 | From the Editor's Desk
Does Long-Term Benadryl Use Increase Dementia Risk? - Scientific American (No paywall) In the past few months TikTok videos about the over-the-counter antihistamine Benadryl have gone viral because of research suggesting that long-term use of the popular drug is associated with an increased risk of developing dementia. And similar effects on memory and cognition have also been suggested for dozens of other common medications.
Benadryl is a brand-name medication that contains diphenhydramine, the active ingredient in many allergy, cold and anti-itch drugs. It can cause significant drowsiness and is also found in several sleep aids. Diphenhydramine has anticholinergic effects, meaning it blocks the action of a neurotransmitter called acetylcholine. Medical uses of anticholinergics go beyond allergy relief; drugs in this class have long been used as prescription tricyclic antidepressants and incontinence treatments, as well as over-the-counter sleep aids. But experts have been finding evidence that links anticholinergics to increased dementia risks. “That’s now clear, and we have plenty of data to back it up,” says Malaz Boustani, a geriatrician and neuroscientist at the Indiana University School of Medicine. He and other researchers are now trying to determine whether anticholinergics really are contributing to dementia development in any way—and if so, what exactly is happening in the brains of vulnerable adults.
Continued here
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WorkWorkGaza is on the brink of a man-made famine - The Economist (No paywall)
  Try our new AI-powered search.css-1mui2f{background-color:var(--ds-color-new-york-90);box-sizing:border-box;color:var(--ds-color-london-5);font-family:var(--ds-type-system-sans-smallcaps);font-style:normal;font-size:0.9375rem;font-weight:500;margin-left:0.5rem;padding:0.125rem 0.5rem;}beta WorkWorkWorkWorkWorkWorkWorkWorkWorkWorkNinja, Video Gaming Star on Twitch, Reveals Skin Cancer Diagnosis
 William Dahut, the American Cancer Society’s chief scientific officer, said on Wednesday that a melanoma found on the palms of the hands, the soles of the feet or beneath the fingernails “is a rare type.” He suggested that people use sunscreen and frequently check their skin, and consult a dermatologist if anything suspicious is found. WorkWorkWorkState department official's resignation highlights rifts over US Gaza policy
 "Not only are these policies devastating the people of Gaza, but I think they're also devastating the US image in the world," she argued. "This administration came in promising to rebuild American diplomacy and America's moral leadership after the Trump administration, but so many of these issues that the administration said were so important - including human rights - seem to be less important to this administration than the US-Israel relationship." WorkWorkWorkWorkHow a viral $22 burrito explains inflation in the US
 Ricardo Lopez’s taqueria is famous for a melt-in-your-mouth birria recipe that takes three days to prepare. Every week, hundreds of customers flock to La Vaca Birria in San Francisco’s Mission District for a taste of the slow-braised beef served over rice and beans or tucked into a crispy taco with a side of rich dipping broth. WorkWorkWorkThe Guardian view on Evan Gershkovich's year behind bars: Moscow should free him now | Editorial
 Evan Gershkovich, a Wall Street Journal reporter, has spent nearly a year in a Moscow prison, awaiting trial for a crime he did not commit. Mr Gershkovich was arrested last March in the Urals city of Yekaterinburg and jailed on espionage charges. He is not a spy. He is a journalist, and should be released immediately. Hostage diplomacy lies behind his incarceration. As the US ambassador to Russia, Lynne Tracy, said, Mr Gershkovich's case "is not about evidence, due process, or rule of law. It is about using American citizens as pawns to achieve political ends". WorkWorkWorkWorkWorkWorkWorkWorkWorkWorkWorkWorkWorkWorkWorkWorkWorkWorkWorkWorkWorkWorkWorkWorkWorkWorkEaster holiday travel warning
 Trade body Airlines UK said the whole sector had been \"investing in resilience and adjusting operations\" to make sure it could \"mitigate the impact of external factors for the millions of customers we look forward to carrying... across the busy summer season\". WorkWhat passes through Baltimore's port? Pretty much everything
 \"The collapse of the Key Bridge is not just a Maryland crisis, the collapse of the Key Bridge is a global crisis,\" Maryland Governor Wes Moore said on Wednesday. \"The national economy and the world\'s economy depends on the Port of Baltimore.\" WorkWhy the Solar Eclipse Will Not Leave People Without Power
 Although solar power produces only when the sun shines, forecasters can generally predict pretty well how much electricity panels will produce on any given day depending on the weather. That helps utility and grid managers make sure they have other sources of energy available to meet consumer needs. WorkDisney Ends Its Fight With DeSantis Over Resort Development
 “A year ago people were trying to act like all these legal maneuvers were all going to succeed, and the reality is here we are a year later, not one of them has succeeded,” Mr. DeSantis told reporters in Orlando. “Every action that we’ve taken has been upheld in full, and the state is better off for it.” WorkWorkWorkMany People and Companies Have Made Millions on Trump Media’s Stock
 The biggest beneficiary is Mr. Trump, the company’s largest shareholder, whose stake is worth more than $5 billion, on paper. No other shareholder comes close, according to regulatory filings, but many of Trump Media’s executives have seen their net worth swell this week, in some cases by many millions of dollars. WorkStephen Adams, Who Made Yale Music School Tuition-Free, Dies at 86
 In that same article, Michael Friedmann, a professor of theory and chamber music, said, “Musicians, as opposed to doctors or lawyers, are not in a position to repay educational loans easily, and the profession has a capricious opportunity structure.” He added, “The new financial conditions at the school, however, put musicians in a very different position in relation to their post-Yale careers.” TradeBriefs Publications are read by over 10,00,000 Industry Executives About Us | Advertise Privacy Policy | Unsubscribe (one-click) You are receiving this mail because of your subscription with TradeBriefs.
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