Dear ,

Foregen continues to focus on preparations for human clinical trials! Here are the updates from last month:

Animal Trials Final Report

The final report for the animal trials, including the rat and sheep studies, will be published in two separate articles in a peer-reviewed journal. The rat study has already been submitted, and we anticipate it will be published by the end of the year. The results of the sheep study are still being drafted, as they are more complex, and are expected to be published early next year. Most importantly, Foregen does not need to wait for these reports to be published to continue progressing towards human clinical trials.

HistologiX Histology Study

A total of 12 tissue samples have been received and assessed by HistologiX. Six more are being ordered from a new source. Once these additional samples have been trimmed, embedded, sectioned, and stained, the most optimal 12 of the 18 samples will be selected, and the final phase of the study will begin. We anticipate the study’s completion by the end of the year, with the final report available in early 2025.

Preparing the Decellularization Protocol

A new research team harvested and decellularized the foreskin ECMs used in the final round of sheep trials. Members of the Foregen team traveled to meet with this team on October 25th. We toured the facilities and discussed the best ways to refine their decellularization method. The meeting was highly successful and will significantly impact our preparations for human clinical trials.

Fundraising

Thanks to our incredibly generous and supportive community, Foregen raised a total of $15,793 in October! These funds are vital for preparing for our future human clinical trials. We are deeply grateful for your support.

Your contributions can make a significant difference. Join us in developing the world’s first regenerative medicine solution for circumcised men!

Sincerely,
Ryan Jones
Chief Operations Officer