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Welcome to our second quarterly newsletter of 2025!

We recently announced that Justin Sandefur has joined Open Philanthropy to lead our new program on Economic Growth in Low- & Middle-Income Countries, and Matt Clancy will lead our work on Abundance & Growth ([link removed]) ([link removed]) ([link removed]) ([link removed]). We’re delighted to have found leaders who will help these programs fulfill their potential.


We are continuing to grow our team — see here or the end of the newsletter for open roles and opportunities to get involved ([link removed]). And keep reading for more updates and highlights from this quarter!

Best,
Jeremy Klemin
Content Editor
Updates

In addition to filling two senior grantmaking roles, we:
* Made 11 grants totaling more than $1.5 million through our request for proposals on effective giving. Read more about the process here ([link removed]) ([link removed]).
* Published a deep dive on how we use back-of-the-envelope calculations in our Global Health & Wellbeing grantmaking ([link removed]).
* Wrote about grantee Amy Pickering and her efforts to expand access to clean water. ([link removed]).

* Made the case for why vaccine development is a promising (and neglected) philanthropic opportunity ([link removed]).

Open Philanthropy in the News
Media coverage of our programs and grantees:
* TIME featured Cari Tuna and Dustin Moskovitz on its list of the 100 most influential people in philanthropy ([link removed]).
* NPR covered a Stanford randomized controlled trial on how stacking bricks differently could help Bangladesh fight air pollution ([link removed]) ([link removed]).
* The New York Times reported on the work of the Centre for Pesticide Suicide Prevention in Suriname ([link removed]) ([link removed]).
* The Boston Globe and The Hill reported on our support for a tuberculosis vaccine study, run by Dr. Sarah Fortune at Harvard, that was at risk after it suddenly lost funding from the National Institutes of Health ([link removed]) ([link removed]) ([link removed]).
* News-Medical wrote about a project by Dr. Donald Ingber to use AI modeling to identify broad-spectrum antiviral drugs against coronaviruses ([link removed]) ([link removed]).
* The New Yorker quoted Ajeya Cotra, senior advisor in Potential Risks from Advanced AI, in a piece about the need for non-industry perspectives in shaping the future of AI ([link removed]).
* The Financial Times covered the first major conference on mirror life, organized in part by the Mirror Biology Dialogues Fund ([link removed])([link removed]).
* Nature and Politico covered the launch of the Medical Evidence Project, run by The Center for Scientific Integrity ([link removed]) ([link removed]) ([link removed]) ([link removed]).
* TIME named Christian Happi as one of its 100 most influential people of 2025 ([link removed]) ([link removed]).
* Bloomberg covered Dr. Flaminia Catteruccia's research on malaria bednet innovation (originally published in Nature) ([link removed]) ([link removed]) ([link removed]) ([link removed]).
* The Washington Post covered Target Malaria’s work to reduce vector mosquito populations in sub-Saharan Africa ([link removed]) ([link removed]).

Interviews with Open Philanthropy staff:
* Cari Tuna, Open Philanthropy’s chair, spoke about our approach to grantmaking at Stanford’s Philanthropy Innovation Summit ([link removed]).
* Jacob Trefethen, program director in Global Health & Wellbeing, launched Hard Drugs, a new podcast about medical innovation. The podcast is a collaboration between Jacob and Saloni Dattani of Works in Progress ([link removed]) ([link removed]) ([link removed]).
* Matt Clancy, senior program officer in Abundance & Growth, was quoted in an Inside Higher Education piece on science policy ([link removed]).
* Ajeya Cotra, senior advisor in Potential Risks from Advanced AI, sat down with Open Philanthropy grantee and AI Snake Oil co-author Arvind Narayanan to discuss the pace of AI development ([link removed]) ([link removed]) ([link removed]). The exchange was published by Asterisk Magazine.

Writing by Open Philanthropy Staff
* Lewis Bollard and Emma Buckland of our Farm Animal Welfare team co-wrote a piece about the 2025 cage-free deadline for many of the world’s largest companies ([link removed]).
* Matt Clancy, senior program officer in Abundance & Growth, wrote about the case for funding R&D in developing countries ([link removed]).
* Deena Mousa, interim lead researcher in GHW Cause Prioritization, wrote about detecting airborne pathogens for Asimov Press and AI art residencies for The Verge ([link removed]) ([link removed]).
* David Roodman, senior advisor in GHW Cause Prioritization, wrote about his experience serving as the hypothetical “judge” of a dispute over the results of an economics paper ([link removed]). You can read his full write-up on the dispute here ([link removed]).
* Joe Carlsmith, senior research analyst in GCR Worldview Investigations, released the sixth article in his series on solving the AI alignment problem ([link removed]).
* Julian Hazell, program associate in Potential Risks from Advanced AI, launched Secret Third Thing, a new blog about transformative AI. So far, he has written about building defensive technology and the importance of AI security ([link removed]) ([link removed]).
* Alex Lawsen, senior program associate in Potential Risks from Advanced AI, wrote about how he uses large language models in his work ([link removed]).
* James Hu, program associate in Global Public Health Policy, co-wrote a piece for Works in Progress about recent advances in the battle against lead poisoning ([link removed]).
* Jacob Trefethen, program director in Global Health & Wellbeing, wrote about some of his favorite science writing from the last two years ([link removed]).

Grantee Updates
* The Clinton Health Access Initiative announced a landmark agreement to provide affordable access to sickle cell disease diagnosis in low- and middle-income countries ([link removed])([link removed]) ([link removed]).
* Innovate Animal Ag published a report showing the rapid adoption of in-ovo chicken sexing, which has led to 175 million male embryos being removed from eggs before hatching (instead of being slaughtered as chicks) ([link removed]) ([link removed]).
* Humane Society International has been securing wins across Asia: companies representing ~270 restaurants in Japan and Thailand have nearly or entirely transitioned to cage-free supply chains ([link removed]).
* The Lead Exposure Elimination Project released an exciting annual review ([link removed]), including major advances toward lead paint reduction in Pakistan and Nigeria ([link removed]).

New Grants
Photo courtesy of YIMBY Melbourne
We announced a number of grants, including:

In Abundance & Growth:
* YIMBY Melbourne for general support. YIMBY Melbourne advocates for the reform of restrictive land use regulations throughout Australia that limit housing supply and drive up costs ([link removed]).
* The Center for Scientific Integrity to support the launch of the Medical Evidence Project, a targeted effort to identify untrustworthy research papers that influence treatment guidelines and future research avenues ([link removed]) ([link removed]).

In Farm Animal Welfare:
* Catalyst to support its work on cage-free reforms in Thailand and other Southeast Asian countries ([link removed]).
* Çiftlik Hayvanlarını Koruma Derneği (CHKD) for general support ([link removed]). CHKD is a Turkish organization dedicated to improving farm animal welfare standards, primarily for chicken and fish.

In Effective Giving & Careers:
* Rethink Priorities to support general operations for its Global Health & Development team ([link removed]) ([link removed]).
* Ambitious Impact for general support ([link removed]). Ambitious Impact conducts research on ideas for highly impactful charities and helps founders create charities that implement those ideas.

In Potential Risks from Advanced AI:
* Speculative Technologies to support a 15-week AI safety leadership training program ([link removed]).
* The University of Texas at Austin to support research led by Professor Scott Aaronson on several topics at the intersection of AI safety and computational complexity theory ([link removed]) ([link removed]).

In Global Catastrophic Risks Capacity Building:
* The London Initiative for Safe AI (LISA) for general support ([link removed]). LISA is a U.K. charity and research center that works to advance education in AI safety, reduce risks from uncontrolled or misused AI systems, and contribute to the safe development, use, and governance of AI.
* The University of Chicago to support the Existential Risk Laboratory (formerly known as the Chicago School of Existential Risk), a summer research fellowship for undergraduate and graduate students focused on reducing existential risks ([link removed]).

In Scientific Research:
* UC Berkeley to support work led by Professor Amy Pickering to develop and evaluate low-cost in-line water chlorination devices to improve drinking water quality and reduce the burden of diarrheal diseases ([link removed]) ([link removed]).
* Stanford University to support work led by Professor Mark Davis to develop an in vitro immunological system for characterizing the efficacy of vaccine candidates ([link removed]) ([link removed]).

In Global Health R&D:
* The London School of Hygiene and Tropical Medicine to support a study on the health and economic impacts of the tuberculosis vaccine candidate VPM1002 in low‐ and middle‐income countries ([link removed]) ([link removed]).
* The Liverpool School of Tropical Medicine to support the establishment of a formal coordination network designed to improve our understanding of how and when to address malaria in school-aged children in sub-Saharan Africa ([link removed]).

In Global Aid Policy:
* Civita to support a program aimed at increasing aid effectiveness ([link removed]).

In Biosecurity & Pandemic Preparedness:
* Brown University’s Pandemic Center for operational support ([link removed]). The Pandemic Center works to reduce vulnerabilities and increase resilience to pandemics, other biological emergencies, and the second-degree harms they pose.

In Global Public Health Policy:
* Project Unleaded to support research led by Dr. Jenna Forsyth to develop and demonstrate a new reference method for measuring lead in paint, using portable X-ray fluorescence (XRF) devices ([link removed]) ([link removed])([link removed]).
* IDinsight to support a project to conduct surveys across ten Indian states on household air pollution and potential sources of lead exposure, using IDinsight's DataDelta India Panel platform ([link removed]) ([link removed]).

In Forecasting:
* FutureSearch to support research on automating the generation of forecasting questions ([link removed]).
* The Forecasting Research Institute to support its work on projects to advance the science of forecasting and to increase the relevance of forecasting for high-stakes policy decisions ([link removed]).

To see more grants we've awarded, visit our grants page ([link removed]).
Jobs and Other Opportunities

We’re hiring for:
* A generalist Program Associate/Senior Program Associate on our Abundance & Growth team to work across several different programmatic areas ([link removed]) (deadline July 27).
* A specialist Senior Program Associate/Program Officer on our Abundance & Growth team to work deeply on one or two specific programmatic areas (deadline July 27) ([link removed]).
* A Salesforce Solutions Architect and Senior Administrator to help design and build complex Salesforce solutions for a growing user base (deadline July 16) ([link removed]).
* Operations roles based in either SF or DC (rolling deadline) ([link removed]).

As always, please consider referring candidates to these roles — if we hire someone you referred, we’ll give you $5,000 ([link removed])([link removed]).

We also have:
* A variety of funding opportunities, including fellowships, scholarships, support for group organizers, and funding for career development and transition ([link removed])([link removed]).
* A general application to let us know you'd be interested in working at Open Philanthropy ([link removed]).

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