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IZ Express #1,827: School-entry vaccination coverage drops again, clesrovimab recommendations accepted, and more
| From | Immunize.org <[email protected]> |
| Subject | IZ Express #1,827: School-entry vaccination coverage drops again, clesrovimab recommendations accepted, and more |
| Date | August 13, 2025 10:01 AM |
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Issue 1,827: August 13, 2025
Top Stories
* CDC data show vaccination coverage drops and exemptions rise (again) among kindergarteners for the 2024–25 school year (#IZX1)
* All pending ACIP recommendations from June meeting are now official: clesrovimab for RSV prevention and universal seasonal influenza vaccination (#IZX2)
* Immunize.org issues updated standing orders template for RSV vaccination of older adults to include high-risk adults age 50 through 74 years (#IZX3)
* Immunize.org updates “Standing Orders for Administering Recombinant Zoster Vaccine (Shingrix) to Adults” template to include manufacturer-filled syringe option (#IZX4)
* Immunize.org posts “Influenza Vaccine Products for the 2025–2026 Influenza Season” (#IZX5)
* Immunize.org updates "Checklist of Current Versions of U.S. COVID-19 Vaccination Guidance and Clinic Support Tools" (#IZX6)
* Watch CDC’s COCA webinar “Clinician Update on Measles Cases and Outbreaks in the United States” on August 14 at 2:00 p.m. (ET); CE credit offered (#IZX7)
* Immunize.org remembers our friend, Dr. Larry Pickering, shaper of U.S. vaccination policy (#IZX8)
* Immunize.org’s Hepatitis B Birth Dose Honor Roll recognizes 590 institutions, including one new honoree (#IZX9)
* Which pneumococcal vaccine is due for an 80-year-old who received a dose of PPSV23 at 65? Watch the 2-minute answer, part of the Ask the Experts Video Series on YouTube. (#IZX10)
* Vaccines in the news (#IZX11)
Immunize.org Website and Clinical Resources
* Spotlight on the website: LetsGetRealAboutVaccines.org: “Learn About Children’s Vaccines” (#IZX12)
* Summary: Updated Immunize.org clinical resources released in June and July (#IZX13)
Featured Resources
* Migration Health Initiative offers hepatitis B resources for those serving sub-Saharan African and Asian immigrant communities in the United States (#IZX14)
* It’s National Immunization Awareness Month! Use these resources to encourage vaccination. (#IZX15)
Notable Publications
* “Emergency Department Survey of Vaccination Knowledge, Vaccination Coverage, and Willingness to Receive Vaccines in an Emergency Department Among Underserved Populations—Eight U.S. Cities, April–December, 2024” published in MMWR (#IZX16)
* Journal of Adolescent Health publishes supplement on adolescent well visits and vaccination (#IZX17)
* “Safety of JN.1-Updated mRNA COVID-19 Vaccines” published in JAMA (#IZX18)
Upcoming Events
* Virtual: North Dakota State University Center for Immunization Research and Education hosts webinar titled “The Role of Vaccines in Eradicating and Eliminating Diseases” on August 18 at 1:00 p.m. (ET); CE credit offered (#IZX19)
* Virtual: Migration Health Initiative offers webinar titled “Practical Approaches to Adult-Dose Hepatitis B Vaccine Promotion in Newcomer Communities” on August 20 at 1:00 p.m. (ET) (#IZX20)
* Register for Immunize.org Website Office Hours. Ask questions and learn about the VIS web section on September 10 at 4:00 p.m. (ET) or September 11 at 12:00 p.m. (ET). Recorded sessions archived. (#IZX21)
Editorial Information (#Editorial)
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Top Stories
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CDC data show vaccination coverage drops and exemptions rise (again) among kindergarteners for the 2024–25 school year
On July 31, CDC released U.S. data ([link removed]) on vaccination coverage and exemptions from the 2024–25 school year. Vaccination coverage among kindergartners declined for all reported vaccines from the year before, from 92.1% for DTaP to 92.5% for MMR and polio vaccine. These national numbers mask wide variability of coverage rates. For example: In Idaho, 21.5% of kindergarten students lacked documentation of at least two doses of MMR, while just 1.8% lacked 2-dose documentation in Connecticut. Coverage for MMR, DTaP, polio vaccine, and varicella vaccine decreased in more than half of states. Nationwide, about 286,000 kindergartners had no documentation of completing the MMR series.
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For the 2024–25 school year, exemptions among kindergarteners for one or more vaccines increased from 3.3% in the 2023–24 school year to 3.6%. Exemptions increased in 36 states and the District of Columbia, with 17 states reporting exemption incidence exceeding 5%. About 138,000 kindergarteners were exempted from one or more vaccination requirements.
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Related Links
* CDC: Vaccination Coverage and Exemptions among Kindergartners ([link removed]) web page
* Immunize.org: Official Guidance: State Policies ([link removed]) main page
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All pending ACIP recommendations from June meeting are now official: clesrovimab for RSV prevention and universal seasonal influenza vaccination
On August 4, the CDC Director accepted the June 25–26 ACIP recommendation ([link removed]) that the RSV preventive antibody clesrovimab (Enflonsia, Merck) be added as an option for protection of infants younger than age 8 months born during or entering their first RSV season. There is no preference between nirsevimab (Beyfortus, Sanofi) and clesrovimab for eligible infants. Only nirsevimab is licensed and recommended for older infants and toddlers at high risk who are entering their second RSV season. This is now an official CDC recommendation.
On August 4, CDC updated the ACIP Recommendations ([link removed]) web page to show that on July 22, the HHS Secretary accepted the June ACIP recommendation for routine annual influenza vaccination of all people age 6 months and older who do not have contraindications. This notice was added to the Secretary’s previously listed July 22 acceptance of the ACIP recommendation ([link removed]) to use 2025–26 seasonal influenza vaccines that do not contain thimerosal as a preservative.
All recommendations ([link removed]) from the June 25–26 ACIP meeting have now been accepted. Immunize.org is in the process of updating its materials to reflect these new official recommendations.
Related Links
* CDC: ACIP Recommendations ([link removed]) web page
* Immunize.org: News and Updates: Official Release Repository ([link removed]) main page
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Immunize.org issues updated standing orders template for RSV vaccination of older adults to include high-risk adults age 50 through 74 years
Immunize.org updated its Standing Orders for Administering Respiratory Syncytial Virus Vaccine (RSV) to Adults Age 50 Years and Older ([link removed]) template to reflect the recommendation, adopted in June 2025, expanding the vaccination recommendation for adults at high risk from age 60 through 74 to age 50 through 74. The optimal time to be vaccinated begins in August before the typical fall RSV season begins, although vaccination may occur at any time of year, if needed. At this time, revaccination of previously vaccinated people is not recommended. Meaningful RSV protection lasts at least 2 years, and possibly longer. All unvaccinated adults age 75 years or older are also recommended to receive an RSV vaccine. All eligible adults may receive any one of the three licensed vaccines:
* Abrysvo, Pfizer
* Arexvy, GSK
* mResvia, Moderna
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Related Links
* Immunize.org: Clinical Resources: Standing Orders Templates ([link removed]) main page
* Immunize.org: Vaccines A–Z: RSV (Respiratory Syncytial Virus) ([link removed]) main page
* Immunize.org: Clinical Resources A–Z ([link removed]) main page, where you can filter by topic, vaccine, language, or other criteria
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Immunize.org updates “Standing Orders for Administering Recombinant Zoster Vaccine (Shingrix) to Adults” template to include manufacturer-filled syringe option
Immunize.org updated its Standing Orders for Administering Recombinant Zoster Vaccine (Shingrix) to Adults ([link removed]) template to include availability of new Shingrix (GSK) packaging. Now, in addition to the 2-vial package that requires reconstitution, there is a manufacturer-filled syringe option that does not require reconstitution.
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Related Links
* Immunize.org: Clinical Resources: Standing Orders Templates ([link removed]) main page
* Immunize.org: Vaccines A–Z: Zoster (Shingles) ([link removed]) web page
* Immunize.org: Clinical Resources A–Z ([link removed]) main page, where you can filter by topic, vaccine, language, or other criteria
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Immunize.org posts “Influenza Vaccine Products for the 2025–2026 Influenza Season”
Immunize.org posted Influenza Vaccine Products for the 2025–2026 Influenza Season ([link removed]) , our popular 1-page reference document, to list all products available for the 2025–26 influenza season. A new note addresses the ACIP recommendation ([link removed]) to use 2025–26 seasonal influenza vaccine packages that do not contain thimerosal as a preservative; availability of preservative-containing multidose vials is expected to vary by manufacturer.
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Related Links
* Immunize.org: Vaccines A–Z: Influenza ([link removed]) web page
* Immunize.org: Clinical Resources A–Z ([link removed]) main page, where you can filter by topic, vaccine, language, or other criteria
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Immunize.org updates "Checklist of Current Versions of U.S. COVID-19 Vaccination Guidance and Clinic Support Tools"
Immunize.org published the August 7 version of its Checklist of Current Versions of U.S. COVID-19 Vaccination Guidance and Clinic Support Tools ([link removed]) . This resource checklist is updated when significant changes are made to COVID-19 vaccine resources.
The August 7 version includes revised links to updated 2024–25 Formula COVID-19 vaccine fact sheets and package inserts reflecting:
* Updated labeling of mRNA vaccines to include safety information about the rare risk of myocarditis and pericarditis following vaccination
* Revised indications for COVID-19 vaccines based on age and presence of high-risk conditions
* Addition of new package inserts for mNexspike (Moderna) and Nuvaxovid (Novavax), licensed by FDA in recent weeks (these vaccines currently are not available)
Several CDC resources were removed from the checklist (e.g., the 2024–25 recommended COVID-19 immunization schedule and vaccine At-a-Glance sheets) because CDC removed them from its website. Resources for the 2025–26 season, including new Immunize.org standing orders templates for 2025–2026 Formula COVID-19 vaccines, will be added as they become available.
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The resource checklist is updated when significant new COVID-19 vaccine resources are released. The date of the current version of the checklist appears within the footer. All who offer COVID-19 vaccination should review reference materials in use and replace as needed with the most current versions.
Related Links
* CDC: U.S. COVID-19 Vaccine Product Information ([link removed]) main page
* CDC: Interim Clinical Considerations ([link removed]) main page for use of COVID-19 vaccines
* Immunize.org: Vaccines A–Z: COVID-19 ([link removed]) main page
* Immunize.org: Clinical Resources A–Z ([link removed]) main page, where you can filter by topic, vaccine, language, or other criteria
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Watch CDC’s COCA webinar “Clinician Update on Measles Cases and Outbreaks in the United States” on August 14 at 2:00 p.m. (ET); CE credit offered
CDC will host a Clinician Outreach and Communication Activity (COCA) call titled Clinician Update on Measles Cases and Outbreaks in the United States ([link removed]) at 2:00 p.m. (ET) on August 14. Presenters will discuss the current epidemiology of measles in the United States and address common clinical questions about preventing, identifying, and testing for measles. Presenters will also summarize MMR vaccination recommendations and considerations.
A recording of the COCA presentation will be archived on the COCA Calls web page ([link removed]) .
Free CE credit (including CME, CPE, and CNE) will be offered for this COCA call.
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As of August 6, CDC reported 1,356 confirmed measles cases ([link removed]) in 2025 in 40 states, including the first cases reported this year in Wisconsin.
CDC only requires reporting of laboratory-confirmed measles cases. Cases without laboratory testing for confirmation are not included in these numbers. Actual numbers of cases are, therefore, higher than confirmed case counts.
A map of 2025 measles cases ([link removed]) in the contiguous United States, as of August 4, from the Johns Hopkins International Vaccine Access Center ([link removed]) , appears below. The U.S. Measles Tracker ([link removed]) website includes state and county-level data.
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Related Links
* CDC: Measles Cases and Outbreaks ([link removed]) main page
* CDC: Be Ready for Measles Toolkit ([link removed])
* AAP: How to Protect Your Children During a Measles Outbreak ([link removed]) web page
* Johns Hopkins Bloomberg School of Public Health Center for Outbreak Response Innovation: Measles Outbreak Response ([link removed]) main page
* Immunize.org: Vaccines A–Z: Measles ([link removed]) main page
* Immunize.org: Ask the Experts: MMR (Measles, Mumps, and Rubella) ([link removed]) web page
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Immunize.org remembers our friend, Dr. Larry Pickering, shaper of U.S. vaccination policy
Larry K. Pickering, MD, FAAP, who served as executive secretary of the ACIP from 2005 to 2015, died at age 81 on July 1.
Dr. Pickering served on the National Vaccine Advisory Committee from 2017 to 2020 and was senior adviser to the director of the CDC’s National Center for Immunization and Respiratory Diseases. Dr. Pickering edited the American Academy of Pediatrics’ Red Book: Report of the Committee on Infectious Diseases editions published in 2000, 2003, 2006, 2009, and 2012. He was an associate editor of the 1994 and 1997 editions. For more on Dr. Pickering’s remarkable dedication to the health of children, see the article in AAP News ([link removed]) .
A memorial service will be held in September 2025 to honor his enduring legacy in pediatric infectious disease and public health. For more information, please see his obituary ([link removed]) .
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Immunize.org’s Hepatitis B Birth Dose Honor Roll recognizes 590 institutions, including one new honoree
Immunize.org is pleased to welcome one new institution into its Hepatitis B Birth Dose Honor Roll ([link removed](healthcare) ) , which now recognizes 590 honorees. The new birthing institution appears below with its reported hepatitis B birth dose coverage rates in parentheses.
* Hazard ARH Regional Medical Center, Hazard, KY (95%)
Please join us in recognizing these honorees with sustained excellence that qualify for an additional year:
* Capital Health Medical Center – Hopewell, Pennington, NJ (91%) (5 years)
* Elmhurst Hospital, Elmhurst, IL (91%) (5 years)
* Lawrence General Hospital, Lawrence, MA (97%) (6 years)
The Honor Roll includes birthing institutions from 50 states, the District of Columbia, American Samoa, Guam, Puerto Rico, Northern Mariana Islands, and U.S. military hospitals overseas.
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The Honor Roll is a key part of Immunize.org’s initiative urging the nation’s hospitals to Give Birth to the End of Hep B ([link removed]) . Hospitals and birthing centers are recognized for attaining high coverage for hepatitis B vaccine at birth and meeting additional criteria. The How to Apply ([link removed]) web page provides information on the criteria for inclusion in the Hepatitis B Birth Dose Honor Role and the application form.
Honorees receive an 8.5" x 11" color certificate suitable for printing and framing. Their acceptance is announced through Immunize.org’s social media channels and to IZ Express’s readers.
Please visit the Hepatitis B Birth Dose Honor Roll web page that lists these institutions and celebrates their vigorous efforts to protect infants from perinatal hepatitis B transmission.
Related Immunize.org Resources
* Give Birth to the End of Hep B ([link removed]) main page
* Hepatitis B Birth Dose Honor Roll ([link removed](healthcare)) web page
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Which pneumococcal vaccine is due for an 80-year-old who received a dose of PPSV23 at 65? Watch the 2-minute answer, part of the Ask the Experts Video Series on YouTube.
This week, our featured episode from the Ask the Experts Video Series addresses the current pneumococcal vaccination options for an 80-year-old who received a dose of PPSV23 at age 65 ([link removed]) . The video briefly explains the reasoning behind giving one dose of PCV20 or one dose of PCV21, but no additional dose of PPSV23.
The 2-minute video is available on our YouTube channel ([link removed]) , along with our full collection of quick video answers to popular Ask the Experts ([link removed]) questions.
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Like, follow, and share Immunize.org’s social media accounts and encourage colleagues and others interested in vaccination to do likewise.
* Facebook at ImmunizeOrg ([link removed])
* Instagram at ImmunizeOrg ([link removed])
* LinkedIn at ImmunizeOrg ([link removed])
* YouTube at ImmunizeOrg ([link removed])
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Vaccines in the news
These recent articles convey the potential risks of vaccine-preventable diseases and the importance of vaccination.
* Gavi, The Vaccine Alliance: Vaccine Hesitancy: How Social and Technological Issues Converged to Spawn Mistrust ([link removed]) (8/6/25)
* Guardian: COVID Cases Rising in US as Officials Plan to Restrict Booster Vaccines ([link removed]) (8/525)
* Contemporary Pediatrics: Aligning Vaccinations with the Start of a New School Year ([link removed]) (8/4/25)
* CIDRAP: KFF Poll Shows Most Americans Plan to Skip Fall COVID Booster ([link removed]) (8/4/25)
* CNN: HHS Further Constrains Certain Vaccine Advisers to the CDC, Limiting Their Input in Evidence Reviews ([link removed]) (8/1/25)
* Medpage Today: Vaccine Expert: My Grandchild Has Autism, but Vaccines Aren't to Blame ([link removed]) [commentary from Immunize.org board member Kathryn M. Edwards, MD] (7/31/25)
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Immunize.org Website and Clinical Resources
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Spotlight on the website: LetsGetRealAboutVaccines.org: "Learn About Children’s Vaccines"
Our newest website, Let’sGetRealAboutVaccines.org, is a trustworthy, parent-friendly platform that delivers factual vaccine guidance. It equips both families and providers with tools to advocate for childhood vaccination confidently.
This week we spotlight the Learn About Children’s Vaccines ([link removed]) section of this website. Found under the first menu tab, this section offers clear information to help families separate fact from fiction and to learn why most parents make sure their children receive vaccines.
The main page summarizes the protection childhood vaccines offer and provides links to additional information. Five additional pages are available from this page and from the menu:
* Vaccine-Preventable Diseases ([link removed]) : Details about illnesses that vaccines help prevent, grouped by age category. This includes information about vaccine effectiveness and possible side effects.
* Vaccine Safety ([link removed]) : Insights into how vaccines are developed and evaluated for safety. This subsection explains safety reporting.
* Vaccine Science ([link removed]) : Explanations of how the human immune system and vaccines work.
* Vaccination Schedule ([link removed]) : Guidance on when children should receive specific vaccines and how the vaccine schedule is developed.
* Common Questions ([link removed]) : Answers to parents’ frequently asked questions.
We hope you find this section of LetsGetRealAboutVaccines.org useful. Please share these links with anyone looking for credible, unbiased information about childhood vaccines.
To learn simple tips and tricks for using the website efficiently, view the archived Website Office Hours: Let's Get Real About Vaccines website ([link removed] ) webinar for more information.
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Summary: Updated Immunize.org clinical resources released in June and July
IZ Express regularly provides readers with information about Immunize.org’s new and updated educational materials for healthcare professionals and handouts for patients. All Immunize.org materials are free to distribute.
In case you missed them during recent weeks, the following new and updated materials were posted:
Immunize.org Materials for Clinicians
Standing Orders Templates for Administering:
* Meningococcal ACWY Vaccine to Adults ([link removed])
* Meningococcal ACWY Vaccine to Children and Teens ([link removed])
Materials Supporting Immunization Services:
* Administering Vaccines: Dose, Route, Site, and Needle Size ([link removed])
* Vaccine Administration Record for Adults ([link removed])
* Vaccine Administration Record for Children and Teens ([link removed])
* Notification of Immunization Letter Template ([link removed])
Immunize.org Webinars:
* Website Office Hours: News & Updates ([link removed])
* Website Office Hours: Let's Get Real About Vaccines Website ([link removed])
State Immunization Requirements, Exemptions, and Related Websites:
* COVID-19 Vaccine Requirements for Childcare and School (K-12) ([link removed]) as of May 2025
* DTaP (Diphtheria-Tetanus-Pertussis) Vaccine Requirements for Childcare and Elementary School ([link removed]) as of May 2025
* Hepatitis A Vaccine Requirements for Childcare and School (K–12) ([link removed]) as of May 2025
* Hepatitis B Vaccine Requirements for Childcare and School (K–12) ([link removed]) as of May 2025
* Hepatitis B Vaccine Requirements for Colleges and Universities ([link removed]) as of May 2025
* Hib Vaccine Requirements for Childcare ([link removed]) as of May 2025
* HPV (Human Papillomavirus) Vaccine Requirements for Secondary School ([link removed]) as of May 2025
* Influenza Vaccine Requirements for Childcare and Pre-K ([link removed]) as of May 2025
* Meningococcal ACWY (MenACWY) Vaccine Requirements for Secondary School ([link removed]) as of May 2025
* Meningococcal ACWY (MenACWY) Vaccine Requirements for Colleges and Universities ([link removed]) as of May 2025
* MMR (Measles-Mumps-Rubella) Vaccine Requirements for Childcare and School (K–12) ([link removed]) as of May 2025
* Pneumococcal Conjugate Vaccine (PCV) Requirements for Childcare ([link removed]) as of May 2025
* Polio Vaccine Requirements for Childcare and School (K–12) ([link removed]) as of May 2025
* Rotavirus Vaccine Requirements for Childcare ([link removed]) as of May 2025
* Tdap (Tetanus-Diphtheria-Pertussis) Vaccine Requirements for Secondary School ([link removed]) as of May 2025
* Varicella Vaccine Requirements for Childcare and School (K–12) ([link removed]) as of May 2025
* Exemptions Permitted for State Childcare and School (K-12) Immunization Requirements ([link removed]) as of May 2025
* State Immunization Websites ([link removed])
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Featured Resources
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Migration Health Initiative offers hepatitis B resources for those serving sub-Saharan African and Asian immigrant communities in the United States
Mitigation Health Initiative (MHI), part of the Task Force for Global Health, offers Protect Your Family ([link removed]) , a hepatitis B education campaign for organizations serving sub-Saharan African and Asian immigrant communities in the United States. Hepatitis B is common all over the world, but some countries in Africa and Asia have higher incidence. This campaign offers education materials that are community-informed, customizable, and culturally validated. These free materials, including a Hepatitis B Dialogue Guide ([link removed]) , were created with input from community leaders and are offered in print, digital, audio, and video formats; are customizable; and are available in 15 languages.
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View the campaign resources ([link removed] ) . To have print materials from this campaign shipped to you or your organization at no cost, please complete this form ([link removed]) .
MHI will offer a virtual webinar that introduces the campaign, titled Practical Approaches to Adult-Dose Hepatitis B Vaccine Promotion in Newcomer Communities, ([link removed]) at 1:00 p.m. (ET) on August 20. See the upcoming event story below for details.
Register for the webinar ([link removed]) .
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It’s National Immunization Awareness Month! Use these resources to encourage vaccination.
August is National Immunization Awareness Month ([link removed]) (NIAM). This annual observance highlights the importance of protecting people of all ages against vaccine-preventable diseases through on-time vaccination.
Multiple partners offer resources, including social media messaging that you can use in your NIAM communication.
* Voices for Vaccines' (VFV) NIAM 2025 web page ([link removed]) includes key messages and sample social media content, organized by week, to focus positive public attention on immunizations.
* Immunize Canada and Vaccine Ambassadors partnered on an NIAM campaign ([link removed]) , which includes images, posters, and social media content.
* Vaccinate Your Family's #FirstDayVax campaign ([link removed]) reminds families that vaccines should be part of every back-to-school checklist. Find the shareable assets in the #FirstDayVax toolkit ([link removed]) , also available in Spanish ([link removed]) .
[link removed](English)/History%20Lessons?dl=0&preview=7.png&rlkey=8sagslzfeiq2zpc81svnhvwqi&subfolder_nav_tracking=1
During NIAM, encourage your patients to schedule appointments to get up to date on annual exams and recommended vaccines. Research shows that healthcare providers remain the most trusted source of vaccine information for parents and patients.
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Notable Publications
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“Emergency Department Survey of Vaccination Knowledge, Vaccination Coverage, and Willingness to Receive Vaccines in an Emergency Department Among Underserved Populations—Eight U.S. Cities, April–December, 2024” published in MMWR
CDC published Emergency Department Survey of Vaccination Knowledge, Vaccination Coverage, and Willingness to Receive Vaccines in an Emergency Department Among Underserved Populations — Eight U.S. Cities, April–December, 2024 ([link removed]) on August 7 in MMWR. A portion of the summary appears below.
U.S. adult vaccination coverage data are limited, especially among populations lacking primary health care access. . . .
In a multicenter emergency department (ED) survey of vaccine knowledge, self-reported vaccination status, and willingness to receive vaccines if offered in an ED, 49.4% of non–critically ill adult participants had not heard of at least one CDC-recommended vaccine, and 85.9% had missed one or more. Overall, 46.4% of participants who were not up to date with recommended vaccines said they would accept one or more missing vaccines if offered during their ED visit; 86.7% of those participants said they would accept all missing vaccines. . . .
EDs could be explored as settings to offer vaccination screening, recommendations, counseling, and referrals to increase vaccination coverage among underserved populations.
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Access the MMWR article in HTML ([link removed]) or PDF ([link removed]) .
Related Link
* CDC: MMWR main page ([link removed]) providing access to the MMWR family of publications
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Journal of Adolescent Health publishes supplement on adolescent well visits and vaccination
In August 2025, the Journal of Adolescent Health published an open-access supplemental issue on the theme of adolescent well visits and vaccination ([link removed]) . Titles of the articles in this supplement include:
* The Adolescent Platform—An Ever-Evolving Construction Project
* Policies Affecting Adolescent Immunization Platform Visits
* The Historical Impact of the Adolescent Immunization Platform in the United States
* The Adolescent Immunization Platform: The Past and Future
* Early Adolescent Immunization Schedule Preferences: U.S. National Online Survey of Parents of Children Aged 9–10 Years
A national survey of parents by Zimet, et al. ([link removed]) , reported:
As part of a US survey of parents/guardians of children aged 9–10 years, we elicited preferences across 4 early adolescent vaccination schedule scenarios . . .
Most parents/guardians preferred the current schedule (52.1%) and most chose early initiation of HPV vaccination (i.e., HPV at age 9, second dose at age 10, with tetanus, diphtheria, and acellular pertussis and meningococcal ACWY at age 11) as least preferred (53.9%). Preferences varied significantly by the child’s current HPV vaccination status and by the intent to vaccinate. . . .
Given the variability in preferences, expanding the targeted ages for routine HPV vaccination to 9–12 years may ensure the broadest acceptance of HPV vaccination as part of the early adolescent schedule.
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“Safety of JN.1-Updated mRNA COVID-19 Vaccines” published in JAMA
In its July 28 issue, JAMA published Safety of JN.1-Updated mRNA COVID-19 Vaccines ([link removed] ) . The reassuring results of this very large Danish study found no significant increases in the risk of 29 different plausible adverse events in the 4 weeks after vaccination. A portion of the abstract appears below:
No statistically significant increases in the rate of hospital contacts for any of 29 adverse events were observed during the 28-day risk period after receipt of a [2024–25] JN.1-containing mRNA vaccine compared with reference period rates (Figure). For example, the incidence rate ratio was 0.84 . . . for ischemic cardiac events, 0.92 . . . for intracranial bleeding, and 1.12 . . . for myocarditis. . . .
In this nationwide cohort study [from Denmark], no increased risk of 29 adverse events was observed after vaccination with the updated COVID-19 mRNA vaccine containing the SARS-CoV-2 Omicron JN.1 lineage in approximately 1 million adults. Limitations include that residual confounding and health care use bias cannot be excluded even with the use of within-individual comparisons.
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Upcoming Events
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Virtual: North Dakota State University Center for Immunization Research and Education hosts webinar titled “The Role of Vaccines in Eradicating and Eliminating Diseases” on August 18 at 1:00 p.m. (ET); CE credit offered
The North Dakota State University Center for Immunization Research and Education will host a webinar titled The Role of Vaccines in Eradicating and Eliminating Diseases ([link removed]) , from 1:00 p.m. (ET) on August 18. The speaker will be Walter Orenstein, MD, professor emeritus at Emory University.
Attendees will learn about the difference between eradication and elimination and the critical role of disease surveillance in preventing outbreaks. Dr. Orenstein will also discuss why high-income countries’ investments in global vaccination efforts protect us all—locally and globally.
Free CME and CPE will be provided to live attendees.
Register for the webinar ([link removed]) .
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Virtual: Migration Health Initiative offers webinar titled “Practical Approaches to Adult-Dose Hepatitis B Vaccine Promotion in Newcomer Communities” on August 20 at 1:00 p.m. (ET)
Mitigation Health Initiative (MHI), part of the Task Force for Global Health, offers a virtual webinar titled Practical Approaches to Adult-Dose Hepatitis B Vaccine Promotion in Newcomer Communities ([link removed]) at 1:00 p.m. (ET) on August 20. Attendees will learn about practical, culturally responsive tools to help build trust, engage in meaningful conversations, and support informed decision-making around hepatitis B screening and vaccination.
During the webinar, MHI will introduce its campaign, Protect Your Family ([link removed]) , a hepatitis B education campaign created for organizations serving sub-Saharan African and Asian immigrant communities in the United States.
Register for the webinar ([link removed]) .
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Register for Immunize.org Website Office Hours. Ask questions and learn about the VIS web section on September 10 at 4:00 p.m. (ET) or September 11 at 12:00 p.m. (ET). Recorded sessions archived.
To learn simple tips and tricks for using our website efficiently, please register for our next set of Website Office Hours on Wednesday, September 10, at 4:00 p.m. (ET) ([link removed]) or Thursday, September 11, at 12:00 p.m. (ET) ([link removed]) . The same content will be covered in both sessions.
We will open each 45-minute session with a short, live demonstration on navigating the popular VIS website section on Immunize.org. You can submit questions when you register or live on Zoom during the session.
Register today for Immunize.org Website Office Hours (content is the same for both):
* Wednesday, September 10, at 4:00 p.m. (ET) ([link removed])
* Thursday, September 11, at 12:00 p.m. (ET) ([link removed])
The archive of previous Website Office Hours content ([link removed]) is posted at Immunize.org’s "Webinars & Videos" page.
Mark your calendar ([link removed]) for future Immunize.org Website Office Hours.
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For more upcoming events, visit our Calendar of Events ([link removed]) .
Editorial Information
Editor-in-Chief
Kelly L. Moore, MD, MPH
Managing Editor
John D. Gr
äbenstein, RPh, PhD
Associate Editor
Sharon G. Humiston, MD, MPH
Writer/Publication Coordinator
Taryn Chapman, MS
Courtnay Londo, MA
Style and Copy Editor
Marian Deegan, JD
Web Edition Managers
Arkady Shakhnovich
Jermaine Royes
Contributing Writer
Laurel H. Wood, MPA
Technical Reviewer
Kayla Ohlde
About IZ Express
Immunize.org welcomes redistribution of this issue of IZ Express or selected articles.
When you do so, please add a note that Immunize.org is the source of the material and provide a link to this issue ([link removed]) .
IZ Express is supported in part by Grant No. NH23IP922654 from the National Center for Immunization and Respiratory Diseases, CDC. Its contents are solely the responsibility of Immunize.org and do not necessarily represent the official views of CDC.
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Issue 1,827: August 13, 2025
Top Stories
* CDC data show vaccination coverage drops and exemptions rise (again) among kindergarteners for the 2024–25 school year (#IZX1)
* All pending ACIP recommendations from June meeting are now official: clesrovimab for RSV prevention and universal seasonal influenza vaccination (#IZX2)
* Immunize.org issues updated standing orders template for RSV vaccination of older adults to include high-risk adults age 50 through 74 years (#IZX3)
* Immunize.org updates “Standing Orders for Administering Recombinant Zoster Vaccine (Shingrix) to Adults” template to include manufacturer-filled syringe option (#IZX4)
* Immunize.org posts “Influenza Vaccine Products for the 2025–2026 Influenza Season” (#IZX5)
* Immunize.org updates "Checklist of Current Versions of U.S. COVID-19 Vaccination Guidance and Clinic Support Tools" (#IZX6)
* Watch CDC’s COCA webinar “Clinician Update on Measles Cases and Outbreaks in the United States” on August 14 at 2:00 p.m. (ET); CE credit offered (#IZX7)
* Immunize.org remembers our friend, Dr. Larry Pickering, shaper of U.S. vaccination policy (#IZX8)
* Immunize.org’s Hepatitis B Birth Dose Honor Roll recognizes 590 institutions, including one new honoree (#IZX9)
* Which pneumococcal vaccine is due for an 80-year-old who received a dose of PPSV23 at 65? Watch the 2-minute answer, part of the Ask the Experts Video Series on YouTube. (#IZX10)
* Vaccines in the news (#IZX11)
Immunize.org Website and Clinical Resources
* Spotlight on the website: LetsGetRealAboutVaccines.org: “Learn About Children’s Vaccines” (#IZX12)
* Summary: Updated Immunize.org clinical resources released in June and July (#IZX13)
Featured Resources
* Migration Health Initiative offers hepatitis B resources for those serving sub-Saharan African and Asian immigrant communities in the United States (#IZX14)
* It’s National Immunization Awareness Month! Use these resources to encourage vaccination. (#IZX15)
Notable Publications
* “Emergency Department Survey of Vaccination Knowledge, Vaccination Coverage, and Willingness to Receive Vaccines in an Emergency Department Among Underserved Populations—Eight U.S. Cities, April–December, 2024” published in MMWR (#IZX16)
* Journal of Adolescent Health publishes supplement on adolescent well visits and vaccination (#IZX17)
* “Safety of JN.1-Updated mRNA COVID-19 Vaccines” published in JAMA (#IZX18)
Upcoming Events
* Virtual: North Dakota State University Center for Immunization Research and Education hosts webinar titled “The Role of Vaccines in Eradicating and Eliminating Diseases” on August 18 at 1:00 p.m. (ET); CE credit offered (#IZX19)
* Virtual: Migration Health Initiative offers webinar titled “Practical Approaches to Adult-Dose Hepatitis B Vaccine Promotion in Newcomer Communities” on August 20 at 1:00 p.m. (ET) (#IZX20)
* Register for Immunize.org Website Office Hours. Ask questions and learn about the VIS web section on September 10 at 4:00 p.m. (ET) or September 11 at 12:00 p.m. (ET). Recorded sessions archived. (#IZX21)
Editorial Information (#Editorial)
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Top Stories
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CDC data show vaccination coverage drops and exemptions rise (again) among kindergarteners for the 2024–25 school year
On July 31, CDC released U.S. data ([link removed]) on vaccination coverage and exemptions from the 2024–25 school year. Vaccination coverage among kindergartners declined for all reported vaccines from the year before, from 92.1% for DTaP to 92.5% for MMR and polio vaccine. These national numbers mask wide variability of coverage rates. For example: In Idaho, 21.5% of kindergarten students lacked documentation of at least two doses of MMR, while just 1.8% lacked 2-dose documentation in Connecticut. Coverage for MMR, DTaP, polio vaccine, and varicella vaccine decreased in more than half of states. Nationwide, about 286,000 kindergartners had no documentation of completing the MMR series.
[link removed]
For the 2024–25 school year, exemptions among kindergarteners for one or more vaccines increased from 3.3% in the 2023–24 school year to 3.6%. Exemptions increased in 36 states and the District of Columbia, with 17 states reporting exemption incidence exceeding 5%. About 138,000 kindergarteners were exempted from one or more vaccination requirements.
[link removed]
Related Links
* CDC: Vaccination Coverage and Exemptions among Kindergartners ([link removed]) web page
* Immunize.org: Official Guidance: State Policies ([link removed]) main page
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All pending ACIP recommendations from June meeting are now official: clesrovimab for RSV prevention and universal seasonal influenza vaccination
On August 4, the CDC Director accepted the June 25–26 ACIP recommendation ([link removed]) that the RSV preventive antibody clesrovimab (Enflonsia, Merck) be added as an option for protection of infants younger than age 8 months born during or entering their first RSV season. There is no preference between nirsevimab (Beyfortus, Sanofi) and clesrovimab for eligible infants. Only nirsevimab is licensed and recommended for older infants and toddlers at high risk who are entering their second RSV season. This is now an official CDC recommendation.
On August 4, CDC updated the ACIP Recommendations ([link removed]) web page to show that on July 22, the HHS Secretary accepted the June ACIP recommendation for routine annual influenza vaccination of all people age 6 months and older who do not have contraindications. This notice was added to the Secretary’s previously listed July 22 acceptance of the ACIP recommendation ([link removed]) to use 2025–26 seasonal influenza vaccines that do not contain thimerosal as a preservative.
All recommendations ([link removed]) from the June 25–26 ACIP meeting have now been accepted. Immunize.org is in the process of updating its materials to reflect these new official recommendations.
Related Links
* CDC: ACIP Recommendations ([link removed]) web page
* Immunize.org: News and Updates: Official Release Repository ([link removed]) main page
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Immunize.org issues updated standing orders template for RSV vaccination of older adults to include high-risk adults age 50 through 74 years
Immunize.org updated its Standing Orders for Administering Respiratory Syncytial Virus Vaccine (RSV) to Adults Age 50 Years and Older ([link removed]) template to reflect the recommendation, adopted in June 2025, expanding the vaccination recommendation for adults at high risk from age 60 through 74 to age 50 through 74. The optimal time to be vaccinated begins in August before the typical fall RSV season begins, although vaccination may occur at any time of year, if needed. At this time, revaccination of previously vaccinated people is not recommended. Meaningful RSV protection lasts at least 2 years, and possibly longer. All unvaccinated adults age 75 years or older are also recommended to receive an RSV vaccine. All eligible adults may receive any one of the three licensed vaccines:
* Abrysvo, Pfizer
* Arexvy, GSK
* mResvia, Moderna
[link removed]
Related Links
* Immunize.org: Clinical Resources: Standing Orders Templates ([link removed]) main page
* Immunize.org: Vaccines A–Z: RSV (Respiratory Syncytial Virus) ([link removed]) main page
* Immunize.org: Clinical Resources A–Z ([link removed]) main page, where you can filter by topic, vaccine, language, or other criteria
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Immunize.org updates “Standing Orders for Administering Recombinant Zoster Vaccine (Shingrix) to Adults” template to include manufacturer-filled syringe option
Immunize.org updated its Standing Orders for Administering Recombinant Zoster Vaccine (Shingrix) to Adults ([link removed]) template to include availability of new Shingrix (GSK) packaging. Now, in addition to the 2-vial package that requires reconstitution, there is a manufacturer-filled syringe option that does not require reconstitution.
[link removed]
Related Links
* Immunize.org: Clinical Resources: Standing Orders Templates ([link removed]) main page
* Immunize.org: Vaccines A–Z: Zoster (Shingles) ([link removed]) web page
* Immunize.org: Clinical Resources A–Z ([link removed]) main page, where you can filter by topic, vaccine, language, or other criteria
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Immunize.org posts “Influenza Vaccine Products for the 2025–2026 Influenza Season”
Immunize.org posted Influenza Vaccine Products for the 2025–2026 Influenza Season ([link removed]) , our popular 1-page reference document, to list all products available for the 2025–26 influenza season. A new note addresses the ACIP recommendation ([link removed]) to use 2025–26 seasonal influenza vaccine packages that do not contain thimerosal as a preservative; availability of preservative-containing multidose vials is expected to vary by manufacturer.
[link removed]
Related Links
* Immunize.org: Vaccines A–Z: Influenza ([link removed]) web page
* Immunize.org: Clinical Resources A–Z ([link removed]) main page, where you can filter by topic, vaccine, language, or other criteria
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Immunize.org updates "Checklist of Current Versions of U.S. COVID-19 Vaccination Guidance and Clinic Support Tools"
Immunize.org published the August 7 version of its Checklist of Current Versions of U.S. COVID-19 Vaccination Guidance and Clinic Support Tools ([link removed]) . This resource checklist is updated when significant changes are made to COVID-19 vaccine resources.
The August 7 version includes revised links to updated 2024–25 Formula COVID-19 vaccine fact sheets and package inserts reflecting:
* Updated labeling of mRNA vaccines to include safety information about the rare risk of myocarditis and pericarditis following vaccination
* Revised indications for COVID-19 vaccines based on age and presence of high-risk conditions
* Addition of new package inserts for mNexspike (Moderna) and Nuvaxovid (Novavax), licensed by FDA in recent weeks (these vaccines currently are not available)
Several CDC resources were removed from the checklist (e.g., the 2024–25 recommended COVID-19 immunization schedule and vaccine At-a-Glance sheets) because CDC removed them from its website. Resources for the 2025–26 season, including new Immunize.org standing orders templates for 2025–2026 Formula COVID-19 vaccines, will be added as they become available.
[link removed]
The resource checklist is updated when significant new COVID-19 vaccine resources are released. The date of the current version of the checklist appears within the footer. All who offer COVID-19 vaccination should review reference materials in use and replace as needed with the most current versions.
Related Links
* CDC: U.S. COVID-19 Vaccine Product Information ([link removed]) main page
* CDC: Interim Clinical Considerations ([link removed]) main page for use of COVID-19 vaccines
* Immunize.org: Vaccines A–Z: COVID-19 ([link removed]) main page
* Immunize.org: Clinical Resources A–Z ([link removed]) main page, where you can filter by topic, vaccine, language, or other criteria
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Watch CDC’s COCA webinar “Clinician Update on Measles Cases and Outbreaks in the United States” on August 14 at 2:00 p.m. (ET); CE credit offered
CDC will host a Clinician Outreach and Communication Activity (COCA) call titled Clinician Update on Measles Cases and Outbreaks in the United States ([link removed]) at 2:00 p.m. (ET) on August 14. Presenters will discuss the current epidemiology of measles in the United States and address common clinical questions about preventing, identifying, and testing for measles. Presenters will also summarize MMR vaccination recommendations and considerations.
A recording of the COCA presentation will be archived on the COCA Calls web page ([link removed]) .
Free CE credit (including CME, CPE, and CNE) will be offered for this COCA call.
[link removed]
As of August 6, CDC reported 1,356 confirmed measles cases ([link removed]) in 2025 in 40 states, including the first cases reported this year in Wisconsin.
CDC only requires reporting of laboratory-confirmed measles cases. Cases without laboratory testing for confirmation are not included in these numbers. Actual numbers of cases are, therefore, higher than confirmed case counts.
A map of 2025 measles cases ([link removed]) in the contiguous United States, as of August 4, from the Johns Hopkins International Vaccine Access Center ([link removed]) , appears below. The U.S. Measles Tracker ([link removed]) website includes state and county-level data.
[link removed]
Related Links
* CDC: Measles Cases and Outbreaks ([link removed]) main page
* CDC: Be Ready for Measles Toolkit ([link removed])
* AAP: How to Protect Your Children During a Measles Outbreak ([link removed]) web page
* Johns Hopkins Bloomberg School of Public Health Center for Outbreak Response Innovation: Measles Outbreak Response ([link removed]) main page
* Immunize.org: Vaccines A–Z: Measles ([link removed]) main page
* Immunize.org: Ask the Experts: MMR (Measles, Mumps, and Rubella) ([link removed]) web page
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Immunize.org remembers our friend, Dr. Larry Pickering, shaper of U.S. vaccination policy
Larry K. Pickering, MD, FAAP, who served as executive secretary of the ACIP from 2005 to 2015, died at age 81 on July 1.
Dr. Pickering served on the National Vaccine Advisory Committee from 2017 to 2020 and was senior adviser to the director of the CDC’s National Center for Immunization and Respiratory Diseases. Dr. Pickering edited the American Academy of Pediatrics’ Red Book: Report of the Committee on Infectious Diseases editions published in 2000, 2003, 2006, 2009, and 2012. He was an associate editor of the 1994 and 1997 editions. For more on Dr. Pickering’s remarkable dedication to the health of children, see the article in AAP News ([link removed]) .
A memorial service will be held in September 2025 to honor his enduring legacy in pediatric infectious disease and public health. For more information, please see his obituary ([link removed]) .
[link removed]
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Immunize.org’s Hepatitis B Birth Dose Honor Roll recognizes 590 institutions, including one new honoree
Immunize.org is pleased to welcome one new institution into its Hepatitis B Birth Dose Honor Roll ([link removed](healthcare) ) , which now recognizes 590 honorees. The new birthing institution appears below with its reported hepatitis B birth dose coverage rates in parentheses.
* Hazard ARH Regional Medical Center, Hazard, KY (95%)
Please join us in recognizing these honorees with sustained excellence that qualify for an additional year:
* Capital Health Medical Center – Hopewell, Pennington, NJ (91%) (5 years)
* Elmhurst Hospital, Elmhurst, IL (91%) (5 years)
* Lawrence General Hospital, Lawrence, MA (97%) (6 years)
The Honor Roll includes birthing institutions from 50 states, the District of Columbia, American Samoa, Guam, Puerto Rico, Northern Mariana Islands, and U.S. military hospitals overseas.
[link removed](healthcare)
The Honor Roll is a key part of Immunize.org’s initiative urging the nation’s hospitals to Give Birth to the End of Hep B ([link removed]) . Hospitals and birthing centers are recognized for attaining high coverage for hepatitis B vaccine at birth and meeting additional criteria. The How to Apply ([link removed]) web page provides information on the criteria for inclusion in the Hepatitis B Birth Dose Honor Role and the application form.
Honorees receive an 8.5" x 11" color certificate suitable for printing and framing. Their acceptance is announced through Immunize.org’s social media channels and to IZ Express’s readers.
Please visit the Hepatitis B Birth Dose Honor Roll web page that lists these institutions and celebrates their vigorous efforts to protect infants from perinatal hepatitis B transmission.
Related Immunize.org Resources
* Give Birth to the End of Hep B ([link removed]) main page
* Hepatitis B Birth Dose Honor Roll ([link removed](healthcare)) web page
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Which pneumococcal vaccine is due for an 80-year-old who received a dose of PPSV23 at 65? Watch the 2-minute answer, part of the Ask the Experts Video Series on YouTube.
This week, our featured episode from the Ask the Experts Video Series addresses the current pneumococcal vaccination options for an 80-year-old who received a dose of PPSV23 at age 65 ([link removed]) . The video briefly explains the reasoning behind giving one dose of PCV20 or one dose of PCV21, but no additional dose of PPSV23.
The 2-minute video is available on our YouTube channel ([link removed]) , along with our full collection of quick video answers to popular Ask the Experts ([link removed]) questions.
[link removed]
Like, follow, and share Immunize.org’s social media accounts and encourage colleagues and others interested in vaccination to do likewise.
* Facebook at ImmunizeOrg ([link removed])
* Instagram at ImmunizeOrg ([link removed])
* LinkedIn at ImmunizeOrg ([link removed])
* YouTube at ImmunizeOrg ([link removed])
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Vaccines in the news
These recent articles convey the potential risks of vaccine-preventable diseases and the importance of vaccination.
* Gavi, The Vaccine Alliance: Vaccine Hesitancy: How Social and Technological Issues Converged to Spawn Mistrust ([link removed]) (8/6/25)
* Guardian: COVID Cases Rising in US as Officials Plan to Restrict Booster Vaccines ([link removed]) (8/525)
* Contemporary Pediatrics: Aligning Vaccinations with the Start of a New School Year ([link removed]) (8/4/25)
* CIDRAP: KFF Poll Shows Most Americans Plan to Skip Fall COVID Booster ([link removed]) (8/4/25)
* CNN: HHS Further Constrains Certain Vaccine Advisers to the CDC, Limiting Their Input in Evidence Reviews ([link removed]) (8/1/25)
* Medpage Today: Vaccine Expert: My Grandchild Has Autism, but Vaccines Aren't to Blame ([link removed]) [commentary from Immunize.org board member Kathryn M. Edwards, MD] (7/31/25)
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Immunize.org Website and Clinical Resources
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Spotlight on the website: LetsGetRealAboutVaccines.org: "Learn About Children’s Vaccines"
Our newest website, Let’sGetRealAboutVaccines.org, is a trustworthy, parent-friendly platform that delivers factual vaccine guidance. It equips both families and providers with tools to advocate for childhood vaccination confidently.
This week we spotlight the Learn About Children’s Vaccines ([link removed]) section of this website. Found under the first menu tab, this section offers clear information to help families separate fact from fiction and to learn why most parents make sure their children receive vaccines.
The main page summarizes the protection childhood vaccines offer and provides links to additional information. Five additional pages are available from this page and from the menu:
* Vaccine-Preventable Diseases ([link removed]) : Details about illnesses that vaccines help prevent, grouped by age category. This includes information about vaccine effectiveness and possible side effects.
* Vaccine Safety ([link removed]) : Insights into how vaccines are developed and evaluated for safety. This subsection explains safety reporting.
* Vaccine Science ([link removed]) : Explanations of how the human immune system and vaccines work.
* Vaccination Schedule ([link removed]) : Guidance on when children should receive specific vaccines and how the vaccine schedule is developed.
* Common Questions ([link removed]) : Answers to parents’ frequently asked questions.
We hope you find this section of LetsGetRealAboutVaccines.org useful. Please share these links with anyone looking for credible, unbiased information about childhood vaccines.
To learn simple tips and tricks for using the website efficiently, view the archived Website Office Hours: Let's Get Real About Vaccines website ([link removed] ) webinar for more information.
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Summary: Updated Immunize.org clinical resources released in June and July
IZ Express regularly provides readers with information about Immunize.org’s new and updated educational materials for healthcare professionals and handouts for patients. All Immunize.org materials are free to distribute.
In case you missed them during recent weeks, the following new and updated materials were posted:
Immunize.org Materials for Clinicians
Standing Orders Templates for Administering:
* Meningococcal ACWY Vaccine to Adults ([link removed])
* Meningococcal ACWY Vaccine to Children and Teens ([link removed])
Materials Supporting Immunization Services:
* Administering Vaccines: Dose, Route, Site, and Needle Size ([link removed])
* Vaccine Administration Record for Adults ([link removed])
* Vaccine Administration Record for Children and Teens ([link removed])
* Notification of Immunization Letter Template ([link removed])
Immunize.org Webinars:
* Website Office Hours: News & Updates ([link removed])
* Website Office Hours: Let's Get Real About Vaccines Website ([link removed])
State Immunization Requirements, Exemptions, and Related Websites:
* COVID-19 Vaccine Requirements for Childcare and School (K-12) ([link removed]) as of May 2025
* DTaP (Diphtheria-Tetanus-Pertussis) Vaccine Requirements for Childcare and Elementary School ([link removed]) as of May 2025
* Hepatitis A Vaccine Requirements for Childcare and School (K–12) ([link removed]) as of May 2025
* Hepatitis B Vaccine Requirements for Childcare and School (K–12) ([link removed]) as of May 2025
* Hepatitis B Vaccine Requirements for Colleges and Universities ([link removed]) as of May 2025
* Hib Vaccine Requirements for Childcare ([link removed]) as of May 2025
* HPV (Human Papillomavirus) Vaccine Requirements for Secondary School ([link removed]) as of May 2025
* Influenza Vaccine Requirements for Childcare and Pre-K ([link removed]) as of May 2025
* Meningococcal ACWY (MenACWY) Vaccine Requirements for Secondary School ([link removed]) as of May 2025
* Meningococcal ACWY (MenACWY) Vaccine Requirements for Colleges and Universities ([link removed]) as of May 2025
* MMR (Measles-Mumps-Rubella) Vaccine Requirements for Childcare and School (K–12) ([link removed]) as of May 2025
* Pneumococcal Conjugate Vaccine (PCV) Requirements for Childcare ([link removed]) as of May 2025
* Polio Vaccine Requirements for Childcare and School (K–12) ([link removed]) as of May 2025
* Rotavirus Vaccine Requirements for Childcare ([link removed]) as of May 2025
* Tdap (Tetanus-Diphtheria-Pertussis) Vaccine Requirements for Secondary School ([link removed]) as of May 2025
* Varicella Vaccine Requirements for Childcare and School (K–12) ([link removed]) as of May 2025
* Exemptions Permitted for State Childcare and School (K-12) Immunization Requirements ([link removed]) as of May 2025
* State Immunization Websites ([link removed])
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Featured Resources
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Migration Health Initiative offers hepatitis B resources for those serving sub-Saharan African and Asian immigrant communities in the United States
Mitigation Health Initiative (MHI), part of the Task Force for Global Health, offers Protect Your Family ([link removed]) , a hepatitis B education campaign for organizations serving sub-Saharan African and Asian immigrant communities in the United States. Hepatitis B is common all over the world, but some countries in Africa and Asia have higher incidence. This campaign offers education materials that are community-informed, customizable, and culturally validated. These free materials, including a Hepatitis B Dialogue Guide ([link removed]) , were created with input from community leaders and are offered in print, digital, audio, and video formats; are customizable; and are available in 15 languages.
[link removed]
View the campaign resources ([link removed] ) . To have print materials from this campaign shipped to you or your organization at no cost, please complete this form ([link removed]) .
MHI will offer a virtual webinar that introduces the campaign, titled Practical Approaches to Adult-Dose Hepatitis B Vaccine Promotion in Newcomer Communities, ([link removed]) at 1:00 p.m. (ET) on August 20. See the upcoming event story below for details.
Register for the webinar ([link removed]) .
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It’s National Immunization Awareness Month! Use these resources to encourage vaccination.
August is National Immunization Awareness Month ([link removed]) (NIAM). This annual observance highlights the importance of protecting people of all ages against vaccine-preventable diseases through on-time vaccination.
Multiple partners offer resources, including social media messaging that you can use in your NIAM communication.
* Voices for Vaccines' (VFV) NIAM 2025 web page ([link removed]) includes key messages and sample social media content, organized by week, to focus positive public attention on immunizations.
* Immunize Canada and Vaccine Ambassadors partnered on an NIAM campaign ([link removed]) , which includes images, posters, and social media content.
* Vaccinate Your Family's #FirstDayVax campaign ([link removed]) reminds families that vaccines should be part of every back-to-school checklist. Find the shareable assets in the #FirstDayVax toolkit ([link removed]) , also available in Spanish ([link removed]) .
[link removed](English)/History%20Lessons?dl=0&preview=7.png&rlkey=8sagslzfeiq2zpc81svnhvwqi&subfolder_nav_tracking=1
During NIAM, encourage your patients to schedule appointments to get up to date on annual exams and recommended vaccines. Research shows that healthcare providers remain the most trusted source of vaccine information for parents and patients.
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Notable Publications
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“Emergency Department Survey of Vaccination Knowledge, Vaccination Coverage, and Willingness to Receive Vaccines in an Emergency Department Among Underserved Populations—Eight U.S. Cities, April–December, 2024” published in MMWR
CDC published Emergency Department Survey of Vaccination Knowledge, Vaccination Coverage, and Willingness to Receive Vaccines in an Emergency Department Among Underserved Populations — Eight U.S. Cities, April–December, 2024 ([link removed]) on August 7 in MMWR. A portion of the summary appears below.
U.S. adult vaccination coverage data are limited, especially among populations lacking primary health care access. . . .
In a multicenter emergency department (ED) survey of vaccine knowledge, self-reported vaccination status, and willingness to receive vaccines if offered in an ED, 49.4% of non–critically ill adult participants had not heard of at least one CDC-recommended vaccine, and 85.9% had missed one or more. Overall, 46.4% of participants who were not up to date with recommended vaccines said they would accept one or more missing vaccines if offered during their ED visit; 86.7% of those participants said they would accept all missing vaccines. . . .
EDs could be explored as settings to offer vaccination screening, recommendations, counseling, and referrals to increase vaccination coverage among underserved populations.
[link removed]
Access the MMWR article in HTML ([link removed]) or PDF ([link removed]) .
Related Link
* CDC: MMWR main page ([link removed]) providing access to the MMWR family of publications
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Journal of Adolescent Health publishes supplement on adolescent well visits and vaccination
In August 2025, the Journal of Adolescent Health published an open-access supplemental issue on the theme of adolescent well visits and vaccination ([link removed]) . Titles of the articles in this supplement include:
* The Adolescent Platform—An Ever-Evolving Construction Project
* Policies Affecting Adolescent Immunization Platform Visits
* The Historical Impact of the Adolescent Immunization Platform in the United States
* The Adolescent Immunization Platform: The Past and Future
* Early Adolescent Immunization Schedule Preferences: U.S. National Online Survey of Parents of Children Aged 9–10 Years
A national survey of parents by Zimet, et al. ([link removed]) , reported:
As part of a US survey of parents/guardians of children aged 9–10 years, we elicited preferences across 4 early adolescent vaccination schedule scenarios . . .
Most parents/guardians preferred the current schedule (52.1%) and most chose early initiation of HPV vaccination (i.e., HPV at age 9, second dose at age 10, with tetanus, diphtheria, and acellular pertussis and meningococcal ACWY at age 11) as least preferred (53.9%). Preferences varied significantly by the child’s current HPV vaccination status and by the intent to vaccinate. . . .
Given the variability in preferences, expanding the targeted ages for routine HPV vaccination to 9–12 years may ensure the broadest acceptance of HPV vaccination as part of the early adolescent schedule.
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“Safety of JN.1-Updated mRNA COVID-19 Vaccines” published in JAMA
In its July 28 issue, JAMA published Safety of JN.1-Updated mRNA COVID-19 Vaccines ([link removed] ) . The reassuring results of this very large Danish study found no significant increases in the risk of 29 different plausible adverse events in the 4 weeks after vaccination. A portion of the abstract appears below:
No statistically significant increases in the rate of hospital contacts for any of 29 adverse events were observed during the 28-day risk period after receipt of a [2024–25] JN.1-containing mRNA vaccine compared with reference period rates (Figure). For example, the incidence rate ratio was 0.84 . . . for ischemic cardiac events, 0.92 . . . for intracranial bleeding, and 1.12 . . . for myocarditis. . . .
In this nationwide cohort study [from Denmark], no increased risk of 29 adverse events was observed after vaccination with the updated COVID-19 mRNA vaccine containing the SARS-CoV-2 Omicron JN.1 lineage in approximately 1 million adults. Limitations include that residual confounding and health care use bias cannot be excluded even with the use of within-individual comparisons.
[link removed]
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Upcoming Events
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Virtual: North Dakota State University Center for Immunization Research and Education hosts webinar titled “The Role of Vaccines in Eradicating and Eliminating Diseases” on August 18 at 1:00 p.m. (ET); CE credit offered
The North Dakota State University Center for Immunization Research and Education will host a webinar titled The Role of Vaccines in Eradicating and Eliminating Diseases ([link removed]) , from 1:00 p.m. (ET) on August 18. The speaker will be Walter Orenstein, MD, professor emeritus at Emory University.
Attendees will learn about the difference between eradication and elimination and the critical role of disease surveillance in preventing outbreaks. Dr. Orenstein will also discuss why high-income countries’ investments in global vaccination efforts protect us all—locally and globally.
Free CME and CPE will be provided to live attendees.
Register for the webinar ([link removed]) .
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Virtual: Migration Health Initiative offers webinar titled “Practical Approaches to Adult-Dose Hepatitis B Vaccine Promotion in Newcomer Communities” on August 20 at 1:00 p.m. (ET)
Mitigation Health Initiative (MHI), part of the Task Force for Global Health, offers a virtual webinar titled Practical Approaches to Adult-Dose Hepatitis B Vaccine Promotion in Newcomer Communities ([link removed]) at 1:00 p.m. (ET) on August 20. Attendees will learn about practical, culturally responsive tools to help build trust, engage in meaningful conversations, and support informed decision-making around hepatitis B screening and vaccination.
During the webinar, MHI will introduce its campaign, Protect Your Family ([link removed]) , a hepatitis B education campaign created for organizations serving sub-Saharan African and Asian immigrant communities in the United States.
Register for the webinar ([link removed]) .
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Register for Immunize.org Website Office Hours. Ask questions and learn about the VIS web section on September 10 at 4:00 p.m. (ET) or September 11 at 12:00 p.m. (ET). Recorded sessions archived.
To learn simple tips and tricks for using our website efficiently, please register for our next set of Website Office Hours on Wednesday, September 10, at 4:00 p.m. (ET) ([link removed]) or Thursday, September 11, at 12:00 p.m. (ET) ([link removed]) . The same content will be covered in both sessions.
We will open each 45-minute session with a short, live demonstration on navigating the popular VIS website section on Immunize.org. You can submit questions when you register or live on Zoom during the session.
Register today for Immunize.org Website Office Hours (content is the same for both):
* Wednesday, September 10, at 4:00 p.m. (ET) ([link removed])
* Thursday, September 11, at 12:00 p.m. (ET) ([link removed])
The archive of previous Website Office Hours content ([link removed]) is posted at Immunize.org’s "Webinars & Videos" page.
Mark your calendar ([link removed]) for future Immunize.org Website Office Hours.
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For more upcoming events, visit our Calendar of Events ([link removed]) .
Editorial Information
Editor-in-Chief
Kelly L. Moore, MD, MPH
Managing Editor
John D. Gr
äbenstein, RPh, PhD
Associate Editor
Sharon G. Humiston, MD, MPH
Writer/Publication Coordinator
Taryn Chapman, MS
Courtnay Londo, MA
Style and Copy Editor
Marian Deegan, JD
Web Edition Managers
Arkady Shakhnovich
Jermaine Royes
Contributing Writer
Laurel H. Wood, MPA
Technical Reviewer
Kayla Ohlde
About IZ Express
Immunize.org welcomes redistribution of this issue of IZ Express or selected articles.
When you do so, please add a note that Immunize.org is the source of the material and provide a link to this issue ([link removed]) .
IZ Express is supported in part by Grant No. NH23IP922654 from the National Center for Immunization and Respiratory Diseases, CDC. Its contents are solely the responsibility of Immunize.org and do not necessarily represent the official views of CDC.
IZ Express Disclaimer (http:// [link removed])
ISSN: 2771-8085
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