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- The top 25 stories curated by editors and fellow readers!

Editor's Pick

A Third Person Has Received a Transplant of a Genetically Engineered
Pig Kidney
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Looney, 53, is off of kidney dialysis after undergoing the procedure
at NYU Langone Health on November 25. She was discharged from the
hospital on December 6, and her doctors say she is in good health. Her
surgery is the latest in a series of similar procedures known as
xenotransplantation, the practice of transplanting organs from one
species to another.

Earlier this year, surgeons carried out pig kidney transplants in
living people for the first time. In March, 62-year-old Richard
Slayman made history when he received a kidney from a genetically
engineered pig at Massachusetts General Hospital. He was discharged
from the hospital and was initially doing well, but he died nearly two
months after the transplant. In a statement released by the hospital,
his medical team said there was no indication that his death was the
result of his transplant. In November, Slayman’s surgeon said his
death was caused by an “unexpected cardiac event,” and there was
no sign that his body had rejected the organ.

Continued here
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UnitedHealthcare CEO shooting suspect charged with first-degree murder
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The suspect escaped the scene and fled on foot, later by ebike, to
Central Park. After several days of a search in New York City,
Mangione was found and reported to police while in a McDonald’s in
Altoona, Pennsylvania, on 9 December. Police found Mangione in
possession of a firearm suppressor, a mask consistent with that worn
by the gunman, a fraudulent New Jersey ID matching the ID the man used
to check into a New York City hostel before the shooting, and a
handwritten document.

Work

Amazon and the Endangered Future of the Middle Manager
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Amazon CEO Andy Jassy delivered one of 2024's major job headlines with
his five-day office mandate, but there's a bigger tech organizational
shakeup at work.






















 










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Pfizer's 2025 forecast meets expectations and leaves room for debate
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Financial analysts polled by Visible Alpha had expected earnings per
share of $2.89 and sales of $63.2 billion. In a note to clients
Monday, Akash Tewari, an analyst at Jefferies, wrote that the
consensus among fund managers (the “buy side”) was actually lower,
with a forecasted dilute earnings per share of $2.50 to $2.70.

Work

Sanofi is the latest drug company to sue HHS over payment terms for
340B hospitals
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In its lawsuit, Sanofi argued that the program is rife with waste and
abuse. The program was created three decades ago to help hospitals and
clinics care for low-income and rural patients. Drug companies that
want to take part in Medicare or Medicaid must offer their medicines
at a discount — typically, 25% to 50%, but sometimes higher — to
participating hospitals and clinics.







You Might Like







 

 







 









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Gene-edited pig kidney transplanted into a third person, moving
xenotransplants closer to trials
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Looney said she is eagerly awaiting being able to travel again and
spend more time with her family and grandchildren. She also has
another goal for her post-transplant life: “I want to go to
Disneyworld,” she said, through laughter.

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Pharmalittle: We're reading about Congress reining in PBMs, Sanofi
suing HHS, and more
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After two years of haggling, Congress has nearly reached a deal to
rein in pharmacy benefit managers















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Gameto says first baby born using new stem-cell tech
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The company, which raised $33 million in a series B in May, is
expecting to launch a Phase 3 trial in early 2025, pending the
go-ahead from the FDA. If it goes forward, it would be the first
pivotal trial of induced pluripotent stem cells in the U.S.

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What Marty Makary will do at the FDA & what taxi drivers can teach
scientists
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Today's health news includes what to know about Marty Mackary, Trump's
pick for FDA head, plus a study on taxi drivers and Alzheimer's.







You Might Like







 

 







 









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PBMs face scrutiny from all sides, and analyzing Marty Makary's road
to the FDA
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Sarah Owermohle reports on the administration’s health care
initiatives, federal health policy, and its intersection with politics
and the courts. She joined STAT in 2022 after covering health policy
at Politico. She is also the co-author of the free, twice-weekly D.C.
Diagnosis newsletter.

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FDA deputy commissioner Namandje Bumpus to leave agency
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Namandjé Bumpus, principal deputy commissioner of the Food and Drug
Administration, is leaving the agency. Commissioner Robert Califf
shared the news with staff Tuesday morning, according to an email
reviewed by STAT.






















 









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Bipartisan task force sets health AI oversight priorities for the next
Congress
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The task force’s recommendations come at a time when a new
administration and Congress prepare to enter Washington. Though many
anticipate President-elect Donald Trump’s “AI czar” David Sacks
and the Trump administration will advocate for lessening AI
regulation, the report outlines several areas where Congress should
consider guardrails to make sure patients are protected while
encouraging adoption of AI.

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Republicans show no signs of blocking Trump's health secretary pick
RFK Jr. so far
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Rachel Cohrs Zhang reports on the intersection of health policy and
business in Washington. She covers Capitol Hill, lobbying, and federal
agencies. Her primary areas of focus are the pharmaceutical and
hospital industries. She is also the co-author of the free,
twice-weekly D.C. Diagnosis newsletter.














 









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Retiring at 62 with $1 Million in a Roth IRA: Will $2,250 Monthly
Social Security Be Enough?
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Are you a financial advisor looking to grow your business? SmartAsset
AMP helps advisors connect with leads and offers marketing automation
solutions so you can spend more time making conversions. Learn more
about SmartAsset AMP.

Work

Mark Cuban Calls Healthcare Pricing 'Horrific'- Says Hospitals and
Doctors Are 'Sub Prime Lenders' Forced To Raise Prices To Cover Losses
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What's more, Cuban intends to publish his company's direct contracts,
ensuring transparency in pricing. His ultimate vision? A health care
system where businesses contract directly with providers, cutting out
unnecessary intermediaries and reducing costs for everyone involved.






















 









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Why I Recently Bought More Shares of This Beaten Down 8%-Yielding
Dividend Stock
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Matt DiLallo has positions in Medical Properties Trust and has the
following options: short March 2025 $4 puts on Medical Properties
Trust. The Motley Fool has no position in any of the stocks mentioned.
The Motley Fool has a disclosure policy.

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Bitcoin Rally Leaves the World's Original Crypto ETFs Behind
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While this year’s net flows for Canadian Bitcoin ETFs will be
negative, Rincon of TD sees more tailwinds on the way for the crypto
ETF industry with incoming changes at the US Securities and Exchange
Commission that could lead to more types of ETFs.






















 









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Robert Kiyosaki Warns Baby Boomers Will Be 'Biggest Losers'- Suggests
Kids 'Nudge' Parents To Sell Their Homes, Stocks And Bonds 'Now'
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Deloitte's fastest-growing software company partnered with Amazon,
Walmart & Target announces the deadline to invest this year is 12/20.
– Last Chance to get 4,000 of its pre-IPO shares for just
$0.26/share!

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Ask an Advisor: After My Spouse Dies, Do I Qualify for a Full Step-Up
in Basis on Our Home, or Just the $250k Capital Gains Exemption?
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Please note that Brandon is not an employee of SmartAsset and is not a
participant in SmartAsset AMP. He has been compensated for this
article. Some reader-submitted questions are edited for clarity or
brevity.

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Nuon helps companies deploy their software into their customers' cloud
accounts | TechCrunch
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“If you think about the last 17 years of software, everything has
been built for SaaS,” Morehouse said. “We believe the next 17
years of software is going to be built for bring-your-own cloud.
It’s going to be AI first. It’s going to be designed to run in the
customer’s cloud first.”

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Exclusive: Focused Energy buys two of the world's most powerful lasers
for its fusion quest | TechCrunch
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Today, Focused Energy’s main challenge is building things quickly
enough, Mercer said. “We set our target for 2035. It’s mostly
conditioned on, how quickly can we start to move towards laser
manufacturing at scale?” he said. “Even putting a traditional
power plant on the grid in a 10-year time frame is an ambitious
process today.”

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Popular LatAm digital payment service AstroPay launches multi-currency
wallet | TechCrunch
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AstroPay itself has teams in multiple markets, including Argentina,
Brazil, Colombia, Denmark, India, Peru, Spain, the U.K., and Uruguay.
“The team is a reflection of that company we’re building as well.
So we are 320 people and we’re spread out around the world,” Sacal
said.

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Slip Robotics snags $28M for its bots that can load a truck in five
minutes | TechCrunch
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He said Slip Robotics didn’t try to scale too soon, kept quiet, and
focused on developing its robotics platform. That approach appears to
have paid off. The company, once less than a dozen people, has now
grown to about 50 employees. Importantly, he noted, Slip Robotics now
has 10 commercial customers and hundreds of bots in the field.

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Grammarly acquires productivity startup Coda, brings on new CEO |
TechCrunch
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Aisha is a consumer news reporter at TechCrunch. Prior to joining the
publication in 2021, she was a telecom reporter at MobileSyrup. Aisha
holds an honours bachelor’s degree from University of Toronto and a
master’s degree in journalism from Western University.

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Commonwealth Fusion Systems just picked its first commercial site
partly because of its proximity to Washington, DC | TechCrunch
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While CFS has its eyes on Sparc and Arc today, Needham said the
company is already beginning to think about what comes after those.
“Because of all the work we’ve done, we found a lot of great
sites,” Needham said. “Our objective as a company is not to build
a fusion power plant. It’s to build thousands.”

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AI boom masks fundraising struggles for non-AI startups | TechCrunch
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Founders of non-GenAI startups must feel like “in high school, and
they didn’t get invited to the cool party,” Hirsch said, adding
that they often have a good business, but nobody cares.

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A comprehensive list of 2024 tech layoffs | TechCrunch
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Alyssa Stringer was formerly the Audience Development Manager for
TechCrunch. She previously worked for HW Media as Audience Development
Manager across HousingWire, RealTrends and FinLedger media brands.
Prior to her experience in audience development, Alyssa worked as a
content writer and holds a Bachelor’s in Journalism at the
University of North Texas.

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The DOJ wants a Perplexity executive to testify in its Google
antitrust case | TechCrunch
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Perplexity also says that while it has agreed to provide copies of
licensing agreements “related to AI training,” Google wants all of
Perplexity’s licensing agreements and that it has asked Google to
“meet and confer” about this. 

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Trump sues Iowa newspaper over election poll claiming Harrisa??s lead
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This all comes as last week, ABC News, which is owned by Walt Disney,
agreed to pay $15m to a foundation and museum to be established by
Trump as part of a settlement in yet another defamation lawsuit that
the president-elect had launched.

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Trump lashes out at judge who refused to dismiss business fraud
conviction a?? as it happened
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"But look, as we hold our loved ones close this holiday season, we as
a nation, must renew our commitment to end ⦠gun violence, both
mass shootings, and everyday, gun violence that touches so many."

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Amazon workers across US gear up to strike this week, days before
Christmas
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Spokesperson Eileen Hands said in a statement: “The truth is that
the Teamsters have actively threatened, intimidated, and attempted to
coerce Amazon employees and third-party drivers to join them, which is
illegal and is the subject of multiple pending unfair labor practice
charges against the union.”

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New York tax preparer called a??the Magiciana?? charged for tax fraud
of $145m
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When Alvarez was charged on 15 April - tax day - this year, IRS
special agent in charge Thomas Fattorusso said that while Alvarez was
known as the magician, "he can't say abracadabra and make these
charges disappear", and that his arrest "was no magical illusion".

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US Bureau of Prisons pays a??historica?? $115m to survivors of staff
sexual abuse
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"The [BoP] is dedicated to appropriately addressing the consequences
of sexually abusive behavior at FCI Dublin. The [BoP] remains
committed to rooting out unlawful behavior and holding accountable
those who violate their oath of office," she said.

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Expert witness condemns claims by Lucy Letbya??s lawyer
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Evans said police should be able to complete their investigation
"without any distractions", as should Lady Justice Thirlwall, who is
chair of the public inquiry into the events surrounding Letby's
crimes.

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PSNI and Met policea??s unlawful spying on journalists may be tip of
the iceberg
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In a witness statement to the tribunal in May, Det Supt Brian Foster,
the head of PSNI's anti-corruption unit, was unapologetic: "The
operation above was last conducted in March 2023. It has been
suspended until the conclusion of the tribunal proceedings but it is a
valuable tool and may be used again."

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Young terrorism suspects could avoid prosecution in plan for diversion
scheme
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“The government should be stepping up to fix this by properly
funding the officers our communities need – not passing the buck to
local police chiefs to put up people’s council tax instead.”

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Avanti West Coast workers to strike on New Yeara??s Eve
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Avanti says it is assessing how much impact strikes will have but
spokesperson says disruption will be a??significanta??

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Pollution exposure linked to mental health hospital admissions, says
study
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Between 1% and 2% of the UK population have bipolar disorder in their
lifetime, with similar figures for schizophrenia. It is estimated that
about 5% of people in the UK have a personality disorder at any one
time.

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Lloyds advert banned for making false environmental claims
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“Reducing the environmental impact of our business remains a
fundamental part of our strategy and we will continue to work
alongside customers, the government, and the market to reach net zero
by 2050 or sooner.”

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a??Ankara is getting what it wantsa??: how ErdoA?ana??s balancing act
in Syria paid off
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"Post-Assad Syria grants Turkey a lot of leverage and HTS can use all
the help it can get," she says. The group is seeking to avoid
isolation and will use Turkey's input to ensure they eventually gain
recognition from the international community, she adds. But in the
interim, Turkey remains their gateway to the outside world.

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Middle East crisis: UN envoy to Syria warns conflict is not over amid
a??significant hostilitiesa?? a?? as it happened
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Israeli forces have detained at least 12 Palestinians across the
occupied West Bank since last night, the Palestinian Authority's
Prisoners and Ex-Prisoners Affairs Commission and the Palestinian
Prisoner's Society said.

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Killing of Russian general cements SBUa??s reputation for abrupt
vengeance
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Tuesday's more sophisticated assassination of Kirillov will be
celebrated in Kyiv as a textbook success. The SBU's formal name is the
Sluzhba bezpeky Ukrainy. It is now jokingly known as the "service of
god", a play in Ukrainian on the initials SBU. The agency has cemented
its reputation as an outfit that administers its own form of brutal
extrajudicial justice. It is an abrupt and swift form of vengeance,
delivered as if from the heavens.

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The chemical weapon accusations against the general killed in Moscow
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“The analyses by the OPCW designated laboratories, conducted
separately and independently from one another, confirm that the
grenade and soil samples collected from the trench contain the riot
control agent 2-Chlorobenzylidenemalononitrile known as CS,” the
body reported. Under the chemical weapons convention signed by Russia,
it added, “the use of riot control agents as a method of warfare is
prohibited”.

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Friedrich Merz lashes out at Greens as German election campaign starts
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“Whoever wants to lead a government has to be able to bring varying
interests together” and get past his own “self-importance”,
Habeck said. “That will determine his future success.”

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Spain introduces bill to combat online fake news
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Fighting disinformation is part of the government’s plan for
“democratic renewal”, launched earlier this year after a judge
began investigating Sánchez’s wife, Begoña Gómez, for alleged
corruption and influence peddling.

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a??Bad deal for taxpayersa??: huge losses from NSW forest logging,
reports reveal
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"This is just another piece of evidence to show that native forest
logging in New South Wales is economically unviable. We know that it's
ecologically unsustainable, and we know that the forestry corporation
has been losing money on its hardwood division for the last decade."

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Australians making record $295,000 median profit on home sales, report
shows
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Owen said units had always had a higher chance of making a loss, which
was attributed to supply factors and the fact that units are the
preferred investment dwelling, with low maintenance, lower price
points and generally higher rental yields.

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Push to stop NSW hospitals opting out of abortions as healthcare
a??desertsa?? exposed
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"I think it's important that there be greater clarity about the role
that regional-based hospitals play in providing access to abortion
services, and pathways for women need to be more clearly delineated,"
Shilbury said.

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Federal budget $27bn in the red and wona??t return to balance for a
decade, Myefo forecasts
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Ahead of the release, Labor boasted that it has improved the budget by
a cumulative $200bn over the six years to 2027-28 inherited from the
Coalition, despite $8.8bn of "unavoidable spending" in the mid-year
update and $16.3bn in changes to payments and programs.

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Buruli ulcer: researchers warn of flesh-eating bacteria in NSWa??s
south coast that can cause disfigurement
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Researchers said the many similarities in wildlife composition and
insect presence between coastal Victoria and southern NSW made it
likely NSW health authorities were facing progressive expansion of
ulcer-endemic areas.

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Australia news live: Alan Jones to plead not guilty after eight new
indecent assault charges; second Vanuatu earthquake
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“As you plan for the future, remember that there are many pathways
to university, regardless of your Atar. If you need guidance or
support, UAC is here to help you explore your options and take the
next step with confidence.”

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Lawyer accused of being Chinese spy in UK loses legal challenge
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Lee’s human rights were also not infringed by the issue of the
interference alert, the tribunal ruled. “The public interest in the
protection of national security outweighs the interference with C1
[Lee’s] right to respect for private life,” it said.

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Honda and Nissan to start talks on potential mega-merger
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Nissan said in a statement: “The content of the report is not
something that has been announced by either companies. As announced in
March of this year, Honda and Nissan are exploring various
possibilities for future collaboration, leveraging each other’s
strengths. If there are any updates, we will inform our stakeholders
at the appropriate time.”

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Laboura??s review of UK-China relations on hold until after chancellor
visits Beijing
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On Monday the Chinese embassy in London accused some MPs of having a
"twisted mentality towards China" and said "anti-China clamours" were
an attempt to "smear China, target against the Chinese community in
the UK and undermine normal personnel exchanges between China and the
UK".

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Vanuatu earthquake: death toll expected to rise as second quake
plunges nation into state of emergency
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While a first case was dismissed by the supreme court last week, the
former prime minister Ishmael Kalsakau has announced they are
appealing that judgment – which was due to be heard before
Christmas.

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a??Several hundreda?? North Korean troops killed fighting Ukraine,
says US official
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"I would certainly anticipate ⦠there could be remaining authority
that would transition and be available for the next administration to
use," the official said on condition of anonymity.

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Canadaa??s turmoil is harbinger of diplomatic havoc in second Trump
term
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After Freeland's exit, Trump also attacked her, describing the former
minister as "totally toxic" during the Nafta renegotiation and said
that "she will not be missed".

Work

Cyclone Chido: many missing in Mayotte as death toll rises in
south-east Africa
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He said the storm needed to trigger improvements for people living in
Mayotte’s slums: “We are overpopulated so, if there is no
long-term solution, unfortunately what is happening now will be
multiplied in the coming years.”

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UK government denies rift with Mauritian PM over Chagos Islands deal
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Ministers in the UK have said that uncertainty over the islands’
legal status threatened the base’s operation and that the deal had
support from across the US security system. Joe Biden’s
administration has offered its public backing to it.

Work

Cambridge Analytica scandal still lingering on as Meta settles with
Australian users
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In a statement, Meta displayed no contrition and said the settlement
was more or less a business decision. "We settled as it is in the best
interest of our community and shareholders that we close this chapter
on allegations that relate to past practices no longer relevant to how
Meta’s products or systems work today," a spokesperson told The
Guardian. The case took four years to resolve largely because Meta
claimed it wasn't technically doing business in Australia, but that
argument was finally slapped aside by the nation's highest court.

Work

The Audi Q6 E-Tron is an OLED dream machine
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The problem? That's a huge premium over the starting price of Audi's
most comparable gas-powered machine, the Q5, which can be had for as
little as $45,400. Is the Q6 worth the extra cost? I wouldn't
necessarily spring for the sportier SQ6, but even the base Q6 offers
far more power and tech than the Q5, plus lower running costs and a
lack of maintenance. Despite the similar name, it's in a different
class. Sure, it's a bit of a splurge, but I'd rather have the
even-numbered one in my garage.

Work

Get a free $20 Amazon gift card when you buy the Samsung Galaxy Buds 3
Pro
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According to our review, the Samsung Galaxy Buds 3 Pro earbuds have no
issue hitting its advertised battery life. With ANC on, they can last
six hours, and the charging case provides an additional 20 hours of
ANC-on usage. We also counted it among the best wireless earbuds in
2024.

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