Advancing Toward Gene Therapies for Rare Epilepsies
View this email in your browser ([link removed])
[link removed]
** CURE Epilepsy Discovery
------------------------------------------------------------
[link removed]
** Advancing Toward Gene Therapies for Rare Epilepsies
------------------------------------------------------------
Read Article ([link removed])
As a young researcher in 2010, Dr. Mingshan Xue met Caroline DeLuca and her mother, Elizabeth. During their 20-minute talk, Caroline had three seizures — unfortunately frequent occurrences due to a mutation in one of her STXBP1 genes.
It made a lasting impression. When Xue established his lab in 2014 at Baylor College of Medicine to study the visual cortex, he established a side project investigating STXBP1 ([link removed]) , a mutation of which is very rare but is nonetheless considered one of the most common genetic causes of epilepsy.
“The only reason we started working on this is simply because I had met [Caroline], and I wanted to help,” Xue says. “I just thought I would do a small project to see what we could do about it.”
[link removed]
Ten years later that humble side project, with the help of funding from CURE Epilepsy, has developed into a potential curative treatment on the cusp of human clinical trials. Xue is now partnering with Capsida, a biotech company, to develop a gene therapy, CAP-002, that will supplement STXBP1 protein in the brain.
Learn About the Research ([link removed])
** Check Out The Latest:
------------------------------------------------------------
[link removed]
** Seizing Life Podcast ([link removed])
------------------------------------------------------------
[link removed]
** Epilepsy Explained ([link removed])
------------------------------------------------------------
Our mission is to fund breakthrough research that will transform the lives of people with epilepsy as we lead the search for a cure. CURE Epilepsy is a non-profit 501(c)(3) tax-exempt organization. Our tax identification number is 36-4253176.
Donate ([link removed])
[link removed]
[link removed]
[link removed]
[link removed]
[link removed]
[link removed]
[link removed]
Copyright (C) 2024 CURE Epilepsy. All rights reserved.
In the past you provided CURE Epilepsy your email address. Occasionally, you will receive updates from us about epilepsy research and news.
Our mailing address is:
CURE Epilepsy
420 Wabash Ave, Ste 650
Chicago, IL 60611
USA
Want to change how you receive these emails?
You can update your preferences ([link removed]) or unsubscribe ([link removed])
