World Alzheimer's Day is Tomorrow! Last Chance to Double Your Impact.
We're down to one day left until World Alzheimer's Day — when our World Alzheimer's Day 2X Match Challenge ends. We only have until midnight tomorrow — September 21 — to reach our goal. That's why we urgently need your support. Your gift today could be the one to unlock these critically needed match funds that will advance research for treatment breakthroughs, as well as help provide care and support to the millions impacted by Alzheimer's disease or another dementia.
Double Your Impact in the Fight with a Gift by Midnight Tomorrow.
This World Alzheimer's Day, you have the chance to be part of something big. Something global. Something that can change lives and offer hope to generations to come. Thanks to our generous supporter, Leone McKay, any gift you make — up to a total of $150,000 — can have double the impact. Her pledge is made in honor of her late husband, Col. William P. McKay, whom she lost to Alzheimer's disease, and will support vital research. Your gift can go 2X as far toward advancing research and helping to provide care and support. We only have until midnight tomorrow, and we urgently need you to stand with us at this critical time. Will you make your first gift today that can go 2X as far in the fight to end Alzheimer's?
We're excited to report that results from U.S. POINTER — a two-year clinical trial to evaluate whether lifestyle interventions that simultaneously target many risk factors protect cognitive function in older adults who are at risk for cognitive decline — were presented at the 2025 Alzheimer's Association International Conference® (AAIC®), and the findings give us hope.
About the study:
2,111 older adults were enrolled in the study from five different regions across the country. More than 30% of participants were from groups that have been historically underrepresented in dementia research.
Participants were randomly assigned to either a self-guided or structured lifestyle program. Both interventions focused on increasing physical activity, improving nutrition, cognitive and social challenge and health monitoring — but differed in structure, accountability and support provided.
Results:
Cognitive function improved from baseline over the two years for both intervention groups, but the improvement was greater for the structured group. This extra benefit was similar across all subgroups of U.S. POINTER participants.
The positive results of U.S. POINTER encourage us to look at the potential for a combination of a lifestyle program and drug treatment as the next frontier in our fight against cognitive decline and dementia.
Healthy Habits for Your Brain
Here are just a few positive, everyday actions that could make a difference in lowering the risk of cognitive decline and possibly Alzheimer's and dementia. With a gift that can double in impact during our World Alzheimer's Day 2X Match Challenge, you can help make more educational resources like our 10 Healthy Habits for Your Brain available, as well as accelerate research and help provide care and support to millions impacted by Alzheimer's.
Your Gift Can Go 2X As Far in Honor of Someone You Love This World Alzheimer's Day.
This World Alzheimer's Day, and every day, we honor and cherish those we have lost to this disease. With a tribute gift today, you can leave a lasting legacy for a loved one and help further our mission to lead the way to end Alzheimer's and all other dementia — by accelerating global research, driving risk reduction and early detection, and maximizing quality care and support.
Your donation will strengthen our efforts to advance Alzheimer's care, support and research. From face-to-face support to online education programs and promising global research initiatives, your gift makes a difference in the lives of all those affected by Alzheimer's and other dementias in your community and across the world. Thank you for your continued support.
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