The Latest Epilepsy Research

CURE Epilepsy is dedicated to funding patient-focused research to find a cure for the 65 million people with epilepsy worldwide. This month, we share the following articles and abstracts which are furthering the study of epilepsy and bringing the world closer to a cure.

Genetic ‘Episignatures’ Guide Researchers in Identifying Causes of Unsolved Epileptic Neurological Disorders


Scientists at St. Jude Children’s Research Hospital demonstrated the value of DNA methylation patterns for identifying the root cause of developmental and epileptic encephalopathies (DEEs). Their new study shows that specific gene methylation and genome-wide methylation “episignatures” can help identify the genes that cause DEE. DEEs affect 1 in 590 children and involve more than 825 genes. 

Children's Hospital of Philadelphia Researchers Use AI-Powered Method to Identify Genetic Epilepsies Much Earlier than Genetic Diagnosis


Researchers at the Epilepsy Genetics Initiative (ENGIN) at Children's Hospital of Philadelphia (CHOP) used machine learning and artificial intelligence to comb through medical records and use clinical notes to match symptoms with specific genetic epilepsies. Building upon previously developed techniques, the researchers aimed to identify early clinical features that could suggest a genetic diagnosis of epilepsy. 

University of Virginia Research Provides Better Understanding of Alzheimer’s, Epilepsy


Researchers from the University of Virginia School of Medicine have discovered functions of structures in the brain that could help understand and treat several neurological disorders.

Brain Activity Patterns Can Foreshadow 24-Hour Seizure Risk


A team of epilepsy specialists at University of California San Francisco has developed a method to predict 24-hour seizure risk. The researchers, led by Vikram Rao, MD, PhD, a Distinguished Professor in Neurology, showed that the storm of brain activity characterizing a seizure is presaged by abnormal communication between specific areas of the brain.

Propofol Shows Potential for Treating Epilepsy and Neurological Disorders


According to a new study led by researchers at Weill Cornell Medicine and Linköping University in Sweden, the general anesthetic propofol may hold the keys to developing new treatment strategies for epilepsy and other neurological disorders.

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