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 S20FDA Approves New Cellular Therapy For Aggressive Skin Cancer - Forbes (No paywall)   "This is a major advance for patients with metastatic melanoma," said Daniel Olson, M.D., medical oncologist at the University of Chicago Cancer Center, one of the locations offering the therapy. "Currently, our available therapies can offer control or cure for just over 50% of patients with advanced melanoma, leaving many patients without adequate treatment options."The cell-based treatment is known as a tumor infiltrating lymphocyte therapy and its production is a complex several-step process started by extracting immune cells from a patient's tumor during surgery. The cells are then genetically analyzed to identify those that are are naturally primed to attack the tumor, expanding these cells in the lab to boost their numbers before injecting them back into the patient to tackle the cancer.
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S47Yelp: It's gotten worse since Google made changes to comply with EU rules  To comply with looming rules that ban tech giants from favoring their own services, Google has been testing new look search results for flights, trains, hotels, restaurants, and products in Europe. The EU’s Digital Markets Act is supposed to help smaller companies get more traffic from Google, but reviews service Yelp says that when it tested Google’s design tweaks with consumers it had the opposite effect—making people less likely to click through to Yelp or another Google competitor.
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S19Panda Will Return To San Diego Zoo As China Plans To Resume Popular Diplomatic Gesture - Forbes (No paywall)  The number of pandas living in U.S. zoos has dwindled over the past few years amid growing tensions between Beijing and Washington. Both Memphis Zoo and the National Zoo in Washington D.C. returned their pandas to China last year after their loan agreement to host the animals expired. Just four pandas now remain in the United States, all in Zoo Atlanta, whose loan agreement is set to expire later this year.The first pandas were sent to the U.S. from China in 1972 after a thawing of the relationship between the two countries following President Richard Nixon’s visit. This “panda diplomacy” grew over the next few decades with Beijing lending out more pandas to zoos across the world, usually on 10-year contracts. Tensions between the U.S. and China and the recent departure of many pandas from American zoos led to speculation that China may be reeling back its panda diplomacy efforts with the U.S. But during his visit to San Francisco last year, Xi hinted that the San Diego Zoo may once again get to host the endangered bear. He said: “I also learned that the San Diego Zoo and the Californians very much look forward to welcoming pandas back” and said his government intends to do its best to “meet the wishes of the Californians so as to deepen the friendly ties between our two peoples.”
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S5Why Do Cats Hate Water? The Aversion Has A Simple Answer  Given the choice, most cats would do just about anything to avoid getting wet. While this phobia might seem a bit extra, it turns out our feline companions have a good reason to avoid water — and it all comes down to science.“Cats as a species tend to avoid water,” says Malini Suchak, an anthrozoology professor at Canisius University in New York. This aversion, she says, isn’t due to a preservation instinct; cats can both swim and float if necessary. Rather, experts suspect that this hydrophobia comes from water’s effects on their fur coats, though Suchak isn’t aware of any formal investigations of the behavior.
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S28I Just Tried Chik-Fil-A for the First Time. I Was Quietly Surprised, But Not by the Food  While on a business trip in Orlando, I had just concluded a day filled with client meetings and intense workshops. As the adrenaline waned, my hunger set in. Craving a change of scenery and some fresh air, I ventured out for a drive, in search of a place to eat.That's when I spotted Chik-Fil-A, its sign a beacon of neonic red. As a Canadian, my familiarity with Chik-Fil-A was limited, given its recent introduction in our region. Curiosity piqued, I decided to give their famous original chicken sandwich a try, keen to understand the fervor surrounding the brand.
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S39Frequent Heavy Rain Has Made California a Mudslide Hotspot ![]() This story originally appeared on Inside Climate News and is part of the Climate Desk collaboration.Picture the minute hand at about 8 past the hour. That's the slope of Viet's backyard in southern Los Angeles County. It's a bit too aggressive for a slip-and-slide. In fact, Viet doesn't even let his 7-year-old daughter play on the family's small back patio.
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S40A Mysterious Leak Exposed Chinese Hacking Secrets ![]() Today marks two years since Russia launched its full-scale invasion of Ukraine. This week, we detailed the growing crisis in Eastern Ukraine, which is now littered with deadly mines. As it fights back the invading Russian forces, Ukraine's government is working to develop new mine-clearing technology that could help save lives around the globe.A leaked document obtained by WIRED has revealed the secret placement of gunshot-detection sensors in locations around the United States and its territories. According to the document, which ShotSpotter's parent company authenticated, the sensors, which are used by police departments in dozens of metropolitan areas in the United States, are largely located in low-income and minority communities, according to WIRED's analysis, adding crucial context in a long-running debate over police use of the technology.
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S48The Strongest Case Against Donald Trump  If Donald Trump beats Nikki Haley on Saturday in her home state of South Carolina, where he leads in the polls, he's a cinch to win the GOP nomination. And if he wins the GOP nomination, he has a very good shot at winning the presidency. So it's worth entertaining the strongest argument against Trump, which many Americans haven't heard before: that Trump brings out the worst in many of usâhis critics and supporters alike.To really make this anti-Trump argument, one must go so far as to acknowledge that the anti-Trump coalition has sometimes engaged in unreason, hysteria, and abuses of power. The name for this phenomenon is Trump Derangement Syndrome.
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S427 Best Theragun-Alternative Massage Guns (2024): Portable, Affordable, and Heat Therapy ![]() If you buy something using links in our stories, we may earn a commission. This helps support our journalism. Learn more. Please also consider subscribing to WIREDMassage guns, also known as percussive therapy devices, help relax and soothe sore muscles and decrease recovery time, whether you're an athlete or just hunching over a desk all day. Some even include heat and cold therapy. We've tested several across price ranges, and here you'll find our favorites, plus some fun extras like a massaging pillow and goggles.
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S49Could South Carolina Change Everything?  For more than four decades, South Carolina has been the decisive contest in the Republican presidential primariesâthe state most likely to anoint the GOP's eventual nominee. On Saturday, South Carolina seems poised to play that role again.Since the state moved to its prominent early position on the GOP presidential-primary calendar in 1980, the candidate who has won there has captured the nomination in every contested race except one. Given Donald Trump's overall lead in the GOP race, a victory for him in South Carolina over Nikki Haley, the state's former governor, would likely uphold that streak.
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S33Warren Buffett Listed 7 Specific  And as I read the letter fully, I found a theme that me smile -- one that I really only saw on the second reading. It's almost as if there was a wry joke that ran its length, and that seems to me like "the most Buffett thing ever" in retrospect.Perhaps the theme will come through for having listed some of the narrative points here: It's that at age 93, and still the driving force behind Berkshire, Buffett is in an almost unique position to preach about measuring things over the longe term--a theme he returns to year after year.
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S34Xiaomi Redmi Note 13 Pro+ Review: Attractive and Affordable ![]() If you buy something using links in our stories, we may earn a commission. This helps support our journalism. Learn more. Please also consider subscribing to WIREDMidrange phones are constantly tightening the gap with top-tier phones. There are still plenty of pricey flagship phones, but with ever diminishing returns. How useful are the unique features you find in today's flagships? It's debatable. Xiaomi's Redmi Note 13 Pro+ is a prime example of a midranger that can go toe-to-toe with far more expensive devices.
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S18Steve Jobs adopted a no 'bozos' policy and said the best managers are those who never wanted the job--here are his 3 best management tips - Fortune (No paywall)  Jobs’ comment gets at the crux of a central debate in management: whether managers should actually want to be managers or not. Jobs argued the people who were least expecting to be leaders ended up being the best managers in the long run. That’s because other employees were more likely to actually learn something from them because they’ve mastered that skill—rather than only focusing on management techniques.“There’s no way in the world anybody else would give me this chance to run this kind of operation,” Coleman said in a 1980s interview. “I don’t kid myself about that there’s an incredible high risk—both for myself personally and professionally, and for Apple as a company—and put a person like myself in this job.”
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S45How First Contact With Whale Civilization Could Unfold - The Atlantic (No paywall)  One night last winter, over drinks in downtown Los Angeles, the biologist David Gruber told me that human beings might someday talk to sperm whales. In 2020, Gruber founded Project CETI with some of the world’s leading artificial-intelligence researchers, and they have so far raised $33 million for a high-tech effort to learn the whales’ language. Gruber said that they hope to record billions of the animals’ clicking sounds with floating hydrophones, and then to decipher the sounds’ meaning using neural networks. I was immediately intrigued. For years, I had been toiling away on a book about the search for cosmic civilizations with whom we might communicate. This one was right here on Earth.Sperm whales are the planet’s largest-brained animals, and their nested social structures are immense. About 10 whales swim together full-time as a unit. They will sometimes meet up with others in groups of hundreds. All of the whales in these larger groups belong to clans that can contain as many as 10,000 animals, or perhaps more. (The upper limit is uncertain, because industrial whaling reduced the animals’ numbers.) Sperm whales meet just a fraction of their fellow clan members during their lifetime, but with those they do meet, they use a clan-specific dialect of click sequences called codas.
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S10Amazon is About to Destroy One of the Best Ways to Watch Television  Where do TV shows go when they meet their end? When one-season wonders are canceled, they usually live out the rest of their lives in the bowels of streaming archives, but now they’re starting to just be deleted altogether. If fans are lucky, these shows will be available to purchase digitally, but sometimes they’re erased forever to save streaming platforms a few bucks.There was always one last hope for archiving television and making it available to fans, but even that may now be in trouble. The apparent end of the most unsung streaming service may be signaling the end of an entire era of TV streaming.
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S11Elon Musk's Neuralink Has a Serious Ethical Problem, a Neurosurgeon Warns  Putting a computer inside someone’s brain used to feel like the edge of science fiction. Today, it’s a reality. Academic and commercial groups are testing “brain-computer interface” devices to enable people with disabilities to function more independently. Yet Elon Musk’s company, Neuralink, has put this technology front and center in debates about safety, ethics, and neuroscience.In January 2024, Musk announced that Neuralink implanted its first chip in a human subject’s brain. The Conversation reached out to two scholars at the University of Washington School of Medicine – Nancy Jecker, a bioethicist, and Andrew Ko, a neurosurgeon who implants brain chip devices – for their thoughts on the ethics of this new horizon in neuroscience.
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S12Hulu Just Quietly Added the Smartest Time-Bending Movie of 2023  When you lose someone close to you, you’re left haunted not only by their sudden absence but also by what will never be. Few things nag at a person more than the things they wish they’d said, and when mortality gets involved, those unspoken conversations tend to ring even louder in your ears.It’s hard not to let the weight of what you’ve lost hold you in place, and few films understand that better than All of Us Strangers. The Andrew Haigh-directed drama offers a decidedly non-traditional twist on a ghost story, one that prioritizes moments of profound emotional catharsis and personal reckonings. It was one of the best films to hit theaters in 2023, and now that it’s streaming on Hulu it deserves your attention.
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S17S26S295 Ways Businesses Can Seize Marketing Opportunity in an Election Year  This is the time when CEOs should remember the famous Sun Tzu phrase "Victory comes from finding opportunities in problems." The arrival of an election year is not just a political event. It's an opportunity for businesses to navigate change strategically and emerge stronger. However, elections can have a profound impact on your operations. In which way should your business use the election year to its advantage and turn political uncertainty into opportunity? As a principle, I advise my consulting clients that there's an opportunity in every situation and there's always room for improvement. First, you should proactively analyze how political outcomes can shape policies, by anticipating potential impacts on your industry. Staying attuned to political trends and public sentiment is crucial. Once the research is done, I recommend you and your team align possible strategies with expected changes to thrive in evolving regulatory environments.Â
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S41It's Apparently Easy to Crack the Apple Vision Pro's Front Screen ![]() AppleâÂÂs mixed-reality headset is selling well, but itâÂÂs embroiled in a new mystery thatâÂÂs proving tough to crack.As first reported by MacRumors, some customers have discovered a mysterious crack appearing vertically down the center of the front-facing screen on their Vision Pro headsets. The reports have come from only a small number of users, most of them talking about it on Reddit, which can be an unreliable source. That said, Engadget reports that the same crack has occurred on its review unit. The folks affected say they havenâÂÂt mishandled the devicesâÂÂthereâÂÂs been no dropping or smashing that could create the crack in the laminated glass screen. So itâÂÂs not yet clear what exactly is causing the problem, or whether it actually affects the performance of the Vision Pro.
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S15NRA loses New York corruption trial over squandered funds - retired longtime leader Wayne LaPierre must repay millions of dollars  A New York jury found on Feb. 23, 2024, that the National Rifle Association and three of its current and former officials had broken the state’s laws by misusing charitable assets. It also determined that two of the officials should repay the gun group millions of dollars.The verdict followed a six-week corruption trial that came nearly four years after New York Attorney General Letitia James sued the NRA and almost five years after investigative journalists reported that the group’s leaders, vendors and contractors had improperly spent the nonprofit’s funds on lavish travel and other personal expenses. The NRA responded to the verdict by saying it had been “victimized by certain former vendors and ‘insiders’ who abused the trust placed in them by the Association” and listing steps it had already taken to get its house in order.
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S35This Solar Eclipse Simulator Helps You Find the Best Place to Watch From ![]() A total solar eclipse is coming to North America on April 8. The Great North American Eclipse, as it has been dubbed, will be visible across 13 US States, plus parts of Mexico and eastern Canada. But it will not look the same for everybody.For those living along the path of totalityâthe projection of the moon's shadow on the Earth's surfaceâthe celestial event is bound to delight. For everyone else, experiencing the total eclipse will require extensive planning ⦠which, if you're organized, should've already happened, but let's face it, it probably has not.
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S50How America Became Addicted to Therapy  A few months ago, as I was absent-mindedly mending a pillow, I thought, I should quit therapy. Then I quickly suppressed the heresy. Among many people I know, therapy is like regular exercise or taking vitamin D: something a sensible person does routinely to clear out the system. BetterHelp ran an ad where a woman says she's ignoring a guy's texts because he doesn't see a therapist. "Hard pass," she explains. "Red flag." Therapy for many people has no natural endpoint. It's just "baked into my life," as one patient told the psychiatrist Richard Friedman, explaining why he'd been seeing a therapist for the past 15 years.Therapy is so destigmatized now that a lot of us sound like therapists. We're "codependent," "triggered," "catastrophizing." We cut off our friends who are toxic. Justin Bieber doesn't fear an exposé on the damage of childhood fame; he freely discusses his trauma and healing. Oprah wonders what happened to you. And once you figure it out, you'll find hours of free advice on TherapyTok.
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S3The Best Sci-Fi Shooter of the Year Can't Escape Gaming's Worst Trend  At the farther end of your ship, you can see a glimpse of the ongoing conflict as you land on an alien planet. Outside your window are fellow combatants, represented as ships in orbit. Whenever a group fails a mission, their ship is shot down in real-time. It's a grim yet effective reminder of the thousands of people out there cooperating toward the same goal.Last weekend, Helldivers 2 saw over 400,000 concurrent players on Steam alone (plus however many gamers on PlayStation 5). It's an unprecedented success for developer Arrowhead and publisher Sony. The servers can't keep up with such an influx, and the team has been working "many late nights" since the online extraction shooter launched on Feb. 8. It is, deservedly, the game of the moment. But for how long?
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S4Are Supplements FDA Approved? Inside the Wild West of Diet Pills and Protein Powder  Dietary supplements are a big business. The industry made almost $39 billion in revenue in 2022, and with very little regulation and oversight, it stands to keep growing.The marketing of dietary supplements has been quite effective, with 77 percent of Americans reporting feeling that the supplement industry is trustworthy. The idea of taking your health into your own hands is appealing, and supplements are popular with athletes, parents, and people trying to recover more quickly from a cold or flu, just to name a few.
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S46A Guide for New Middle Managers  Congratulations! You’ve just been promoted to your first leadership position. You’re no longer at the same level as your former peers but you’re not a senior leader or an executive either. You’re in the middle, which means you have to figure out how to satisfy the needs of those above and below you.
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S43A Vending Machine Error Revealed Secret Face Recognition Tech ![]() Canada-based University of Waterloo is racing to remove M&M-branded smart vending machines from campus after outraged students discovered the machines were covertly collecting face recognition data without their consent.The scandal started when a student using the alias SquidKid47 posted an image on Reddit showing a campus vending machine error message, "Invenda.Vending.FacialRecognitionApp.exe," displayed after the machine failed to launch a face recognition application that nobody expected to be part of the process of using a vending machine.
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S135 Years Ago, A Notorious Gaming Flop Predicted The Future of the Industry  The goal of a live service game is to give players an experience they can enjoy forever, or as close as possible to it. Their persistent worlds, constantly updated with exciting things to see, can nurture communities that endure for years. With years of new additions, these games have time to evolve, offering totally different experiences to players from one era to the next.From its first announcement, Anthem was an oddity. Developer BioWare is known for single-player RPGs with deep stories, vibrant worlds, and casts of loveable characters that have inspired more fan art than a person could see in a single lifetime. Anthem, which was released on February 22, 2019, has none of that.
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S388 Best Deals: Streaming Devices, Smart TVs, and Projectors ![]() I have big plans this weekend: watching the entirety of the new Avatar: The Last Airbender live-action series on Netflix. Maybe you've got the same thing on your watchlist, or maybe you're just looking to upgrade your TV and streaming setup. Either way, we've rounded up some great deals on streaming devices, soundbars, a smart TV, and projectors to watch anything you like easier and better than ever.Special offer for Gear readers: Get WIRED for just $5 ($25 off). This includes unlimited access to WIRED.com, full Gear coverage, and subscriber-only newsletters. Subscriptions help fund the work we do every day.
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S6Insects Are Obsessed With Light For An Extremely Uncanny Reason  It’s an observation as old as humans gathering around campfires: Light at night can draw an erratically circling crowd of insects. In art, music, and literature, this spectacle is an enduring metaphor for dangerous but irresistible attractions. And watching their frenetic movements really gives the sense that something is wrong – that instead of finding food and evading predators, these nocturnal pilots are trapped by a light.Sadly, centuries of witnessing what happens have produced little certainty about why it happens. How does a simple light change fast, precise navigators into helpless, flittering captives? We are researchers examining flight, vision, and evolution, and we have used high-speed tracking techniques in newly published research to provide an answer.
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S14S31The Solution For Useless Meetings: 'Cast'  Meeting waste is a comparable crisis when you consider the Sasquatch-size carbon footprint that is generated by those who fly and drive to endless sessions whose only outcome, typically, is agreement on scheduling a follow-up.The practice of running more effective meetings has become an industry all by itself. Suggestions range from the gratingly obvious--the Harvard Business Review, without any shame, advises that you ask "What is this meeting intended to achieve?"--to the gimmicky: When you stand during a meeting, the duration is shortened by 25 percent.
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S32From Frustrated to Fan: How Best Buy's Service Won Me Over  As an entrepreneur and management professor, I've observed a concerning trend: The apparent demise of customer service in retail, often marred by disinterested, phone-preoccupied cashiers. Leaders can glean important lessons from large companies on how not to treat customers. A recent experience at Best Buy in New Jersey has restored my faith in retail-based customer service and provided valuable insights for all business owners.The incident began with an online laptop purchase, which, unfortunately, arrived damaged because of shipping issues. Expecting a complicated resolution process, I contacted customer service and was advised to visit the store. Despite my apprehensions about the time it would take, my experience was remarkable.
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S36Why Joe Biden Finally Joined TikTok ![]() Joe Biden's presidential campaign landed on TikTok with a thud, drawing ire from critics across the political spectrum. Left-leaning users have called the campaign's posts tone-deaf in light of the ongoing atrocities in Gaza. Pointing to the app's connections to China, Republicans demanded the president delete the account altogether. But the campaign has shrugged off its criticsâwhile learning to navigate the popular and sometimes hostile platform.As recently as last summer, the Biden team said it had no plans to join TikTok. Before the account's launch on Super Bowl Sunday, the campaign's TikTok strategy was to steer clear. For years, it was more politically convenient to work with young, pro-Biden influencers to push the president's message on the controversial platform than to engage with it directly. But after weeks of careful planning, the campaign decided that it couldn't hold out any longer.
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S21S275 Proven Ways to Get Better Sleep and Wake Up Refreshed  Dreaming of a good night's sleep? Aren't we all. But for many, getting seven or eight hours of sleep a night (or even five or six) seems like a dream that is always just out of reach. And it's no wonder. With overpacked schedules and stress and anxiety through the roof, getting a good night's sleep is a very real challenge.According to the Sleep Foundation, adults need seven or more hours of sleep a night. However, the reality is that more than 33 percent of Americans fail to hit this not-all-that-high mark. Not only that, but about half of workers say they're tired during their typical day on the job.
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S44Isolated for six months, scientists in Antarctica began to develop their own accent  It was a suitably icy farewell salute: a handful of snowballs arcing through the sky towards RSS Ernest Shackleton as the ship slipped away from the wharf. The vessel was setting out across the stormy Southern Ocean, leaving 26 hardy souls behind on a snowbound island at the frozen tip of the Antarctic Peninsula. Those waving goodbye from the shore were watching their last tangible link to the rest of the world glide off through the bitterly cold water. Ahead of them lay six months of winter, effectively marooned, in the coldest continent on the planet."They say it is quicker to get to someone on the International Space Station than it is to medically evacuate someone from Antarctica in the winter," says Marlon Clark, one of those 26 international researchers and support staff left behind at the British Antarctic Survey's Rothera Research Station on Adelaide Island, just to the west of the Antarctic Peninsula in March 2018. Antarctica is the least-inhabited continent on the planet – it has no permanent human population – with just a handful of research stations and bases scattered across the 5.4 million sq mile (14 million sq km) frozen landscape. "So, you're isolated," says Clark. "There's a lot of mystery and lore about 'a winter in Antarctica'. Anticipation was the strongest feeling as well as realising, 'OK, this is real, I’m going to be here for a long, long time'."
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S16Nigeria's ban on alcohol sold in small sachets will help tackle underage drinking  Alcohol consumption is growing among young Nigerians. Although alcohol consumption is not new to Nigerian society, historically only adults consumed it because drinking signified that one was an elder. Unwritten rules constrained youths from drinking palm wine, which was the only available alcoholic beverage then. It was believed they were too immature to handle the intoxicating effects of alcohol. Nowadays, a rising number of Nigerian adolescents and young adults consume alcohol. Some even see drinking as fashionable and those who abstain as old fashioned. Studies have shown that young Nigerians are consuming more alcohol. For example, studies published in 2015, 2021 and 2023 found a 30%, 34% and 55.8% drinking prevalence among youths in Nigeria.
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S22NASA tests autonomous space robots for off-world construction  NASA is testing out autonomous space robots to build shelters and solar arrays on the moon and Mars.The challenge: With Artemis, NASA isn’t just trying to return astronauts to the moon — it hopes to lay the foundation for establishing a long-term presence on the lunar surface so that it can develop the tech needed to get people to Mars and beyond.
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