First, I would like to extend my best wishes to you for a happy and safe 2026. It's only the second day of the new year, but my heart is already filled with hope. No matter what we face, I'm confident that with you by our side, we'll continue to take steps forward in the fight against Alzheimer's disease.
Thank you for your interest in our fight. Our supporters are the reason we have been able to further our mission to lead the way to end Alzheimer's and all other dementia — by accelerating global research, driving risk reduction and early detection, and maximizing quality care and support.
As we step into 2026, I want to share some of the highlights from the past 12 months that our amazing and generous community of supporters helped make possible:
Advancing research. We currently have $450 million invested across more than 1,200 projects in 56 countries. Research efforts have led to the development of new tools and technology such as blood biomarker tests, which could help improve doctors' abilities to provide a more accurate diagnosis.
Uncovering new ways to lower our risk of developing Alzheimer's. Data from U.S. POINTER — an Association-led two-year clinical trial conducted to evaluate whether lifestyle interventions that simultaneously target many risk factors protect cognitive function in older adults who are at risk for cognitive decline — showed that positive actions can make a difference in brain health. The Association will use these promising study results to improve early detection efforts that are critical in qualifying for U.S. Food and Drug Administration-approved treatments.
Supporting people living with Alzheimer's or another dementia and care partners. We provided more than 10 million touches of care through our support resources including our free 24/7 Helpline (800.272.3900), alz.org, awareness presentations and more.
Strengthening advocacy efforts. The Association remains committed to ensuring Alzheimer's remains a national priority for lawmakers. We advocate for the passage of legislation that could greatly improve the health care system and quality of life for those impacted by Alzheimer's.
Our fight has never been more important. The number of Americans living with Alzheimer's is expected to climb from over 7 million to 13.8 million by 2060. This looming increase will have a direct financial impact on our country and create overwhelming strain for health care systems and families.
Our work is far from done, but with you by our side in the fight against Alzheimer's, we can continue to change the trajectory of this devastating disease.
Together, we'll make 2026 an amazing year. On behalf of all of us at the Alzheimer's Association, and our community, thank you so much for your dedication to our vision of a world without Alzheimer's and all other dementia.
With gratitude and best wishes for the new year,
Donna McCullough
Chief Operating Officer
Your donation will strengthen our efforts to advance Alzheimer's care, support and research. From face-to-face support to online education programs and promising global research initiatives, your gift makes a difference in the lives of all those affected by Alzheimer's and other dementias in your community and across the world. Thank you for your continued support.
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