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“Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices—United States, 2024–25 Influenza Season” published in MMWR
CDC published Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices—United States, 2024–25 Influenza Season on August 29 in MMWR Recommendations and Reports. A portion of the summary appears below.
All persons should receive an age-appropriate influenza vaccine (i.e., one approved for their age), with the exception that solid organ transplant recipients aged 18 through 64 years who are receiving immunosuppressive medication regimens may receive either high-dose inactivated influenza vaccine (HD-IIV3) or adjuvanted inactivated influenza vaccine (aIIV3) as acceptable options (without a preference over other age-appropriate IIV3s or RIV3). Except for vaccination for adults aged ≥65 years, ACIP makes no preferential recommendation for a specific vaccine when more than one licensed and recommended vaccine is available. ACIP recommends that adults aged ≥65 years preferentially receive any one of the following higher dose or adjuvanted influenza vaccines: trivalent high-dose inactivated influenza vaccine (HD-IIV3), trivalent recombinant influenza vaccine (RIV3), or trivalent adjuvanted inactivated influenza vaccine (aIIV3). If none of these three vaccines is available at an opportunity for vaccine administration, then any other age-appropriate influenza vaccine should be used.
Access the MMWR article in HTML or PDF.
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FDA authorizes updated protein-based Novavax COVID-19 vaccine for people age 12 years and older to better protect against currently circulating variants
On August 30, one week after approving the 2024–25 mRNA COVID-19 vaccines, FDA authorized use of the 2024–25 formulation of the protein-based Novavax COVID-19 vaccine. The new formulation contains a single antigen that corresponds to the Omicron variant JN.1 strain of SARS-CoV-2. Because the Novavax COVID-19 vaccine continues to be used only under the terms of an emergency use authorization (EUA), those who administer it should refer to the FDA’s updated EUA Fact Sheet for Healthcare Providers Administering Vaccine and provide recipients with FDA’s updated EUA Fact Sheet for Recipients and Caregivers. Novavax COVID-19 vaccine is authorized for use in people age 12 years and older.
At its June 2024 meeting, ACIP voted in advance to recommend use of 2024–25 COVID-19 vaccines in the manner licensed or authorized by FDA. Therefore, clinicians may begin using any of the 2024–25 COVID-19 vaccines as indicated by FDA as soon as they receive them. A portion of the recent FDA press release appears below.
What You Need to Know
- Individuals 12 years of age and older who have never been vaccinated with any COVID-19 vaccine are eligible to receive two doses of this updated [Novavax] vaccine, 3 weeks apart
- Individuals who have been vaccinated only with one dose of any Novavax COVID-19 vaccine are eligible to receive one dose of the updated Novavax COVID-19 vaccine at least 3 weeks after the previous dose
- Those who have been vaccinated with a prior formula of a COVID-19 vaccine from another manufacturer or with two or more doses of a prior formula of the Novavax COVID-19 vaccine are eligible to receive a single dose of the updated Novavax COVID-19 vaccine at least 2 months after the last dose of a COVID-19 vaccine
On August 23, CDC posted interim clinical considerations for COVID-19 vaccines for the current season. Immunize.org is in the process of revising our COVID-19 content. We will post online and announce in IZ Express new standing orders templates from CDC for the use of 2024–25 Novavax COVID-19 vaccine as soon as they are available. These updates are reflected in the September revision of Immunize.org’s Checklist of Current Versions of U.S. COVID-19 Vaccination Guidance and Clinic Support Tools.
Do not administer any remaining doses of any 2023–24 COVID-19 vaccine; if you have any, remove them from storage units and dispose of them or return them as appropriate.
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Immunize.org updates “Ask the Experts: RSV (Respiratory Syncytial Virus)” web section for the 2024–25 season
Immunize.org updated its popular Ask the Experts: RSV (Respiratory Syncytial Virus) web page to reflect the 2024 ACIP recommendations for RSV vaccination of older adults. Content has been updated to include the newest RSV vaccine, the mRNA vaccine, mResvia (Moderna). The content also now addresses the recently published updated ACIP recommendations for older adults, including the routine recommendation for one dose of RSV vaccine for all adults age 75 years or older and the recommendation for one dose of RSV vaccine for adults age 60 through 74 who are at increased risk of severe RSV disease.
Immunize.org’s Ask the Experts main page leads you to 30 web pages on various topics with more than 1,300 common or challenging questions and answers about vaccines and their administration. Immunize.org’s team of experts includes Kelly L. Moore, MD, MPH (team lead); Carolyn B. Bridges, MD, FACP; Iyabode Beysolow, MD, MPH; and Jane R. Zucker, MD, MPH.
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- Immunize.org: Ask the Experts main page with more than 1,300 questions and answers
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Immunize.org updates “Vaccinations for Adults: You’re Never Too Old to Get Vaccinated!” handout with current pneumococcal and RSV recommendations
Immunize.org updated its Vaccinations for Adults: You’re Never Too Old to Get Vaccinated! This handout now includes the recently updated recommendations for routine RSV vaccination of adults age 75 years and older, as well as risk-based recommendations for adults age 60–74 years. Information on pneumococcal vaccines was reworded for greater clarity.
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Immunize.org updates the Spanish translations of 2024–25 screening checklists for contraindications to injectable and nasal influenza vaccines
Immunize.org updated its Spanish translations of screening checklists for the 2024–25 influenza season.
References to the number of influenza virus strains in the vaccines were removed because all vaccines for this season contain three strains, two influenza A and one influenza B strain. The B/Yamagata strain is no longer included because it is not detected anywhere in the world.
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CDC’s Bridge Access Program to provide free COVID-19 vaccines to uninsured or underinsured adults ended
CDC’s Bridge Access Program to provide COVID-19 vaccination for uninsured or underinsured adults ended in August 2024 due to a loss of funding. Limited federal funds have been made available to state public health departments to support the purchase some of the 2024–25 updated COVID-19 vaccines for this population.
In the absence of the Bridge Access Program, uninsured adults seeking the 2024–25 COVID-19 vaccine should contact their state or local health department immunization programs for additional information about affordable access options in their area.
The 2024–25 COVID-19 vaccines remain accessible with no out-of-pocket cost through in-network vaccination providers to Medicaid and Medicare recipients and to adults with commercial insurance compliant with the Affordable Care Act. Children and teens younger than age 19 years who are uninsured or underinsured, or American Indian or Alaska Native, continue to have access to these vaccines at no cost through the federal Vaccines for Children program.
Watch and share the latest installment in Immunize.org’s Orientation Video Series: Introducing Immunize.org (mobile view) to see how our new mobile site looks on your smartphone!
Immunize.org is pleased to share a new version of Introducing Immunize.org, a 3-minute video introducing our website, that shows you how the new mobile version of the site looks on your smartphone. This video provides a quick overview of our organization, mission, website, and the resources we offer to support effective immunization practices.
Available now on our YouTube channel, this is part of our new Orientation Video Series. Each orientation video will be made available in a horizontal version (formatted for desktops) and a vertical version (for smart phones) to help you become familiar with the new look and navigation of the website.
Please share this video with anyone who needs to learn how to get the most out of Immunize.org’s website to support effective immunization practices.
Like, follow, and share Immunize.org’s social media accounts and encourage colleagues and others interested in vaccination to do likewise.
IZ Express keeps 54,000+ readers up to date on what’s new in vaccines each week; invite your colleagues to subscribe
Encourage your coworkers to subscribe to IZ Express so they get all the news that matters to vaccinators in their own inbox each Wednesday. IZ Express, the weekly e-newsletter produced by Immunize.org, alerts 54,000+ readers to the week’s important vaccine developments. IZ Express also features:
- Educational materials from Immunize.org, CDC, AAP, and others
- Newly posted VISs and their translations
- Notices about online and in-person educational opportunities, many offering free continuing education credit
We appreciate you as a subscriber! Thank you for helping us get the latest vaccine news to every clinical and public health professional who needs to know.
Journalists interview Immunize.org experts
Journalists seek out Immunize.org experts to help explain vaccines to the public and policy makers. We help the media understand and communicate the complex work vaccinators do. Here is a selection of our recent citations.
These recent articles convey the potential risks of vaccine-preventable diseases and the importance of vaccination.
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Immunize.org Website and Clinical Resources
Spotlight on the website: Ask the Experts video questions and answers
This week’s Spotlight features a new way to experience Ask the Experts questions and answers. Short videos recorded by Dr. Kelly Moore have been available for some time on our Videos page and our YouTube channel. Now these are integrated into the Ask the Experts section of our website and are searchable using the filter functions already available for our written content.
Each video includes a preview image linked to the full video. The video duration and a link to view all video questions is listed below the image. Currently, there are 36 Ask the Expert videos, and more will be added in the future.
In the Ask the Experts section of the website, video and traditional text question-and-answers are intermixed. Both can be viewed by topic or in the search and filter results. If you prefer only video results, use shortcuts to view only videos on the Ask the Experts main menu tab and left-side menu.
We hope you continue to find Ask the Experts to be a valuable resource and that these enhancements will help you more easily find relevant answers to your questions about vaccines and vaccine administration.
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Recap: Immunize.org updates “Ask the Experts: Influenza” web section for the 2024–25 influenza season
Immunize.org updated all the questions and answers on its popular Ask the Experts: Influenza web page. Clinical content now reflects 2024–25 influenza season recommendations. Changes include:
- References to the 2024–25 trivalent vaccines (containing two influenza A and one influenza B virus vaccine antigen) following removal of the B/Yamagata virus from the vaccine because it is no longer circulating
- Unless necessary for understanding, references to the number of strains in vaccines (also called “valency”) were removed
- ACIP affirmation that everyone age 6 months and older who has an egg allergy may receive any age-appropriate influenza vaccine without special precautions
- ACIP allowance for off-label use of high-dose (HD-IIV, Fluzone High-Dose, Sanofi) or adjuvanted influenza vaccine (aIIV, Fluad, CSL Seqirus) as an option for solid organ transplant recipients age 18 through 64 years who are on immunosuppressive medication regimens, without a preference over any other age-appropriate injectable influenza vaccine
- Updated hyperlinks, as needed
Immunize.org’s Ask the Experts main page leads you to 30 web pages on various topics with more than 1,300 common or challenging questions and answers about vaccines and their administration. Immunize.org’s team of experts includes Kelly L. Moore, MD, MPH (team lead); Carolyn B. Bridges, MD, FACP; Iyabode Beysolow, MD, MPH; and Jane R. Zucker, MD, MPH.
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- Immunize.org: Ask the Experts main page with more than 1,300 questions and answers
Recap: Immunize.org adds new PCV21 to “Ask the Experts: Pneumococcal” web section
Immunize.org updated all the questions and answers on its popular Ask the Experts: Pneumococcal web page. The clinical content now reflects updated recommendations for PCV21 vaccine (Capvaxive, Merck) as an option for adults age 18 years or older who are recommended to receive a pneumococcal conjugate vaccine. Hyperlinks were also updated as needed.
Immunize.org’s Ask the Experts main page leads you to 30 web pages on various topics with more than 1,300 common or challenging questions and answers about vaccines and their administration. Immunize.org’s team of experts includes Kelly L. Moore, MD, MPH (team lead); Carolyn B. Bridges, MD, FACP; Iyabode Beysolow, MD, MPH; and Jane R. Zucker, MD, MPH.
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- Immunize.org: Ask the Experts main page with more than 1,300 questions and answers
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Recap: Immunize.org adds new vaccines to popular resource “Before You Vaccinate Adults, Consider Their ‘H-A-L-O’!”
Immunize.org recently updated its resource for healthcare professionals titled Before You Vaccinate Adults, Consider Their “H-A-L-O”!
H-A-L-O refers to four factors:
- Health condition
- Age
- Lifestyle
- Occupation
The document now includes mpox vaccine and updated polio (IPV) vaccination recommendations for previously unvaccinated adults. The RSV vaccine section was revised to match the June 2024 ACIP recommendations for routine vaccination of adults age 75 years and older, and risk-based vaccination of adults age 60 through 74 years.
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Recap: Immunize.org updates “Vaccines with Diluents: How to Use Them” resource
Immunize.org recently added Penbraya (MenABCWY, Pfizer) to its Vaccines with Diluents: How to Use Them and updated the resource to specify the formulation of Pfizer-BioNTech COVID-19 vaccine that requires dilution.
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Featured Resources
Champions for Vaccine Education, Equity, and Progress releases “Stay Updated” campaign to explain the importance of receiving updated COVID-19 and influenza vaccines
Champions for Vaccine Education, Equity, and Progress (CVEEP), led by the Alliance for Aging Research, HealthyWomen, and the National Caucus and Center on Black Aging, released its Stay Updated campaign. This promotion highlights the importance of receiving updated COVID-19 and influenza vaccines this season. This campaign offers fact sheets, an informational poster, a glossary of virology terms, and an information sheet on milestones in COVID-19 vaccination.
Visit CVEEP's Stay Updated campaign to learn more about the need for updated vaccines and access resources to encourage your community to stay protected.
Explore the www.Give2MenACWY.org website to increase coverage for the meningococcal ACWY booster and other adolescent vaccinations
Immunize.org's www.Give2MenACWY.org website promotes the importance of adolescent vaccination, including the recommended MenACWY vaccine booster dose at age 16. Many teens are behind on vaccines because of the pandemic, so vaccine outreach is more important than ever.
Materials on this colorful website for healthcare professionals incorporate the 2020 ACIP meningococcal vaccine recommendations and coverage statistics from CDC’s National Immunization Survey–Teen (NIS–Teen). One particularly popular resource on the site is the Algorithm for MenACWY Immunization in Adolescents 11 through 18 Years of Age.
The website is divided into five easy-to-access sections:
The site also categorizes materials according to whether they are primarily of interest to providers, to adolescents, or to parents.
Visit Give2MenACWY.org and enjoy browsing (and deploying) its bountiful resources.
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Notable Publications
“Back to School Means Updating Childhood Vaccines” published in Clinical Advisor
In its August 23 issue, Clinical Advisor published Back to School Means Updating Childhood Vaccines. This article was written by Immunize.org’s Mary Beth Koslap-Petraco, DNP, FAANP. The introduction paragraph appears below.
The lazy, crazy days of summer are drawing to a close and it is time to start thinking about back to school and all that entails to prepare students to optimize their health. Vaccines can be number one on the list. We need to take a serious look at how the number of children who receive all necessary vaccines for school has dropped since the COVID-19 pandemic began its devastating march around the world. The immunization rates are even lower in children who are eligible for the Vaccines for Children (VFC) program. This federal program provides no-cost vaccines to children who are uninsured or are Medicaid eligible. In some states VFC also covers children whose insurance does not cover vaccines. It is time to review what vaccines are indicated to keep all students healthy and practice some infection prevention.
Upcoming Events
Virtual: Watch September 12–13 National Vaccine Advisory Committee meeting addressing hepatitis B, tuberculosis, and HIV vaccines
National Vaccine Advisory Committee (NVAC) meetings are held three times each year to address pressing topics affecting the vaccine enterprise. The September 12–13 NVAC agenda topics include implementation of the universal hepatitis B vaccine recommendations for adults age 19–59 years, new approaches for tuberculosis vaccine innovation, and research to inform future HIV vaccine development. NVAC will also host panels on vaccine equity, provider payment, and planning for the development of the next national vaccine strategy.
The hepatitis B panel will include Immunize.org CEO, Kelly L. Moore, MD, MPH, discussing challenges and opportunities to increase HepB coverage in adults.
NVAC meetings are open to the public and can be viewed virtually. Preregistration is required for both public attendance and comment.
View the September 12–13 NVAC Meeting web page for more information.
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