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Issue 1,722: November 8, 2023
Top Stories
* Immunize.org is launching a redesigned website with new features to better serve you (#IZX1)
* Immunize.org posts new standing orders templates for use of RSV vaccine during pregnancy and RSV preventive antibody for infants (#IZX2)
* Immunize.org incorporates COVID-19 and RSV vaccine considerations in its popular child and adult screening checklists for contraindications to vaccines (#IZX3)
* “Addressing Vaccination Anxiety for Infants: Strategies for Vaccine Recipients and Caregivers”: watch the 3-minute video, part of the Improving the Vaccination Experience Video Series on YouTube (#IZX4)
* FDA advises healthcare providers about administering correct dosage of Moderna COVID-19 Vaccine (2023–2024 Formula) to children age 6 months through 11 years (#IZX5)
* Institute for Safe Medication Practices warns of potential for vaccine errors related to packaging; remind staff of safety steps (#IZX6)
* “Vaccination Coverage by Age 24 Months among Children Born in 2019 and 2020—National Immunization Survey-Child, United States, 2020–2022” published in MMWR (#IZX7)
* Immunize.org updates "Vaccinations Needed during Pregnancy" patient handout to include RSV prevention (#IZX8)
* Review your COVID-19 resources with the latest version of Immunize.org’s “Checklist of Current Versions of U.S. COVID-19 Vaccination Guidance and Clinic Support Tools” (#IZX9)
* Veterans Day is November 11. Encourage more veterans to protect themselves with new Health.mil’s seasonal respiratory illness vaccine communication toolkit. (#IZX10)
* Influenza activity is low nationally but continues to increase in most parts of the country; encourage vaccination now (#IZX11)
* Journalists interview Immunize.org experts (#IZX12)
* Vaccines in the news (#IZX13)
Featured Resources
* CDC updates its website on how to implement ACIP’s shared clinical decision-making recommendations, including links to job aids for vaccinators (#IZX14)
* CDC adds customizable frames for “Wild to Mild” social media campaign to promote influenza vaccination (#IZX15)
* Hepatitis B Foundation releases guide for implementation of adult universal hepatitis B vaccination and screening (#IZX16)
* NFID posts podcast episode featuring Peter Marks, PhD, MD, of the FDA (#IZX17)
Notable Publications
* “A Prospective Cohort Study of Preconception COVID-19 Vaccination and Miscarriage” published in Human Reproduction (#IZX18)
Upcoming Events
* Virtual: Children (#IZX19) s Hospital of Philadelphia hosts Current Issues in Vaccines webinar titled “Making the Broadest, Longest-Lasting COVID-19 Vaccine” on December 6 at 12:00 p.m. (ET); CE credit offered (#IZX19)
* Virtual: Clinical Care Options hosts webinar “Ready, Set, Vaccinate! Clinical Implementation of RSV Vaccination for Older Adults” on December 6 at 12:30 p.m. (ET); CE credit offered (#IZX20)
Editorial Information (#Editorial)
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Top Stories
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Immunize.org is launching a redesigned website with new features to better serve you
Immunize.org announces the launch of our redesigned Immunize.org flagship website in the next 24 hours. Our new site will feature enhanced navigation while continuing to provide the timely, accurate resources developed and refined during our 32 years of experience providing educational support to public health professionals and the nurses, physicians, pharmacists, and medical assistants who administer vaccines.
You will continue to find:
* Curated links to the latest clinical resources
* Vaccination guidance from CDC, FDA, and major professional organizations
* VIS translations in numerous languages
* More than 1,200 Ask the Experts answers to practical clinical questions about vaccines
* Access to your bookmarked materials—all of our links remain the same
Our redesign streamlines navigation and enhances searchability on mobile devices and desktops. We’ve made it much easier for you to find exactly what you need.
New features of the redesigned Immunize.org website:
* A homepage navigation guide to introduce you to new search options
* New mobile responsive design: comfortable viewing and navigation from your phone
* Enhanced search tools: use built-in filters or enter keywords and phrases to narrow your search
* Filters and keyword searches within our Ask the Experts question database
* Featured resources showcased at a glance on our home page
* A streamlined subscription process for IZ Express
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Immunize.org's updated site goes live by November 9, and is designed to continue to support our longtime users while simplifying access to our resources by new visitors and the next generation of frontline vaccinators.
We hope our new site will make it easier for you to vaccinate with confidence. Explore it soon! We look forward to hearing what you think.
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Immunize.org posts new standing orders templates for use of RSV vaccine during pregnancy and RSV preventive antibody for infants
In recent weeks, ACIP has made routine recommendations for the prevention of RSV in infancy through either maternal RSV vaccination or infant immunization with nirsevimab preventive antibody. Immunize.org now offers two new standing orders templates: one for RSV vaccination during pregnancy, and one for nirsevimab for infants. The nirsevimab standing order template reflects the revised guidelines for eligibility for the 2023–24 season issued by CDC on October 23 in its Health Alert Network advisory concerning the shortage of nirsevimab in its initial season. The templates are:
* Standing Orders for Administering Pfizer Respiratory Syncytial Virus (RSV) Vaccine (Abrysvo) during Pregnancy ([link removed])
* Standing Orders for Administering Nirsevimab RSV Preventive Antibody to Infants (2023–24 Season Only) ([link removed])
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Related Links
* Immunize.org: Handouts: Standing Orders Templates for Administering Vaccines ([link removed]) main page
* Immunize.org: Handouts for Patients and Staff ([link removed]) main page, where you can sort materials by topic, vaccine, or language
* Immunize.org: Educational Materials for Patients and Staff ([link removed]) —an alphabetical listing of more than 230 ready-to-print staff educational materials and patient handouts
* CDC Health Alert Network Advisory: Limited Availability of Nirsevimab in the United States—Interim CDC Recommendations to Protect Infants from Respiratory Syncytial Virus (RSV) during the 2023–2024 Respiratory Virus Season ([link removed]) (10/23/23)
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Immunize.org incorporates COVID-19 and RSV vaccine considerations in its popular child and adult screening checklists for contraindications to vaccines
Immunize.org’s popular screening checklists for contraindications to vaccines for both children and adults have been updated to incorporate COVID-19-specific contraindications and precautions. The checklists may also be used for RSV vaccine. The screening checklists are:
* Screening Checklist for Contraindications to Vaccines for Children and Teens ([link removed])
* Screening Checklist for Contraindications to Vaccines for Adults ([link removed])
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Related Links
* Immunize.org: Handouts: Screening Checklists about Vaccine Contraindications and Precautions ([link removed]) main page
* Immunize.org: Handouts for Patients and Staff ([link removed]) main page, where you can sort materials by topic, vaccine, or language
* Immunize.org: Educational Materials for Patients and Staff ([link removed]) —an alphabetical listing of more than 230 ready-to-print staff educational materials and patient handouts
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“Addressing Vaccination Anxiety for Infants: Strategies for Vaccine Recipients and Caregivers”: watch the 3-minute video, part of the Improving the Vaccination Experience Video Series on YouTube
This week’s featured video shares how parents and caregivers can help infants better cope with vaccination distress in our 3-minute video, Addressing Vaccination Anxiety for Infants: Strategies for Vaccine Recipients and Caregivers ([link removed]) , from Immunize.org’s new Improving the Vaccination Experience Video Series. It is available on our YouTube channel ([link removed]) , along with our full collection of quick video answers to popular Ask the Experts ([link removed]) questions.
This week's featured video focuses on our new 1-page resource for parents of infants: Addressing Vaccination Anxiety for Infants and Toddlers: Strategies for Parents and Caregivers ([link removed])
Immunize.org’s series of short videos introduces you to different ways to improve the vaccination experience for infants, children, teens, and adults. Three are for a general audience, and three are for healthcare professionals. As with all Immunize.org resources, these videos are free to download, link, copy, and share.
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Like, follow, and share Immunize.org’s social media accounts and encourage colleagues and others interested in vaccination to do likewise:
* Facebook at ImmunizeOrg ([link removed])
* Instagram at ImmunizeOrg ([link removed])
* LinkedIn at ImmunizeOrg ([link removed])
* X (Twitter) at ImmunizeOrg ([link removed])
* YouTube at ImmunizeOrg ([link removed])
Related Links
* Immunize.org: YouTube channel ([link removed])
* Immunize.org: Handouts for Patients and Staff: Addressing Vaccination Anxiety ([link removed]) main page
* Immunize.org: Improving the Vaccination Experience: Reducing Pain and Anxiety for Children and Adults ([link removed]) on-demand webinar (2/28/23)
* Immunize.org: Improving the Vaccination Experience: Accessible Vaccination for Neurodiverse People at Any Age ([link removed]) on-demand webinar (12/13/22)
* Immunize.org: Screening Checklists ([link removed]) main page (includes screening checklists with questions to screen for a history of fainting or feeling faint and for vaccination-related anxiety)
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FDA advises healthcare providers about administering correct dosage of Moderna COVID-19 Vaccine (2023–2024 Formula) to children age 6 months through 11 years
On November 1, FDA advised healthcare providers ([link removed]) who administer Moderna COVID-19 Vaccine (2023–2024 Formula) ([link removed]) to children age 6 months through 11 years to ensure that the correct volume of the vaccine (0.25 mL) is withdrawn from the vial to give to the vaccine recipient. A portion of the news release appears below.
FDA has become aware that some healthcare providers may not recognize that the single dose vial of Moderna COVID-19 Vaccine (2023–2024 Formula) for use in individuals 6 months through 11 years of age contains notably more than 0.25 mL of the vaccine. Some healthcare providers may be withdrawing the entire contents of the vial to administer to an individual. However, the volume of a single dose of Moderna COVID-19 Vaccine (2023–2024 Formula) is only 0.25 mL.
Read the full news release ([link removed]) .
Related Links
* FDA news release: Important Information about the Correct Dosage and Administration of Moderna COVID-19 Vaccine (2023–2024 Formula) for Individuals 6 Months through 11 Years of Age ([link removed]) (11/1/23)
* FDA: Moderna COVID-19 Vaccine ([link removed]) main page
* FDA: Moderna COVID-19 Vaccine (2023–2024 Formula) Healthcare Provider Fact Sheet ([link removed]) (PDF)
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Institute for Safe Medication Practices warns of potential for vaccine errors related to packaging; remind staff of safety steps
The Institute for Safe Medication Practices ([link removed]) (ISMP) warned of potential for errors involving manufacturer-filled syringes (MFS) in its October 19 issue of ISMP Medication Safety Alert. ISMP is a federally listed Patient Safety Organization ([link removed]) . The error reports involve the following:
* Inadequate labeling: MFS of diluent intended for reconstituting vaccine doses are typically labeled "diluent for reconstitution." Instructions for use call for the reconstituted vaccine to be drawn back into the syringe. Once drawn back into the syringe, reconstituted vaccine is indistinguishable from diluent alone unless the user adds a label to the syringe to indicate its contents. Products vulnerable to this problem include:
+ Merck's M-M-R II (MMR), Varivax (varicella), and ProQuad (MMRV)
+ GSK's Priorix (MMR)
+ Pfizer's Abrysvo (RSVpreF)
* Using the wrong diluent: Instead of the sterile water diluent provided by the manufacturer, liquid influenza vaccine was placed into a vial of lyophilized RSV vaccine. Other lyophilized vaccines could be vulnerable to similar errors.
To prevent these errors, take the following steps:
* Familiarize your staff with vaccine packaging and show them how lack of labels or look-alike packaging could predispose to errors
* Create vaccine-specific auxiliary labels to make adding a label easy. Store these labels with relevant products.
* Keep vaccines and corresponding diluents together whenever storage requirements permit
* If patients need multiple vaccines, start with the vaccine that needs reconstitution. After preparing and labeling that dose, retrieve and prepare the other vaccines.
* Invest time training all staff on new products and new staff on all products
* Provide adequate lighting and counter space
* Encourage distraction-free zones
Related Links
* Institute for Safe Medication Practices website ([link removed])
* ISMP: Healthcare Practitioner’s Vaccine Error Reporting Form ([link removed]) web page
* Immunize.org: Don’t Be Guilty of These Preventable Errors in Vaccine Administration! ([link removed]) (PDF)
* Immunize.org: Don’t Be Guilty of These Preventable Errors in Vaccines Storage and Handling! ([link removed]) (PDF)
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“Vaccination Coverage by Age 24 Months among Children Born in 2019 and 2020—National Immunization Survey-Child, United States, 2020–2022” published in MMWR
CDC published Vaccination Coverage by Age 24 Months among Children Born in 2019 and 2020—National Immunization Survey-Child, United States, 2020–2022 ([link removed]) on November 3 in MMWR. A portion of the summary appears below.
The Advisory Committee on Immunization Practices recommends vaccines against 15 potentially serious diseases by the age of 24 months. . . .
Estimated coverage with most childhood vaccines was similar among children born during 2019–2020 compared with those born during 2017–2018, with only a few exceptions. Disparities in coverage by race and ethnicity, poverty status, insurance status, and urbanicity persist, with a widening of the gap among some subgroups evident over time. . . .
Universal and equitable access to vaccination will require overcoming economic, logistic, and attitudinal obstacles to ensure that all children are protected from vaccine-preventable diseases.
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Access the MMWR article in HTML ([link removed]) or PDF ([link removed]) .
Related Link
* MMWR's main page ([link removed]) provides access to the MMWR family of publications
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Immunize.org updates "Vaccinations Needed during Pregnancy" patient handout to include RSV prevention
Immunize.org, in partnership with American College of Obstetricians and Gynecologists ([link removed]) (ACOG), updated Vaccinations Needed during Pregnancy ([link removed]) , a 1-page handout for patients. This patient education resource now includes the need for RSV prevention through maternal vaccination or infant immunization. It also addresses the need for hepatitis B screening during every pregnancy, and routine HepB vaccination of unvaccinated, susceptible pregnant people. Download and share this important resource with pregnant patients.
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Related Links
* Immunize.org: Handouts: Pregnancy and Vaccines ([link removed]) main page
* Immunize.org: Handouts for Patients and Staff ([link removed]) main page, where you can sort materials by topic, vaccine, or language
* Immunize.org: Educational Materials for Patients and Staff ([link removed]) —an alphabetical listing of more than 230 ready-to-print staff educational materials and patient handouts
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Review your COVID-19 resources with the latest version of Immunize.org’s “Checklist of Current Versions of U.S. COVID-19 Vaccination Guidance and Clinic Support Tools”
Immunize.org reviews and updates the Checklist of Current Versions of U.S. COVID-19 Vaccination Guidance and Clinic Support Tools ([link removed]) at least monthly, prominently indicating when it was last revised at the top of the page. Changes on the November 6 version include the addition of the new COVID-19 mRNA VIS ([link removed]) .
All COVID-19 vaccine providers should review the checklist regularly and download the latest CDC schedule and standing order documents. The checklist is posted on Immunize.org's Vaccines: COVID-19 ([link removed]) main page to help practices stay up to date.
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Related Links
* Immunize.org: Handouts: Standing Orders Templates for Administering Vaccines ([link removed]) main page
* Immunize.org: Handouts for Patients and Staff ([link removed]) main page, where you can sort materials by topic, vaccine, or language
* Immunize.org: Educational Materials for Patients and Staff ([link removed]) —an alphabetical listing of more than 230 ready-to-print staff educational materials and patient handouts
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Veterans Day is November 11. Encourage more veterans to protect themselves with new Health.mil’s seasonal respiratory illness vaccine communication toolkit.
Veteran's Day is observed on November 11. Encourage our service members, veterans, and their families to protect themselves from preventable health threats this year with communications resources from the Health.mil Seasonal Respiratory Illness Vaccine Toolkit: Influenza, COVID-19, and Respiratory Syncytial Virus ([link removed]) . The toolkit offers many images with recommended content for quick and easy posting on social media.
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View toolkit ([link removed]) .
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Influenza activity is low nationally but continues to increase in most parts of the country; encourage vaccination now
CDC’s Weekly U.S. Influenza Surveillance Report, FluView ([link removed]) , provides a valuable snapshot of influenza activity state-by-state.
Influenza Surveillance
For week 43, ending October 28, CDC’s Weekly U.S. Influenza Surveillance Report, FluView ([link removed]) shows that, nationwide, 2.7% of patient visits reported through the Outpatient Influenza-Like Illness Surveillance Network (ILINet) were due to respiratory illness that included fever plus a cough or sore throat (i.e., influenza-like illness [ILI]). The national baseline is 2.5%. The first influenza-associated pediatric death of the current season was reported.
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RESP-NET
Visit the CDC Respiratory Virus Hospitalization Surveillance Network (RESP-NET) ([link removed]) for weekly reports of hospitalizations across the United States due to three vaccine-preventable seasonal respiratory viruses: COVID-19, influenza, and RSV.
Influenza Vaccination Dashboard
CDC's Weekly Flu Vaccination Dashboard ([link removed]) shows that as of October 14, an estimated 19 million doses of flu vaccine were administered in pharmacies, and an estimated 10 million doses were administered in medical offices.
CDC recommends everyone age 6 months and older get annual influenza vaccination. Influenza and other vaccines (e.g., COVID-19 vaccine, RSV vaccine) may be given at the same visit, if needed. Locate influenza and COVID-19 vaccines in your area by entering your zip code in the VaccineFinder on Vaccines.gov ([link removed]) or Vacunas.gov ([link removed]) . To be listed as a provider by VaccineFinder, see the information on this website ([link removed]) .
Related Links
* CDC: Weekly National Flu Vaccination Dashboard ([link removed]) main page
* CDC: FluView ([link removed]) main page
* CDC: RESP-NET ([link removed]) main page
* Immunize.org: free educational materials and patient handouts related to influenza ([link removed])
* Immunize.org: Vaccines: Influenza ([link removed]) main page
* Immunize.org: Ask the Experts: Influenza ([link removed]) main page
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Journalists interview Immunize.org experts
Journalists seek out Immunize.org experts to help explain vaccines to the public and policy makers. We help the media understand and communicate the complex work vaccinators do. Here is a recent citation.
* Salon: The Real Reason the New RSV Shot Is Hard for Some Parents to Find ([link removed]) (11/6/23)
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Vaccines in the news
These recent articles convey the potential risks of vaccine-preventable diseases and the importance of vaccination.
* New York Times: Few Americans Have Gotten the New COVID Shots, C.D.C. Finds ([link removed]) (10/27/23)
* Washington Post: Flu Shots May Protect against the Risk of Alzheimer’s, Related Dementias ([link removed]) (10/25/23)
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Featured Resources
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CDC updates its website on how to implement ACIP’s shared clinical decision-making recommendations, including links to job aids for vaccinators
CDC updated its Shared Clinical Decision-Making Recommendations ([link removed]) (SCDM) web page, which includes links to job aids for vaccinators. The website also includes answers to frequently asked questions to clarify the ACIP’s shared clinical decision-making recommendations.
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Related Links
* CDC: Shared Clinical Decision-Making: HPV Vaccination for Adults Aged 27–45 Years ([link removed]) (PDF)
* CDC: Shared Clinical Decision-Making: Meningococcal B Vaccination ([link removed]) (PDF)
* CDC: Shared Clinical Decision-Making: PCV20 Vaccination for Adults 65 Years or Older ([link removed]) (PDF)
* CDC: Shared Clinical Decision-Making: RSV Vaccination for Adults 60 Years and Older ([link removed]) (PDF)
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CDC adds customizable frames for “Wild to Mild” social media campaign to promote influenza vaccination
CDC's Wild to Mild ([link removed]) social media images are a lighthearted way to promote influenza vaccination. CDC now offers customizable graphic frames you can add to your photos, sample social media graphics, and printable materials.
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Encourage your patients, friends, loved ones, and followers on social media to get themselves and their families an annual influenza vaccine with social media graphics and customizable frames.
Download the social media frames and social media graphics ([link removed]) .
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Hepatitis B Foundation releases guide for implementation of adult universal hepatitis B vaccination and screening
The Hepatitis B Foundation ([link removed]) issued a 17-page document titled Guidance on the Clinical Implementation of Adult Universal Hepatitis B Vaccination and Screening ([link removed]) . The document contains a summary of the updated recommendations, strategies for implementation in different settings, downloadable resources and handouts for providers, and connections to helpful patient and clinical resources.
View and download a copy of the document ([link removed]) .
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Related Links
* Immunize.org: Standing Orders for Administering Hepatitis B Vaccine to Adults ([link removed])
* Immunize.org: Hepatitis B Vaccination and Screening of Adults: Simple Steps to Protect Yourself from Serious Liver Disease ([link removed])
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NFID posts podcast episode featuring Peter Marks, PhD, MD, of the FDA
Infectious IDeas ([link removed]) , a podcast series from the NFID, brings leading experts together for thought-provoking conversations. The latest entry in the series, Operation Warp Speed: Transforming Disease Prevention ([link removed]) , features Peter Marks, PhD, MD. A description from the web page appears below.
In this episode, hosts Marla Dalton, PE, CAE, and William Schaffner, MD, talk with Peter Marks, MD, PhD, director of the Center for Biologics Evaluation and Research (CBER) at the US Food and Drug Administration. He shares his insights on the origin of Operation Warp Speed during the COVID-19 pandemic, efforts to transform the FDA approach to approval and licensure of new vaccines and other prevention tools, and his thoughts on how artificial intelligence can improve future work in disease prevention.
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Notable Publications
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“A Prospective Cohort Study of Preconception COVID-19 Vaccination and Miscarriage” published in Human Reproduction
In the October 20 issue, Human Reproduction published A Prospective Cohort Study of Preconception COVID-19 Vaccination and Miscarriage ([link removed]) . A portion of the abstract appears below.
Among 1815 eligible female participants, 75% had received at least one dose of a COVID-19 vaccine by the time of conception. Almost one-quarter of pregnancies resulted in miscarriage, and 75% of miscarriages occurred <8 weeks’ gestation. . . . COVID-19 vaccination was not associated with increased risk of either early miscarriage (GW [gestational week]: <8) or late miscarriage (GW: 8–19). There was no indication of an increased risk of miscarriage associated with male partner vaccination.
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Upcoming Events
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Virtual: Children’s Hospital of Philadelphia hosts Current Issues in Vaccines webinar titled “Making the Broadest, Longest-Lasting COVID-19 Vaccine” on December 6 at 12:00 p.m. (ET); CE credit offered
The Vaccine Education Center (VEC) at Children's Hospital of Philadelphia (CHOP) will present a 1-hour webinar titled Making the Broadest, Longest-Lasting Covid-19 Vaccine ([link removed]) beginning at 12:00 p.m. (ET) on December 6. Part of its Current Issues in Vaccines ([link removed]) series, the webinar will feature Paul Offit, MD, director of the VEC.
Free continuing education credits (CME, CEU, and CPE) will be available for both the live and archived events.
Register for the webinar ([link removed]) .
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Virtual: Clinical Care Options hosts webinar “Ready, Set, Vaccinate! Clinical Implementation of RSV Vaccination for Older Adults” on December 6 at 12:30 p.m. (ET); CE credit offered
Clinical Care Options will host a webinar titled Ready, Set, Vaccinate! Clinical Implementation of RSV Vaccination for Older Adults ([link removed]) , 12:30–2:00 p.m. (ET) on December 6. This webinar, sponsored by GSK, is intended to improve healthcare professionals’ knowledge and competence regarding RSV infections and vaccines for older adults, including burden of disease, clinical manifestations, risk factors for severe disease, vaccine candidacy, and overcoming vaccination barriers.
Free CME, CE, and CPE credits offered.
Register for the webinar ([link removed] ) .
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For more upcoming events, visit our Calendar of Events ([link removed]) .
Editorial Information
Editor-in-Chief
Kelly L. Moore, MD, MPH
Managing Editor
John D. Grabenstein, RPh, PhD
Associate Editor
Sharon G. Humiston, MD, MPH
Writer/Publication Coordinator
Taryn Chapman, MS
Courtnay Londo, MA
Style and Copy Editor
Marian Deegan, JD
Web Edition Managers
Arkady Shakhnovich
Jermaine Royes
Contributing Writer
Laurel H. Wood, MPA
Technical Reviewer
Kayla Ohlde
About IZ Express
Immunize.org welcomes redistribution of this issue of IZ Express or selected articles.
When you do so, please add a note that Immunize.org is the source of the material and provide a link to this issue ([link removed]) .
IZ Express is supported in part by Grant No. 1NH23IP922654 from the National Center for Immunization and Respiratory Diseases, CDC. Its contents are solely the responsibility of Immunize.org and do not necessarily represent the official views of CDC.
IZ Express Disclaimer ([link removed])
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