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Issue 1,763: June 26, 2024

Top Stories
* Watch and share the new 3-minute video introduction to Immunize​.org and its resources
* Immunize​.org posts revised versions of four Chinese translations of VISs for varicella-containing vaccines
* FDA licenses Merck’s new 21-valent pneumococcal conjugate vaccine (PCV21) for adults; ACIP to consider recommendations for use this week
* Canada Day is July 1! Here’s a summary of vaccination information and advocacy in Canada.
* Should live vaccines be given to a healthy child whose mother is getting cancer chemotherapy? Watch the 3-minute answer, part of the Ask the Experts Video Series on YouTube.
* Vaccines in the news


Immunize​.org Website and Clinical Resources
* Spotlight on the website: Looking for a past IZ Express article? Here’s how to browse all issues.


Featured Resources
* Association of Immunization Managers shares six new e-learning modules for vaccinators and community vaccine champions, with updated guide, Connecting the Dots: Vaccine Confidence

Notable Publications
* "Effects of HPV Vaccination on the Development of HPV-Related Cancers: A Retrospective Analysis of a United States-Based Cohort." published in Journal of Clinical Oncology


Upcoming Events
* Today: Virtual: Watch June 26–28 ACIP meeting with wide-ranging discussion on vaccine preventable diseases
* In-person: Registration open for CDC’s 49th National Immunization Conference on August 12–14 in Atlanta; CE credit offered
* Virtual: CDC hosts COCA call "Mpox Update: Clinical Management and Outbreaks" on June 27 at 2:00 p.m. (ET); CE credit offered


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Top Stories
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Watch and share the new 3-minute video introduction to Immunize​.org and its resources

Immunize​.org is delighted to share a new, 3-minute online video introducing our organization and the resources available on our website. The video is available now on our YouTube channel ([link removed]) as the first in a new orientation series of quick 3-minute videos designed to help both new and experienced users become more familiar with our new website and get the most out of all the resources we offer. Each new orientation video will be featured in IZ Express as it is released. Horizontal versions of these videos, like this one, will orient viewers to the desktop format of the website; later vertical versions of the videos will feature the mobile format of the site.

Please share this video with your colleagues and trainees, and anyone else who should know more about Immunize​.org and how we can support effective immunization practices.
Back to top (#Top)
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Immunize​.org posts revised versions of four Chinese translations of VISs for varicella-containing vaccines

At the recommendation of an alert Chinese-speaking reader, Immunize​.org requested the removal of Chinese characters included parenthetically in the document title of varicella-containing vaccine VISs as a synonym to the Chinese characters used throughout the document to refer to varicella or chickenpox. These parenthetical characters refer broadly to pox viruses and do not refer exclusively to “chickenpox.” To avoid any confusion, these characters in parentheses were removed from the titles. The VISs are dated August 6, 2021.

Varicella (Chickenpox) Vaccine VIS ([link removed])
* Chinese–Simplified ([link removed])
* Chinese–Traditional ([link removed])

MMRV (Measles, Mumps, Rubella, Varicella) Vaccine VIS ([link removed])
* Chinese–Simplified ([link removed])
* Chinese–Traditional ([link removed])

To ensure you have the current translations, click on Vaccines & VISs at Immunize​.org, then click on VISs, then select a specific vaccine. Scrolling down the resulting page, you will see the current English version, a list of current translations (i.e., corresponding to the current English VIS), and then, if applicable, a list of any out-of-date (yet best available) translations. Additional tips on using VISs appear at the bottom of the page.

Related Links
* Immunize​.org: Vaccine Information Statement ([link removed]) main page for VISs in 47 languages ([link removed])
* Immunize​.org: Dates of Current Vaccine Information Statements ([link removed]) (PDF)
* CDC: What's New with VISs ([link removed]) web page
* CDC: Current VISs ([link removed]) web page

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FDA licenses Merck’s new 21-valent pneumococcal conjugate vaccine (PCV21) for adults; ACIP to consider recommendations for use this week

On June 17, FDA licensed Capvaxive (Merck), a 21-valent pneumococcal conjugate vaccine (PCV21), for use in adults age 18 years and older. This PCV21 targets several serotypes not included in other PCV brands that cause serious pneumococcal disease more often in adults than in children. It does not include certain serotypes in the PCV brands recommended for children.

The CDC’s ACIP will review available data on its safety and effectiveness and consider recommendations for its use this week.

The package insert ([link removed]) and approval letter ([link removed]) are available from FDA.

Related Link
* FDA: Capvaxive product information ([link removed]) web page

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Canada Day is July 1! Here’s a summary of vaccination information and advocacy in Canada.

O, Canada! Recognizing Canada’s 156th national anniversary on July 1, we are sharing select Canadian vaccination resources. Happy Canada Day to the vaccination providers and champions among our readers in Canada!

Expert committees:
* National Advisory Committee on Immunization (NACI) ([link removed]), counterpart to ACIP
* Committee to Advise on Tropical Medicine and Travel (CATMAT) ([link removed])

Advocacy groups:
* CANVax ([link removed]) (Canadian Vaccination Evidence Resource and Exchange Centre): search through their library of resources (curated by the Canadian Public Health Association ([link removed]))
* Immunize Canada ([link removed]): a national coalition of nongovernmental, professional, health, government, and private sector organizations with a specific interest in promoting the understanding and use of vaccines recommended by NACI
* Canadian Nurses Association ([link removed])

Helpful resources:
* Canadian Immunization Guide ([link removed]), counterpart to CDC’s "The Pink Book"
* Canadian Communicable Disease Report (CCDR) ([link removed]), counterpart to MMWR
* Canadian Adverse Events following Immunization Surveillance System (CAEFISS) ([link removed])
* Public Health Agency of Canada (PHAC)
+ Immunization and vaccine awareness materials ([link removed]) (PDFs, videos)
+ Immunization Competencies for Health Professionals ([link removed])
* Canadian Paediatric Society: Education Program for Immunization Competencies (EPIC) ([link removed])
* Provincial and Territorial Routine and Catch-Up Vaccination Schedule for Infants and Children in Canada ([link removed])
* Provincial and Territorial Routine Vaccination Programs for Healthy, Previously Immunized Adults ([link removed])
* HELPinKids&Adults ([link removed]) : organization offering resources to make the vaccination experience more positive for everyone
* CARD System ([link removed]) (Comfort, Ask, Relax, Distract): strategies that will help to provide a better vaccination experience

COVID-19 resources:
* Health Canada: Vaccine Authorizations for COVID-19 ([link removed])
* Public Health Agency of Canada: COVID-19 ([link removed])

Government links:
* Health Canada ([link removed]), counterpart to HHS
* Public Health Agency of Canada (PHAC) ([link removed]), counterpart to CDC
* Health Products and Food Branch (HPFB) ([link removed]), counterpart to FDA
* Drug Product Database online query ([link removed]): list of drugs and vaccines permitted to be distributed within Canada, corresponding to licensed or approved status in the United States

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Should live vaccines be given to a healthy child whose mother is getting cancer chemotherapy? Watch the 3-minute answer, part of the Ask the Experts Video Series on YouTube.

This week, our featured episode from the Ask the Experts Video Series addresses the question of whether to administer live virus vaccines to a household member of someone going through cancer chemotherapy ([link removed]). The video highlights the importance of vaccinating household contacts and other close contacts of people who are immunocompromised.

The 3-minute video is available on our YouTube channel ([link removed]), along with our full collection of quick video answers to popular Ask the Experts ([link removed]) questions.

Like, follow, and share Immunize​.org’s social media accounts and encourage colleagues and others interested in vaccination to do likewise.
* Facebook at ImmunizeOrg ([link removed])
* Instagram at ImmunizeOrg ([link removed])
* LinkedIn at ImmunizeOrg ([link removed])
* YouTube at ImmunizeOrg ([link removed])

Related Link
* Immunize​.org: Ask the Experts: Contraindications ([link removed])

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Vaccines in the news

These recent articles convey the potential risks of vaccine-preventable diseases and the importance of vaccination.

* STAT: Telling New Stories Can Help People See the Value of Vaccines ([link removed]) (6/14/24)

* CIDRAP: Misleading BMJ Public Health Paper on COVID-19 Excess Mortality Needs to Be Retracted ([link removed]) (Commentary) (6/17/24)


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Immunize​.org Website and Clinical Resources
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Spotlight on the website: Looking for a past IZ Express article? Here’s how to browse all issues.

This week, we focus on how to access any of the 1,762 past issues of IZ Express (known from 1997 through 2022 as IAC Express).

The back issue archive is available from the “News & Updates” menu tab within the “IZ Express Newsletter” section through the “Browse All Issues” link.

The tables of contents for back issues are listed in date order with the most recent shown first. Within each issue, simply click on any title in the table of contents to read the full story. View a complete issue by selecting the “Read full issue” link located to the right of the title.

You can search and filter issues to find specific topics of interest. To search, type keyword(s) in the search box (“Search & Filters” button on mobile devices), then select the “Search” button. Issues matching your criteria will be returned with the search terms highlighted. Results can also be filtered by date by selecting a year and month from the filter options.

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Featured Resources
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Association of Immunization Managers shares six new e-learning modules for vaccinators and community vaccine champions, with updated guide, Connecting the Dots: Vaccine Confidence

The Association of Immunization Managers ([link removed]) (AIM) iREACH team ([link removed]) created a series of six e-learning modules ([link removed]) to help support anyone who engages in community conversations about influenza, COVID-19, and vaccine safety. These free modules also address racial and ethnic disparities in vaccine coverage and disease outcomes and how to close these gaps.

* Audience: these modules were created with community health workers, promotoras (trusted messengers), and community champions in mind
* Settings: the modules can be used for individual or shared learning
* Certificate of completion: available
* Languages: English and Spanish
* Formats: desktop, tablet, or cell phone

View the modules ([link removed]).

Additionally, AIM updated its 1-page guide, Connecting the Dots: Vaccine Confidence ([link removed]). This resource organizes links to vaccine confidence tools in three categories: effective communication, health equity, and addressing misinformation. Each category includes information for immunization program managers and their partners.

Visit AIM's All Resources and Tools ([link removed]) main page for more.

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Notable Publications
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"Effects of HPV Vaccination on the Development of HPV-Related Cancers: A Retrospective Analysis of a United States-Based Cohort." published in Journal of Clinical Oncology

In the May 29 issue, Journal of Clinical Oncology published a meeting abstract Effects of HPV Vaccination on the Development of HPV-Related Cancers: A Retrospective Analysis of a United States-Based Cohort ([link removed]). This study linked vaccination data and cancer diagnosis data for patients age 9–39 years. Patients vaccinated or unvaccinated for HPV were compared.

* Males vaccinated for HPV (n = 760,540) had 54% lower odds of developing HPV-related cancers (especially head and neck cancers)
* Females vaccinated for HPV (n = 945,999) had close to 30% lower odds of developing cervical cancers and any HPV-related cancer

These results add to the evidence of HPV vaccine’s real world effectiveness in preventing several types of cancer and precancerous changes caused by HPV.

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Upcoming Events
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Today: Virtual: Watch June 26–28 ACIP meeting with wide-ranging discussion on vaccine preventable diseases

CDC convenes its ACIP ([link removed]) June 26–28, starting at 8:00 a.m. (ET). ACIP will discuss vaccines to prevent chikungunya, dengue, COVID-19, influenza, pneumococcal, meningococcal, RSV, and HPV. Anticipated votes are expected to have an impact on the practices of many vaccination providers.

Look for our meeting report, highlighting ACIP’s votes on new or updated recommendations, in the July 3 edition of IZ Express.

No registration is required to watch webcasts of live ACIP meetings or listen via telephone.

View the agenda ([link removed]).

Related Links
* CDC: ACIP main page ([link removed]) for access to webcast, agendas
* CDC: ACIP: Meeting Information ([link removed]) for presentation slides, content from previous meetings, and information about future meetings

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In-person: Registration open for CDC’s 49th National Immunization Conference on August 12–14 in Atlanta; CE credit offered

CDC will host National Immunization Conference 2024 ([link removed]) on August 12–14 in Atlanta, GA. Program content will cover science, policy, education, and implementation issues related to immunization and vaccine-preventable diseases.

Registration is now open. The general attendee fee is $685. CE will be offered. Register for the conference ([link removed]).

If you attend, be sure and find the team at Immunize​.org’s exhibit booth and say hello!

See CDC's National Immunization Conference 2024 ([link removed]) website for more information.

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Virtual: CDC hosts COCA call "Mpox Update: Clinical Management and Outbreaks" on June 27 at 2:00 p.m. (ET); CE credit offered

CDC will host a Clinician Outreach and Communication Activity (COCA) call titled Mpox Update: Clinical Management and Outbreaks ([link removed]), 2:00–3:00 p.m. (ET) on June 27. During this COCA call, presenters will give updates on the mpox clade I outbreak in the Democratic Republic of the Congo (DRC) and remind clinicians to be alert for mpox in patients with recent travel to the DRC. Discussion will address when to suspect a case of mpox, clinical management and prevention of clade II mpox, and recent mpox vaccination data.

Presenters will also discuss expanded availability to mpox vaccine (Jynneos, Bavarian Nordic) as the vaccine becomes commercially available, in addition to antiviral treatment options.

A recording of the presentation will be archived for viewing on the COCA call web page ([link removed]) a few hours after the live event ends.

Free continuing education credit (CME, CPE, CNE, and other) will be offered for this COCA call. Registration is not required.

Link for the June 27 call ([link removed]).

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For more upcoming events, visit our Calendar of Events ([link removed]).

Editorial Information
Editor-in-Chief
Kelly L. Moore, MD, MPH

Managing Editor
John D. Grabenstein, RPh, PhD

Associate Editor
Sharon G. Humiston, MD, MPH

Writer/Publication Coordinator
Taryn Chapman, MS
Courtnay Londo, MA

Style and Copy Editor
Marian Deegan, JD

Web Edition Managers
Arkady Shakhnovich
Jermaine Royes

Contributing Writer
Laurel H. Wood, MPA

Technical Reviewer
Kayla Ohlde

About IZ Express
Immunize​.org welcomes redistribution of this issue of IZ Express or selected articles.
When you do so, please add a note that Immunize​.org is the source of the material and provide a link to this issue ([link removed]).

IZ Express is supported in part by Grant No. 1NH23IP922654 from the National Center for Immunization and Respiratory Diseases, CDC. Its contents are solely the responsibility of Immunize​.org and do not necessarily represent the official views of CDC.

IZ Express Disclaimer ([link removed])
ISSN: 2771-8085

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