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Issue 1,840: November 5, 2025
Top Stories
* Dozens of pertussis hospitalizations and two deaths in Louisiana; public health alerts lagged (#IZX1)
* Immunize​.org updates three print-ready QR code tables that give quick VIS access (#IZX2)
* National STEM/STEAM Day is November 8. Use Immunize.org and partner resources to help youth learn about vaccine science. (#IZX3)
* Measles 2025: 1,648 confirmed cases across 41 states; 5,109 confirmed and probable cases in Canada (#IZX4)
* “Which Adults Need Hepatitis B Vaccine?” Watch the 1-minute video, part of the Ask the Experts Video Series on YouTube. (#IZX5)
* Vaccines in the news (#IZX6)


Immunize​.org Website and Clinical Resources
* Spotlight on the website: "Vaccine Confidence & Addressing Concerns" (#IZX7)
* Summary: Updated Immunize.org clinical resources, web pages, webinars, and videos released in September and October (#IZX8)


Vaccine Information Statements
* Summary: These VIS translations were released during September and October (#IZX9)

Featured Resources
* Vaccinate Your Family announces Viraltruths.org website, providing plain language answers to the questions most frequently asked about vaccines (#IZX10)
* American Pharmacists Association releases interactive maps to help people find pharmacy-based vaccination locations (#IZX11)
* Pediatric Infectious Diseases Society offers “Comprehensive Vaccine Education Program—from Training to Practice,” a free education program to address vaccine misinformation and vaccine hesitancy (#IZX12)
* CHOP’s Vaccine Education Center releases two new videos in its Vaccines and Infectious Diseases in the News series, one on the HepB birth dose and one on separating MMR vaccine into three single-pathogen vaccines (#IZX13)
* CHOP’s Vaccine Education Center offers its new “Vaccine Dictionary” web page with short definitions of vaccine-related terminology (#IZX14)
* Explore the www.Give2MenACWY​.org website to increase coverage for the MenACWY booster and other adolescent vaccinations (#IZX15)


Notable Publications
* "Neurodevelopmental Outcomes of 3-Year-Old Children Exposed to Maternal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Utero" published in Obstetrics & Gynecology (#IZX16)


Global News
* "Diphtheria, a Once Vanquished Killer of Children, Is Resurgent" published in New York Times (#IZX17)


Upcoming Events
* Tomorrow; virtual: National Adult and Influenza Immunization Summit hosts webinar “Payment Challenges in the New Immunization Environment” on November 6 at 3:00 p.m. (ET) (#IZX18)
* Virtual: Register for Immunize​.org Website Office Hours. Join a 30-minute discussion about our new travel-vaccine content on November 12 at 4:00 p.m. (ET) or November 13 at 12:00 p.m. (ET). Recorded sessions archived. (#IZX19)


Editorial Information (#Editorial)
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Top Stories
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Dozens of pertussis hospitalizations and two deaths in Louisiana; public health alerts lagged

On May 1, the Louisiana Department of Health (LDH) issued a health alert to physicians ([link removed]) , warning of a sharp rise in pertussis cases that could result in a record high case count in 2025. By that time, LDH had identified 164 cases in the first 4 months of the year, including 42 hospitalizations ([link removed]) , surpassing the total number of annual cases reported in the state for at least 35 years. Louisiana recorded 153 cases in all of 2024. The most recent LDH news release on pertussis is dated May 14 ([link removed]) .
Two infants died of pertussis early in the year; 3 months elapsed after the second infant’s death until LDH issued a health alert to physicians and its first public statement ([link removed]) . Such a delay in notification is unusual. Prompt alerts from public health to physicians and the public when there is an outbreak of a serious vaccine-preventable disease are valuable to raise public awareness and motivate vaccinators to ensure the most vulnerable are protected.

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Nationally, CDC reports pertussis cases across the United States remain elevated this year ([link removed]) compared to immediately before the pandemic. As of September 20, 2025, 20,939 cases ([link removed]) of pertussis were reported in the United States. Of those, Louisiana reported 387 cases of pertussis ([link removed]) .

There are two simple and effective ways to prevent infant hospitalization and death from pertussis:
1. Administer a dose of Tdap between 27 and 36 weeks of gestation during every pregnancy. This step alone can reduce the risk of early infant hospitalization with pertussis by about 90%.
2. Vaccinate all infants against pertussis on time, beginning with the first DTaP at age 2 months, followed by the rest of the series at 4 months, 6 months, 15–18 months, and 4–6 years.

Pertussis infection does not result in lifelong immunity, and neither does pertussis vaccination. The risk of exposure to pertussis cannot be completely eliminated with the vaccines we have today. However, pertussis vaccination will prevent hospitalizations and save lives. Staying current on Tdap and DTaP vaccination is essential.

Related Links
* NPR: Louisiana Officials Waited Months to Warn Public of Whooping Cough Outbreak ([link removed]) (10/28/25)
* CDC: Pertussis Surveillance and Trends ([link removed]) web page
* Immunize​.org: Vaccines A–Z: Pertussis ([link removed]) main page

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Immunize​.org updates three print-ready QR code tables that give quick VIS access

Immunize​.org
updated three of its printable QR code tables for clinic use. The QR codes in these tables, when scanned (or clicked), link directly to a VIS. The document changes did not alter the VIS QR codes on the current documents, so there is no need to change the QR codes you are using now to continue accessing current VISs. The updates include:
* QR Code Links to Vaccine Information Statement (VIS) Translations: Influenza (Flu) Vaccine (Inactivated or Recombinant) ([link removed]) : A QR code for the new Pohnpeian influenza VIS translation was added
* QR Code Links to All Vaccine Information Statements (VISs) ([link removed]) : A QR code to the "Clinical Resources: VIS-Related Resources" main page was added
* QR Code Links to Routinely Recommended Vaccine Information Statements (VISs) ([link removed]) : A QR code to the "Clinical Resources: VIS-Related Resources" main page was added
* An outdated link to a Michigan-specific VIS website was removed from all three documents

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Related Links
* Immunize​.org: Clinical Resources: VIS-Related Resources ([link removed]) main page
* Immunize​.org: Clinical Resources A–Z ([link removed]) main page, where you can filter by topic, vaccine, language, or other criteria

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National STEM/STEAM Day is November 8. Use Immunize​.org and partner resources to help youth learn about vaccine science.

To observe National STEM/STEAM Day ([link removed]) on November 8, Immunize​.org compiled a list of educational resources on vaccines and the immune system. Share these credible resources for elementary, middle, and high school students.

For kindergarten students
* Daniel Tiger’s Neighborhood:
+ Helping Children Do Something New: Going to the Doctor ([link removed])
+ It’s Time for Daniel’s Shot ([link removed])
+ Why Do I Need to Get a Shot? ([link removed])
* Immunize​.org: Addressing Vaccination Anxiety for Infants and Toddlers: Strategies for Parents and Caregivers ([link removed]) (PDF)
* Vaccinate Your Family: Your Friends at the Zoo…Immunize by Two! ([link removed]) printable coloring book (PDF)

For elementary school children
* APhA: Super Heroes of COVID-19 Vaccination Coloring Book ([link removed]) (PDF)
* BrainPOP: Vaccines ([link removed])
* British Society for Immunology: Hands On Activities ([link removed])
* CHOP: Vaccine Resources for Kids and Teens ([link removed])
* Public Good Projects: Comic Book Series: How Immunization Protects Communities ([link removed])
* Vaccine Makers Project: Elementary School Lesson Plans ([link removed]) (3/7/18)
* Videos that share important lessons about vaccines, how they work, and important vaccine champions:
+ Peekaboo Kidz, The Dr Binocs Show: How Vaccines Work ([link removed]) (6:50 min.; 4/24/20)
+ SciShow Kids: Why Do We Get Vaccines? ([link removed]) (3:30 min.; 11/14/17)
+ TED-Ed: How Do Vaccines Work? ([link removed]) (4:35 min.; 1/12/15)

For middle school children
* Science Journal for Kids and Teens: 6 Scientific Articles About Vaccination ([link removed]) for middle and high school students
* UNICEF: Vaccine Education, for and with Youth ([link removed]) (4/29/24)
* Vaccine Makers Project: Middle School Lesson Plans ([link removed])
* Videos that share important lessons about vaccines, how they work, and important vaccine champions:
+ CDC: How Does Flu Make You Sick? ([link removed]) (57 seconds; 11/4/19)
+ Kurzgesagt—In a Nutshell: The Side Effects of Vaccines–How High Is the Risk? ([link removed]) (10:55 min.; 5/12/19)
+ TED-Ed Talk: How Do Vaccines Work? ([link removed]) (4:35 min.; 1/12/15)
+ Voices for Vaccines: Thomas Jefferson to Edward Jenner ([link removed]) (1:49 min.; 7/3/18)

For high school students
* History of Vaccines: Historyofvaccines.org ([link removed])
* Vaccine Makers Project: High School Lesson Plans ([link removed])
* Videos that share important lessons about vaccines, how they work, and important vaccine champions:
+ Kurzgesagt—In a Nutshell:
o The Side Effects of Vaccines—How High Is the Risk? ([link removed]) (10:55 min.; 5/12/19)
o The Coronavirus Explained and What You Should Do ([link removed]) (8:34 min.; 3/19/20)
o Measles Explained—Vaccinate or Not? ([link removed]) (5:33 min.; 2/24/15)
+ Science Journal for Kids and Teens: six scientific articles about vaccination for middle and high school students ([link removed])
+ Science News Explores: Explainer: What Is a Vaccine? ([link removed]) (7/18/17)
+ TED-Ed: How Do Vaccines Work? ([link removed]) (4:35 min.; 1/12/15)
+ Vaxopedia ([link removed]) website

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Measles 2025: 1,648 confirmed cases across 41 states; 5,109 confirmed and probable cases in Canada

As of October 28, CDC reported 1,648 confirmed measles cases ([link removed]) in 2025 in 41 states. Of reported confirmed cases, 87% were outbreak-associated. As of October 28:
* Utah reported 59 confirmed cases ([link removed]) , most related to the outbreak along its border with Arizona
* Arizona reported 97 confirmed cases ([link removed]) , most related to the outbreak along its border with Utah
* South Carolina reported 33 confirmed cases with 30 linked to an ongoing outbreak ([link removed]) in Spartanburg County

CDC’s count includes only laboratory-confirmed measles cases. Cases without laboratory testing for confirmation are not included. Actual measles cases for 2025 are, therefore, higher than confirmed case counts.

Canada is also experiencing a widespread measles outbreak ([link removed]) , with incidence rates that exceed those in the United States. October 26 marked a full year of continuous measles transmission in Canada. As a result of a year of uninterrupted measles transmission, Canada could soon lose its official designation as a nation that has eliminated measles. Canada reports 5,109 confirmed cases in 2025, through October 18. During week 42 (October 12–18), 19 new cases were reported.

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Case counts from Mexico lag, with September quarterly report numbers from the Pan American Health Organization ([link removed]) indicating more than 4,500 cases by September 9, 2025, with more than 4,200 of them concentrated in the Chihuahua state across the border from Texas. The Chihuahua outbreak is linked to imported cases exposed in the U.S. outbreak in Texas earlier in the year.

Immunize​.org offers measles-related resources for the public on several of our affiliated websites:
* VaccineInformation​.org: Measles ([link removed]) web page
* LetsGetRealAboutVaccines​.org: Measles ([link removed]) web page
* Immunize​.org: Vaccines A–Z: Measles ([link removed]) main page

Another credible source is the American Academy of Pediatrics’ Fact Checked: The Measles Vaccine Is Safe and Effective ([link removed]) web page.
Related Links
* CDC: Measles Cases and Outbreaks ([link removed]) main page
* CDC: Be Ready for Measles Toolkit ([link removed])
* Health Canada: Measles and Rubella Weekly Monitoring Report ([link removed])
* Johns Hopkins Bloomberg School of Public Health Center for Outbreak Response Innovation: Measles Outbreak Response ([link removed]) main page
* Immunize​.org: Vaccines A–Z: Measles ([link removed]) main page
* PAHO: Epidemiological Update Measles in the Americas Region September 19, 2025 ([link removed])

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“Which Adults Need Hepatitis B Vaccine?” Watch the 1-minute video, part of the Ask the Experts Video Series on YouTube.

This week, our featured episode from the Ask the Experts Video Series is titled Which Adults Need Hepatitis B Vaccine? ([link removed] ) Since 2022, the CDC and medical societies have recommended hepatitis B vaccination for all susceptible adults through age 59 years and continue to recommend vaccination of at-risk adults age 60 years and older. Catching up unvaccinated adults now is a simple step for a lifetime of protection.

The 1-minute video is available on our YouTube channel ([link removed]) , along with our full collection of quick video answers to popular Ask the Experts ([link removed]) questions.

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Like, follow, and share Immunize​.org’s social media accounts and encourage colleagues and others interested in vaccination to do likewise.
* Facebook at ImmunizeOrg ([link removed])
* Instagram at ImmunizeOrg ([link removed])
* LinkedIn at ImmunizeOrg ([link removed])
* YouTube at ImmunizeOrg ([link removed])

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Vaccines in the news

These recent articles convey the potential risks of vaccine-preventable diseases and the importance of vaccination.
* Gavi, The Vaccine Alliance: Six Reasons Why Community Health Workers Are the Unsung Heroes of Global Immunisation ([link removed]) (10/28/25)
* Washington Post: Vaccine Mistrust Is Hurting People. Two Pilots Decided to Act. ([link removed]) (10/28/25)
* KFF Health News: Doctors Muffled as Florida Moves to End Decades of Childhood Vaccination Mandates ([link removed]) (10/27/25)

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Immunize​.org Website and Clinical Resources
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Spotlight on the website: "Vaccine Confidence & Addressing Concerns"

This week, we spotlight Immunize​.org’s clinical resources for improving confidence and addressing concerns about vaccinations. "Vaccine Confidence & Addressing Concerns" is found under the Clinical Resources menu.

Each of the topics covered includes related resources available from Immunize​.org and our affiliated websites (VaccineInformation.org ([link removed]) and LetsGetRealAboutVaccines.org ([link removed]) ). Each topic also links to content from key partners.

Within each topic, the menu on the right side provides links to relevant sections on this page.

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Summary: Updated Immunize​.org clinical resources, web pages, webinars, and videos released in September and October

IZ Express regularly provides readers with information about Immunize​.org’s new and updated educational materials for healthcare professionals and handouts for patients. All Immunize​.org materials are free to distribute.  

In case you missed them during recent weeks, the following updated materials were posted for clinicians: 

2025–26 influenza season-related web page and materials: 
* Ask the Experts: Influenza ([link removed])  
* Standing Orders Templates for Administering Influenza Vaccine to Children and Teens ([link removed]) , and Adults ([link removed])  
* Screening Checklists for Contraindications to: 
+ Injectable Influenza Vaccine ([link removed]) , also available in Spanish ([link removed])  
+ Live Attenuated Intranasal Influenza Vaccination ([link removed]) , also available in Spanish ([link removed])  
* Influenza: Questions and Answers ([link removed])  
* Talking with Your Patient About Contraindications and Precautions to Influenza Vaccination ([link removed])  
* Communicating the Benefits of Influenza Vaccination ([link removed])  
* Guide for Determining the Number of Doses of Influenza Vaccine to Give to Children Age 6 Months Through 8 Years ([link removed])  
* How to Administer Intramuscular and Intranasal Influenza Vaccines ([link removed])  
* How to Administer Intranasal and Oral Vaccinations ([link removed])  
* Not Sure If You Can Get an Influenza Vaccine? ([link removed])  
* Don't Take Chances with Your Family's Health—Make Sure You All Get Vaccinated ([link removed])  
* Declination of Influenza Vaccination ([link removed])  

Other materials to support immunization and administration: 
* Healthcare Personnel Vaccination Recommendations ([link removed])
* Need Help Responding to Vaccine-Hesitant Parents? ([link removed])
* Meningococcal B Vaccine Recommendations by Age and Risk Factor ([link removed])  

Information and immunization schedules to share with patients:
* Reliable Sources of Immunization Information: Where Parents Can Go to Find Answers! ([link removed])
* Immunizations for Babies: A Guide for Parents ([link removed])
* Vaccinations for Infants and Children, Age 0–10 Years ([link removed])
* When Do Children and Teens Need Vaccinations? ([link removed])
* Vaccinations for Preteens and Teens ([link removed])
* You’re 16 . . . We Recommend These Vaccines for You! ([link removed])
* Vaccinations for Adults: You’re Never Too Old to Get Vaccinated! ([link removed])
* Vaccinations for Adults with Diabetes ([link removed])
* Vaccinations for Adults with Heart Disease ([link removed])
* Vaccinations for Adults with Lung Disease ([link removed])
* Vaccinations for Adults with Chronic Liver Disease or Infection ([link removed])
* Vaccinations for Adults with HIV Infection ([link removed])
* Vaccinations for Adults Without a Spleen ([link removed])
* Vaccinations for Men Who Have Sex with Men ([link removed])

Web pages: 
* Ask the Experts: RSV (Respiratory Syncytial Virus) ([link removed])  
* Ask the Experts: Zoster (Shingles) ([link removed])  
* Vaccine History Timeline ([link removed])  

Website Office Hours webinars:   
* Website Office Hours: Vaccine Information Statements (VIS) ([link removed])  (32:47)
* Website Office Hours: Clinical Resources ([link removed]) (37:48)

View the new collection of Immunize​.org website training videos, edited from the popular Office Hours series of webinars. David Sanders, MD, MS, is your guide through key content. The 12 videos can be the focus of training sessions (most under 15 minutes) to introduce staff and colleagues to the array of immunization resources available:
* Affiliated Websites ([link removed]) (19:42)
* Ask the Experts ([link removed]) (13:39)
* Clinical Resources ([link removed]) (16:12)
* Images, Webinars, Videos, & Social Media ([link removed]) (15:08)
* Let’s Get Real About Vaccines website ([link removed]) (20:44)
* News & Updates ([link removed]) (16:48)
* Official Guidance (State Resources ([link removed]) ) (11:37)
* Official Guidance, Part 1 (CDC, FDA, WHO) ([link removed]) (17:12)
* Publication Archives, Vaccine Timeline, & About Us ([link removed]) (13:29)
* Travel Vaccines, Vaccine Confidence, & Addressing Concerns ([link removed]) (11:32)
* Vaccine Information Statements (VISs) Website Section ([link removed]) (15:10)
* Vaccines A–Z ( ([link removed]) 14:42)

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Vaccine Information Statements
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Summary: These VIS translations were released during September and October

IZ Express regularly provides readers with information about VISs and translations of VISs. On May 29, 2025, CDC updated VISs for pneumococcal conjugate and polysaccharide vaccines (PCV and PPSV23). Immunize​.org recently posted new VIS translations in the following wide array of languages:
PPSV23 VIS ([link removed]) PCV VIS ([link removed])
Arabic ([link removed]) Arabic ([link removed])
Armenian ([link removed]) Armenian ([link removed])
Burmese ([link removed]) Bengali ([link removed])
Chinese-Simplified ([link removed]) Burmese ([link removed])
Chinese-Traditional ([link removed]) Chinese-Simplified ([link removed])
Farsi ([link removed]) Chinese-Traditional ([link removed])
French ([link removed]) Dari ([link removed])
Khmer ([link removed]) Farsi ([link removed])
Russian ([link removed]) French ([link removed])
Somali ([link removed]) German ([link removed])
Spanish PDF ([link removed]) , RTF ([link removed]) Haitian Creole ([link removed])
Tagalog ([link removed]) Hindi ([link removed])
Vietnamese ([link removed]) Italian ([link removed])
Japanese ([link removed])
Khmer ([link removed])
Korean ([link removed])
Pashto ([link removed])
Polish ([link removed])
Portuguese ([link removed])
Russian ([link removed])
Somali ([link removed])
Spanish PDF ([link removed]) , RTF ([link removed])
Swahili ([link removed])
Tagalog ([link removed])
Ukrainian ([link removed])
Urdu ([link removed])
Vietnamese ([link removed])
Yiddish ([link removed])

Families given any VIS translation should also receive the current official VIS, which is in English.

Check the version date of your inventory of VIS translations. Discard translations of previous versions as translations of current versions become available.

For additional support, view these resources from Immunize​.org:
* Clinical Resources: VIS-Related Resources ([link removed]) , PDFs
* Introducing VIS and VIS Translations ([link removed]) , video (3:53)
* Introducing VIS and VIS Translations (Mobile View) ([link removed]) , video (4:16)

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Featured Resources
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Vaccinate Your Family announces Viraltruths.org website, providing plain language answers to the questions most frequently asked about vaccines

Vaccinate Your Family (VYF) launched its new microsite Viraltruths.org ([link removed]) built to provide plain language answers to the questions most frequently asked about vaccines. The site serves as a helpful tool to understand the challenging, dynamic vaccine policy and information environment.

The site features:
* Resources ([link removed]) you can use and distribute to combat misinformation
* Vaccine Intelligence Report ([link removed]) , a weekly newsletter of vaccine policy updates
* Share your vaccine access challenges story ([link removed]) submission page

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American Pharmacists Association releases interactive maps to help people find pharmacy-based vaccination locations

The American Pharmacists Association (APhA) offers two interactive maps that can be used to find pharmacy vaccination locations:
* Public map of vaccine access ([link removed]) allows searches by address or zip code to identify pharmacy vaccination locations. Filters allow tailored searches based on handicap access, walk-in basis, and languages spoken. Map pin descriptions give hours of vaccine availability for each pharmacy.
* Provider map of vaccine access ([link removed]) allows searches to identify vaccine access, with the ability to filter for medically underserved areas, social vulnerability index, health professional shortage area, and pharmacy proximity.

[link removed]

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Pediatric Infectious Diseases Society offers “Comprehensive Vaccine Education Program—from Training to Practice,” a free education program to address vaccine misinformation and vaccine hesitancy

The Pediatric Infectious Diseases Society (PIDS) offers a free educational program, Comprehensive Vaccine Education Program—from Training to Practice ([link removed]) , to help combat vaccine misinformation and address hesitancy in two ways:
* Collaboration for Vaccine Education and Research ([link removed]) (CoVER) curriculum: Enhancing vaccine knowledge and confidence in having discussions with patients and parents through a web-based educational curriculum. The CoVER curriculum consists of 19 online modules.
* Vaccine Education from Training to Practice Program: Enhancing access for medical providers to reliable, up-to-date and accurate vaccine information through The Vaccine Handbook ([link removed]) (PDF).

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CHOP’s Vaccine Education Center releases two new videos in its Vaccines and Infectious Diseases in the News series, one on the HepB birth dose and one on separating MMR vaccine into three single-pathogen vaccines

Children's Hospital of Philadelphia's (CHOP) Vaccine Education Center released two new videos in its Vaccines and Infectious Diseases in the News ([link removed]) series featuring Paul A. Offit, MD:
* Hepatitis B Vaccine Birth Dose ([link removed])
* Does Splitting MMR into 3 Vaccines Serve Public Health? ([link removed])

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Resources accompany each video, available on the Vaccines and Infectious Diseases in the News ([link removed]) web page.
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CHOP’s Vaccine Education Center offers its new “Vaccine Dictionary” web page with short definitions of vaccine-related terminology

Children's Hospital of Philadelphia's (CHOP) Vaccine Education Center is offering a new vaccine dictionary ([link removed]) resource for the public. It gives short definitions of relevant terms and, in some cases, links for those who want to take a deeper dive. The dictionary also defines common vaccine-associated acronyms.

[link removed]

If there is a term that should be added, please contact Parents PACK ([link removed]) .
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Explore the www.Give2MenACWY​.org website to increase coverage for the MenACWY booster and other adolescent vaccinations

Immunize​.org's www.Give2MenACWY.org ([link removed]) website promotes the importance of adolescent vaccination, including the recommended MenACWY vaccine booster dose at age 16. Many teens are behind on vaccines, so vaccine outreach is more important than ever.

Materials on this colorful website for healthcare professionals incorporate the 2020 ACIP meningococcal vaccine recommendations ([link removed]) and coverage statistics from CDC’s National Immunization Survey–Teen (NIS–Teen). One particularly popular resource on the site is the Algorithm for MenACWY Immunization in Adolescents 11 Through 18 Years of Age ([link removed]) .

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The website is divided into five easy-to-access sections:
* Vaccinate Teens ([link removed]) : teen vaccination schedules and tips for improving vaccination rates
* Give 2 Doses ([link removed]) : tools to help improve second dose coverage of MenACWY vaccine
* 16-Year-Old Visit ([link removed]) : resources to help providers and patients remember the important vaccines recommended for 16-year-olds
* Tools for Providers ([link removed]) : tools to explain meningococcal ACWY vaccine recommendations and improve coverage for all adolescent vaccines
* Resources ([link removed]) : links to print materials ([link removed]) , organizations ([link removed]) involved in adolescent vaccination, personal stories ([link removed]) about the importance of vaccination, and otherresources ([link removed]) of interest

The site also categorizes materials ([link removed]) according to whether they are primarily of interest to providers, to adolescents, or to parents.

Visit Give2MenACWY.org ([link removed]) and enjoy browsing (and deploying) its bountiful resources.

Related Links
* MenACWY: You're Not Done If You Give Just One: Give 2 Doses to Strengthen Protection ([link removed])
* Recommending MenACWY: What to Say and How to Say It ([link removed])
* Top 10 Ways to Improve Adolescent Immunization Rates ([link removed])
* Developing an Immunization Culture in Your Office ([link removed])
* Know Your Rates: Measuring Immunization Success in Your Practice ([link removed])
* You're 16: We Recommend These Vaccines for You ([link removed])
* Dear Colleague Letter: 16-Year-Old Patients: Make Sure They Receive Their Annual Well Visit and Vaccinations ([link removed]) , signed by six medical societies
* Ask the Experts: Meningococcal ACWY ([link removed])
* CDC: ACIP Meningococcal Vaccine Recommendations ([link removed])
* CDC: Vaccination Coverage Among Adolescents Aged 13–17 Years—National Immunization Survey–Teen, United States, 2024 ([link removed] )

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Notable Publications
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"Neurodevelopmental Outcomes of 3-Year-Old Children Exposed to Maternal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Utero" published in Obstetrics & Gynecology

In the October 30 issue, Obstetrics & Gynecology published Neurodevelopmental Outcomes of 3-Year-Old Children Exposed to Maternal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Utero ([link removed]) . The study found that infection during pregnancy with COVID-19 virus increased the risk of neurodevelopmental disorders in offspring by the third birthday. Portions of the abstract appear below.

To determine whether in utero exposure to maternal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is associated with increased risk of adverse neurodevelopmental outcomes in children by age 3 years. . . .

We conducted a retrospective cohort study of 18,124 live births to individuals who delivered between March 1, 2020, and May 31, 2021, within the Mass General Brigham health system. The exposure of interest was
maternal SARS-CoV-2 infection, defined as a positive SARS-CoV-2 polymerase chain reaction test result during pregnancy. . . .

Maternal SARS-CoV-2 infection in pregnancy was associated with increased risk of adverse neurodevelopmental diagnoses by age 3 years, with effects most pronounced after third-trimester exposure and in male offspring. These findings highlight the importance of long-term neurodevelopmental monitoring for SARS-CoV-2–exposed children.
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Global News
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"Diphtheria, a Once Vanquished Killer of Children, Is Resurgent" published in New York Times

On October 27, New York Times published Diphtheria, a Once Vanquished Killer of Children, Is Resurgent ([link removed]) . Portions of the article appear below.
There are large diphtheria outbreaks now in Somalia, Sudan, Yemen and Chad—countries with civil wars or large populations of refugees where vaccination coverage is low, surveillance is weak and frail health systems leave children undiagnosed or treated too late. . . .

Diphtheria was once a major killer of children in the United States and other industrialized countries, but cases began to drop with the introduction of a diphtheria vaccine in the 1940s, and by the 1970s, the disease had become rare. There was just one case a year reported in the United States in the two decades after 1996, and only a handful since.

The disease was vanishing from developing countries, too, at the beginning of the 21st century. But cases began to resurge about 15 years ago. Venezuela had a major outbreak, when its once-strong public health system fell apart during years of political instability. Bangladesh had one, beginning in 2017, mostly among Rohingya refugees packed into crowded camps. There have been nearly 30,000 reported cases in Nigeria in the last two years, mostly in the country’s north, where vaccination coverage is lower.

There have also been cases in Europe in recent years, usually among young people who emigrated from Syria or Afghanistan and were not immunized.

In the United States, the few cases have been associated with travelers. However American vaccination rates have declined slowly but steadily ([link removed]) for the last five years; 92 percent of kindergarten students nationally had full coverage with diphtheria vaccination in the 2024–25 school year, down from 95 percent in 2020. Achieving broad immunity requires at least 85 percent coverage.
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Upcoming Events
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Tomorrow; virtual: National Adult and Influenza Immunization Summit hosts webinar “Payment Challenges in the New Immunization Environment” on November 6 at 3:00 p.m. (ET)

The National Adult and Influenza Immunization Summit (NAIIS) will host an open, free webinar titled Payment Challenges in the New Immunization Environment ([link removed]) at 3:00 p.m. (ET) on November 6. Speakers include Kate Berry, MPP, America's Health Insurance Plans; Chelsea Cipriano, MPH, Common Health Coalition; Mitchell Finkel, Avalere Health; Dan Jones, Alliance of Community Health Plans; and Sarah Price, MSN-ED, National Association of Community Health Centers.

Register for the webinar ([link removed]) .
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Virtual: Register for Immunize​.org Website Office Hours. Join a 30-minute discussion about our new travel-vaccine content on November 12 at 4:00 p.m. (ET) or November 13 at 12:00 p.m. (ET). Recorded sessions archived.

To learn simple tips and tricks for using our websites efficiently, please register for our next set of Website Office Hours on Wednesday, November 12, at 4:00 p.m. (ET) ([link removed]) or Thursday, November 13, at 12:00 p.m. (ET) ([link removed]) . The same content will be covered in both sessions.

[link removed]

We will open each 30-minute session with a short, live demonstration on navigating our Travel Vaccines website sections on Immunize​.org and VaccineInformation​.org. You can submit questions when you register or live on Zoom during the session.

Register today for Immunize​.org Website Office Hours (content is the same for both):
* Wednesday, November 12, at 4:00 p.m. (ET) ([link removed])  
* Thursday, November 13, at 12:00 p.m. (ET) ([link removed])

The archive of previous Website Office Hours content ([link removed]) is posted at Immunize​.org’s "Webinars & Videos" page.

Mark your calendar ([link removed]) for future Immunize​.org Website Office Hours.
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For more upcoming events, visit our Calendar of Events ([link removed]) .
Editorial Information
Editor-in-Chief
Kelly L. Moore, MD, MPH
Managing Editor
John D. Gr
äbenstein, RPh, PhD
Associate Editor
Sharon G. Humiston, MD, MPH
Writer/Publication Coordinator
Taryn Chapman, MS
Courtnay Londo, MA
Style and Copy Editor
Marian Deegan, JD
Web Edition Managers
Arkady Shakhnovich
Jermaine Royes
Contributing Writer
Laurel H. Wood, MPA
Technical Reviewer
Kayla Ohlde

About IZ Express
Immunize​.org welcomes redistribution of this issue of IZ Express or selected articles.
When you do so, please add a note that Immunize​.org is the source of the material and provide a link to this issue ([link removed]) .

IZ Express is supported in part by Grant No. NH23IP922654 from the National Center for Immunization and Respiratory Diseases, CDC. Its contents are solely the responsibility of Immunize​.org and do not necessarily represent the official views of CDC.

IZ Express Disclaimer (http:// [link removed])
ISSN: 2771-8085

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