Antiretroviral treatment using monthly cabotegravir and rilpivirine injections is more effective than daily pills for people who have had difficulty achieving good adherence and maintaining viral suppression, according to an announcement this week from ViiV Healthcare.

An injectable version of PrEP, which offers protection against the virus for up to two months, is rolled-out in Zambia.

Behind many pandemic-era debates are deep divisions between two schools of thought in the world of health care.

There’s a comeback of sexually transmitted infections (STIs) in South Africa and around the world. The Gauteng Department of Health recently reported an increase of newly acquired STIs, in particular gonorrhoea and chlamydia. This spike in cases call for management guidelines and awareness programmes to be reviewed.

A tribute to Paul Farmer, a global health pioneer and founders of Partners in Health who passed away in 2022, this article reflects on his idea of "accompaniment"—an emphasis on empathy, equity and social justice for the economically disadvantaged and marginalized.

Born with HIV in 1984, she began raising awareness on television when she was 6 years old.

Current data supports the use of doxy-PEP in cisgender MSM and transgender women to prevent bacterial STIs but critical issues about safety and antimicrobial resistance still need to be answered.

A reasonable approach in the interim is to confine doxy-PEP to those with a bacterial STI in the last 12 months while gathering more data. Additional studies in women, low-income countries and in the Black and Hispanic population are needed.

There's been an alarming surge nationwide in syphilis cases. As cases increase, providers are having to ration penicillin shots, which are in short supply.

People living with HIV in South Africa expressed a lack of awareness, confusion, and scepticism regarding U=U, according to a recent qualitative study published in PLoS ONE.

Healthcare providers acted as gatekeepers and expressed fears that U=U knowledge would lead to increases in condomless sex.

Weinstein repeated discredited theories to Rogan about HIV not being the cause of AIDS, alarming and infuriating public health experts.

Many women with HIV reported using contraceptives in a survey, but just over half remembered having a conversation with a provider about them, results showed.

Several factors, including discrimination, homelessness, and violence, help explain why transgender women have a higher risk for HIV, according to a report from the federal Centers for Disease Control and Prevention.

Funding through the US President’s Emergency Plan for AIDS Relief (PEPFAR) not only helps to improve health, but also positively impacts a wide range of other national indicators, including economic growth and retention in school, a modeling study found.

Young women in sub-Saharan Africa are a priority population for HIV prevention, yet challenges with adherence and persistence to HIV pre-exposure prophylaxis (PrEP) are common. This study involved the development and pilot testing of My Way-a novel delivery system for PrEP and co-packaged sexual health services.

Despite PrEP implementation in South Africa, awareness of PrEP among men with HIV in rural areas remains low. Engaging men living with HIV to support their partners in accessing PrEP could be an innovative strategy to promote HIV prevention. Additionally, providing men with comprehensive reproductive health information can empower them to make more informed decisions, adopt safer sexual practices, and challenge societal norms and stigmas around HIV.

Daily oral PrEP with FTC-TDF in high-risk Thai adolescents is feasible, accepted, well-tolerated, and had no increased risk compensation; however, low adherence was a major challenge. Adolescent-specific PrEP strategies including long-acting modalities are needed for successful HIV prevention.

Themes directly speak to recommendations to adjust education and policy strategies for HIV and COVID-19 prevention and intervention. Such recommendations, (1) amplifying Black voices, (2) investing sustainable dollars into Black communities, and (3) leaning into advocacy, can bolster the foundation for the HIV workforce and Black community to break ineffective response patterns and lead the fight against these systemic issues of inequity.

Researchers at the University of Waterloo have developed a novel nanomedicine loaded with genetic material called small interfering RNAs (siRNA) to fight HIV using gene therapy.

This review addresses the evidence on doxycycline post-exposure prophylaxis (doxy-PEP) for prevention of bacterial STIs, including efficacy, safety, antimicrobial resistance (AMR), acceptability, modeling population impact and evolving guidelines for use.

Observing the rapid opening and closing of a glycoprotein on the HIV virus's envelope, within just microseconds, is offering researchers fresh insights into the virus's surface. Broadly neutralizing antibodies may be able to attach to this small structure, inhibiting its ability to open, an avenue for vaccine research.

Researchers are developing monoclonal antibodies (mAbs) to prevent HIV, which can be used alongside existing oral pre-exposure prophylaxis (PrEP) in clinical trials. In a study of 48 US participants who received the HIV-1 mAb VRC01 and stayed HIV-free, a further analysis showed that in PrEP users, VRC01 was cleared from the body 0.08 L/day faster and had a 14% lower efficacy in preventing HIV-1 compared to non-PrEP users.