Dear John,

Have you ever noticed our logo? It’s a butterfly.

You might think it’s because the bright colors are welcoming to our young patients. That’s true. But there’s more. A butterfly represents something important to all of us at Children’s Hospital Los Angeles: the science and beauty of transformation. That’s the driving force behind everything we do. We help kids get through unthinkable illnesses and walk out of our hospital happier, while supporting their families every step of the way. We live out our mission to create hope and build healthier futures.

And, for the next few days, you can have a greater impact on these transformations: every dollar you give will TRIPLE in impact, up to $100,000.

Please help CHLA make the absolute most of this triple match with a donation of $10 TODAY.

Transformations take time, dedication, and support.

With over 1,600 ongoing clinical research studies and 597 clinical trials, CHLA is one of the largest and most productive pediatric research facilities in the United States. And because we’re a research institute and a hospital, the discoveries happening here can be fast-tracked to the kids in our care who need it most. We can’t afford to lose a moment and that’s why we’re turning to you.

Thanks to your support, CHLA has made major breakthroughs, including:

• A revolutionary new treatment that gives hemophilia patients new freedom. CHLA researchers were at the forefront of validating a new gene therapy for hemophilia, a blood clotting disorder that causes uncontrollable bleeding. "I was so stunned when my care team told me that if everything goes well, we can just discontinue my weekly infusions," says 24-year-old Ryan. "When I was a kid, I was basically told this is what I’d be doing for the rest of my life." Donate $10 to bring new hope to families. >>
• A groundbreaking gene therapy that has been a game-changer for muscular dystrophy. At 4 years old, Eliot was the first patient at CHLA to receive Elevidys, a new treatment for Duchenne muscular dystrophy. Before his treatment, Eliot got winded just walking down the block, but today he runs and jumps with ease. Donate $10 to support more clinical trials like this one. >>
• A potential new, less-toxic approach to treating leukemia that greatly minimizes the harmful short-term and long-term side effects. "This would be a completely different way to kill cancer," says Yong-Mi Kim, MD, PhD, MPH, an investigator in the Cancer and Blood Disease Institute at CHLA. "If it works, you may not even need chemotherapy." Double your impact for pioneering research with a $10 gift. >>

Every breakthrough that happens at CHLA means hope and transformation for a family. That’s what your $10 donation today can provide.

Thank you for your dedication and commitment to improving children’s health, and for believing, like we do, that every child deserves hope and healing.

Sincerely,

James F. Amatruda, MD, PhD Chief, Division of Pediatric Hematology-Oncology Director, Cancer and Blood Disease Institute Alfred E. Mann Family Foundation Chair in Cancer Research