In this issue of Science for the People magazine, we seek critical analyses that trace the historical roots of our current public health crisis, highlight contemporary struggles to organize around public and environmental health, and question current public health structures, approaches, and ideologies. We invite pieces that examine the global political economy of public health, including how local ruling classes, right-wing governments, and transnational capital collaborate to dismantle public health systems and values. We also welcome analyses that illustrate alternative pathways to subvert the crises created by these systems, examining how support is being built by communities and collectives outside of crumbling and privatizing enterprises. As these dynamics affect communities worldwide, we aim to prioritize experiences, concerns, and case studies from the Global Majority. Crucially, although we recognize the critical inflection point brought about by the Trump administration’s most recent wave of attacks on public health, the response should not be a defense of the status quo as it had existed in the pre-Trump era of American soft power and reputation-laundering through imperial aid projects.