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Editor's Pick
New Aging Clock Forecasts Dementia, Disease Risk from Single MRI Scan
 Researchers from Duke University, Harvard University, and the University of Otago have developed a new tool that can now estimate how fast a person is aging using a single MRI scan of the brain. Called DunedinPACNI, the noninvasive MRI-based biomarker can quantify the rate of biological aging of people in midlife to forecast risks for dementia, chronic disease, and death in older adulthood. Details of the new algorithm, which is freely available on GitHub, are published in Nature Aging.
To develop the tool the researchers used data from the Dunedin Study, a longitudinal cohort that has tracked the health of 1,037 individuals born in 1972–1973 in New Zealand. Over nearly two decades, participants were repeatedly assessed on biomarkers including blood pressure, kidney and lung function, cholesterol, glucose levels, and dental health. These data allowed researchers to calculate a Pace of Aging score for each participant.
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WorkWorkWorkAfter Xi - Foreign Affairs (No paywall) For more than a decade, Chinese politics has been defined by one man: Xi Jinping. Since Xi assumed leadership of the Chinese Communist Party in 2012, he has made himself into a strongman ruler. Work 
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WorkWorkWorkWorkHow McKinsey lost its edge - The Economist (No paywall) Business has been forced to adjust itself to staggering acceleration in the rate of change,observed McKinsey, a consultancy, in a promotional pamphlet it published in 1940. What period in history has ever presented more difficult problems for the executive? Naturally, demand for McKinseys advice was soaring, it wrote. 
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WorkWorkWorkPakistan's army chief is cosying up to Donald Trump - The Economist (No paywall) Field Marshal Asim Munir, Pakistans army chief, could hardly have wished for more. For almost two years, he had been under fire at home over his meddling in politics. Wracked by debt and insurgent violence, his country had been sidelined in geopolitics as America and other rich countries courted India, Pakistans arch-rival. And yet there he was, enjoying a private lunch with Donald Trump in the White House on June 18th, just over a month after Pakistans brief conflict with India. Then, at the end of July, came further snubs for India: branding it a dead economy, Mr Trump imposed tariffs of 25% while hailing a new trade deal with Pakistan. WorkWork TradeBriefs Publications are read by over 100,000 Industry Executives About Us | Advertise | Privacy PolicyUnsubscribe (one-click) You are receiving this mail because of your subscription with TradeBriefs.
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