Does Ozempic Stop Working Over Time? Why Weight Loss Can Plateau | When could the marathon world record be broken next? | What Resilience Means, and Why It Matters | U.S. high school students’ scores on the ACT college admissions test drop to new 30-year low

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Does Ozempic Stop Working Over Time? Why Weight Loss Can Plateau - The New York Times -

People taking the drug and similar medications will hit an inevitable, and necessary, plateau. Here’s why.

Kimmy Meinecke blamed herself when she stopped losing weight. For two years, she had been taking a weekly injection of Ozempic to control her diabetes. The medication curbed her appetite so much that sometimes all she ate for dinner was a yogurt or cheese and crackers. But then one day, the scale hit 240, 25 pounds below the weight she’d started at, and stayed there.

She was thrilled that her blood sugar levels had come down, an outcome worth the side effects she experienced, including nausea and occasional bouts of vertigo. Still, Ms. Meinecke, a pastor in Spokane, Wash., had expected to lose more weight, and to keep losing it for longer.

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When could the marathon world record be broken next? - The Athletic

Kelvin Kiptum lit the marathoning world aflame Sunday in Chicago, running a record-breaking time of 2:00:35 to take 34 seconds off Eliud Kipchoge’s previous best. In the process, Kiptum took a major stride closer to becoming the first man to break the two-hour barrier in a record-eligible race.

Just two weeks ago, Tigst Assefa demolished the women’s world record when she took more than two minutes off the previous mark in Berlin, finishing in 2:11:53.

Since 2017, the men’s and women’s records have been broken three times each, a historically rapid pace. Kiptum told Olympics.com the world record wasn’t in the plan, “but in the future, I know I can run 2:00 or something like that.” After Sunday’s race, that future is now.

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What Resilience Means, and Why It Matters - Harvard Business Review

A small but intriguing new survey by a pair of British consultants confirms the importance of resilience to business success. Resilience was defined by most as the ability to recover from setbacks, adapt well to change, and keep going in the face of adversity. But when Sarah Bond and Gillian Shapiro asked 835 employees from public, private, and nonprofit firms in Britain what was happening in their own lives that required them to draw on those reserves, they didn’t point to tragedies like the London Tube bombings, appalling business mistakes, the need to keep up with the inexorably accelerating pace of change, or the challenges of the still-difficult economy — they pointed to their co-workers.

A whopping 75% of them said that the biggest drain on their resilience reserves was “managing difficult people or office politics at work.” That was followed closely by stress brought on by overwork and by having to withstand personal criticism.

Over the years, authors have offered an astonishingly wide range of advice to HBR’s readers about bouncing back from setbacks, both large and small. In “The CEO’s Second Act,” for instance, David Nadler observes how, after coming into a difficult situation and saving the day, a CEO will often stumble once the immediate crisis is over. Drawing on outstanding research from Boris Groysberg, Andrew McLean, and Nitin Nohria showing that leaders tend to succeed in a new role only when it’s very similar to the one they’ve just left, Nadler suggests four steps executives must take to learn to become successful in a new way: recognition that their long-honed leadership styles will no longer work; acceptance that it was they who failed in the new role and not outside forces that caused the problem; analysis and understanding of the new type of leadership that’s required; and then decisive action in the new mode.

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U.S. high school students’ scores on the ACT college admissions test drop to new 30-year low - Fortune

High school students’ scores on the ACT college admissions test have dropped to their lowest in more than three decades, showing a lack of student preparedness for college-level coursework, according to the nonprofit organization that administers the test.

Scores have been falling for six consecutive years, but the trend accelerated during the COVID-19 pandemic. Students in the class of 2023 whose scores were reported Wednesday were in their first year of high school when the virus reached the U.S.

“The hard truth is that we are not doing enough to ensure that graduates are truly ready for postsecondary success in college and career,” said Janet Godwin, chief executive officer for the nonprofit ACT.

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