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- The top 25 stories curated by editors and fellow readers!

Editor's Pick

Can Psychedelics Help CEOs Boost Their Leadership Skills?

[[link removed]}&lead=419599&emailid=110229&nl=daily growing
cottage industry is dedicated to the theory that mind-altering drugs
can improve business leadership.

Continued here
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Editor's Note: Robin Carhart-Harris, a neuroscientist studying the
effect of psychedelics, said that it was possible the drugs could help
leaders in the workplace. Mr. Carhart-Harris, a professor at the
University of California, San Francisco, examines people's brains on
drugs. His brain scans show that psychedelics increase entropy. Where
the brain usually tries to helpfully compress information, these drugs
have the opposite effect, which he argues could shake loose new
thinking on the knotty challenges of leadership.

Work

Many New Jersey a??dronesa?? are manned aircraft being flown lawfully,
White House says
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The Republican assemblyman Erik Peterson, whose district includes
parts of the state where the drones have been reported, said he also
attended Wednesday's meeting at a state police facility in West
Trenton. The session lasted for about 90 minutes.

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Guide to Saudi Arabia's mad stadium plans for 2034 World Cup
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Fifa has confirmed that Saudi Arabia will be awarded the 2034 World
Cup. The Gulf state emerged as the only bidder and has already started
building ambitious stadiums for the event.






















 










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A.D.H.D. Diagnoses Are Surging Among Older Americans
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Over her life, Tanya Murphy had become accustomed to hiding her
depression. In the Christian social circles in Georgia where she
raised her three children, this was the rule -- not the exception, she
said. "God forbid you have a mental health issue," said Ms.

Work

Why Crypto Bros Are So Obsessed with 'Debanking'
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Marc Andreessen made headlines recently when he brought up the issue
of "debanking" on the Joe Rogan podcast, claiming that the U.S.
government was "terrorizing" crypto companies with it.







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'There Was Almost a Utopian Feeling to It': How StumbleUpon Pioneered
the Way We Use the Internet
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StumbleUpon, a tool that led users to random websites, had a
stranglehold on millennials in the 2010s. Its influence echoes through
everything we do online.

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Designer Babies Are Teenagers Now--and Some of Them Need Therapy
Because of It
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For years now, aspiring parents have been designing their children.
Screening embryos for disease-causing genes during IVF, selecting
their future baby's sex, picking egg and sperm donors to influence
their child's traits.















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Running On Empty: How Corporate Cultures Fuel Burnout
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In my work advising organizations, I've observed a disturbing trend
that's about to reach critical mass.

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Tech predictions for 2025 and beyond
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We have entered an era of unprecedented societal challenges and rapid
technological advancements. Harnessing technology for good has become
both an ethical imperative and a profitable endeavor.







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Diagnostic accuracy of deep learning in medical imaging: a systematic
review and meta-analysis
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Deep learning (DL) has the potential to transform medical diagnostics.
However, the diagnostic accuracy of DL is uncertain. Our aim was to
evaluate the diagnostic accuracy of DL algorithms to identify
pathology in medical imaging. Searches were conducted in Medline and
EMBASE up to January 2020.

Work

The Incredibly True Story of Renting a Friend in Tokyo
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When you're alone in Tokyo and you need someone to talk to, do as the
locals do: Rent a friend.






















 









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Parkinson's Law: It's Real, So Use It
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Parkinson's Law states that "work expands so as to fill the time
available for its completion." Although it is counter-intuitive, you
will find that through practice and experience, there is a lot of
truth to this.

Work

A Guide to the Muscles You Forget to Exercise
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Add "tendon day" to your gym routine.














 









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Prices for 5 drugs were hiked without proof of new benefits, costing
the U.S. $815M in 2023, report finds
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Consequently, spending for this drug climbed by $359 million,
according to the report issued by the Institute for Clinical and
Economic Review, a nonprofit that assesses the cost-effectiveness of
medicines. The report noted that Gilead maintained that certain
important study data were “rejected” or “overlooked,” and that
in at least one instance, the analysis “contradicts standard
research practice.”

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Pfizer's blockbuster Ibrance slows tumor progression in another type
of breast cancer
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Although not a game changer for Pfizer, the data could help cushion
Ibrance’s losses of market share to Kisqali, a similar drug from
Novartis. Kisqali has shown to improve survival in advanced breast
cancer; Ibrance has not. While early data had indicated a medicine
like Ibrance, known as a CDK 4/6 inhibitor, should work in HER2+
patients, this is the first data showing that to be the case. This
could result in increased use of Ibrance in this group.






















 









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The bird flu mystery that might never get solved
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The study was published just days after, here in the U.S.,
President-elect Donald Trump suggested that he shares some of Robert
F. Kennedy Jr.’s concerns about common childhood vaccines (which, to
be clear, are scientifically unsubstantiated).

Work

The biotech news you need to read today
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However, analysts say that the bill is far from a sure bet,
particularly given the upcoming change in administrations. They
believe other legislative priorities will get more attention, despite
a focus on health care matters more broadly.






















 









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Pharmalittle: We're reading about unsupported drug price hikes, an
annual HIV prevention shot, and more
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Gilead plans to begin Phase 3 testing soon for a drug it believes
could prevent HIV infection with a single shot every year

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How RFK Jr. could impact addiction treatment
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STAT’s Lev Facher examined Robert F. Kennedy Jr.’s past statements
on drug use and his personal recovery from drug and alcohol misuse.
His philosophy toward addiction policy is inconsistent, but one thing
that stands out is that Kennedy believes the country should turn to
law enforcement, jailing those who fail to recover. 

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Investors in Padlock Therapeutics sue Bristol Myers Squibb over
'milestone' payments
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Adam Feuerstein is a senior writer and biotech columnist, reporting on
the crossroads of drug development, business, Wall Street, and
biotechnology. He is also a co-host of the weekly biotech podcast The
Readout Loud and author of the newsletter Adam’s Biotech Scorecard.

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The pharma industry's silence on RFK Jr., and efforts by parents to
develop gene therapies for their children
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Adam Feuerstein is a senior writer and biotech columnist, reporting on
the crossroads of drug development, business, Wall Street, and
biotechnology. He is also a co-host of the weekly biotech podcast The
Readout Loud and author of the newsletter Adam’s Biotech Scorecard.

Work

Centene warns Republicans against cutting Medicaid or letting ACA
subsidies expire
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Bob Herman covers health insurance, government programs, hospitals,
physicians, and other providers — reporting on how money influences
those businesses and shapes what we all pay for care. He is also the
author of the Health Care Inc. newsletter.

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When AI becomes a tool to fight insurance denials
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Mario Aguilar covers technology in health care, including artificial
intelligence, virtual reality, wearable devices, telehealth, and
digital therapeutics. His stories explore how tech is changing the
practice of health care and the business and policy challenges to
realizing tech’s promise. He’s also the co-author of the free,
twice weekly STAT Health Tech newsletter.

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Editas Medicine lays off 65% of staff and shelves lead gene-editing
program
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Editas launched with immense fanfare a decade ago, as one of the first
three companies founded around the promise of CRISPR genome editing.
But it struggled on execution, choosing to go after hard-to-reach
diseases, and it saw significant turnover as early programs failed or
stagnated. 

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CDC finds no evidence of bird flu virus in California toddler
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California is currently the epicenter of the outbreak of H5N1 in dairy
cows, with over 600 herds having tested positive for the virus since
spread there was first detected in late August. Nationally, 832 herds
in 16 states have tested positive for the virus since the outbreak in
cows was first confirmed in late March.

Work

Archer Aviation raises $430 million through equity offering, partners
with Anduril
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The San Jose, California-based air-taxi maker ended the third quarter
with $502 million of cash and cash equivalents. The latest funding
brings Archer's total capital raised to nearly $2 billion to date.

Work

Stocks will end 2025 lower due to sticky inflation, economic slowdown,
Stifel predicts
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RBC Capital Markets head of US equity strategy Lori Calvasina recently
pointed out in her 2025 outlook why economic growth meeting or
exceeding positive expectations could be crucial to the stock market
rally. Dating back to 1947, GDP has grown between 1.1% and 2% five
times. Stocks were higher just 40% in those years, with an average
decline of 3.4%. Meanwhile, in years when GDP tracked between 2.1% and
3%, stocks were higher 70% of the time, with an average return of
nearly 11%.

Work

Can You Guess What Percent Of People Retire With A $5 Million Nest
Egg? Hint: It's Way Less Than 1%
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Studies show 50% of consumers think Financial Advisors cost much more
than they do — to debunk this, this company provides matching for
free and a complimentary first call with the matched advisor.

Work

Why Intel Stock Is Gaining Today
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Keith Noonan has no position in any of the stocks mentioned. The
Motley Fool has positions in and recommends Intel. The Motley Fool
recommends Mobileye Global and recommends the following options: short
February 2025 $27 calls on Intel. The Motley Fool has a disclosure
policy.

Work

These Are the 5 Worst-Performing Stocks in the Dow Jones Industrial
Average With 2024 Almost Over
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Jeremy Bowman has positions in Nike. The Motley Fool has positions in
and recommends Merck and Nike. The Motley Fool recommends Alaska Air
Group, Amgen, Johnson & Johnson, and On Holding. The Motley Fool has a
disclosure policy.

Work

Adobe stock sinks as weak outlook stokes fears over AI monetization,
growing competition
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William Blair analyst Jake Roberge wrote in his own note to investors
early Thursday: “While in the near term we expect this guidance will
likely put an overhang on the stock as investors contemplate whether
the lack of pricing/growth tailwinds from the company’s new GenAI
solutions is due to competitive/market pressure versus Adobe playing
the long game in fostering top-of-funnel activity for its new AI
solutions, we remain positive on the long-term trajectory of the
business and believe that Adobe remains well positioned to capitalize
on the GenAI opportunity.”

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If You Had Invested $95 in Warren Buffett's Berkshire Hathaway 59
Years Ago, Here's How Much You Would Have Today
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American Express is an advertising partner of Motley Fool Money.
Selena Maranjian has positions in American Express, Apple, and
Berkshire Hathaway. The Motley Fool has positions in and recommends
Apple and Berkshire Hathaway. The Motley Fool has a disclosure policy.

Work

From $470 To $3,300 In Dividend Income in 5 Years - Investor Shares
Stock Portfolio And Tips, Says It's A 'Big Mountain To Climb'
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Dividend investing has been an efficient way for investors to protect
against inflation. For example, data shows that between 1974 and 1980,
when inflation averaged 9.3%, stocks delivered a total return of 10%,
with 5% from dividend income and 4.8% ...

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Costco tops quarterly sales, profit estimates on steady early holiday
demand
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The recent hike in its annual membership fee to $65 for Gold Star
members and $130 for Executive members resulted in earnings from the
fees rising 7.7% to $1.17 billion in the reported quarter.

Work

Warren Buffett Says Ignore 'Tarot' Card Predictions by So-Called
Experts: 'The Risks of Being Out of the Game Are Huge Compared to
Being In'
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Studies show 50% of consumers think Financial Advisors cost much more
than they do — to debunk this, this company provides matching for
free and a complimentary first call with the matched advisor.

Work

Intel Says It's an Open Question Whether to Break Up Company
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In artificial intelligence accelerator chips, where Nvidia Corp. has
taken a dominant role, Intel has struggled as well. The company’s
Gaudi chip is difficult to use, Johnston Holthaus acknowledged. Intel
is now focusing on more generic graphics-chip offerings that won’t
be great at first but will be rapidly updated to make them
competitive, she said.

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Costco posts another quarter of sales growth against an uncertain
consumer environment
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"We do also recognize that there's a benefit of the stock feeling more
affordable for our retail investors and employees who are very
important constituents for us, so we'll continue to evaluate over
time," he added.

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Broadcom Shares Jump After Chipmaker Predicts AI Sales Surge
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Bloomberg News reported earlier that Apple would start switching away
from a key Broadcom wireless chip starting next year. The iPhone maker
has been replacing suppliers’ components with in-house versions, a
trend that’s also set to hit chipmaker Qualcomm Inc.

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Emerson Electric Company (EMR) Stock Forecasts
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META_DESC_INVESTMENT_IDEA

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Intel executives say a manufacturing spinoff is possible
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Zinsner, also chief financial officer, outlined how Intel is already
separating the finances and operations of this manufacturing division
into a standalone subsidiary. Zinsner said Intel Foundry, as the
division is known, is already run separately from Intel's other
businesses and is setting up a separate operational board and business
process software system.

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Rule of 70 vs. Rule of 72: What's the Difference?
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A financial advisor can help you analyze investments and manage risk
for your portfolio. Finding a financial advisor doesn't have to be
hard. SmartAsset's free tool matches you with up to three vetted
financial advisors who serve your area, and you can have a free
introductory call with your advisor matches to decide which one you
feel is right for you. If you're ready to find an advisor who can help
you achieve your financial goals, get started now.

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Broadcom forecasts Q1 revenue above estimates on strong AI chip demand
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While hailed as a chipmaker, Broadcom has proliferated into a tech
conglomerate owing to buyouts such as its $69 billion acquisition of
cloud-computing firm VMware. The infrastructure software segment grew
196% from a year earlier to $5.82 billion in the fourth quarter.

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Schwab Found This Was the Average Retirement Income Strategy. How Does
Yours Compare?
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Are you a financial advisor looking to grow your business? SmartAsset
AMP helps advisors connect with leads and offers marketing automation
solutions so you can spend more time making conversions. Learn more
about SmartAsset AMP.

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Apple went public 44 years ago--what your $10,000 investment would be
worth today
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Berkshire’s position at the start of 2024 would currently be worth
over $220 billion, but Buffett likely won’t fret about missing the
upswing. Stock sales propelled Berkshire’s profits to $26.25 billion
last quarter, compared to a loss of $12.77 billion during Q3 a year
ago. As Fortune’s Shawn Tully recently noted, Buffett’s Apple
gambit will likely go down as one of the best wagers in the storied
investor’s career.

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Twelve Labs is building AI that can analyze and search through videos
| TechCrunch
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“The investment from In-Q-Tel reflects the versatility and potential
of our technology across many sectors, including national security,”
Lee said. “We’re always open to exploring opportunities where our
technology can have a positive, meaningful, and responsible impact
that aligns with our ethical guidelines.”

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The founders of SlideShare are making sharing docs more social with
their new platform, Jaunt | TechCrunch
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The company plans to add more features over time, including direct
messaging, a verification system, and support for video embedding.
Currently bootstrapped, Jaunt is exploring monetization strategies
such as a premium tier, and is open to incorporating ads, as well as
seeking investment from venture capitalists in the future.

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Exclusive: Evinced's $55M C round will help bring its accessibility
dev tools (and AI) to Europe
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Expect adoption of accessibility-focused tools like Evinced to
accelerate as companies continue to realize that it’s not just the
law to build with accessibility in mind, it’s just simply a good
idea.

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ServiceTitan's IPO is a big winner that could inspire fintechs |
TechCrunch
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“We expect ServiceTitan’s debut to be an encouraging indicator
that could inspire other fintech players in the extensive fintech IPO
pipeline to follow suit,” said PitchBook senior emerging technology
analyst Rudy Yang.

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A comprehensive list of 2024 tech layoffs | TechCrunch
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Alyssa Stringer was formerly the Audience Development Manager for
TechCrunch. She previously worked for HW Media as Audience Development
Manager across HousingWire, RealTrends and FinLedger media brands.
Prior to her experience in audience development, Alyssa worked as a
content writer and holds a Bachelor’s in Journalism at the
University of North Texas.

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Carta is making it too difficult to cancel subscriptions, some
founders say | TechCrunch
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Carta’s practices have come under scrutiny before. In January 2024,
coding startup Linear’s founder, Karri Saarinan, accused Carta of
sharing private cap table data, claiming that a Carta employee
contacted one of his angel investors claiming to have an offer for his
shares without notifying Saarinen first. Carta ended up exiting the
secondary stock trading market, selling it this August to stock
trading startup Public. 

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Cooler temperatures forecast to help firefighters battle Malibu
wildfire
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The Woolsey fire that roared through the area in 2018, killing three
people and destroying 1,600 homes, was sparked by Edison equipment.
Asked on Wednesday if Edison equipment was involved in the Franklin
fire, Ornelas referred all questions regarding the cause to fire
officials.

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Pete Hegseth decried out gay troops in US military as part of Marxist
agenda
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“Through don’t ask, don’t tell and women in the military and
these standards, they’re going to inevitably start to erode
standards because they want that one female special operator, that one
female Green Beret, that one female Army Ranger, that one female Navy
Seal, so they can put them on a recruiting poster and feel good about
themselves – and [that] has nothing to do with national security,”
he said.

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Inspector general finds no FBI agents were involved in January 6
attack a?? as it happened
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In addition to the group of people included in today's announcement,
the Brennan Center and a coalition of allies have been calling on the
president to commute the sentences of the more than 40 people on
federal death row to life without parole, and to thousands of people
who are serving unfairly long, racially disparate drug sentences."

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Louisville and DoJ strike police reform deal in wake of Breonna Taylor
shooting
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It remains to be seen what will happen to attempts to reach such
agreements between cities and the justice department once Trump
returns to the White House. The justice department under the first
Trump administration curtailed the use of consent decrees and the
Republican president-elect is expected to again radically reshape the
department’s priorities around civil rights.

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Suspect in UnitedHealthcare CEO killing may not have been a client,
say police
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Mangione is an Ivy League graduate from a prominent Maryland real
estate family. On Wednesday, police said investigators are looking
into an accident that injured Mangione’s back and sent him to an
emergency room in July 2023. They are also looking at his writings
about the injury and his criticism of corporate America and the US
healthcare system.

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Some jury trials may be scrapped in England and Wales as court backlog
hits record high
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Katie Kempen, the chief executive of Victim Support, which helps
victims of crimes through the court process, said: “Whilst
fundamental reform is needed, it is shortsighted to think that this
crisis will be solved without serious investment in court staff,
infrastructure and victims’ services.”

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Housing must take priority over nature, says Starmer in green belt
reform plan
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Florence Eshalomi, the chair of the housing committee, criticised the
remarks, saying: “For the shadow secretary of state to reduce this
about immigration is wrong. Think about those many children who will
be sleeping rough this Christmas.”

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Tory peer faces suspension over a??Lord Poppadoma?? remark
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Complaining that security officers had insisted on "the rules", he
told the Lords commissioner for standards: "Perhaps I need [to] try
not to be angered by this sort of senseless, inconvenient ruling."

Work

UK housing crisis: what does Laboura??s shake-up of planning rules
involve?
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The introduction of the "golden rules" do seem to represent a
relaxation of what had been previously rigid planning rules. The
Conservatives accused the government of waging a "war on rural
England", with the shadow housing secretary, Kevin Hollinrake,
claiming that most of the 1.5m proposed new homes would be going to
migrants.

Work

Police hunt for culprits after Christmas lights damaged in five
Suffolk villages
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He urged anyone with CCTV or doorbell cameras in the affected areas to
review their footage for anything that may be relevant. Anyone with
information is asked to contact Suffolk police by calling 101 or by
emailing cccidentifysuffolk.police.uk.

Work

Birmingham fairground ride crashes to the ground, injuring several
people
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“Two women were treated by ambulance staff for injuries not believed
to be serious and conveyed to Midland Metropolitan university
hospital,” a West Midlands ambulance service spokesperson said.
“Nine women and two men were assessed by medics before being given
self-care advice and discharged at the scene.”

Work

American found in Damascus appears to have been released from Syrian
prison
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Maria Cure, of SETF, said: “He has made it a priority while he’s
there to find all Americans wrongfully detained in Syria, including
Majd Kamalmaz, Austin Tice and others whose names are not public.”

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