vaccination Anxiety for Infants: Strategies for Vaccine Recipients and Caregivers ([link removed])
* Addressing Vaccination Anxiety: Strategies for Healthcare Professionals ([link removed])
* Fainting Related to Vaccination: What You Need to Know ([link removed])
* Addressing Vaccination Anxiety for Children: Strategies for Vaccine Recipients and Caregivers ([link removed])
Related Link
* Immunize.org: Clinical Resources: Improving the Vaccination Experience ([link removed]) web page
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Help Immunize.org reach more vaccinators through your social media networks. Follow us and share our posts on Facebook, Instagram, and LinkedIn!
Immunize.org offers a social media program to highlight our educational resources for a widespread audience of vaccinators. Our social media channels now feature our most popular printable resources and Ask the Experts questions, as well as announcements important to frontline vaccinators. Please view and share our newest feature, the Ask the Experts Video Series ([link removed]).
Like, follow, and share Immunize.org’s social media accounts and encourage colleagues and others interested in vaccination to do likewise:
* Facebook at ImmunizeOrg ([link removed])
* Instagram at ImmunizeOrg ([link removed])
* LinkedIn at Immunize.org ([link removed])
* YouTube at ImmunizeOrg ([link removed])
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Notable Publications
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“Updated Evidence for COVID-19, RSV, and Influenza Vaccines for 2025–2026” published in New England Journal of Medicine
In its October 29 issue, New England Journal of Medicine published Updated Evidence for COVID-19, RSV, and Influenza Vaccines for 2025–2026 ([link removed]). A portion of the methods, results, and conclusions sections appear below.
We conducted a systematic review of U.S.-licensed immunizations against coronavirus disease 2019 (COVID-19), respiratory syncytial virus (RSV), and influenza. We searched databases on PubMed/MEDLINE, Embase, and Web of Science for updates of the most recent review by the Advisory Committee on Immunization Practices (ACIP) Evidence-to-Recommendations for each disease, which was performed during the 2023–2024 period. Outcomes included vaccine efficacy and effectiveness against hospitalization, other clinical end points, and safety. . . .
Of 17,263 identified references, 511 studies met the inclusion criteria. . . .
Ongoing peer-reviewed evidence supports the safety and effectiveness of immunizations against COVID-19, RSV, and influenza during the 2025–2026 season.
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Upcoming Events
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Virtual: Register for Immunize.org Website Office Hours. Join a 30-minute discussion about our new Official Guidance: Healthcare Professional Organization Schedules content on February 11 at 4:00 p.m. (ET) or February 12 at 12:00 p.m. (ET). Recorded sessions archived.
To learn simple tips and tricks for using our websites efficiently, please register for our next set of Website Office Hours on Wednesday, February 11, at 4:00 p.m. (ET) ([link removed]) or Thursday, February 12, at 12:00 p.m. (ET) ([link removed]). The same content will be covered in both sessions.
We will open each 30-minute session with a short, live demonstration on navigating our new Official Guidance: Healthcare Professional Organization Schedules ([link removed]) website section. You can submit questions when you register or live on Zoom during the session.
Register today for Immunize.org Website Office Hours (content is the same for both):
* Wednesday, February 11, at 4:00 p.m. (ET) ([link removed])
* Thursday, February 12, at 12:00 p.m. (ET) ([link removed])
The archive of previous Website Office Hours content ([link removed]) is posted at Immunize.org’s "Webinars & Videos" page.
Mark your calendar ([link removed]) for future Immunize.org Website Office Hours.
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For more upcoming events, visit our Calendar of Events ([link removed]).
Editorial Information
Editor-in-Chief
Kelly L. Moore, MD, MPH
Managing Editor
John D. Gräbenstein, RPh, PhD
Associate Editor
Sharon G. Humiston, MD, MPH
Writer/Publication Coordinator
Taryn Chapman, MS
Courtnay Londo, MA
Style and Copy Editor
Marian Deegan, JD
Web Edition Managers
Arkady Shakhnovich
Jermaine Royes
Technical Reviewer
Kayla Ohlde
About IZ Express
Immunize.org welcomes redistribution of this issue of IZ Express or selected articles.
When you do so, please add a note that Immunize.org is the source of the material and provide a link to this issue ([link removed]).
IZ Express is supported in part by Grant No. NH23IP922654 from the National Center for Immunization and Respiratory Diseases, CDC. Its contents are solely the responsibility of Immunize.org and do not necessarily represent the official views of CDC.
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Issue 1,852: January 14, 2026
Top Stories
* HHS and CDC release 2026 childhood immunization schedule; what it means today for frontline providers
* “Use of the GSK MenACWY-CRM/MenB-4C Pentavalent Meningococcal Vaccine Among Persons Aged ≥10 Years: Recommendations of the Advisory Committee on Immunization Practices—United States, 2025” published in MMWR
* Respiratory viral activity rises sharply across the country; vaccination reduces risk of severe illness
* Measles: 2025 ends with 2,144 confirmed cases; 2026 begins with three cases in two states
* “Can We Give Influenza Vaccine with Other Vaccines?” See the rationale for simultaneous vaccination in this 3-minute video, part of the Ask the Experts Video Series on YouTube.
* Journalists interview Immunize.org experts
* Vaccines in the news
Immunize.org Website and Clinical Resources
* Spotlight on the website: Publication archives
* Recap: Immunize.org updates “Standing Orders for Administering Meningococcal B Vaccine (MenB) to Adolescents and Adults”
* Recap: Immunize.org updates parent handout, “Top Ten Reasons to Protect Your Child by Vaccinating”
* Recap: Immunize.org updates “Don't Be Guilty of These Preventable Errors in Vaccine Administration!”
* Recap: Immunize.org updates “Questions and Answers” resource on varicella
Featured Resources
* Recap: Immunize.org adds vaccine schedules and searchable database of recommendations published by healthcare professional organizations
* Updated 65+ Flu Defense website offers resources for healthcare professionals serving older adults
* Immunize.org's elegant "Vaccination Saves Lives" blue enamel pins make wonderful workplace recognitions
* Needle anxiety is common at any age. Use Immunize.org’s clinical resources to offer a positive vaccination experience.
* Help Immunize.org reach more vaccinators through your social media networks. Follow us and share our posts on Facebook, Instagram, and LinkedIn!
Notable Publications
* “Updated Evidence for COVID-19, RSV, and Influenza Vaccines for 2025–2026” published in New England Journal of Medicine
Upcoming Events
* Virtual: Register for Immunize.org Website Office Hours. Join a 30-minute discussion about our new Official Guidance: Healthcare Professional Organization Schedules content on February 11 at 4:00 p.m. (ET) or February 12 at 12:00 p.m. (ET). Recorded sessions archived.
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Top Stories
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HHS and CDC release 2026 childhood immunization schedule; what it means today for frontline providers
On January 5, HHS and CDC announced changes to the childhood immunization schedule ([link removed]), following a Presidential directive ([link removed]) to align U.S. recommendations with those of “peer, developed countries.” This resulted in the acting CDC director’s decision to retain, as routinely recommended, the vaccines routinely recommended by other countries selected by HHS for evaluation. Other vaccines on the previous CDC schedule were shifted to categories of recommendation called “high-risk” or “shared clinical decision-making” (SCDM). No vaccines were removed from the schedule. Scientific evidence affirming the effectiveness, safety, and value of childhood immunizations remains unchanged.
The updated Childhood Immunization Schedule by Recommendation Group ([link removed]) lays out these new categories.
Important information for nurses, pharmacists, and physicians who vaccinate:
* Science Remains Unchanged: The balance of risks and benefits are unchanged for vaccines shifted from routine to SCDM. If you recommended these vaccines strongly to your patients before, the classification of SCDM does not require changing your strong recommendation. The routine practice of informing parents of risks and benefits before their decision to vaccinate should continue.
* Out-of-Pocket Costs Remain Unchanged: HHS affirmed in its announcement that all childhood vaccines, including those moved to SCDM, remain covered with no out-of-pocket cost by private insurance plans regulated by the Affordable Care Act (ACA) or federal insurance programs such as Medicaid. Clinicians, hospitals, and states may continue to offer and be paid for administering these vaccines with no out-of-pocket cost to beneficiaries.
* Vaccines for Children (VFC) Program Remains Unchanged: There has been no change to vaccines approved for use through the VFC Program, which covers all vaccines on the schedule, including SCDM.
* HepB Vaccination of Newborns Is Permitted: Providing HepB vaccination at birth for optimal protection from hepatitis B remains a choice for mothers who are test-negative for hepatitis B. The schedule change does not require mothers to delay vaccination.
* SCDM Does NOT Require a Medical Appointment or a Doctor: SCDM simply involves a conversation with a healthcare provider (defined by CDC as a nurse, pharmacist, or physician) about the risks and benefits of receiving a vaccine, which is routine in any vaccination conversation. In the absence of a state regulation specifically limiting the scope of practice of a nurse or pharmacist to provide vaccines classified as SCDM, a child whose parent desires an SCDM vaccine may still be vaccinated by a nurse or in a pharmacy; they do not need to be referred to a medical clinic.
* SCDM Does NOT Require a Parent to Ask for Vaccination: You may recommend vaccines as usual. The decision to vaccinate has always been made by an informed parent and shifting from “routine” to “SCDM” does not change that.
* Healthcare Professional Organization Recommended Childhood Schedules Are Unchanged: The American Academy of Pediatrics (AAP) ([link removed]) and American Academy of Family Physicians (AAFP) ([link removed]) have not changed their childhood vaccine recommendations.
* Vaccine Injury Compensation Program (VICP) Unchanged: There have been no changes to the existing liability protection and patient compensation for vaccine injuries through the VICP, including vaccines shifted to SCDM. Changes to VICP would require a substantial period of time and would require public notice and the opportunity for public comment.
What we don’t know:
* CDC Schedule Details: For example, we await more information about the HPV schedule change to one dose and whether two doses or three doses remain recommended for certain subsets of children, including those with immunocompromise or those who initiate vaccination at older ages. Detailed schedule footnotes for all vaccines previously provided in CDC schedules to cover special cases and the definition of high-risk groups for specific vaccines are unavailable at this time.
* Future Changes: Immunize.org will keep our readers alerted to any changes in our understanding of vaccine injury compensation, insurance coverage, VFC program coverage, state, school, or childcare requirements, and announcements from HHS or CDC.
Related Links
* HHS: Press Release: CDC Acts on Presidential Memorandum to Update Childhood Immunization Schedule ([link removed]) (1/5/26)
* HHS: Childhood Immunization Schedule by Recommendation Group ([link removed]) (1/8/26)
* HHS: Fact Sheet: CDC Childhood Immunization Recommendations ([link removed]) (1/5/26)
* HHS: Assessment of the U.S. Childhood and Adolescent Immunization Schedule Compared to Other Countries ([link removed]) (1/2/26) (PDF, 33 pages)
* White House: Presidential Memoranda: Aligning United States Core Childhood Vaccine Recommendations with Best Practices from Peer, Developed Countries ([link removed]) (12/5/25)
* Immunize.org: Official Guidance: Healthcare Professional Organization Schedules ([link removed]) web section
* The Evidence Collective: In Response: Routine Childhood Vaccination Schedule Announcement ([link removed]): Executive summary and review, with scientific background, common misconceptions, and communication pointers
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“Use of the GSK MenACWY-CRM/MenB-4C Pentavalent Meningococcal Vaccine Among Persons Aged ≥10 Years: Recommendations of the Advisory Committee on Immunization Practices—United States, 2025” published in MMWR
CDC published Use of the GSK MenACWY-CRM/MenB-4C Pentavalent Meningococcal Vaccine Among Persons Aged ≥10 Years: Recommendations of the Advisory Committee on Immunization Practices—United States, 2025 ([link removed]) on January 8 in MMWR. This publication describes the MenABCWY vaccine by GSK (Penmenvy) as an option for use in children and adults age 10 years or older when both MenACWY and MenB (Bexsero) are indicated at the same visit. The recommendation mirrors the earlier recommendation for use of Pfizer’s MenABCWY (Penbraya) when the Trumenba brand of MenB is indicated. The minimum interval between doses of Penmenvy is at least 6 months. A portion of the summary appears below.
Meningococcal disease is a serious bacterial infection caused by Neisseria meningitidis. A new pentavalent meningococcal vaccine (MenACWY-CRM/MenB-4C [Penmenvy, GSK]) protects against N. meningitidis serogroups A, B, C, W, and Y and is licensed for use in persons aged 10–25 years. MenACWY-CRM/MenB-4C is the second pentavalent meningococcal vaccine approved in the United States. . . .
On April 16, 2025, the Advisory Committee on Immunization Practices recommended that, when both quadrivalent (serogroups A, C, W, and Y) and serogroup B meningococcal (MenB) vaccine are indicated concurrently for persons aged ≥10 years, MenACWY-CRM/MenB-4C may be administered instead. . . .
Because different manufacturers’ serogroup B–targeting vaccines are not interchangeable, this recommendation provides a pentavalent vaccine option for persons receiving the GSK MenB vaccine (MenB-4C) for other doses.
[link removed]
Access the MMWR article in HTML ([link removed]) or PDF ([link removed]).
Related Links
* CDC: MMWR main page ([link removed]) providing access to the MMWR family of publications
* Immunize.org: Standing Orders for Administering Meningococcal B Vaccine (MenB) to Adolescents and Adults ([link removed])
* Immunize.org: Vaccines A–Z: Meningococcal ACWY ([link removed]) main page
* Immunize.org: Vaccines A–Z: Meningococcal B ([link removed]) main page
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Respiratory viral activity rises sharply across the country; vaccination reduces risk of severe illness
Acute respiratory illness activity causing people to seek health care is high, led by very high levels of influenza activity. Getting vaccinated or administering RSV preventive antibodies to unprotected babies now can help reduce the risk of severe illness, complications, and hospitalization.
Nationally, for the week ending January 3 ([link removed]):
* Seasonal influenza activity remains elevated across the country, with high or very high influenza-like illness (ILI) reported in 44 jurisdictions ([link removed])
* Eight more children’s influenza-associated deaths were reported during week 53 ([link removed]), for a total of 17 reported pediatric influenza deaths so far this season
* RSV activity is elevated in many areas of the country
* COVID-19 activity is increasing from low levels
This season’s dominant influenza strain, a subtype A/H3N2 virus referred to as subclade K, is antigenically drifted from the A/H3N2 virus selected for the vaccine. Early reports from England ([link removed]) indicate that vaccine effectiveness against influenza-related emergency department (ED) visits and hospital admissions remained within typical ranges (72%–75% reduced risk in children and adolescents, 32%–39% reduced risk in adults). Continue to strongly encourage vaccination.
Level of Respiratory Illness Activity
CDC monitors respiratory illness activity using an acute respiratory illness (ARI) metric. The ARI metric measures ED visits for a wide range of causes of acute respiratory illness, with or without fever, including the common cold, as well as influenza, RSV, and COVID-19. It offers a more complete picture than the influenza-like illness (ILI) metric used in past seasons. Because influenza is leading the respiratory illness wave, the ILI map is shown below:
Emergency Department (ED) Visits for Viral Respiratory Illness
The illustration below shows the proportion of ED visits (ranging from 0 to 10 percent) associated with COVID-19, influenza, and RSV. The horizontal axis shows trends from October 2024 into January 2026 for the three diseases, including the sharp increase in influenza-related visits.
Vaccination against COVID-19, influenza, and RSV reduces the risk of severe illness. Administration of RSV monoclonal antibodies ([link removed]) for all infants younger than 8 months who are unprotected is critical now to provide them immediate protection as RSV activity rises in many communities.
Other CDC Respiratory Illness Resources
* CDC's Respiratory Illness Data Channel ([link removed]) shows state and county level data on respiratory viral activity, associated ED visits, and presence in wastewater.
* CDC's Weekly Flu Vaccination Dashboard ([link removed]) shows vaccination rates by age group. Examples include the Child Flu Vaccination Coverage and Intent (NIS-Flu) ([link removed]) data, which show that:
+ As of December 27, 2025, 42.5% of children ages 6 months through 17 years received a flu vaccination, similar to last season at this same time point (43.5%)
+ Parents of 6% of children reported they definitely planned to get their child vaccinated
+ The percentage of children who received a flu vaccination varies by child's age, mother's education, poverty status, urbanicity, and jurisdiction
Related Links
* CDC: Weekly National Flu Vaccination Dashboard ([link removed]) main page
* CDC: FluView ([link removed]) main page
* CDC: RESP-NET ([link removed]) main page
* CDC: FluVaxView ([link removed]) main page
* 65+ Flu Defense ([link removed]) website
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Measles: 2025 ends with 2,144 confirmed cases; 2026 begins with three cases in two states
As of January 6, CDC reported the first three confirmed measles cases ([link removed]) in two states: North Carolina and South Carolina ([link removed]). During 2025, a total of 2,144 confirmed measles cases were reported in 44 states. There were 49 outbreaks, and of reported confirmed cases, 88% were outbreak-associated.
CDC only requires reporting of laboratory-confirmed measles cases. Cases without laboratory testing for confirmation are not included in these numbers. Actual numbers of cases are, therefore, higher than confirmed case counts.
A map of 2025 measles cases ([link removed]) in the United States, as of January 9, from the Johns Hopkins International Vaccine Access Center ([link removed]), appears below. Their U.S. Measles Tracker ([link removed]) website includes state and county-level data.
Immunize.org offers measles-related resources for the public on several of our affiliated websites:
* VaccineInformation.org: Measles ([link removed]) web page
* LetsGetRealAboutVaccines.org: Measles ([link removed]) web page
* Immunize.org: Vaccines A–Z: Measles ([link removed]) main page
Related Links
* AAP: Fact Checked: The Measles Vaccine Is Safe and Effective ([link removed]) web page
* CDC: Measles Cases and Outbreaks ([link removed]) main page
* CDC: Be Ready for Measles toolkit ([link removed])
* Health Canada: Measles and Rubella Weekly Monitoring Report ([link removed])
* Johns Hopkins Bloomberg School of Public Health Center for Outbreak Response Innovation: Measles Outbreak Response ([link removed]) main page
* Immunize.org: Vaccines A–Z: Measles ([link removed]) main page
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“Can We Give Influenza Vaccine with Other Vaccines?” See the rationale for simultaneous vaccination in this 3-minute video, part of the Ask the Experts Video Series on YouTube.
This week, our featured episode from the Ask the Experts Video Series is titled Can We Give Influenza Vaccine with Other Vaccines? ([link removed]) The video briefly describes CDC’s clinical guidance for the use of influenza vaccines with other vaccines. Any vaccine may be given on the same day or any day before or after influenza vaccination, at a different anatomic site.
The 3-minute video is available on our YouTube channel ([link removed]), along with our full collection of quick video answers to popular Ask the Experts ([link removed]) questions.
Like, follow, and share Immunize.org’s social media accounts and encourage colleagues and others interested in vaccination to do likewise.
* Facebook at ImmunizeOrg ([link removed])
* Instagram at ImmunizeOrg ([link removed])
* LinkedIn at ImmunizeOrg ([link removed])
* YouTube at ImmunizeOrg ([link removed])
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Journalists interview Immunize.org experts
Journalists seek out Immunize.org experts to help explain vaccines to the public and policy makers. We help the media understand and communicate the complex work vaccinators do. Here is a recent citation.
* Science: The Trump Administration Says Some Approved Childhood Vaccines Need Better Studies. Scientists Disagree ([link removed]) (1/8/26)
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Vaccines in the news
These recent articles convey the potential risks of vaccine-preventable diseases and the importance of vaccination.
* NBC News: Flu is Particularly Hard on Kids this Season ([link removed]) (1/9/2026)
* Fox News: Measles Outbreak Explodes in South Carolina; Multiple People Hospitalized as Cases Surpass 200 ([link removed]) (1/6/26)
* Annenberg Public Policy Center: CDC Urges ‘Shared Decision-Making’ on Some Childhood Vaccines; Many Unclear About What That Means ([link removed]) (1/5/26)
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Immunize.org Website and Clinical Resources
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Spotlight on the website: Publication archives
Our readers will find immunization history preserved in Immunize.org’s archive of our periodical publications, dating back to 1994.
After clicking “News & Updates,” the Publication Archives ([link removed]) icon provides access to Immunize.org’s periodicals through the years.
You can scroll the page shown above to see publication descriptions. Or you can use the links on the far left or far right to jump to specific content.
The archive contains the following publications:
IZ Express ([link removed]): All issues since inception in 1997. These are searchable by year, month, or keyword. The name changed from IAC Express to IZ Express in January 2022.
Needle Tips ([link removed]): Mailed to healthcare professionals from 1994 through 2010. From 2011 through November 2017, it was an online-only publication.
Technically Speaking ([link removed]): This column in the Vaccine Education Center’s Vaccine Update for Healthcare Professionals covered practical topics in immunization. Our archive ranges from 2016 to 2021.
Vaccinate Adults ([link removed]): This publication focused on increasing adult immunization. It started as a semiannual print publication in 1997 and became a quarterly online publication in 2010, running through 2017.
Vaccinate Women ([link removed]): This publication was published annually from 2002 to 2008 for obstetrics and gynecology professionals.
Vaccinating Adults: A Step-by-Step Guide ([link removed]): Published in 2017, this guide is designed to help implement or enhance adult immunization services in healthcare settings.
We hope educators, researchers, and curious clinicians find these historical resources interesting and valuable to your work.
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Recap: Immunize.org updates “Standing Orders for Administering Meningococcal B Vaccine (MenB) to Adolescents and Adults”
Immunize.org updated its Standing Orders for Administering Meningococcal B Vaccine (MenB) to Adolescents and Adults ([link removed]) to note the option to use pentavalent MenABCWY vaccine if a patient age 10 years or older needs both MenB and MenACWY vaccines in the same visit.
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Recap: Immunize.org updates parent handout, “Top Ten Reasons to Protect Your Child by Vaccinating”
Immunize.org updated its parent handout, Top Ten Reasons to Protect Your Child by Vaccinating ([link removed]). Changes include adding RSV protection in item 3 and making minor wording adjustments.
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Recap: Immunize.org updates “Don't Be Guilty of These Preventable Errors in Vaccine Administration!”
Immunize.org reviewed Don't Be Guilty of These Preventable Errors in Vaccine Administration! ([link removed]) to incorporate updated CDC MMRV vaccine recommendations limiting its use to children age 4 years or older. It also incorporates minor changes to improve wording.
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Recap: Immunize.org updates “Questions and Answers” resource on varicella
Immunize.org updated Varicella (Chickenpox): Questions and Answers ([link removed]) resource for patients and caregivers to incorporate updated MMRV vaccine recommendations on page three, which now states:
In the several years following the licensure of the combined measles-mumps-rubella (MMR) and varicella vaccines in 2005, surveillance of side effects showed that children who got their first dose as the combined product (MMRV) had more fevers and fever-related seizures (about 1 in 1,250) than children who got the first dose as separate shots of MMR and varicella on the same day. As a result, CDC preferred use of separate MMR and varicella vaccines for the first dose in the 2-dose series. In June of 2025, CDC recommended use of separate MMR and varicella vaccines for all doses given before age 4 years, although no increased risk of febrile seizures has been detected when using MMRV as a second dose in the series. The use of combination vaccine (MMRV) remains generally preferred over separate injections for children who are receiving their second dose or their first dose when age 4 through 12 years.
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Featured Resources
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Recap: Immunize.org adds vaccine schedules and searchable database of recommendations published by healthcare professional organizations
Some healthcare professional organizations issue evidence-based vaccination guidance for their patient populations. They include the American Academy of Pediatrics (AAP), the American College of Obstetricians and Gynecologists (ACOG), the American Academy of Family Practitioners (AAFP), and others. To better support vaccination providers and educators who rely on our resources, at the end of December 2025 Immunize.org launched two new pages to connect with healthcare professional organization guidance in the new Healthcare Professional Organizations ([link removed]) section on our website.
In this section, you will find links to:
* Healthcare Professional Organization Recommended Schedules ([link removed]): this web page displays current immunization schedules published by healthcare professional organizations for their patient populations
* Healthcare Professional Organization Vaccine Recommendations ([link removed]) searchable database sorted into two tabs:
+ Comprehensive Recommendations ([link removed]): this tab lists broad recommendations for a specific population, such as those who are immunocompromised
+ Vaccine-Specific Recommendations ([link removed]): this web page displays a searchable listing of recommendations published by healthcare professional organizations for the population they serve
These new pages are intended to help you make well-informed clinical decisions about vaccination by offering easy access to evidence-based clinical guidance. Visit Immunize.org's Healthcare Professional Organizations ([link removed]) to view these two new web pages.
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Updated 65+ Flu Defense website offers resources for healthcare professionals serving older adults
Confident healthcare provider recommendations for influenza vaccine are powerfully persuasive. As the nation faces a challenging influenza season, Immunize.org, in collaboration with CSL Seqirus, updated the 65+ Flu Defense ([link removed]) website to help you maximize patient protection.
This helpful site includes information, tools, and tips for communicating with adults age 65 and older about the burden and severity of influenza. Resources include:
* Influenza in Adults 65+: The Facts ([link removed])
* Influenza Vaccination: Questions Patients Aged 65 and Older Frequently Ask Their HCP ([link removed])
* The Importance of Preventing Influenza and COVID-19 ([link removed])
A clinician recommendation is the most important reason why a person will get vaccinated. Check out the updated 65+ Flu Defense ([link removed]) website to assist your ongoing efforts in protecting this vulnerable population.
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Immunize.org's elegant "Vaccination Saves Lives" blue enamel pins make wonderful workplace recognitions
Immunize.org is pleased to offer our new lapel pin. Our “Vaccination Saves Lives” pins ([link removed]) are meaningful gifts for people who understand that lives are not saved by vaccines on a shelf, but by the act of vaccination. The pin makes a refined statement in rich blue enamel with gold lettering and edges, measuring 1.65" x 0.75".
Select the design that best suits how you plan to use your pin:
* Double stick-through posts ([link removed]): Two posts slide through fabric and are held securely by either rubber or locking-metal backings. Both types of backing are provided in the package.
* New! Magnetic clasp ([link removed]): Hold the pin firmly in place without piercing clothing.
Be first in your office to wear these elegant new pins on clothing, white coats, backpacks, or tote bags to remind everyone you meet of the value of vaccination.
Click here for "Vaccination Saves Lives" pin pricing ([link removed]) and ordering information.
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Needle anxiety is common at any age. Use Immunize.org’s clinical resources to offer a positive vaccination experience.
In Clinical Resources: Improving the Vaccination Experience ([link removed]), Immunize.org provides print and video tools to create a positive vaccination experience and ease injection anxiety in children and adults. Links to additional resources from trusted partner organizations are also provided.
The web page links to eight printable resources ([link removed]) on addressing vaccination anxiety (four for providers, four for recipients—also available in Spanish), two in-depth webinars, and six brief videos (listed below). As with all Immunize.org resources, these are free to download, link, copy, and share.
The video topics include:
* How to Administer Multiple Intramuscular Vaccines to Adults During One Visit ([link removed])
* Using Enhanced Screening Checklists for Contraindications to Vaccination ([link removed])
* Addressing Vaccination Anxiety for Infants: Strategies for Vaccine Recipients and Caregivers ([link removed])
* Addressing Vaccination Anxiety: Strategies for Healthcare Professionals ([link removed])
* Fainting Related to Vaccination: What You Need to Know ([link removed])
* Addressing Vaccination Anxiety for Children: Strategies for Vaccine Recipients and Caregivers ([link removed])
Related Link
* Immunize.org: Clinical Resources: Improving the Vaccination Experience ([link removed]) web page
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Help Immunize.org reach more vaccinators through your social media networks. Follow us and share our posts on Facebook, Instagram, and LinkedIn!
Immunize.org offers a social media program to highlight our educational resources for a widespread audience of vaccinators. Our social media channels now feature our most popular printable resources and Ask the Experts questions, as well as announcements important to frontline vaccinators. Please view and share our newest feature, the Ask the Experts Video Series ([link removed]).
Like, follow, and share Immunize.org’s social media accounts and encourage colleagues and others interested in vaccination to do likewise:
* Facebook at ImmunizeOrg ([link removed])
* Instagram at ImmunizeOrg ([link removed])
* LinkedIn at Immunize.org ([link removed])
* YouTube at ImmunizeOrg ([link removed])
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Notable Publications
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“Updated Evidence for COVID-19, RSV, and Influenza Vaccines for 2025–2026” published in New England Journal of Medicine
In its October 29 issue, New England Journal of Medicine published Updated Evidence for COVID-19, RSV, and Influenza Vaccines for 2025–2026 ([link removed]). A portion of the methods, results, and conclusions sections appear below.
We conducted a systematic review of U.S.-licensed immunizations against coronavirus disease 2019 (COVID-19), respiratory syncytial virus (RSV), and influenza. We searched databases on PubMed/MEDLINE, Embase, and Web of Science for updates of the most recent review by the Advisory Committee on Immunization Practices (ACIP) Evidence-to-Recommendations for each disease, which was performed during the 2023–2024 period. Outcomes included vaccine efficacy and effectiveness against hospitalization, other clinical end points, and safety. . . .
Of 17,263 identified references, 511 studies met the inclusion criteria. . . .
Ongoing peer-reviewed evidence supports the safety and effectiveness of immunizations against COVID-19, RSV, and influenza during the 2025–2026 season.
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Upcoming Events
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Virtual: Register for Immunize.org Website Office Hours. Join a 30-minute discussion about our new Official Guidance: Healthcare Professional Organization Schedules content on February 11 at 4:00 p.m. (ET) or February 12 at 12:00 p.m. (ET). Recorded sessions archived.
To learn simple tips and tricks for using our websites efficiently, please register for our next set of Website Office Hours on Wednesday, February 11, at 4:00 p.m. (ET) ([link removed]) or Thursday, February 12, at 12:00 p.m. (ET) ([link removed]). The same content will be covered in both sessions.
We will open each 30-minute session with a short, live demonstration on navigating our new Official Guidance: Healthcare Professional Organization Schedules ([link removed]) website section. You can submit questions when you register or live on Zoom during the session.
Register today for Immunize.org Website Office Hours (content is the same for both):
* Wednesday, February 11, at 4:00 p.m. (ET) ([link removed])
* Thursday, February 12, at 12:00 p.m. (ET) ([link removed])
The archive of previous Website Office Hours content ([link removed]) is posted at Immunize.org’s "Webinars & Videos" page.
Mark your calendar ([link removed]) for future Immunize.org Website Office Hours.
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For more upcoming events, visit our Calendar of Events ([link removed]).
Editorial Information
Editor-in-Chief
Kelly L. Moore, MD, MPH
Managing Editor
John D. Gräbenstein, RPh, PhD
Associate Editor
Sharon G. Humiston, MD, MPH
Writer/Publication Coordinator
Taryn Chapman, MS
Courtnay Londo, MA
Style and Copy Editor
Marian Deegan, JD
Web Edition Managers
Arkady Shakhnovich
Jermaine Royes
Technical Reviewer
Kayla Ohlde
About IZ Express
Immunize.org welcomes redistribution of this issue of IZ Express or selected articles.
When you do so, please add a note that Immunize.org is the source of the material and provide a link to this issue ([link removed]).
IZ Express is supported in part by Grant No. NH23IP922654 from the National Center for Immunization and Respiratory Diseases, CDC. Its contents are solely the responsibility of Immunize.org and do not necessarily represent the official views of CDC.
IZ Express Disclaimer (http:// [link removed])
ISSN: 2771-8085
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