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IZ Express #1,820: Mpox vaccine recommendations, Canadian immunization resources, mounting measles cases, and more
| From | Immunize.org <[email protected]> |
| Subject | IZ Express #1,820: Mpox vaccine recommendations, Canadian immunization resources, mounting measles cases, and more |
| Date | June 25, 2025 10:47 AM |
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Issue 1,820: June 25, 2025
Top Stories
* "Use of JYNNEOS (Smallpox and Mpox Vaccine, Live, Nonreplicating) for Persons Aged ≥18 Years at Risk for Mpox During an Mpox Outbreak: Recommendations of the Advisory Committee on Immunization Practices—United States, 2023" published in MMWR
* Canada Day is July 1! Here’s a summary of vaccination information and advocacy in Canada.
* Confirmed measles cases increase to 1,214 across 34 states; encourage vaccination
* "Do I Need to Restart the PCV Series If a Child Started the Series with PCV13?” Watch the 1-minute synopsis, part of the Ask the Experts Video Series on YouTube
* Vaccines in the news
Immunize.org Website and Clinical Resources
* Spotlight on the website: Find answers you need quickly within "Ask the Experts"
Featured Resources
* Kaiser Family Foundation publishes an overview of how vaccine recommendations affect insurance coverage requirements
* Keep the 2025 immunization schedules at your fingertips! Order laminated 2025 U.S. immunization. schedule booklets from Immunize.org.
* Immunize.org's elegantly designed "Vaccines Save Lives" black enamel pins remind patients and families why we work so hard to prevent disease
Notable Publications
* “Advisory Committee on Immunization Practices at a Crossroads” published in JAMA
* “Clade II Mpox Infections Among Cruise Ship Passengers and Crew Members—United States, 2024” published in MMWR
Global News
* “Clade Ib Mpox Outbreak—Kenya, July 2024–February 2025” published in MMWR
Upcoming Events
* Today, virtual: June 25–26 ACIP meeting with new 8-member committee and 2-day agenda, including votes on RSV and influenza vaccines
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Top Stories
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"Use of JYNNEOS (Smallpox and Mpox Vaccine, Live, Nonreplicating) for Persons Aged ≥18 Years at Risk for Mpox During an Mpox Outbreak: Recommendations of the Advisory Committee on Immunization Practices—United States, 2023" published in MMWR
CDC published Use of JYNNEOS (Smallpox and Mpox Vaccine, Live, Nonreplicating) for Persons Aged ≥18 Years at Risk for Mpox During an Mpox Outbreak: Recommendations of the Advisory Committee on Immunization Practices—United States, 2023 ([link removed]) on June 19 in MMWR. Portions of the article appear below.
CDC provides interim vaccination guidance for self-limited mpox outbreaks; however, a clade IIb outbreak that began in 2022 has had a protracted course, and the risk for U.S. mpox outbreaks has increased. . . .
On February 22, 2023, ACIP voted to recommend the 2-dose JYNNEOS vaccination series for persons aged ≥18 years who are considered to be at risk for mpox during an mpox outbreak. On October 25, 2023, ACIP voted to recommend the 2-dose JYNNEOS vaccination series for persons aged ≥18 years who are at risk for acquiring mpox during the ongoing clade IIb outbreak that began in 2022. For the latter vote, persons at risk included 1) MSM who, during the past 6 months, have had or anticipate experiencing at least one of the following: a new diagnosis of one or more sexually transmitted infections, more than one sex partner, sex at a commercial sex venue, or sex in association with a large public event in a geographic area where mpox transmission is occurring; 2) sexual partners of persons who have any of these risk factors; and 3) persons who anticipate experiencing any of these risk factors.
Access the MMWR article in HTML ([link removed]) or PDF ([link removed]).
Related Links
* CDC: MMWR main page ([link removed]) providing access to the MMWR family of publications
* Immunize.org: Vaccines A–Z: Mpox ([link removed]) main page
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Canada Day is July 1! Here’s a summary of vaccination information and advocacy in Canada.
O, Canada! Recognizing Canada’s 157th national anniversary on July 1, we share these select Canadian vaccination resources. Happy Canada Day to the vaccination providers and champions among our readers in Canada!
Expert committees:
* National Advisory Committee on Immunization (NACI) ([link removed]) , counterpart to ACIP
* Committee to Advise on Tropical Medicine and Travel (CATMAT) ([link removed])
Advocacy groups:
* CANVax ([link removed]) (Canadian Vaccination Evidence Resource and Exchange Centre): search through their library of resources (curated by the Canadian Public Health Association ([link removed]) )
* Immunize Canada ([link removed]) : a national coalition of nongovernmental, professional, health, government, and private sector organizations with a specific interest in promoting the understanding and use of vaccines recommended by NACI
* Canadian Nurses Association ([link removed])
Helpful resources:
* Canadian Immunization Guide ([link removed]) , counterpart to CDC’s "The Pink Book"
* Canadian Communicable Disease Report (CCDR) ([link removed]), counterpart to MMWR
* Canadian Adverse Events following Immunization Surveillance System (CAEFISS) ([link removed])
* Public Health Agency of Canada (PHAC)
+ Immunization and vaccine awareness materials ([link removed]) (PDFs, videos)
+ Immunization Competencies for Health Professionals ([link removed])
* Canadian Paediatric Society: Education Program for Immunization Competencies (EPIC) ([link removed])
* Provincial and Territorial Routine and Catch-Up Vaccination Schedule for Infants and Children in Canada ([link removed])
* Provincial and Territorial Routine Vaccination Programs for Healthy, Previously Immunized Adults ([link removed])
* Help Eliminate Pain in Kids & Adults ([link removed]) : organization offering resources to make the vaccination experience more positive for everyone
* CARD System ([link removed]) (Comfort, Ask, Relax, Distract): strategies that will help to provide a better vaccination experience
Government links:
* Health Canada ([link removed]), counterpart to HHS
* Public Health Agency of Canada (PHAC) ([link removed]), counterpart to CDC
* Health Products and Food Branch (HPFB) ([link removed]) , counterpart to FDA
* Drug Product Database online query ([link removed]): list of drugs and vaccines permitted to be distributed within Canada, corresponding to licensed or approved status in the United States
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Confirmed measles cases increase to 1,214 across 34 states; encourage vaccination
As of June 19, CDC reported 1,214 confirmed measles cases ([link removed]) in 2025 in 34 states. The states with the most confirmed cases in 2025 are Texas (750, 61.8%) ([link removed]) and New Mexico (81, 6.7%) ([link removed]). Among confirmed cases, 12% were hospitalized, with 21% younger than age 5 years.
CDC requires reporting of only laboratory-confirmed measles cases. Cases without laboratory testing for confirmation are not included in these numbers. Actual numbers of cases are, therefore, higher than confirmed case counts.
A map of 2025 measles cases ([link removed]) in the contiguous United States, as of June 20, from the Johns Hopkins International Vaccine Access Center ([link removed]) appears below. The U.S. Measles Tracker ([link removed]) website includes state and county-level data.
Additionally, CDC offers resources for communities experiencing a measles outbreak, including infographics for families, images to help clinic personnel identify cases, guidance for caring for patients with measles ([link removed]), Travelers' Health: Global Measles ([link removed]) web page, and a Be Ready for Measles communication toolkit ([link removed]). Spanish-language resources ([link removed]) are now available on the toolkit page.
Related Links
* CDC: Measles Cases and Outbreaks ([link removed]) main page
* CDC: Be Ready for Measles Toolkit ([link removed])
* Center for Outbreak Response Innovation: Measles Outbreak Response ([link removed]) main page
* Immunize.org: Vaccines A–Z: Measles ([link removed]) main page
* Immunize.org: Standing Orders for Administering Measles, Mumps, and Rubella Vaccine to Children and Teens ([link removed]) (PDF)
* Immunize.org: Standing Orders for Administering Measles, Mumps, and Rubella Vaccine to Adults ([link removed]) (PDF)
* Immunize.org: Ask the Experts: MMR (Measles, Mumps, and Rubella) ([link removed]) web page
------------------------------------------------------------
"Do I Need to Restart the PCV Series If a Child Started the Series with PCV13?” Watch the 1-minute synopsis, part of the Ask the Experts Video Series on YouTube
This week, our featured episode from the Ask the Experts Video Series is titled Do I Need to Restart the PCV Series If a Child Started the Series with PCV13? ([link removed]) The video highlights that clinicians need not restart the vaccination series nor give additional doses. The previously administered doses of PCV 13 (Prevnar 13, Pfizer) are valid. The series may be completed with either PCV15 (Vaxneuvance, Merck) or PCV20 (Prevnar 20, Pfizer) according to the schedule.
The 1-minute video is available on our YouTube channel ([link removed]), along with our full collection of quick video answers to popular Ask the Experts ([link removed]) questions.
Like, follow, and share Immunize.org’s social media accounts and encourage colleagues and others interested in vaccination to do likewise.
* Facebook at ImmunizeOrg ([link removed])
* Instagram at ImmunizeOrg ([link removed])
* LinkedIn at ImmunizeOrg ([link removed])
* YouTube at ImmunizeOrg ([link removed])
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Vaccines in the news
These recent articles convey the potential risks of vaccine-preventable diseases and the importance of vaccination.
* STAT: Six Former CDC Vaccine Advisory Committee Chairs Warn: U.S. Risks Losing Access to Life-Saving Immunizations ([link removed]) (6/20/25)
* West Virginia Watch: Health Groups Urge Insurers to Cover COVID-19 Shots for Pregnant Women ([link removed]) (6/17/25)
* The Hill: RFK Jr.’s Vaccine Moves Raise Fears Ahead of Next School Year ([link removed]) (6/16/25)
* The Hill: How Kennedy’s Overhaul Could Make Vaccines More Expensive ([link removed]) (6/15/25)
* NPR: RFK Jr. Sent Congress ‘Medical Disinformation’ to Defend COVID Vaccine Schedule Change ([link removed]) (6/13/25)
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Immunize.org Website and Clinical Resources
------------------------------------------------------------
Spotlight on the website: Find answers you need quickly within "Ask the Experts"
Ask the Experts ([link removed]) is one of the most visited sections of the Immunize.org website. With more than 1,300 entries, it provides practical and timely answers to your questions. You may explore five subsections: Ask the Experts Overview, View All Questions, View All Video Questions, Vaccine Topics, and General Topics.
In the example shown below, the reader is interested in the effectiveness of pertussis vaccine. After choosing “Pertussis” from the “Vaccine Topics,” one may click on “All Pertussis.” From there, one can narrow the search.
* Enter a word or phrase into “Keyword Search” (labeled #1 below). Alternatively, use the keyboard find command (Ctrl F). Either will produce yellow highlighted results to aid scanning across up to 65 hits per page.
* To show all highlighted results, click “Show All Answers.” This toggle button will become “Hide All Answers” when clicked again.
* To show highlighted results only in select questions, click the show/hide caret (⌄) on the far right (labeled #2)
* Apply filters to narrow results (“Show Filters” or “Hide Filters”)
When viewing Ask the Experts, there is now a link icon (🔗, labeled #3) on the right of each question banner, next to the show/hide caret (⌄). Selecting the link icon will copy the corresponding hyperlink for that one question and answer to your clipboard. A “link copied” message will briefly be displayed.
For additional support, view these resources from Immunize.org:
* Introducing Ask the Experts ([link removed]), video (3:36)
* Introducing Ask the Experts [Mobile View] ([link removed]), video (3:36)
* Website Office Hours: Ask the Experts Website Section ([link removed]), webinar (32:35)
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Featured Resources
------------------------------------------------------------
Kaiser Family Foundation publishes an overview of how vaccine recommendations affect insurance coverage requirements
On June 13, the Kaiser Family Foundation (KFF) published ACIP, CDC, and Insurance Coverage of Vaccines in the United States ([link removed]) . This policy brief provides an overview of vaccine coverage requirements by insurance payer or program, considering vaccine recommendation changes made by the Trump Administration. The key findings can be summarized as follows:
* Almost all payers are required to cover recommended vaccines at no cost
* Vaccine coverage requirements are linked to ACIP/CDC recommendations in almost every case
* The point at which a vaccine is considered “recommended” for purposes of requiring no-cost coverage varies somewhat by payer, and in some cases was determined through subsequent rule-making or federal policy
* If ACIP or CDC vaccine recommendations were to be narrowed or removed, as recently done with COVID-19 vaccination, payers may choose to continue to provide no-cost coverage but would no longer be required to do so
Read ([link removed]) the full article ([link removed]).
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Keep the 2025 immunization schedules at your fingertips! Order laminated 2025 U.S. immunization schedule booklets from Immunize.org.
Laminated booklets of the 2025 U.S. adult immunization schedule ([link removed]) are available in the Immunize.org shop. The 2025 child and adolescent schedule booklets sold out.
The schedules are available online as PDFs from CDC ([link removed]) at no cost. Immunize.org’s laminated booklets are ideal for use in any busy healthcare setting where vaccines are given.
Adult Booklets
1 copy: $10.00
2–4 copies: $9.50 each
5–19 copies: $8.50 each
20–99 copies: $7.50 each
100–499 copies: $6.00 each
500–999 copies: $5.00 each
1,000–1,999 copies: $4.00 each
2,000+ copies: $3.25 each
Visit the Shop Immunize.org: Laminated Schedules ([link removed]) web page to view images and order today!
For additional information, call 651-647-9009 or email [email protected].
Related Links
* Immunize.org: Laminated Adult Immunization Schedules (19 and older) ([link removed]) web page
* Immunize.org: Shop Immunize.org ([link removed]) main page
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Immunize.org's elegantly designed "Vaccines Save Lives" black enamel pins remind patients and families why we work so hard to prevent disease
Immunize.org’s elegantly designed “Vaccines Save Lives” pins ([link removed]) are meaningful gifts for people who care about vaccination. The pin makes a refined statement in hard black enamel with gold lettering and edges, measuring 1.125" x 0.75". The pin features a stick-through-post with the back covered by a round rubber cap that holds the pin securely. A gold metal spring-lock clasp is also provided.
Wear these pins on clothing, ([link removed]) uniforms, and white coats to show that you value vaccines.
Click here for "Vaccines Save Lives" pin pricing and ordering information. ([link removed])
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Notable Publications
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“Advisory Committee on Immunization Practices at a Crossroads” published in JAMA
In the June 16 issue, JAMA published Advisory Committee on Immunization Practices at a Crossroads ([link removed]), an editorial written by the 17 former members of the ACIP. A portion of the editorial appears below.
ACIP committee members have always been selected through a rigorous process based on their expertise in immunology, epidemiology, pediatrics, obstetrics, internal and family medicine, geriatrics, infectious diseases, and public health. Historically, committee members were chosen because they worked at hospitals, clinics, health departments, universities, and other organizations where they dedicated themselves to caring for patients, conducting research, and helping to prevent and treat infectious diseases. Members’ deep understanding of immunization issues ensured that vaccine policies were grounded in scientific evidence, aligned with the needs of economically, socially, and medically diverse US communities, and always considered the public value, trust, and acceptability of vaccines.
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“Clade II Mpox Infections Among Cruise Ship Passengers and Crew Members—United States, 2024” published in MMWR
CDC published Clade II Mpox Infections Among Cruise Ship Passengers and Crew Members—United States, 2024 ([link removed]) on June 19 in MMWR. A portion of the summary appears below.
During the global clade II mpox outbreak, cases have disproportionately affected gay, bisexual, and other men who have sex with men (MSM). Cruise ship travel–associated mpox infections have not been previously described. . . .
During January 25–April 18, 2024, CDC was notified of eight mpox cases on four cruise ships: four among crew members and four among passengers. All cases occurred among MSM; five of eight patients had not been vaccinated against mpox. . . .
Cruise lines should consider educating crew members on symptoms, risks, and preventive measures related to mpox and working with medical personnel to facilitate mpox vaccination for eligible crew members. Cruise passengers who are recommended to get the vaccine should receive mpox vaccine before travel. For cruise voyages marketed to gay and bisexual men, mpox-prevention messaging and education before and during voyages are recommended.
Access the MMWR article in HTML ([link removed]) or PDF ([link removed]).
Related Link
* CDC: MMWR main page ([link removed]) providing access to the MMWR family of publications
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Global News
------------------------------------------------------------
“Clade Ib Mpox Outbreak—Kenya, July 2024–February 2025” published in MMWR
CDC published Clade Ib Mpox Outbreak—Kenya, July 2024–February 2025 ([link removed]) on June 19 in MMWR. A portion of the summary appears below.
Since July 2024, Kenya has been experiencing an mpox outbreak caused by clade Ib Monkeypox virus, a newly recognized subclade. . . .
Among 48 laboratory-confirmed clade Ib mpox cases diagnosed in Kenya during July 2024–February 2025, a total of 27 (56.3%) occurred among persons who worked as truck drivers, or were in contact with them, along a highway from Mombasa to Malaba, a transportation corridor that links Kenya to other East and Central African countries. Two thirds (30; 63%) of the cases were likely to have been sexually transmitted. Eleven (23%) patients also had HIV infection, one of whom died. . . .
Public health measures, including vaccination focusing on those most at risk for mpox such as truck drivers, sex workers, and persons traveling to countries with ongoing clade Ib mpox outbreaks, might help stop the spread of the disease within Kenya and to other countries.
Access the MMWR article in HTML ([link removed]) or PDF ([link removed]).
Related Link
* CDC: MMWR main page ([link removed]) providing access to the MMWR family of publications
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Upcoming Events
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Today, virtual: June 25–26 ACIP meeting with new 8-member committee and 2-day agenda, including votes on RSV and influenza vaccines
CDC is scheduled to convene the ACIP on June 25–26 with a committee of 8 new voting members following the June 9 dismissal of all 17 voting members by the Department of Health and Human Services.
The meeting was originally scheduled as a 3-day meeting. A new, shorter agenda is planned ([link removed]) . Recommendation votes are scheduled for RSV and influenza vaccines. Additionally, the agenda includes discussion of vaccines targeting anthrax, chikungunya, and COVID-19 diseases, as well as MMRV for children younger than age 5 years.
No registration is required to watch webcasts of live ACIP meetings or listen via telephone.
View meeting information ([link removed]).
View the agenda ([link removed]).
Related Links
* CDC: ACIP main page ([link removed]) for access to webcast, agendas
* CDC: ACIP: Meeting Information ([link removed]) for presentation slides, content from previous meetings, and information about future meetings
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For more upcoming events, visit our Calendar of Events ([link removed]).
Editorial Information
Editor-in-Chief
Kelly L. Moore, MD, MPH
Managing Editor
John D. Gräbenstein, RPh, PhD
Associate Editor
Sharon G. Humiston, MD, MPH
Writer/Publication Coordinator
Taryn Chapman, MS
Courtnay Londo, MA
Style and Copy Editor
Marian Deegan, JD
Web Edition Managers
Arkady Shakhnovich
Jermaine Royes
Contributing Writer
Laurel H. Wood, MPA
Technical Reviewer
Kayla Ohlde
About IZ Express
Immunize.org welcomes redistribution of this issue of IZ Express or selected articles.
When you do so, please add a note that Immunize.org is the source of the material and provide a link to this issue ([link removed]).
IZ Express is supported in part by Grant No. NH23IP922654 from the National Center for Immunization and Respiratory Diseases, CDC. Its contents are solely the responsibility of Immunize.org and do not necessarily represent the official views of CDC.
IZ Express Disclaimer (http:// [link removed])
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Issue 1,820: June 25, 2025
Top Stories
* "Use of JYNNEOS (Smallpox and Mpox Vaccine, Live, Nonreplicating) for Persons Aged ≥18 Years at Risk for Mpox During an Mpox Outbreak: Recommendations of the Advisory Committee on Immunization Practices—United States, 2023" published in MMWR
* Canada Day is July 1! Here’s a summary of vaccination information and advocacy in Canada.
* Confirmed measles cases increase to 1,214 across 34 states; encourage vaccination
* "Do I Need to Restart the PCV Series If a Child Started the Series with PCV13?” Watch the 1-minute synopsis, part of the Ask the Experts Video Series on YouTube
* Vaccines in the news
Immunize.org Website and Clinical Resources
* Spotlight on the website: Find answers you need quickly within "Ask the Experts"
Featured Resources
* Kaiser Family Foundation publishes an overview of how vaccine recommendations affect insurance coverage requirements
* Keep the 2025 immunization schedules at your fingertips! Order laminated 2025 U.S. immunization. schedule booklets from Immunize.org.
* Immunize.org's elegantly designed "Vaccines Save Lives" black enamel pins remind patients and families why we work so hard to prevent disease
Notable Publications
* “Advisory Committee on Immunization Practices at a Crossroads” published in JAMA
* “Clade II Mpox Infections Among Cruise Ship Passengers and Crew Members—United States, 2024” published in MMWR
Global News
* “Clade Ib Mpox Outbreak—Kenya, July 2024–February 2025” published in MMWR
Upcoming Events
* Today, virtual: June 25–26 ACIP meeting with new 8-member committee and 2-day agenda, including votes on RSV and influenza vaccines
------------------------------------------------------------
Top Stories
------------------------------------------------------------
"Use of JYNNEOS (Smallpox and Mpox Vaccine, Live, Nonreplicating) for Persons Aged ≥18 Years at Risk for Mpox During an Mpox Outbreak: Recommendations of the Advisory Committee on Immunization Practices—United States, 2023" published in MMWR
CDC published Use of JYNNEOS (Smallpox and Mpox Vaccine, Live, Nonreplicating) for Persons Aged ≥18 Years at Risk for Mpox During an Mpox Outbreak: Recommendations of the Advisory Committee on Immunization Practices—United States, 2023 ([link removed]) on June 19 in MMWR. Portions of the article appear below.
CDC provides interim vaccination guidance for self-limited mpox outbreaks; however, a clade IIb outbreak that began in 2022 has had a protracted course, and the risk for U.S. mpox outbreaks has increased. . . .
On February 22, 2023, ACIP voted to recommend the 2-dose JYNNEOS vaccination series for persons aged ≥18 years who are considered to be at risk for mpox during an mpox outbreak. On October 25, 2023, ACIP voted to recommend the 2-dose JYNNEOS vaccination series for persons aged ≥18 years who are at risk for acquiring mpox during the ongoing clade IIb outbreak that began in 2022. For the latter vote, persons at risk included 1) MSM who, during the past 6 months, have had or anticipate experiencing at least one of the following: a new diagnosis of one or more sexually transmitted infections, more than one sex partner, sex at a commercial sex venue, or sex in association with a large public event in a geographic area where mpox transmission is occurring; 2) sexual partners of persons who have any of these risk factors; and 3) persons who anticipate experiencing any of these risk factors.
Access the MMWR article in HTML ([link removed]) or PDF ([link removed]).
Related Links
* CDC: MMWR main page ([link removed]) providing access to the MMWR family of publications
* Immunize.org: Vaccines A–Z: Mpox ([link removed]) main page
------------------------------------------------------------
Canada Day is July 1! Here’s a summary of vaccination information and advocacy in Canada.
O, Canada! Recognizing Canada’s 157th national anniversary on July 1, we share these select Canadian vaccination resources. Happy Canada Day to the vaccination providers and champions among our readers in Canada!
Expert committees:
* National Advisory Committee on Immunization (NACI) ([link removed]) , counterpart to ACIP
* Committee to Advise on Tropical Medicine and Travel (CATMAT) ([link removed])
Advocacy groups:
* CANVax ([link removed]) (Canadian Vaccination Evidence Resource and Exchange Centre): search through their library of resources (curated by the Canadian Public Health Association ([link removed]) )
* Immunize Canada ([link removed]) : a national coalition of nongovernmental, professional, health, government, and private sector organizations with a specific interest in promoting the understanding and use of vaccines recommended by NACI
* Canadian Nurses Association ([link removed])
Helpful resources:
* Canadian Immunization Guide ([link removed]) , counterpart to CDC’s "The Pink Book"
* Canadian Communicable Disease Report (CCDR) ([link removed]), counterpart to MMWR
* Canadian Adverse Events following Immunization Surveillance System (CAEFISS) ([link removed])
* Public Health Agency of Canada (PHAC)
+ Immunization and vaccine awareness materials ([link removed]) (PDFs, videos)
+ Immunization Competencies for Health Professionals ([link removed])
* Canadian Paediatric Society: Education Program for Immunization Competencies (EPIC) ([link removed])
* Provincial and Territorial Routine and Catch-Up Vaccination Schedule for Infants and Children in Canada ([link removed])
* Provincial and Territorial Routine Vaccination Programs for Healthy, Previously Immunized Adults ([link removed])
* Help Eliminate Pain in Kids & Adults ([link removed]) : organization offering resources to make the vaccination experience more positive for everyone
* CARD System ([link removed]) (Comfort, Ask, Relax, Distract): strategies that will help to provide a better vaccination experience
Government links:
* Health Canada ([link removed]), counterpart to HHS
* Public Health Agency of Canada (PHAC) ([link removed]), counterpart to CDC
* Health Products and Food Branch (HPFB) ([link removed]) , counterpart to FDA
* Drug Product Database online query ([link removed]): list of drugs and vaccines permitted to be distributed within Canada, corresponding to licensed or approved status in the United States
------------------------------------------------------------
Confirmed measles cases increase to 1,214 across 34 states; encourage vaccination
As of June 19, CDC reported 1,214 confirmed measles cases ([link removed]) in 2025 in 34 states. The states with the most confirmed cases in 2025 are Texas (750, 61.8%) ([link removed]) and New Mexico (81, 6.7%) ([link removed]). Among confirmed cases, 12% were hospitalized, with 21% younger than age 5 years.
CDC requires reporting of only laboratory-confirmed measles cases. Cases without laboratory testing for confirmation are not included in these numbers. Actual numbers of cases are, therefore, higher than confirmed case counts.
A map of 2025 measles cases ([link removed]) in the contiguous United States, as of June 20, from the Johns Hopkins International Vaccine Access Center ([link removed]) appears below. The U.S. Measles Tracker ([link removed]) website includes state and county-level data.
Additionally, CDC offers resources for communities experiencing a measles outbreak, including infographics for families, images to help clinic personnel identify cases, guidance for caring for patients with measles ([link removed]), Travelers' Health: Global Measles ([link removed]) web page, and a Be Ready for Measles communication toolkit ([link removed]). Spanish-language resources ([link removed]) are now available on the toolkit page.
Related Links
* CDC: Measles Cases and Outbreaks ([link removed]) main page
* CDC: Be Ready for Measles Toolkit ([link removed])
* Center for Outbreak Response Innovation: Measles Outbreak Response ([link removed]) main page
* Immunize.org: Vaccines A–Z: Measles ([link removed]) main page
* Immunize.org: Standing Orders for Administering Measles, Mumps, and Rubella Vaccine to Children and Teens ([link removed]) (PDF)
* Immunize.org: Standing Orders for Administering Measles, Mumps, and Rubella Vaccine to Adults ([link removed]) (PDF)
* Immunize.org: Ask the Experts: MMR (Measles, Mumps, and Rubella) ([link removed]) web page
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"Do I Need to Restart the PCV Series If a Child Started the Series with PCV13?” Watch the 1-minute synopsis, part of the Ask the Experts Video Series on YouTube
This week, our featured episode from the Ask the Experts Video Series is titled Do I Need to Restart the PCV Series If a Child Started the Series with PCV13? ([link removed]) The video highlights that clinicians need not restart the vaccination series nor give additional doses. The previously administered doses of PCV 13 (Prevnar 13, Pfizer) are valid. The series may be completed with either PCV15 (Vaxneuvance, Merck) or PCV20 (Prevnar 20, Pfizer) according to the schedule.
The 1-minute video is available on our YouTube channel ([link removed]), along with our full collection of quick video answers to popular Ask the Experts ([link removed]) questions.
Like, follow, and share Immunize.org’s social media accounts and encourage colleagues and others interested in vaccination to do likewise.
* Facebook at ImmunizeOrg ([link removed])
* Instagram at ImmunizeOrg ([link removed])
* LinkedIn at ImmunizeOrg ([link removed])
* YouTube at ImmunizeOrg ([link removed])
------------------------------------------------------------
Vaccines in the news
These recent articles convey the potential risks of vaccine-preventable diseases and the importance of vaccination.
* STAT: Six Former CDC Vaccine Advisory Committee Chairs Warn: U.S. Risks Losing Access to Life-Saving Immunizations ([link removed]) (6/20/25)
* West Virginia Watch: Health Groups Urge Insurers to Cover COVID-19 Shots for Pregnant Women ([link removed]) (6/17/25)
* The Hill: RFK Jr.’s Vaccine Moves Raise Fears Ahead of Next School Year ([link removed]) (6/16/25)
* The Hill: How Kennedy’s Overhaul Could Make Vaccines More Expensive ([link removed]) (6/15/25)
* NPR: RFK Jr. Sent Congress ‘Medical Disinformation’ to Defend COVID Vaccine Schedule Change ([link removed]) (6/13/25)
------------------------------------------------------------
Immunize.org Website and Clinical Resources
------------------------------------------------------------
Spotlight on the website: Find answers you need quickly within "Ask the Experts"
Ask the Experts ([link removed]) is one of the most visited sections of the Immunize.org website. With more than 1,300 entries, it provides practical and timely answers to your questions. You may explore five subsections: Ask the Experts Overview, View All Questions, View All Video Questions, Vaccine Topics, and General Topics.
In the example shown below, the reader is interested in the effectiveness of pertussis vaccine. After choosing “Pertussis” from the “Vaccine Topics,” one may click on “All Pertussis.” From there, one can narrow the search.
* Enter a word or phrase into “Keyword Search” (labeled #1 below). Alternatively, use the keyboard find command (Ctrl F). Either will produce yellow highlighted results to aid scanning across up to 65 hits per page.
* To show all highlighted results, click “Show All Answers.” This toggle button will become “Hide All Answers” when clicked again.
* To show highlighted results only in select questions, click the show/hide caret (⌄) on the far right (labeled #2)
* Apply filters to narrow results (“Show Filters” or “Hide Filters”)
When viewing Ask the Experts, there is now a link icon (🔗, labeled #3) on the right of each question banner, next to the show/hide caret (⌄). Selecting the link icon will copy the corresponding hyperlink for that one question and answer to your clipboard. A “link copied” message will briefly be displayed.
For additional support, view these resources from Immunize.org:
* Introducing Ask the Experts ([link removed]), video (3:36)
* Introducing Ask the Experts [Mobile View] ([link removed]), video (3:36)
* Website Office Hours: Ask the Experts Website Section ([link removed]), webinar (32:35)
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Featured Resources
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Kaiser Family Foundation publishes an overview of how vaccine recommendations affect insurance coverage requirements
On June 13, the Kaiser Family Foundation (KFF) published ACIP, CDC, and Insurance Coverage of Vaccines in the United States ([link removed]) . This policy brief provides an overview of vaccine coverage requirements by insurance payer or program, considering vaccine recommendation changes made by the Trump Administration. The key findings can be summarized as follows:
* Almost all payers are required to cover recommended vaccines at no cost
* Vaccine coverage requirements are linked to ACIP/CDC recommendations in almost every case
* The point at which a vaccine is considered “recommended” for purposes of requiring no-cost coverage varies somewhat by payer, and in some cases was determined through subsequent rule-making or federal policy
* If ACIP or CDC vaccine recommendations were to be narrowed or removed, as recently done with COVID-19 vaccination, payers may choose to continue to provide no-cost coverage but would no longer be required to do so
Read ([link removed]) the full article ([link removed]).
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Keep the 2025 immunization schedules at your fingertips! Order laminated 2025 U.S. immunization schedule booklets from Immunize.org.
Laminated booklets of the 2025 U.S. adult immunization schedule ([link removed]) are available in the Immunize.org shop. The 2025 child and adolescent schedule booklets sold out.
The schedules are available online as PDFs from CDC ([link removed]) at no cost. Immunize.org’s laminated booklets are ideal for use in any busy healthcare setting where vaccines are given.
Adult Booklets
1 copy: $10.00
2–4 copies: $9.50 each
5–19 copies: $8.50 each
20–99 copies: $7.50 each
100–499 copies: $6.00 each
500–999 copies: $5.00 each
1,000–1,999 copies: $4.00 each
2,000+ copies: $3.25 each
Visit the Shop Immunize.org: Laminated Schedules ([link removed]) web page to view images and order today!
For additional information, call 651-647-9009 or email [email protected].
Related Links
* Immunize.org: Laminated Adult Immunization Schedules (19 and older) ([link removed]) web page
* Immunize.org: Shop Immunize.org ([link removed]) main page
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Immunize.org's elegantly designed "Vaccines Save Lives" black enamel pins remind patients and families why we work so hard to prevent disease
Immunize.org’s elegantly designed “Vaccines Save Lives” pins ([link removed]) are meaningful gifts for people who care about vaccination. The pin makes a refined statement in hard black enamel with gold lettering and edges, measuring 1.125" x 0.75". The pin features a stick-through-post with the back covered by a round rubber cap that holds the pin securely. A gold metal spring-lock clasp is also provided.
Wear these pins on clothing, ([link removed]) uniforms, and white coats to show that you value vaccines.
Click here for "Vaccines Save Lives" pin pricing and ordering information. ([link removed])
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Notable Publications
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“Advisory Committee on Immunization Practices at a Crossroads” published in JAMA
In the June 16 issue, JAMA published Advisory Committee on Immunization Practices at a Crossroads ([link removed]), an editorial written by the 17 former members of the ACIP. A portion of the editorial appears below.
ACIP committee members have always been selected through a rigorous process based on their expertise in immunology, epidemiology, pediatrics, obstetrics, internal and family medicine, geriatrics, infectious diseases, and public health. Historically, committee members were chosen because they worked at hospitals, clinics, health departments, universities, and other organizations where they dedicated themselves to caring for patients, conducting research, and helping to prevent and treat infectious diseases. Members’ deep understanding of immunization issues ensured that vaccine policies were grounded in scientific evidence, aligned with the needs of economically, socially, and medically diverse US communities, and always considered the public value, trust, and acceptability of vaccines.
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“Clade II Mpox Infections Among Cruise Ship Passengers and Crew Members—United States, 2024” published in MMWR
CDC published Clade II Mpox Infections Among Cruise Ship Passengers and Crew Members—United States, 2024 ([link removed]) on June 19 in MMWR. A portion of the summary appears below.
During the global clade II mpox outbreak, cases have disproportionately affected gay, bisexual, and other men who have sex with men (MSM). Cruise ship travel–associated mpox infections have not been previously described. . . .
During January 25–April 18, 2024, CDC was notified of eight mpox cases on four cruise ships: four among crew members and four among passengers. All cases occurred among MSM; five of eight patients had not been vaccinated against mpox. . . .
Cruise lines should consider educating crew members on symptoms, risks, and preventive measures related to mpox and working with medical personnel to facilitate mpox vaccination for eligible crew members. Cruise passengers who are recommended to get the vaccine should receive mpox vaccine before travel. For cruise voyages marketed to gay and bisexual men, mpox-prevention messaging and education before and during voyages are recommended.
Access the MMWR article in HTML ([link removed]) or PDF ([link removed]).
Related Link
* CDC: MMWR main page ([link removed]) providing access to the MMWR family of publications
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Global News
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“Clade Ib Mpox Outbreak—Kenya, July 2024–February 2025” published in MMWR
CDC published Clade Ib Mpox Outbreak—Kenya, July 2024–February 2025 ([link removed]) on June 19 in MMWR. A portion of the summary appears below.
Since July 2024, Kenya has been experiencing an mpox outbreak caused by clade Ib Monkeypox virus, a newly recognized subclade. . . .
Among 48 laboratory-confirmed clade Ib mpox cases diagnosed in Kenya during July 2024–February 2025, a total of 27 (56.3%) occurred among persons who worked as truck drivers, or were in contact with them, along a highway from Mombasa to Malaba, a transportation corridor that links Kenya to other East and Central African countries. Two thirds (30; 63%) of the cases were likely to have been sexually transmitted. Eleven (23%) patients also had HIV infection, one of whom died. . . .
Public health measures, including vaccination focusing on those most at risk for mpox such as truck drivers, sex workers, and persons traveling to countries with ongoing clade Ib mpox outbreaks, might help stop the spread of the disease within Kenya and to other countries.
Access the MMWR article in HTML ([link removed]) or PDF ([link removed]).
Related Link
* CDC: MMWR main page ([link removed]) providing access to the MMWR family of publications
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Upcoming Events
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Today, virtual: June 25–26 ACIP meeting with new 8-member committee and 2-day agenda, including votes on RSV and influenza vaccines
CDC is scheduled to convene the ACIP on June 25–26 with a committee of 8 new voting members following the June 9 dismissal of all 17 voting members by the Department of Health and Human Services.
The meeting was originally scheduled as a 3-day meeting. A new, shorter agenda is planned ([link removed]) . Recommendation votes are scheduled for RSV and influenza vaccines. Additionally, the agenda includes discussion of vaccines targeting anthrax, chikungunya, and COVID-19 diseases, as well as MMRV for children younger than age 5 years.
No registration is required to watch webcasts of live ACIP meetings or listen via telephone.
View meeting information ([link removed]).
View the agenda ([link removed]).
Related Links
* CDC: ACIP main page ([link removed]) for access to webcast, agendas
* CDC: ACIP: Meeting Information ([link removed]) for presentation slides, content from previous meetings, and information about future meetings
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For more upcoming events, visit our Calendar of Events ([link removed]).
Editorial Information
Editor-in-Chief
Kelly L. Moore, MD, MPH
Managing Editor
John D. Gräbenstein, RPh, PhD
Associate Editor
Sharon G. Humiston, MD, MPH
Writer/Publication Coordinator
Taryn Chapman, MS
Courtnay Londo, MA
Style and Copy Editor
Marian Deegan, JD
Web Edition Managers
Arkady Shakhnovich
Jermaine Royes
Contributing Writer
Laurel H. Wood, MPA
Technical Reviewer
Kayla Ohlde
About IZ Express
Immunize.org welcomes redistribution of this issue of IZ Express or selected articles.
When you do so, please add a note that Immunize.org is the source of the material and provide a link to this issue ([link removed]).
IZ Express is supported in part by Grant No. NH23IP922654 from the National Center for Immunization and Respiratory Diseases, CDC. Its contents are solely the responsibility of Immunize.org and do not necessarily represent the official views of CDC.
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