From Health Affairs Today <[email protected]>
Subject Orphan Drug Label Expansions
Date January 31, 2024 9:05 PM
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Wednesday, January 31, 2024 | The Latest Research, Commentary, and News from Health Affairs

Dear John,

Last week, we published an ahead-of-print article from Devlin Hanson and Sarah Gillespie of the Urban Institute that examines the impacts of the Housing First initiative on health care use, Medicaid enrollment, and mortality among people experiencing chronic homelessness who had frequent arrests and jail stays.

Be sure to check out this article in anticipation of our theme issue on housing and health that will be released next week!

Read the Article
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Analyzing Orphan Drug Approvals (1990–2022)

The Orphan Drug Act of 1983 created financial incentives for the development of rare disease drugs.

Recently, concerns have been raised about whether the Orphan Drug Act’s incentives are needed to promote drugs that treat both rare and common diseases.

In the January issue of Health Affairs, Kathleen Miller of the Department of Health and Human Services and Michael Lanthier of the Food and Drug Administration (FDA) examine 491 novel orphan drugs approved by the FDA between 1990 and 2022 ([link removed] ) .

Miller and Lanthier find that of these 491 drugs, 65 percent have been approved for a single rare disease, 15 percent have been approved for multiple rare diseases, and 20 percent have been approved for both rare and common diseases.

Among other findings, the authors determine that 10 percent of orphan drugs had a subsequent indication approval for a pediatric population.

Check out additional research articles featuring Miller and Lanthier below:

- Trends In Orphan New Molecular Entities, 1983–2014: Half Were First In Class, And Rare Cancers Were The Most Frequent Target ([link removed] )
- An Improved Approach To Measuring Drug Innovation Finds Steady Rates Of First-In-Class Pharmaceuticals, 1987–2011 ([link removed] )

Read the Article
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health-affairs-event-housing-health-02-2024_enewsletter ([link removed] )

Millions in the United States experience housing instability (the continuum between homelessness and stable, secure housing), which can threaten their health and well-being.

The February 2024 issue of Health Affairs explores health across a range of housing policy areas, centered around health equity; highlights best practices and lessons learned by communities across the country; and identifies potential policy interventions.

You are invited to join us on Tuesday, February 6, 2024, at 1:00 p.m. (Eastern) for a virtual forum at which authors will present their work, engage in discussion, and answer questions on these important issues. Panels include:

- Communities And Neighborhoods
- Health Sector Interventions
- Homelessness
- Housing Costs, Quality, and Stability

Register and learn more about the participating speakers below!

Find Out More
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The Fair Access In Residency (FAIR) Act Takes Aim But Misses The Mark ([link removed] )

Philip A. Gruppuso and Eli Y. Adashi

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health-affairs-journal-new-word-count-2024_eNewsletter-banner ([link removed] )

Health Affairs is implementing a new word limit for journal research articles.

Beginning with submissions received on or after April 1, 2024, the word limit will change from 5,000 words, including endnotes, to 3,250, excluding endnotes.

This change will allow for a tighter focus on core empirical research elements and create shorter, more accessible content for our audience.

Research papers using both qualitative and quantitative methods will be allowed a word count of 4,000 (excluding endnotes).

For more on this change, check out a newly released article from Editor-in-Chief Alan Weil.

Learn More
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Jobs at Health Affairs

Health Affairs is the perfect place to advance your career while contributing to the leading research and analysis on improving health policy and health care.

Our team contains a deep bench of experienced professionals in health policy, dedicated to making health care better.

Below are the current job openings at Health Affairs:

- Senior Editor ([link removed] )
- Senior Development Director ([link removed] )

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About Health Affairs

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