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CEO Picks - The best that international journalism has to offer!  S7The tech industry canât agree on what open-source AI means. Thatâs a problem. - MIT Technology Review (No paywall)   On the face of it, open-source AI promises a future where anyone can take part in the technology’s development. That could accelerate innovation, boost transparency, and give users greater control over systems that could soon reshape many aspects of our lives. But what even is it? What makes an AI model open source, and what disqualifies it?Entering this fray is the Open Source Initiative (OSI), the self-appointed arbiters of what it means to be open source. Founded in 1998, the nonprofit is the custodian of the Open Source Definition, a widely accepted set of rules that determine whether a piece of software can be considered open source.
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S42The EU Targets Apple, Meta, and Alphabet for Investigations Under New Tech Law ![]() Apple is among three tech giants being investigated for failing to comply with the European Union's new competition rules, in another blow to the embattled smartphone maker.Apple was the primary focus of an EU press conference on Monday morning. But authorities also opened formal investigations into Meta and Alphabet, Google's parent company. The trio are the first to be subject to formal probes under the EU's new Digital Markets Act, the bloc's landmark competition law, which took effect on March 7.
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S6The next generation of mRNA vaccines is on its way - MIT Technology Review (No paywall)  I can hear the collective groan from here, but wait—hear me out! I know you’ve heard a lot about mRNA vaccines, but Japan recently approved a new one for covid. And this one is pretty exciting. Just like the mRNA vaccines you know and love, it delivers the instructions for making the virus’s spike protein. But here’s what makes it novel: it also tells the body how to make more mRNA. Essentially, it provides instructions for making more instructions. It’s self-amplifying.Self-amplifying RNA vaccines (saRNA) offer a couple of important advantages over conventional mRNA vaccines, at least in theory. Because saRNA vaccines come with a built-in photocopier, the dose can be much lower. One team of researchers tested both an mRNA vaccine and an saRNA vaccine in mice and found that they could achieve equivalent levels of protection against influenza with just 1/64th the dose. Second, it’s possible that saRNA vaccines will induce a more durable immune response because the RNA keeps copying itself and sticks around longer. While mRNA might last a day or two, self-amplifying RNA can persist for a month.
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S12Is Crypto Cleaning Up Its Act? - Harvard Business Review (No paywall)  This article argues that markets in crypto-assets such as Bitcoin are maturing. This is partly due to firmer regulation and a greater willingness of crypto-asset creators to accept existing regulation. But there is also evidence that innovative moves by crypto-asset issuers to create new vehicles for investment in crypto-assets have improved price efficiency and market liquidity, making investment in crypto-assets safer for investors.
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S23Why an Up-and-Coming Wellness Brand Raised Debt Capital to Fuel Its Growth  The former Wall Streeter launched Lorton, Virginia-based Apothékary in 2018. The herbal medicine company recently closed an equity funding round, comprising $5 million in equity and $3 million in debt. That money will help the 50-person company grow its line of herbal remedies, which include wellness powders, tinctures, and teas. To date, the company has raised $13.5 million in equity and $4.25 million in debt."This marks our fifth year of business," says Okusa, "and while we're still just getting started, our volumes and profitability allow us to raise debt capital, or non-dilutive financing, to continue our growth." She told Inc. exactly how non-dilutive financing works, why it was the smart decision for her company, how she approached her most recent fundraise and how Apothékary plans to use the capital to fuel its future growth.
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S4312 Best Couches You Can Buy Online (2024): Sectionals, Sofas, Sleepers, and More ![]() If you buy something using links in our stories, we may earn a commission. This helps support our journalism. Learn more. Please also consider subscribing to WIREDMaybe you have a hand-me-down couch or a thrifted floral confection that isn't cutting it. Or maybe your seat cushions are sunken in and worse for wear. If you need a new sofa, you've come to the right place. A few of us here on the WIRED Gear team have spent several months testing a batch of couches you can order onlineâno need to leave the house. These are our favorites.
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S44Sci-Fi Author Vernor Vinge, Who First Wrote of the AI Singularity, Dead at 79 ![]() On Wednesday, author David Brin announced that Vernor Vinge, sci-fi author, former professor, and father of the technological singularity concept, died from Parkinson's disease at age 79 on March 20, 2024, in La Jolla, California. The announcement came in a Facebook tribute where Brin wrote about Vinge's deep love for science and writing."A titan in the literary genre that explores a limitless range of potential destinies, Vernor enthralled millions with tales of plausible tomorrows, made all the more vivid by his polymath masteries of language, drama, characters, and the implications of science," wrote Brin in his post.
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S8When Your Business Needs a Second Growth Engine - Harvard Business Review (No paywall)  Traditionally, the most reliable way for a firm to find its next wave of growth was to apply the capabilities of its core business in an adjacent market. But recently a new pattern has begun to emerge. More firms are learning the art of building large second cores—what Bain’s Zook and Allen call engine twos. Given that in the past five years, 60% of big public companies have seen their growth stall out or stagnate—often because of technological disruption—finding an engine two has become increasingly imperative.What does it entail? Successful engine twos have four factors in common: They target markets where the profit pool is sizable and growing or shifting, as Amazon’s cloud computing business did. They have a differentiated competitive advantage, which is often built up through acquisitions, as happened at Disney+. They adopt entrepreneurial approaches, like Bradesco’s digital unit, Next, and leverage the scale and assets of the original core, as the industrial cleaning company Ecolab’s new water-purification business did.
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S9A New Generation of Drug Therapies Requires New Business Strategies - Harvard Business Review (No paywall)  The shift to advanced therapeutic modalities (ATMs) promises to change the nature of competition in the pharmaceuticals industry. ATMs include engineered cell therapies that reprogram cells to fight disease, gene therapies that involve replacing or editing dysfunctional genes, and nucleic acid therapies that promote or shut down production of a protein. They are shifting the nature of drug R&D risk and establishing manufacturing as a critical strategic priority alongside therapeutic safety and efficacy while also introducing new commercialization challenges.The life sciences industry is undergoing a fundamental evolution in how drugs are discovered, developed, and manufactured. The industry is shifting from traditional drug research and development techniques used for small molecules and antibodies to advanced therapeutic modalities (ATMs), a category that encompasses engineered cell therapies that reprogram cells to fight disease, gene therapies that involve replacing or editing dysfunctional genes, and nucleic acid therapies that promote or shut down production of a protein (e.g., the mRNA vaccines indicated for Covid-19 from Moderna and Pfizer/BioNTech).
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S10The Challenge of Retaining Startup Talent After an Acquisition - Harvard Business Review (No paywall)  In the last two decades, the startup world has witnessed a steady climb in acquisitions. These acquisitions have emerged as the primary channel through which ventures successfully exit. It’s no surprise, given that acquisitions offer acquiring companies access to a new source of technological innovation, fresh talent, and increased market power. Among the most prized assets of many startup companies is their human capital, often serving as the driving force behind their innovation and success.
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S11How to Market Sustainable Products - Harvard Business Review (No paywall)  Many companies overestimate customers’ appetite for sustainable products, flooding the market with offerings that don’t sell. The reality is, social and environmental benefits have less impact on purchasing decisions than basic product attributes do. Consumers buy products to get specific jobs done, and only after they find something that will do that will they look for a product that provides some social or environmental advantage.Of course, that’s only if they value sustainability. Not everyone does, and marketers need to recognize that. Some customers (greens) place a premium on it, some (blues) value it only moderately, and some (grays) don’t care about it and view it skeptically. The three segments cannot all be approached in the same way. How sustainable product benefits interact with traditional benefits is also critical: They can have no impact on a product’s performance (independence), diminish it (dissonance), or enhance it (resonance). Marketers need to follow different playbooks for independent, dissonant, and resonant products, tailoring their approaches to green, blue, and gray customers with each.
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S5Tackling long-haul diseases - MIT Technology Review (No paywall)  It was 2017, and she was a Stanford postdoc exploring connections between her immune regulation research and immuno-oncology, which harnesses the body’s immune system to combat cancer. Her work focused on how healthy cells broadcast “Don’t eat me” messages while cells that are cancerous or infected with a pathogen send self-sacrificing “Eat me” messages. Immune cells, in turn, receive these missives in pocket-like receptors. The receptor that receives the healthy cells’ signal, Tal read as she was poring over the literature that day, is the third most diverse protein in the human population, meaning that it varies a lot from one person to the next. It was a fact that struck her as “very odd.” Tal, who has been obsessed with infectious disease since losing an uncle to HIV/AIDS and a cousin to meningococcal meningitis, wondered what this striking diversity could reveal about our immune response to infection. According to one hypothesis, the wide array of these receptors is the result of an evolutionary arms race between disease-causing microbes and the immune system. Think of the receptor as a lock, and the “Nothing to see here” message as a key. Pathogens might evolve to produce their own chemical mimics of this key, effectively hiding from the immune system in plain sight. In response, the human population has developed a wide range of locks to frustrate any given impostor key.
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S13S145 best exercises for building upper-body muscle when you're short on time at the gym, according to a top coach - Business Insider (No paywall)  Being absolutely jacked seems to be a prerequisite for playing a lead male role in movies, and that muscle-obsessed culture has trickled down to public gyms. It makes sense, then, that the global protein-supplement market is expected to be worth $38.36 billion by 2029, according to Precedence Research's estimate.If you're newer to the movement, a push-up is a great way to work the chest as well as the core and scapula muscles, and you can work your way up from push-ups on the knees to full-body ones. Once you can easily do sets of, say, 15 push-ups, it's time to increase the challenge by transitioning to chest presses.
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S19Why the CEO of Quantcast is betting on "personalized AI"  There’s a new startup in San Francisco, and they’re into marketing. Alone, that wouldn’t be so interesting, but this company has made its business about “algorithmic marketing.” This is 2006, in the days when Facebook was still new and generative artificial intelligence was a conversation among science fiction fans. But this startup is sure that machine learning is the future.The startup secures a major client, a local tourist board, and is eager to turn this into an early win. So they put their heads together and burned the midnight oil. Why would you come to San Francisco? Who should they target, and how? The team came up with the old, familiar answers: Alcatraz, Golden Gate Bridge, and wine country. But then they turned to their algorithm to measure the decision-making behaviors of potential San Francisco visitors.
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S25These Small Businesses Adopted 4-Day Workweeks. Here's What They Learned  While lawmakers and academic experts debate the pros and cons of a four-day workweek, many small businesses have already made the leap without cutting pay - and they say they're not going back. They are finding that a better work-life balance is good for business. Inc. talked to small businesses that already adopted this setup for about a year, or in the case of Tones of Melanin, a Black-owned sportswear company based in Norfolk, Virginia, for four years. They all said their teams remained productive even with a shorter work week and in fact found it helped avoid burnout.Â
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S45Chinese Hackers Charged in Decade-Long Global Spying Rampage ![]() For years, China's state-backed hackers have stolen huge troves of company secrets, political intelligence, and the personal information of millions of people. On Monday, officials in the United States and United Kingdom expanded the long list of hacking allegations, claiming China is responsible for breaching the UK's elections watchdog and accessing 40 million people's data. The countries also issued a raft of criminal charges and sanctions against a separate Chinese group following a multiyear hacking rampage.In August last year, the UK's Electoral Commission revealed "hostile actors" had infiltrated its systems in August 2021 and could potentially access sensitive data for 14 months until they were booted out in October 2022. The deputy prime minister, Oliver Dowden, told lawmakers on Monday that a China state-backed actor was responsible for the attack. In addition, Dowden said, the UK's intelligence services have determined that Chinese hacking group APT31 targeted the email accounts of politicians in 2021.
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S35Why Some Companies Grow Amid Uncertainty -- and Others Don't  When you cannot base strategy on reasonably certain premises — or when those reasonable premises are undone by unforeseeable events — what is a company to do? You still have to make plans, allocate capital, and invest for the future. Some argue that agility is the key to thriving in disruptive times, but if all you do is pivot, you are just going around in circles. The annual AlixPartners Disruption Index surveys 3,000 global executives about what is knocking them sideways. Among other things, it shows that three out of five say that it is increasingly challenging to know which disruptive forces to prioritize. Amid all this, there is a group of companies doing very well: about one in five said their companies lead their industry in revenue growth. In this article, the authors dig into that 2024 data to find out what sets these companies apart, and what other companies can learn from them about setting growth strategy in an uncertain world.
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S30Why Are So Many Brands Hitting the Road This Year?  But that didn't stop Lindsay Goodstein and Charlotte Cruze from doing just that last April. The co-founders of Alice Mushrooms launched their functional (non-psychedelic) mushroom brand in October 2022. To drum up sales, the co-founders rented a 1969 Chevrolet ice cream truck for a month in April 2023, and drove around California, stopping in their home-base, Venice, Santa Monica, downtown Los Angeles, Culver, Malibu and ending outside the Coachella festival in Indio, California. Cruze says a road trip is something she would "definitely recommend a young brand do." It's a great way to overcome consumer skepticism around businesses they only see marketed online, especially a mushroom chocolate brand, she adds. Using the truck to meet customers in person helped validate the brand's legitimacy, educate customers about both the business and science behind their chocolates, create viral marketing moments, and boost sales.
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S16Have McKinsey and its consulting rivals got too big? - The Economist (No paywall)  The memo, which was swiftly taken down, is but the latest murmur of discontent at McKinsey. In January Bob Sternfels, its managing partner, was forced into an internal contest for the top job after he failed to clinch support for re-election from a majority of senior partners in an initial round of voting. Although he ultimately prevailed, the saga hinted at the trouble brewing within the firm.
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S17Sleep Better at Every Age  The amount of sleep a person needs recalibrates over time, and circadian rhythms change with age. The 16-year-old who stayed up until midnight may become a 36-year-old who gets drowsy by 10 p.m. At 70, a man who never had any sleep issues might wake up at 4 a.m., unable to fall back asleep.The Centers for Disease Control and Prevention has age-specific recommendations for how much sleep people should get each night. Understanding your sleep needs throughout different life stages — and troubleshooting the problems that arise — can clear the way for a better night’s rest.
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S22After 10 Short Years, Chick-fil-A Just Announced a Big Change  I still have to laugh when I recall the corporatespeak McDonald's used at the time, saying in internal documents that it hoped to become "a credible chicken player." ("Honey, what do you want to eat tonight? Do you want to try this new 'credible chicken player?'")Oh, and earlier this month, Panera started removing advertising and signs that read "No Antibiotics Ever," which, according to Reuters, is part of a $21 million cost-reduction plan ahead of the company's initial public offering.
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S24Linda Bean, Granddaughter of L.L. Bean Founder, Dies at 82  "Linda was known for her amazing work ethic, entrepreneurial spirit as well as her pride and dedication to her home state of Maine and L.L.Bean, the company her grandfather founded," the statement said. "Our hearts go out to her family and friends."Linda Bean served on the company's board for nearly half a century. She also bought lobster dealerships, founded the Perfect Maine Lobster brand in 2007, and owned general stores, inns and vacation rentals on Maine's central coast, where she lived in Port Clyde.
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S26Small-Business Owners Are Reducing or Eliminating Office Space  The outlook for office space is tied up in the legacy of the pandemic, with fluctuating employee habits and company preferences influencing the market in sometimes cooperative and sometimes clashing currents. Amid this changing and changeable dynamic, it's often difficult to get an accurate read on the state of play between continued remote work and the return to the office. A pair of recent studies provides a bit better view of where things stand, particularly with a view to how many business owners may be using staff preferences for working at home as a good way to cut way down on office rents.It's likely that it will take more time for companies to fully settle on what kind of work arrangements they embrace as long-term policy. For now, the results of two studies shed a little insight on how bosses can look at the approaches of their peers. One, from small business lending company Clarify Capital, offers some interesting, somewhat surprising lessons about how entrepreneurs are managing work spaces in the wake of the pandemic. Toppping that list is that "three in four business owners don't currently rent an office space."
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S278 Ways to Go From Burnout to Balance  Achieving a balance between work and well-being is necessary for sustained success and fulfillment. Yet, burnout always seems to catch up to the best of business owners and industry professionals before they even know it. "I started small," says Chris Christoff, co-founder of MonsterInsights, a WordPress plugin for Google Analytics based in West Palm Beach. "I set boundaries like no work emails after dinner and actually taking my lunch break. If you're in a similar position, start setting small but meaningful boundaries to better balance your time and your life."
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S32Is Crypto Cleaning Up Its Act? This article argues that markets in crypto-assets such as Bitcoin are maturing. This is partly due to firmer regulation and a greater willingness of crypto-asset creators to accept existing regulation. But there is also evidence that innovative moves by crypto-asset issuers to create new vehicles for investment in crypto-assets have improved price efficiency and market liquidity, making investment in crypto-assets safer for investors.
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S15What is the Islamic State Khorasan Province? - The Economist (No paywall)  TWO WEEKS before gunmen stormed the Crocus City Hall near Moscow, killing at least 137 people, American intelligence warned that “extremists” had “imminent plans” to attack large events in the city. On March 7th Russian security services said they had foiled an attack by Islamic State (IS), a jihadist outfit, on a synagogue in Moscow. So it was little surprise that, hours after the Crocus City attack, the group claimed responsibility. On March 25th four suspects, reportedly from Tajikistan, appeared in court. American officials believe they are part of the Islamic State Khorasan Province (ISKP). What is this outfit, and what threat does it pose?
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S20The "hero's journey" isn't as universal as you think  In J.R.R. Tolkien’s 1937 novel The Hobbit, Bilbo Baggins’ quiet, uneventful life is upended by the sudden arrival of the wizard Gandalf, who asks him if he’d like to go on an adventure. Unwilling to trade his comfortable surroundings for the great unknown, Bilbo declines Gandalf’s offer. It’s not until the dwarves question his usefulness that the prideful hobbit decides to tag along and help them reclaim their forlorn homeland. Although initially unsure of his own abilities, Bilbo proves to be the group’s most valuable asset, saving them from danger time and time again. After helping defeat the dragon Smaug, Bilbo returns to the Shire wiser, happier, and more confident. The end.The Hobbit is a textbook example of what comparative mythologist Joseph Campbell calls the monomyth or the “hero’s journey.” The concept, based on his lifelong study of myths and legends from across the globe, is a narrative blueprint shared by many well-known stories. Formulated in Campbell’s 1949 book The Hero with a Thousand Faces, the journey can be divided into eight steps:
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S33How Pixar Fosters a Culture of Vulnerability at Work  In an era where the boundary between work and personal life is increasingly blurred, navigating personal story sharing demands a nuanced approach. For workers, sharing the personal remains essential to their well-being and success, but requires an intentional and strategic approach. The way forward for leaders involves dismantling workplace paradigms that penalize some individuals for sharing with vulnerability. To harness the power of storytelling in the workplace, we must work toward eliminating structures that only favor some for sharing authentically. By dismantling these barriers, we pave the way for a more inclusive and empowering environment where the experiences of all individuals are valued and celebrated.
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S37The Essentials: Handling Fierce Criticism  Two women who’ve felt the heat because of decisions they’ve made or arguments they’ve put forward—or simply because of who they are—reflect on the ways they’ve steeled themselves for harsh critiques and dealt with the fallout. Patti Neuhold-Ravikumar describes the preparation and the presence of mind she summoned as a university president communicating contentious budget cuts. Ruchika Tulshyan brings her expertise in DEI and women’s leadership to contextualize those experiences, and she describes her own experiences with online harassment and how she’s dealt with skeptics.
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S38China's EV price war is killing brands and infuriating consumers  Mandy Pan thought she couldn’t go wrong with her first major purchase out of university: a silver plug-in hybrid from China’s leading electric vehicle maker, BYD. The compact sedan, called Qin Plus, was a popular choice for its affordability and low energy consumption. Pan, a 22-year-old from China’s eastern province of Zhejiang, asked her father for a down payment on a five-year loan to pay for the 94,800-yuan ($13,168) car. But less than four months later, as Chinese EV makers fight a fierce price war, the cost of BYD’s Qin Plus model has dropped by 15,000 yuan ($2,084) — more than what Pan makes in three months at her entry-level job. She was also shocked by the high insurance premiums for plug-in hybrids, and the long charging times.
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S41The 9 Best Drones (2024): Budget, Toys, Professional Video ![]() If you buy something using links in our stories, we may earn a commission. This helps support our journalism. Learn more. Please also consider subscribing to WIREDIt's no exaggeration to say that drones have changed the way we view the world. They've taken once-difficult and expensive moviemaking techniques and made them accessible to anyone. Videos that previously required a camera crew, expensive cranes, and hours of filming can now be done in minutes by the best drones with the tap of a single Auto Takeoff button.
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S46Meta Kills a Crucial Transparency Tool At the Worst Possible Time ![]() Earlier this month, Meta announced that it would be shutting down CrowdTangle, the social media monitoring and transparency tool that has allowed journalists and researchers to track the spread of mis- and disinformation. It will cease to function on August 14, 2024âjust months before the US presidential election.Meta's move is just the latest example of a tech company rolling back transparency and security measures as the world enters the biggest global election year in history. The company says it is replacing CrowdTangle with a new Content Library API, which will require researchers and nonprofits to apply for access to the company's data. But the Mozilla Foundation and 140 other civil society organizations protested last week that the new offering lacks much of CrowdTangle's functionality, asking the company to keep the original tool operating until January 2025.
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S28Mielle Organics Founder Monique Rodriguez to Launch Her Own Venture Fund  The entrepreneur, alongside her husband and Mielle co-founder Melvin Rodriguez, is planning to launch her own investment fund, which she confirmed before a live audience on Thusday last week at Female Founders Day, an event produced by the Female Founder Collective, a network for female-led businesses. Rodriguez did not provide specifics in terms of their timeline or target size of the fund, and requests for comment were unanswered at the time of publication. In conversation with Inc. Executive Editor Diana Ransom, Roriguez said that the fund's mission would drive all of her future investments in other founders."I want to be that person I didn't have in this space," said Rodriguez, referring to her trials in fund raising. "I didn't realize how hard it is to actually raise money. It's extremely hard, especially being a Black woman and not having the experience, and not having the resources, access, and mentorship."
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S21Forging a path to human-centered leadership  A human-centered approach to leadership needs to incorporate three essential behaviors: intentional collaboration; empathetic management; and an openness to flexible work experiences.While few leaders would dispute the benefits of such behaviors, the pursuit of competitive advantage can make profits versus people seem a binary choice. In truth, the two are inescapably interdependent.
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S34How Do I Get Results Without Feeling Burned Out?  He’s a leader with a passion for going the extra mile and achieving results. But he’s struggling with how long he can sustain the level of effort and time required to meet the demands of his new role. Host Muriel Wilkins helps this leader unpack what drives his work habits, redefine how he demonstrates his value, and align his workload with his overall goals.
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S36Research: How Different Fields Are Using GenAI to Redefine Roles  The interactive, conversational, analytical, and generative features of GenAI offer support for creativity, problem-solving, and processing and digestion of large bodies of information. Therefore, these features can act as cognitive resources for knowledge workers. Moreover, the capabilities of GenAI can mitigate various hindrances to effective performance that knowledge workers may encounter in their jobs, including time pressure, gaps in knowledge and skills, and negative feelings (such as boredom stemming from repetitive tasks or frustration arising from interactions with dissatisfied customers). Empirical research and field observations have already begun to reveal the value of GenAI capabilities and their potential for job crafting.
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S39The Next Big Battle Over Abortion Has Begun ![]() On Tuesday, the Supreme Court of the United States will hear oral arguments in a challenge to abortion pill access across the country, including in states where abortion is legal. The stakes for abortion rights are sky-high, and the case is the most consequential battle over reproductive health care access since Roe v. Wade was overturned in 2022.At the center of this fight is mifepristone, a pill that blocks a hormone needed for pregnancy. The drug has been approved by the US Food and Drug Administration for more than two decades, and it's used to treat some patients with Cushing's syndrome, as well as endometriosis and uterine fibroids. But its primary use is the one contested nowâmifepristone is the first of two pills taken in the first 10 weeks of pregnancy for a standard medication abortion, along with the drug misoprostol.
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S40A Deepfake Nude Generator Reveals a Chilling Look at Its Victims ![]() As AI-powered image generators have become more accessible, so have websites that digitally remove the clothes of people in photos. One of these sites has an unsettling feature that provides a glimpse of how these apps are used: two feeds of what appear to be photos uploaded by users who want to "nudify" the subjects.The feeds of images are a shocking display of intended victims. WIRED saw some images of girls who were clearly children. Other photos showed adults and had captions indicating that they were female friends or female strangers. The site's homepage does not display any fake nude images that may have been produced to visitors who aren't logged in.
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S48Here Comes the Flood of Plug-In Hybrids ![]() Last week, the Biden administration made it official: American cars are really going electric.The US Environmental Protection Agency finalized a rule, long in the works, that will require automakers selling in the United States to dramatically boost the number of battery-powered vehicles sold this decade, putting a serious dent in the country's carbon emissions in the process. By 2032, more than half of new cars sold must be electric.
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